LOCUS       NM_010814               1725 bp    mRNA    linear   ROD 21-AUG-2024
DEFINITION  Mus musculus myelin oligodendrocyte glycoprotein (Mog), mRNA.
ACCESSION   NM_010814
VERSION     NM_010814.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1725)
  AUTHORS   Fiore,F., Alhalaseh,K., Dereddi,R.R., Bodaleo Torres,F., Coban,I.,
            Harb,A. and Agarwal,A.
  TITLE     Norepinephrine regulates calcium signals and fate of
            oligodendrocyte precursor cells in the mouse cerebral cortex
  JOURNAL   Nat Commun 14 (1), 8122 (2023)
   PUBMED   38065932
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1725)
  AUTHORS   Sagan,S.A., Moinfar,Z., Moseley,C.E., Dandekar,R., Spencer,C.M.,
            Verkman,A.S., Ottersen,O.P., Sobel,R.A., Sidney,J., Sette,A.,
            Anderson,M.S., Steinman,L., Wilson,M.R., Sabatino,J.J. Jr. and
            Zamvil,S.S.
  TITLE     T cell deletional tolerance restricts AQP4 but not MOG CNS
            autoimmunity
  JOURNAL   Proc Natl Acad Sci U S A 120 (30), e2306572120 (2023)
   PUBMED   37463205
  REMARK    GeneRIF: T cell deletional tolerance restricts AQP4 but not MOG CNS
            autoimmunity.
REFERENCE   3  (bases 1 to 1725)
  AUTHORS   Campos-Ordonez,T., Gonzalez-Granero,S., Eudave-Patino,M.,
            Buritica,J., Herranz-Perez,V., Garcia-Verdugo,J.M. and
            Gonzalez-Perez,O.
  TITLE     Normal pressure hydrocephalus decreases the proliferation of
            oligodendrocyte progenitor cells and the expression of CNPase and
            MOG proteins in the corpus callosum before behavioral deficits
            occur
  JOURNAL   Exp Neurol 365, 114412 (2023)
   PUBMED   37075967
  REMARK    GeneRIF: Normal pressure hydrocephalus decreases the proliferation
            of oligodendrocyte progenitor cells and the expression of CNPase
            and MOG proteins in the corpus callosum before behavioral deficits
            occur.
REFERENCE   4  (bases 1 to 1725)
  AUTHORS   Zhang,X., Yu,C., Liu,J.Q. and Bai,X.F.
  TITLE     Dendritic cell expression of CD24 contributes to optimal priming of
            T lymphocytes in lymph nodes
  JOURNAL   Front Immunol 14, 1116749 (2023)
   PUBMED   36969215
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1725)
  AUTHORS   Heo,D., Ling,J.P., Molina-Castro,G.C., Langseth,A.J., Waisman,A.,
            Nave,K.A., Mobius,W., Wong,P.C. and Bergles,D.E.
  TITLE     Stage-specific control of oligodendrocyte survival and
            morphogenesis by TDP-43
  JOURNAL   Elife 11, e75230 (2022)
   PUBMED   35311646
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1725)
  AUTHORS   Jones,E.P., Xiao,H., Schultz,R.A., Flaherty,L., Trachtulec,Z.,
            Vincek,V., Larin,Z., Lehrach,H. and Lindahl,K.F.
  TITLE     MHC class I gene organization in > 1.5-Mb YAC contigs from the H2-M
            region
  JOURNAL   Genomics 27 (1), 40-51 (1995)
   PUBMED   7665183
REFERENCE   7  (bases 1 to 1725)
  AUTHORS   Amadou,C., Ribouchon,M.T., Mattei,M.G., Jenkins,N.A., Gilbert,D.J.,
            Copeland,N.G., Avoustin,P. and Pontarotti,P.
  TITLE     Localization of new genes and markers to the distal part of the
            human major histocompatibility complex (MHC) region and comparison
            with the mouse: new insights into the evolution of mammalian
            genomes
  JOURNAL   Genomics 26 (1), 9-20 (1995)
   PUBMED   7782091
REFERENCE   8  (bases 1 to 1725)
  AUTHORS   Pham-Dinh,D., Jones,E.P., Pitiot,G., Della Gaspera,B., Daubas,P.,
            Mallet,J., Le Paslier,D., Fischer Lindahl,K. and Dautigny,A.
  TITLE     Physical mapping of the human and mouse MOG gene at the distal end
            of the MHC class Ib region
  JOURNAL   Immunogenetics 42 (5), 386-391 (1995)
   PUBMED   7590972
REFERENCE   9  (bases 1 to 1725)
  AUTHORS   Daubas,P., Pham-Dinh,D. and Dautigny,A.
  TITLE     Structure and polymorphism of the mouse myelin/oligodendrocyte
            glycoprotein gene
  JOURNAL   Genomics 23 (1), 36-41 (1994)
   PUBMED   7829100
REFERENCE   10 (bases 1 to 1725)
  AUTHORS   Amiguet,P., Gardinier,M.V., Zanetta,J.P. and Matthieu,J.M.
  TITLE     Purification and partial structural and functional characterization
            of mouse myelin/oligodendrocyte glycoprotein
  JOURNAL   J Neurochem 58 (5), 1676-1682 (1992)
   PUBMED   1373175
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY127313.1, BC080860.1, CR956641.9 and CD776673.1.
            
            On Aug 25, 2006 this sequence version replaced NM_010814.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660815.279206.1, BC050763.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN02415132 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-225               BY127313.1         2-226
            226-937             BC080860.1         67-778
            938-1623            CR956641.9         6490-7175
            1624-1725           CD776673.1         1-102               c
FEATURES             Location/Qualifiers
     source          1..1725
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 19.16 cM"
     gene            1..1725
                     /gene="Mog"
                     /gene_synonym="B230317G11Rik"
                     /note="myelin oligodendrocyte glycoprotein"
                     /db_xref="GeneID:17441"
                     /db_xref="MGI:MGI:97435"
     exon            1..287
                     /gene="Mog"
                     /gene_synonym="B230317G11Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             200..943
                     /gene="Mog"
                     /gene_synonym="B230317G11Rik"
                     /codon_start=1
                     /product="myelin-oligodendrocyte glycoprotein precursor"
                     /protein_id="NP_034944.2"
                     /db_xref="CCDS:CCDS28734.1"
                     /db_xref="GeneID:17441"
                     /db_xref="MGI:MGI:97435"
                     /translation="MACLWSFSWPSCFLSLLLLLLLQLSCSYAGQFRVIGPGYPIRAL
                     VGDEAELPCRISPGKNATGMEVGWYRSPFSRVVHLYRNGKDQDAEQAPEYRGRTELLK
                     ETISEGKVTLRIQNVRFSDEGGYTCFFRDHSYQEEAAMELKVEDPFYWVNPGVLTLIA
                     LVPTILLQVSVGLVFLFLQHRLRGKLRAEVENLHRTFDPHFLRVPCWKITLFVIVPVL
                     GPLVALIICYNWLHRRLAGQFLEELRNPF"
     exon            288..635
                     /gene="Mog"
                     /gene_synonym="B230317G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            636..749
                     /gene="Mog"
                     /gene_synonym="B230317G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            750..770
                     /gene="Mog"
                     /gene_synonym="B230317G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            771..791
                     /gene="Mog"
                     /gene_synonym="B230317G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            792..908
                     /gene="Mog"
                     /gene_synonym="B230317G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            909..929
                     /gene="Mog"
                     /gene_synonym="B230317G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            930..1707
                     /gene="Mog"
                     /gene_synonym="B230317G11Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1683..1688
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mog"
                     /gene_synonym="B230317G11Rik"
                     /note="hexamer: AATACA"
     polyA_site      1704
                     /gene="Mog"
                     /gene_synonym="B230317G11Rik"
                     /note="major polyA site"
ORIGIN      
        1 gtacaaatat ctggcaaggg tgacgtgggg ccattcctca gggcacagct gtggtaatgc
       61 ttacatggag gttgggcttg ggcagtagtg ccctcccaga ttctcccttc gggcttcttg
      121 gaggaaggga catgcagccg gaggacctca gcttggcctg accctgctgt tagggactct
      181 gtccccggta accataaaga tggcctgttt gtggagcttc tcttggccca gctgcttcct
      241 ctcccttctc ctcctccttc tcctccagtt gtcatgcagc tatgcaggac aattcagagt
      301 gataggacca gggtatccca tccgggcttt agttggggat gaagcagagc tgccgtgccg
      361 catctctcct gggaaaaatg ccacgggcat ggaggtgggt tggtaccgtt ctcccttctc
      421 aagagtggtt cacctctacc gaaatggcaa ggaccaagat gcagagcaag cacctgaata
      481 ccggggacgc acagagcttc tgaaagagac tatcagtgag ggaaaggtta cccttaggat
      541 tcagaacgtg agattctcag atgaaggagg ctacacctgc ttcttcagag accactctta
      601 ccaagaagag gcagcaatgg agttgaaagt ggaagatccc ttctattggg tcaaccccgg
      661 tgtgctgact ctcatcgcac ttgtgcctac gatcctcctg caggtctctg taggccttgt
      721 attcctcttc ctgcagcaca gactgagagg aaaacttcgt gcagaagtag agaatctcca
      781 tcggactttt gatcctcact tcctgagggt gccctgctgg aagataacac tgtttgttat
      841 tgtgcctgtt cttggacccc tggttgcctt gatcatctgc tacaactggc tgcaccgaag
      901 actggcagga cagtttcttg aagagctaag aaaccccttt tgagtgatgg ttgtgtcttc
      961 ctggagcgga aggagagccc agcaggtcct tggggatttc ccattggcct ctttgctgtg
     1021 gacagattcc aatctacatc tacagacaca ttctggatac cgagtagaac ttgatttccc
     1081 tccctcaact gtctttcctc agctccttcc tctaattttt gacttccaca tcttttttac
     1141 catgttagtc tgactataga aaacaccctg tggtgaaggc caggcagtct atcaggagac
     1201 acctatgcac cagagtaata caggagtgat tctgccaacc aggatacgca gcacttcatc
     1261 attgtgaact atagaacatc aactctgcaa atggtggata tttcttccaa gaccacagcc
     1321 ttgactggga agaatatcaa tgtggggggg ggggggtcag gaacagaaga gcccacaata
     1381 tcggggaaag ctaagtgagc cagggtatga atatgagcac ctgaaccaaa acctggagct
     1441 aaaattcaaa agaataccga ccagagaaat accatcttgc tttggcagcc tggtgggagg
     1501 accttgagaa gcaagggctg agaactgggt ctgctcccct atgttccaca ccttcgtgcc
     1561 cttcataccc ctgcctctca ttttctccta ccttatttct ctgagaacca atgtggtttt
     1621 tttcccccaa aaattactac ttggtggtct accagacaca aacaagctag gtgctaatta
     1681 ataatacaag tttctctgtg catacttaaa aaaaaaaaaa aaaaa
//
