LOCUS       NM_025283               2845 bp    mRNA    linear   ROD 20-SEP-2024
DEFINITION  Mus musculus MOB family member 4, phocein (Mob4), transcript
            variant 1, mRNA.
ACCESSION   NM_025283
VERSION     NM_025283.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2845)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2845)
  AUTHORS   Chen,Y.K., Chen,C.Y., Hu,H.T. and Hsueh,Y.P.
  TITLE     CTTNBP2, but not CTTNBP2NL, regulates dendritic spinogenesis and
            synaptic distribution of the striatin-PP2A complex
  JOURNAL   Mol Biol Cell 23 (22), 4383-4392 (2012)
   PUBMED   23015759
REFERENCE   3  (bases 1 to 2845)
  AUTHORS   Haeberle,A.M., Castets,F., Bombarde,G., Baillat,G. and Bailly,Y.
  TITLE     Immunogold localization of phocein in dendritic spines
  JOURNAL   J Comp Neurol 495 (3), 336-350 (2006)
   PUBMED   16440294
REFERENCE   4  (bases 1 to 2845)
  AUTHORS   Carninci,P., Waki,K., Shiraki,T., Konno,H., Shibata,K., Itoh,M.,
            Aizawa,K., Arakawa,T., Ishii,Y., Sasaki,D., Bono,H., Kondo,S.,
            Sugahara,Y., Saito,R., Osato,N., Fukuda,S., Sato,K., Watahiki,A.,
            Hirozane-Kishikawa,T., Nakamura,M., Shibata,Y., Yasunishi,A.,
            Kikuchi,N., Yoshiki,A., Kusakabe,M., Gustincich,S., Beisel,K.,
            Pavan,W., Aidinis,V., Nakagawara,A., Held,W.A., Iwata,H., Kono,T.,
            Nakauchi,H., Lyons,P., Wells,C., Hume,D.A., Fagiolini,M.,
            Hensch,T.K., Brinkmeier,M., Camper,S., Hirota,J., Mombaerts,P.,
            Muramatsu,M., Okazaki,Y., Kawai,J. and Hayashizaki,Y.
  TITLE     Targeting a complex transcriptome: the construction of the mouse
            full-length cDNA encyclopedia
  JOURNAL   Genome Res 13 (6B), 1273-1289 (2003)
   PUBMED   12819125
REFERENCE   5  (bases 1 to 2845)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   6  (bases 1 to 2845)
  AUTHORS   Moreno,C.S., Lane,W.S. and Pallas,D.C.
  TITLE     A mammalian homolog of yeast MOB1 is both a member and a putative
            substrate of striatin family-protein phosphatase 2A complexes
  JOURNAL   J Biol Chem 276 (26), 24253-24260 (2001)
   PUBMED   11319234
REFERENCE   7  (bases 1 to 2845)
  AUTHORS   Temeles,G.L., Ram,P.T., Rothstein,J.L. and Schultz,R.M.
  TITLE     Expression patterns of novel genes during mouse preimplantation
            embryogenesis
  JOURNAL   Mol Reprod Dev 37 (2), 121-129 (1994)
   PUBMED   7545925
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY768556.1 and BC052475.1.
            
            On Feb 8, 2007 this sequence version replaced NM_025283.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC052475.1, AK147857.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-55                BY768556.1         1-55
            56-2845             BC052475.1         1-2790
FEATURES             Location/Qualifiers
     source          1..2845
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 28.03 cM"
     gene            1..2845
                     /gene="Mob4"
                     /gene_synonym="2610109B12Rik; Mobkl3; Phocn; Prei3"
                     /note="MOB family member 4, phocein"
                     /db_xref="GeneID:19070"
                     /db_xref="MGI:MGI:104899"
     exon            1..115
                     /gene="Mob4"
                     /gene_synonym="2610109B12Rik; Mobkl3; Phocn; Prei3"
                     /inference="alignment:Splign:2.1.0"
     CDS             56..733
                     /gene="Mob4"
                     /gene_synonym="2610109B12Rik; Mobkl3; Phocn; Prei3"
                     /note="isoform 1 is encoded by transcript variant 1; mps
                     one binder kinase activator-like 3; mob3; class II mMOB1;
                     mob1 homolog 3; preimplantation protein 3; MOB1, Mps One
                     Binder kinase activator-like 3; mob-like protein phocein"
                     /codon_start=1
                     /product="MOB-like protein phocein isoform 1"
                     /protein_id="NP_079559.2"
                     /db_xref="CCDS:CCDS14960.1"
                     /db_xref="GeneID:19070"
                     /db_xref="MGI:MGI:104899"
                     /translation="MVMAEGTAVLRRNRPGTKAQDFYNWPDESFDEMDSTLAVQQYIQ
                     QNIRADCSNIDKILEPPEGQDEGVWKYEHLRQFCLELNGLAVKLQSECHPDTCTQMTA
                     TEQWIFLCAAHKTPKECPAIDYTRHTLDGAACLLNSNKYFPSRVSIKESSVAKLGSVC
                     RRIYRIFSHAYFHHRQIFDEYENETFLCHRFTKFVMKYNLMSKDNLIVPILEEEVQNS
                     VSGESEA"
     exon            116..178
                     /gene="Mob4"
                     /gene_synonym="2610109B12Rik; Mobkl3; Phocn; Prei3"
                     /inference="alignment:Splign:2.1.0"
     exon            179..279
                     /gene="Mob4"
                     /gene_synonym="2610109B12Rik; Mobkl3; Phocn; Prei3"
                     /inference="alignment:Splign:2.1.0"
     exon            280..322
                     /gene="Mob4"
                     /gene_synonym="2610109B12Rik; Mobkl3; Phocn; Prei3"
                     /inference="alignment:Splign:2.1.0"
     exon            323..409
                     /gene="Mob4"
                     /gene_synonym="2610109B12Rik; Mobkl3; Phocn; Prei3"
                     /inference="alignment:Splign:2.1.0"
     exon            410..489
                     /gene="Mob4"
                     /gene_synonym="2610109B12Rik; Mobkl3; Phocn; Prei3"
                     /inference="alignment:Splign:2.1.0"
     exon            490..601
                     /gene="Mob4"
                     /gene_synonym="2610109B12Rik; Mobkl3; Phocn; Prei3"
                     /inference="alignment:Splign:2.1.0"
     exon            602..2826
                     /gene="Mob4"
                     /gene_synonym="2610109B12Rik; Mobkl3; Phocn; Prei3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      978..983
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mob4"
                     /gene_synonym="2610109B12Rik; Mobkl3; Phocn; Prei3"
                     /note="hexamer: AATAAA"
     polyA_site      1003
                     /gene="Mob4"
                     /gene_synonym="2610109B12Rik; Mobkl3; Phocn; Prei3"
                     /note="major polyA site"
     regulatory      2747..2752
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mob4"
                     /gene_synonym="2610109B12Rik; Mobkl3; Phocn; Prei3"
                     /note="hexamer: AATAAA"
     polyA_site      2775
                     /gene="Mob4"
                     /gene_synonym="2610109B12Rik; Mobkl3; Phocn; Prei3"
     regulatory      2809..2814
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mob4"
                     /gene_synonym="2610109B12Rik; Mobkl3; Phocn; Prei3"
                     /note="hexamer: CATAAA"
     polyA_site      2826
                     /gene="Mob4"
                     /gene_synonym="2610109B12Rik; Mobkl3; Phocn; Prei3"
ORIGIN      
        1 aagctgccgg cccccacatc cgggtaccga cgccagccgc ccagactctg gcactatggt
       61 catggcggag gggacggcag tgctgaggcg gaacaggcca ggcaccaagg cgcaggattt
      121 ctataattgg cctgatgaat catttgatga aatggacagt acacttgctg ttcagcagta
      181 tattcaacag aacataaggg cagactgctc caatattgac aaaattcttg aaccacctga
      241 aggccaagat gaaggtgtat ggaagtatga acatttaagg caattctgcc ttgaactaaa
      301 tggacttgct gtcaaacttc agagtgaatg ccatccagat acctgtactc agatgacagc
      361 aactgaacaa tggatttttc tttgtgcagc tcataaaact ccaaaagagt gtcctgccat
      421 agattataca agacacacac tggatggtgc tgcatgtctt ctgaatagca ataaatattt
      481 tcccagcagg gttagcataa aagaatcatc tgtagcaaaa ctaggatcag tgtgccgtag
      541 gatttataga atattttcac atgcctattt tcatcaccgg cagatatttg atgaatatga
      601 aaatgaaaca tttttatgtc atcggtttac caaatttgtg atgaaatata atctgatgtc
      661 gaaggataac ctgattgtac caattttaga agaggaagtt cagaactcag tttctgggga
      721 aagtgaagca tgaaggaatc acgtagaaca atgtactgat cacataatta acaatgatgt
      781 actgtatata tatcatttta gacacatcaa tcatgtatcc atattatagc ttatttgttt
      841 agtataggtt tttgtatgct atgtgttgcc tttttaaatg ggaaatacat tttaagttat
      901 tcatgagctg tatattcact ggtgtggcac tcatggtttt taaatcagtt tagtattatc
      961 tgttgataat gcctgttaat aaaagacttt acagtttggt aaatgctgct aaacaatcat
     1021 tggaccccag tccttccaat ctataaacga atgagcttgt gtttcacaca agcacctaac
     1081 aagtactaaa gacagcatat ttgctttgtt ttcatcccta agttttaatt taatttaatt
     1141 ttagaaaact cagtagtatt ccatctatac tgttaacttt tccaaaatga gataaaagtg
     1201 tttaaaagtt ctgtctatag catttgatct gcataacgat tatgtgtatg ttcagaggaa
     1261 ctcgaggagc tgttagtgat acttaagctc tctcctacat aaagtgtact ccaggccagt
     1321 gtacttggaa acattgcctg ttttgtgaca gtggattatt aagtccatgg tgacagtgac
     1381 aaggcacaaa cgtgatgttc catggacttg ccccctcttg tttcccttag tcctctggga
     1441 agtacactag tcaggaaatt tatttaccga actatagtta gtgatggcgc ttccctattt
     1501 atatttgtat taattgctta caaagcatac ctcatactag cagtgatgtt acactacagg
     1561 aaaactgtac tgtacaggaa aactgtactg cctacctttg atttttgaaa ttgttgtaac
     1621 tacttagaaa atagtcctta atatagtttg acttttcctt ttagtaatat taatcttttc
     1681 acctaaccct aggcagcatt aaatagatat gaaaaaagat agtgtattaa ttttattttc
     1741 cctccttaaa agcttattat ttgaattata tgcacatgta agactattta caataattca
     1801 caggttaagt ggtgttgata agtggtcata ctttgatttc ttatttcatc gtcttaagaa
     1861 tttaagtgca gccgggcggt ggtggcgcac gcctttaatc ccagcacttg ggaggcagag
     1921 gcaggtggat ttctgagttg gaggccagcc tggtctacaa agtgagttcc aggacagcca
     1981 gggctacaca gagaaaccct gtctcagaaa accaaaaaaa aaaaaaaaaa aagaaaagaa
     2041 aagaaaaaaa aaaaaaagaa tttaagtgca gacttacata acatgacatg attagtggag
     2101 tttctcatta aacgctgagg tctctatgcc acactgtaac aaggcactaa gacagaatag
     2161 agacctgtgc agttgggaca gctgaagcca tctttaccaa tttaacaaaa gaaacttcat
     2221 ttttatttaa gagctatttg cgaatgaaat tgaaaaatgc attcatcttg tttgtttttc
     2281 taattatttg aagaaatgat ttgtattgta ttataagaca agtatacaca gacaaattgg
     2341 gaaatgacag cacactgaga gtgtgtgtag agttgacgcc tgtcagagcc tgtgctgtgc
     2401 cagtggtcac ggtcatcact gtacctgagc ccacagttat cttctaagaa gttatgtttg
     2461 cagtgaatag aacattgact gaaattaggt gtttatatta ctgtcaccat gaatcattgg
     2521 ggttagtaat ttttaaataa acctggtaaa tatccgagag actaacctat actaagttca
     2581 taaattatac ctagtgtagc aatgttgctg ttctctagtt ggagtctcac ggtgggtttc
     2641 tgtcatctga ctgtttctca ggggacagtt acggtagtga ttgggttgtg ggtgtgactg
     2701 agtaattgga acactttgtg aatatatggc ttagtgttaa caggaaaata aagtatggtt
     2761 ttctttttat acttactcca ccctccctgt agtatgtttg aaattgatca taaatctgca
     2821 aaagcaaaaa aaaaaaaaaa aaaaa
//
