LOCUS       NM_001160330            1691 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus molybdenum cofactor synthesis 3 (Mocs3), mRNA.
ACCESSION   NM_001160330 XM_130596 XM_911841
VERSION     NM_001160330.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1691)
  AUTHORS   Marelja,Z., Mullick Chowdhury,M., Dosche,C., Hille,C., Baumann,O.,
            Lohmannsroben,H.G. and Leimkuhler,S.
  TITLE     The L-cysteine desulfurase NFS1 is localized in the cytosol where
            it provides the sulfur for molybdenum cofactor biosynthesis in
            humans
  JOURNAL   PLoS One 8 (4), e60869 (2013)
   PUBMED   23593335
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1691)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY727851.1, BX005039.11, BE133066.1, BG083535.2 and BE333092.1.
            
            On or before May 21, 2009 this sequence version replaced
            XM_911841.2, XM_130596.6.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: SRR7652917.1203831.1, SRR7974084.220.1
                                        [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-586               BY727851.1         1-586
            587-696             BX005039.11        63454-63563
            697-1177            BE133066.1         1-481
            1178-1438           BG083535.2         77-337
            1439-1520           BX005039.11        64306-64387
            1521-1691           BE333092.1         1-171               c
FEATURES             Location/Qualifiers
     source          1..1691
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 88.5 cM"
     gene            1..1691
                     /gene="Mocs3"
                     /gene_synonym="1700020H17Rik; Uba4"
                     /note="molybdenum cofactor synthesis 3"
                     /db_xref="GeneID:69372"
                     /db_xref="MGI:MGI:1916622"
     exon            1..1682
                     /gene="Mocs3"
                     /gene_synonym="1700020H17Rik; Uba4"
                     /inference="alignment:Splign:2.1.0"
     CDS             14..1396
                     /gene="Mocs3"
                     /gene_synonym="1700020H17Rik; Uba4"
                     /EC_number="2.7.7.80"
                     /EC_number="2.8.1.11"
                     /note="MPT synthase sulfurylase"
                     /codon_start=1
                     /product="adenylyltransferase and sulfurtransferase MOCS3"
                     /protein_id="NP_001153802.1"
                     /db_xref="CCDS:CCDS50802.1"
                     /db_xref="GeneID:69372"
                     /db_xref="MGI:MGI:1916622"
                     /translation="MAAPEDVAALQAEITRREEELASLKRRLAAALTAEPEPERPLRV
                     PPPPLAPRAALSRDEILRYSRQLLLPELGVRGQLRLAAAAVLVVGCGGLGCPLAQYLA
                     AAGVGRLGLVDHDVVETSNLARQVLHGEAQAGESKARSAAAALRRLNSAVECVAYPRA
                     LAEDWALDLVRGYDVVADCCDNVPTRYLVNDACVLAGRPLVSASALRFEGQMTVYHHD
                     GGPCYRCVFPRPPPPETVTNCADGGVLGAVPGVLGCAQALEVLKIAAGLGSSYSGSML
                     LFDGLGGHFRRIRLRRRRPDCVVCGQQPTVTRLQDYEAFCGSSATDKCRALKLLCPEE
                     RISVTDYKRLLDSGAPHVLLDVRPQVEVDICRLPHSLHIPLSQLERRDADSLKLLGAA
                     LRKGKQESQEGVALPVYVICKLGNDSQKAVKVLQSLTAVPELDSLTVQDIVGGLMAWA
                     AKIDGTFPQY"
     regulatory      1664..1669
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mocs3"
                     /gene_synonym="1700020H17Rik; Uba4"
                     /note="hexamer: ATTAAA"
     polyA_site      1682
                     /gene="Mocs3"
                     /gene_synonym="1700020H17Rik; Uba4"
                     /note="major polyA site"
ORIGIN      
        1 ggaagaggct gtcatggctg ccccggagga cgtagctgcc ttacaggctg aaatcacccg
       61 gcgggaggaa gagctagctt cgctcaagcg gaggctggcc gcggccctga cagccgagcc
      121 ggagcccgag cgtccgctcc gggtcccgcc gccgccgctg gcgccccggg ccgcgctgtc
      181 gcgggacgag atcctccgct acagccgcca gctactgctg ccggagctgg gcgtgcgcgg
      241 gcagctgcgc ctggcggcgg cggcggtgct cgtggtgggc tgcggcgggc tgggctgccc
      301 gctggcgcag tacctggcgg cggccggcgt aggcaggctg gggctggtgg accacgacgt
      361 ggtggagacg agcaacctgg cccgccaggt cctgcacggg gaggcgcagg ccggcgagag
      421 caaggctcgc tcggcggccg cggcgctgcg ccgtctcaac tcggcggtgg agtgcgtggc
      481 gtacccgcgc gcgctcgccg aggactgggc gctcgacctg gtccgcggct acgacgtggt
      541 ggcagactgc tgcgacaacg tgcccacgcg ctacctggtg aacgacgcgt gcgtgctggc
      601 cggccggccg ctagtgtcgg ccagcgcgct gcgcttcgag ggccagatga ccgtctacca
      661 ccacgacggc gggccgtgct accgctgcgt gttcccgcgg ccgcccccgc cggagacagt
      721 gaccaactgt gcagacggcg gcgtgctcgg agcggtgccc ggcgtgctag gctgcgcgca
      781 ggccctcgag gtgctcaaga tcgccgccgg cctcggctcc tcctacagcg gcagcatgct
      841 gctcttcgac ggcctcgggg gccacttccg ccggatccgg ctgcggcgcc gccggcctga
      901 ctgcgtcgtg tgcgggcagc agcccaccgt gacccgcctg caggactacg aggccttctg
      961 cggctcctcg gccaccgaca agtgccgcgc cctgaagctg ctgtgccccg aggagcggat
     1021 ttctgtgacc gactacaagc ggcttctgga ttccggggcg ccccatgtgt tgctggacgt
     1081 ccggcctcaa gtagaggtgg acatctgtcg cctgccgcac tctctccaca tccctttgag
     1141 tcagttggaa cgcagggatg cggacagcct gaaactctta ggggctgccc tccggaaagg
     1201 gaagcaggag tcgcaggaag gggttgctct cccggtgtat gtgatttgca aactgggaaa
     1261 cgactcccag aaagctgtga aggtcctgca gtccttaacg gcagtgccgg agttagactc
     1321 tttaactgtt caggacatcg tggggggact catggcctgg gccgccaaaa ttgatgggac
     1381 atttccacag tactgagagg acagcatgtg attcgtgtgg atgacggttg tgatacctga
     1441 agaatctatt cgagctttac aaaataatgt agggaagagc ctggattcac ggtctccgaa
     1501 taaataaacg gagacctccc cccccccccc ccccaaggag ctttttgaga aaagaggata
     1561 gcattgcctc tgagagctac ttttgggcac ttgtgcagca ccttcaacat gtgacttggt
     1621 acgacaggat tttttgtttc ccacccggtc agattaaact gagattaaac agttaagatg
     1681 caaaaaaaaa a
//
