LOCUS       NM_026779               2884 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus molybdenum cofactor sulfurase (Mocos), mRNA.
ACCESSION   NM_026779 XM_484710 XM_985953
VERSION     NM_026779.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2884)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2884)
  AUTHORS   Sedda,D., Mackowiak,C., Pailloux,J., Culerier,E., Dudas,A.,
            Rontani,P., Erard,N., Lefevre,A., Mavel,S., Emond,P., Foucher,F.,
            Le Bert,M., Quesniaux,V.F.J., Mihatsch,M.J., Ryffel,B. and
            Erard-Garcia,M.
  TITLE     Deletion of Mocos Induces Xanthinuria with Obstructive Nephropathy
            and Major Metabolic Disorders in Mice
  JOURNAL   Kidney360 2 (11), 1793-1806 (2021)
   PUBMED   35372998
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2884)
  AUTHORS   Ichida,K., Matsumura,T., Sakuma,R., Hosoya,T. and Nishino,T.
  TITLE     Mutation of human molybdenum cofactor sulfurase gene is responsible
            for classical xanthinuria type II
  JOURNAL   Biochem Biophys Res Commun 282 (5), 1194-1200 (2001)
   PUBMED   11302742
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC113180.1.
            
            On or before Jul 24, 2006 this sequence version replaced
            XM_484710.3, XM_985953.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC113180.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2884
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 13.18 cM"
     gene            1..2884
                     /gene="Mocos"
                     /gene_synonym="1110018O12Rik; HMCS; MCS; MOS"
                     /note="molybdenum cofactor sulfurase"
                     /db_xref="GeneID:68591"
                     /db_xref="MGI:MGI:1915841"
     exon            1..377
                     /gene="Mocos"
                     /gene_synonym="1110018O12Rik; HMCS; MCS; MOS"
                     /inference="alignment:Splign:2.1.0"
     exon            378..467
                     /gene="Mocos"
                     /gene_synonym="1110018O12Rik; HMCS; MCS; MOS"
                     /inference="alignment:Splign:2.1.0"
     exon            468..534
                     /gene="Mocos"
                     /gene_synonym="1110018O12Rik; HMCS; MCS; MOS"
                     /inference="alignment:Splign:2.1.0"
     exon            535..1176
                     /gene="Mocos"
                     /gene_synonym="1110018O12Rik; HMCS; MCS; MOS"
                     /inference="alignment:Splign:2.1.0"
     exon            1177..1253
                     /gene="Mocos"
                     /gene_synonym="1110018O12Rik; HMCS; MCS; MOS"
                     /inference="alignment:Splign:2.1.0"
     exon            1254..1453
                     /gene="Mocos"
                     /gene_synonym="1110018O12Rik; HMCS; MCS; MOS"
                     /inference="alignment:Splign:2.1.0"
     exon            1454..1570
                     /gene="Mocos"
                     /gene_synonym="1110018O12Rik; HMCS; MCS; MOS"
                     /inference="alignment:Splign:2.1.0"
     exon            1571..1996
                     /gene="Mocos"
                     /gene_synonym="1110018O12Rik; HMCS; MCS; MOS"
                     /inference="alignment:Splign:2.1.0"
     exon            1997..2159
                     /gene="Mocos"
                     /gene_synonym="1110018O12Rik; HMCS; MCS; MOS"
                     /inference="alignment:Splign:2.1.0"
     exon            2160..2238
                     /gene="Mocos"
                     /gene_synonym="1110018O12Rik; HMCS; MCS; MOS"
                     /inference="alignment:Splign:2.1.0"
     exon            2239..2363
                     /gene="Mocos"
                     /gene_synonym="1110018O12Rik; HMCS; MCS; MOS"
                     /inference="alignment:Splign:2.1.0"
     exon            2364..2469
                     /gene="Mocos"
                     /gene_synonym="1110018O12Rik; HMCS; MCS; MOS"
                     /inference="alignment:Splign:2.1.0"
     exon            2470..2608
                     /gene="Mocos"
                     /gene_synonym="1110018O12Rik; HMCS; MCS; MOS"
                     /inference="alignment:Splign:2.1.0"
     exon            2609..2713
                     /gene="Mocos"
                     /gene_synonym="1110018O12Rik; HMCS; MCS; MOS"
                     /inference="alignment:Splign:2.1.0"
     exon            2714..2884
                     /gene="Mocos"
                     /gene_synonym="1110018O12Rik; HMCS; MCS; MOS"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgtggcgat gaccgatgac cgcagagtgc gcgaccgggt cctgtcccag gtgggcaaag
       61 gccgcacgga actgaaagct ctccgtgagt cagcgagctt cgaggaggcc ggcctgcgag
      121 gcgccgcccc tgggtgggga cccgagtcac ccggggttca gccctggcga aatcgcctgc
      181 cttgctcact tcccgggctg gacggtctgg atcccgcaga cttcaggcgc gatccatggc
      241 ctgcggggcg gcagagcggg gccctgagcc cccggccttc cagcgccatc tggaagccag
      301 cacacagcgc ttggcccacg gctacggctt gcgcagcatg agcgagctgc gggaccagga
      361 gtttggccgc ctagcaggaa ctgtctacct tgaccatgca ggagccacct tgttccccca
      421 gagccagctc acaaacttca ctaaggatct catggaaaat gtctatggta accctcacag
      481 ccagaacatc accagcaaac tcacccacga cactgtggag caggtccgct acaggatcct
      541 gactcacttt cacaccaccc cagaggacta catcgtgatc ttcacagctg ggagtacagc
      601 tgctctcagg ctagtggcag aggcgtttcc gtgggtgtcc cggagcccag agaacagtgg
      661 gagtcacttc tgctacctca ctgacaacca cacctctgtg gtgggaatga ggaaggtggc
      721 tgcagccatg agtgtcacat ctatcccagt caagccagag gacatgtggt cagcggaggg
      781 aaaggatgct ggagcctgtg accccgactg tcagcttcca cacctcttct gttacccagc
      841 tcagagtaac ttttcgggca ccagataccc attgtcatgg gtagaggagg tcaagtctgg
      901 gcggaggagc cctgtgaatg caccggggaa gtggtttgtg ctgctggatg cagcctccta
      961 tgtcagcact tcccccttgg atctgtcagc tcaccaggct gacttcatcc ccatctcctt
     1021 ctataagatc tttgggctcc ccacaggcct gggtgctctg ctagtcaata agcacgtggc
     1081 tcctctcttg aggaaaggct acttcggagg agggactgca gctgcctacc ttgcaggaga
     1141 ggacttttac gtcccaaggt catcggtggc agaaaggttc gaagatggca ccatctcatt
     1201 cctcgatgta atagcgctga agcatggatt tgatgctctg gagcacctca caggcggcat
     1261 ggtgaacata cagcagcaca ccttcgctct ggtgcagtac actcactctg ccctgtcttc
     1321 cctccgctac ctcaacgggg cccctgtggt gcgcatttac agcgattctg agttcagcag
     1381 ccctgatgtc cagggtccaa tcatcaattt taatgtgttg gatgatggtg ggaagatcat
     1441 tggctactcc caggtggaca aaatggctag cctgtacaac atccacctga ggactggctg
     1501 cttctgtaac ttaggggcct gccagaggca cctggggcta agtgacgaga tggtgaagaa
     1561 acattttcag gcgggtcatg tctgtgggga tgatgttgac attatagatg gacgacccac
     1621 cggctctgtg aggatttcct ttggatacat gtccacacta gaagatgccc aggcctttct
     1681 gaggttcatc agtactatct acctccgctc acccagtgac cagcctgttc ctcaagccag
     1741 catcagtgat gctggggcct taacctcgaa gagtgactgt cactcacctc aggaaggttc
     1801 ctgtacagac ccttcagttt gcaatggctc ctatcctgac acaaacatca tggacttgca
     1861 cccgtctctg agcaaagcca gcagcgccca gcagacccct caagacaaag ctgcaggaat
     1921 cctgaatggg gacccggggt cccacattgt caccaacatt tacctctacc ccatcaaatc
     1981 ctgtgctgcg tttgaggtga ccaagtggcc tgtggggagc caagggctgc tgtatgaccg
     2041 gagctggatg gttgtgaatc acaatggcat ttgcatgagt cagaagcagg agccacggct
     2101 ctgcctgatc cagcccttca ttgacctgca gcagaggatc atggtcatca aagcagaagg
     2161 gatggagcct atccaggtgc ctcttgagga ggatggagaa cagactcaga tttgtcaaag
     2221 cagagtgtgt gctgacaggg taaatactta tgattgtgga gaaaatgttt caagatggct
     2281 gtcaaagttt cttggccgtc tatgtcattt aatcaagcaa agtccacact tccagcgaaa
     2341 tgccaggaag acgcctaaaa aaggtcagcc tcccggtact actgttgccc tgtccttggt
     2401 gaacgaggct cagtatctgc tggtgaacac atcaagtatt ctggagcttc agcggcagtt
     2461 aaatgccagt gacgaacatg gaaaggagga gtcattctcc atgaaagatc tcatctcccg
     2521 cttccgtgcc aatattatta ccaagggagc cagagccttt gaagaagaga agtgggatga
     2581 gatttcaatt ggctccttgc atttccaggt tctagggcct tgccacaggt gccagatgat
     2641 ttgtatcaac cagcaaaccg ggcagcggaa ccaggacgtc ttccagacgc tctccgagag
     2701 tcgggggaga aaggtgaact ttggtgtgta cctgatgcat tcgtacttgg atttatcgtc
     2761 tccatgtttc ctgtcagtgg gatcggaggt gctccccgtg ttgaaagact gtggagtgtc
     2821 ctgattcacc cccttcccag aaacacccaa gtgttgtctc ctaacatttc ttctcccaag
     2881 agca
//
