LOCUS       NM_028308               1456 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus MOB kinase activator 2 (Mob2), transcript variant 1,
            mRNA.
ACCESSION   NM_028308
VERSION     NM_028308.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1456)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1456)
  AUTHORS   Fan,M., Liu,Y., Shang,Y., Xue,Y., Liang,J. and Huang,Z.
  TITLE     JADE2 Is Essential for Hippocampal Synaptic Plasticity and
            Cognitive Functions in Mice
  JOURNAL   Biol Psychiatry 92 (10), 800-814 (2022)
   PUBMED   36008159
REFERENCE   3  (bases 1 to 1456)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 1456)
  AUTHORS   Lin,C.H., Hsieh,M. and Fan,S.S.
  TITLE     The promotion of neurite formation in Neuro2A cells by mouse Mob2
            protein
  JOURNAL   FEBS Lett 585 (3), 523-530 (2011)
   PUBMED   21237165
  REMARK    GeneRIF: study identified Mob2 protein which plays a significant
            role in promoting neurite formation in Neuro2A (N2A) cells
REFERENCE   5  (bases 1 to 1456)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL603836.13.
            
            On Nov 17, 2006 this sequence version replaced NM_028308.1.
            
            Transcript Variant: This variant (1) encodes the isoform 1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF228503.1, BC037588.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382, SAMN00849385
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-50                AL603836.13        116570-116619
            51-211              AL603836.13        161099-161259
            212-305             AL603836.13        161432-161525
            306-430             AL603836.13        167227-167351
            431-1456            AL603836.13        168026-169051
FEATURES             Location/Qualifiers
     source          1..1456
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 87.5 cM"
     gene            1..1456
                     /gene="Mob2"
                     /gene_synonym="1110017M21Rik; 2700078K21Rik; Mmh"
                     /note="MOB kinase activator 2"
                     /db_xref="GeneID:101513"
                     /db_xref="MGI:MGI:1919891"
     exon            1..50
                     /gene="Mob2"
                     /gene_synonym="1110017M21Rik; 2700078K21Rik; Mmh"
                     /inference="alignment:Splign:2.1.0"
     CDS             34..741
                     /gene="Mob2"
                     /gene_synonym="1110017M21Rik; 2700078K21Rik; Mmh"
                     /note="isoform 1 is encoded by transcript variant 1; Mps
                     one binder kinase activator-like 2; ovary-specific
                     MOB-like protein; mob2 homolog"
                     /codon_start=1
                     /product="MOB kinase activator 2 isoform 1"
                     /protein_id="NP_082584.1"
                     /db_xref="CCDS:CCDS40190.1"
                     /db_xref="GeneID:101513"
                     /db_xref="MGI:MGI:1919891"
                     /translation="MDWLMGKSKAKPNGKKPAAEEKKVYLEPEHTKSRITDFEFKELV
                     VLPREIDLNEWLASNTTTFFHHINLQYSTISEFCTGETCQTMAVCNTQYYWYDERGKK
                     VKCTAPQYVDFVMSSVQKLVTDEDVFPTKYGREFPSSFESLVKKICKYLFHVLGHIYW
                     AHFKETLALELHGHLNTLYVHFILFAREFNLLDPKETAVMDDLTEVLCSSPGNSGATG
                     DGANSGASGAQNHVKER"
     exon            51..211
                     /gene="Mob2"
                     /gene_synonym="1110017M21Rik; 2700078K21Rik; Mmh"
                     /inference="alignment:Splign:2.1.0"
     exon            212..305
                     /gene="Mob2"
                     /gene_synonym="1110017M21Rik; 2700078K21Rik; Mmh"
                     /inference="alignment:Splign:2.1.0"
     exon            306..430
                     /gene="Mob2"
                     /gene_synonym="1110017M21Rik; 2700078K21Rik; Mmh"
                     /inference="alignment:Splign:2.1.0"
     exon            431..1456
                     /gene="Mob2"
                     /gene_synonym="1110017M21Rik; 2700078K21Rik; Mmh"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgaggccgag cgaggcgcgg gctccgcgca gccatggact ggctcatggg gaagtctaaa
       61 gctaagccaa acggcaagaa acctgctgca gaggagaaga aggtgtacct ggagccggag
      121 cacaccaaat ccaggatcac tgactttgaa ttcaaggagc tggtagtgct gccccgggag
      181 atcgacctca acgagtggct ggccagcaac acaacaacat tttttcacca catcaacctg
      241 cagtatagca caatctcaga attttgcaca ggagagacgt gtcagacaat ggctgtgtgc
      301 aacacacaat actactggta tgatgagcgg gggaagaagg tcaagtgcac tgccccccag
      361 tatgttgact ttgtcatgag ctctgtgcag aagctggtaa ctgatgaaga tgtgttcccc
      421 acaaaatacg gcagagaatt ccccagctcc ttcgagtcct tggtgaagaa gatctgcaag
      481 tatctgtttc acgtgttggg ccacatctac tgggcccact tcaaggagac cctggccctt
      541 gagctgcatg gacacttgaa cacactgtac gtgcatttca tcctctttgc cagagagttc
      601 aacctgcttg accccaaaga aaccgctgtc atggacgacc tcactgaggt gctgtgcagc
      661 agcccgggta acagtggtgc cactggggat ggggccaaca gtggagcttc tggagcacag
      721 aaccacgtga aggagagatg agtttccagg gccagatggg tgcacatgtg caaaaagaca
      781 actgtgtgtc tgtgtgtgcg cacacatgcc cgggcgtgct ggtggcaagg tctgagggcc
      841 ccgggctgct cagagtgtgg gcttcatgga tgccgctgga gtcaaggcgt gtttcctgac
      901 ttccctgttg gatggatgag tgctgtttgt agtgaagagc ctttggagtc attcattcat
      961 tcaacaaaca tttattggac tgatgttttg atttttcttc tgtggggttt tcctttcttg
     1021 ggtcttccat gtggctcttg ccttcccccc actcccgggg tggggggagc tctgcggctt
     1081 tgaaaggagc accttgtgag aggtgtctcc cccttatggg gcttgccctg cagatctgga
     1141 gttctgctgt gctttgggga tgggctctta cagaggcctg ccctgcagct ttcctcccta
     1201 gctcttgcct ggatcttggc tcagagtccc tggggtagag aagtctgcct ggggtgaccc
     1261 aggagggccc acacctgctg cttgctccta ttaccccttc ttgctgcctc ctcagtgccc
     1321 aaggaggccc caattgtgcg taggggccag ggcagcccag gactggctga ggccctgtgt
     1381 ggagacaggg ctatcagcga aaggcagaat ctgctttagt tcatctgttc agacataata
     1441 aacattctct caggtc
//
