LOCUS       NM_001400322            2067 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus myeloid nuclear differentiation antigen like (Mndal),
            transcript variant 5, mRNA.
ACCESSION   NM_001400322 XM_036165497
VERSION     NM_001400322.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2067)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2067)
  AUTHORS   Brunette,R.L., Young,J.M., Whitley,D.G., Brodsky,I.E., Malik,H.S.
            and Stetson,D.B.
  TITLE     Extensive evolutionary and functional diversity among mammalian
            AIM2-like receptors
  JOURNAL   J Exp Med 209 (11), 1969-1983 (2012)
   PUBMED   23045604
REFERENCE   3  (bases 1 to 2067)
  AUTHORS   Cridland,J.A., Curley,E.Z., Wykes,M.N., Schroder,K., Sweet,M.J.,
            Roberts,T.L., Ragan,M.A., Kassahn,K.S. and Stacey,K.J.
  TITLE     The mammalian PYHIN gene family: phylogeny, evolution and
            expression
  JOURNAL   BMC Evol Biol 12, 140 (2012)
   PUBMED   22871040
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2067)
  AUTHORS   Zhang,K., Kagan,D., DuBois,W., Robinson,R., Bliskovsky,V.,
            Vass,W.C., Zhang,S. and Mock,B.A.
  TITLE     Mndal, a new interferon-inducible family member, is highly
            polymorphic, suppresses cell growth, and may modify plasmacytoma
            susceptibility
  JOURNAL   Blood 114 (14), 2952-2960 (2009)
   PUBMED   19654412
  REMARK    GeneRIF: Mndal acts as a tumor suppressor and displays
            haploinsufficiency
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC170584.4.
            
            On Jan 21, 2022 this sequence version replaced XM_036165497.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5286962.22481.1,
                                           SRR5189679.123526.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-234               AC170584.4         122186-122419
            235-547             AC170584.4         126456-126768
            548-669             AC170584.4         127872-127993
            670-837             AC170584.4         129325-129492
            838-1005            AC170584.4         130799-130966
            1006-1164           AC170584.4         136787-136945
            1165-1587           AC170584.4         139461-139883
            1588-1776           AC170584.4         141980-142168
            1777-2067           AC170584.4         144834-145124
FEATURES             Location/Qualifiers
     source          1..2067
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 80.71 cM"
     gene            1..2067
                     /gene="Mndal"
                     /gene_synonym="100040462; Gm2785; Ifi212"
                     /note="myeloid nuclear differentiation antigen like"
                     /db_xref="GeneID:100040462"
                     /db_xref="MGI:MGI:3780953"
     exon            1..234
                     /gene="Mndal"
                     /gene_synonym="100040462; Gm2785; Ifi212"
                     /inference="alignment:Splign:2.1.0"
     exon            235..547
                     /gene="Mndal"
                     /gene_synonym="100040462; Gm2785; Ifi212"
                     /inference="alignment:Splign:2.1.0"
     CDS             286..1902
                     /gene="Mndal"
                     /gene_synonym="100040462; Gm2785; Ifi212"
                     /note="isoform 1 is encoded by transcript variant 5;
                     myeloid cell nuclear differentiation antigen-like protein"
                     /codon_start=1
                     /product="myeloid cell nuclear differentiation
                     antigen-like protein isoform 1"
                     /protein_id="NP_001387251.1"
                     /db_xref="GeneID:100040462"
                     /db_xref="MGI:MGI:3780953"
                     /translation="MAEYKKIVLLKGLESMEDYQFRTVKSLLRKELKLTKKLQEDYDR
                     IQLADWMEDKFPKYAGLDKLIKVCEHIKDLKDLAKKLKTEKAKVQKKKQGKCKTAVKK
                     KGQDELSSSESLFINKESYKSVPSSKKKGKAIAKTEGEKKNKLTQDQDHLPETSGTDI
                     KTEEDCLQNSPKPPPTSPSSSSNKKKRKEITKTEGGKKKKLTQEQAQLPEPLGTDIKK
                     DEDCLQTPPKPPPTPPSSSLNKKRKSRREEETGVKKSKAAKEPDQPPCCEEPTARCQS
                     PILHSSSSASSNIPSATNQKPQPQNQNIPRGAVLHSEPLTVMVLTATDPFEYESPEHE
                     VKNMFHATVATVSQYFHVKVFNINLKEKFTKKNFIIISNYFESKGILEINETSSVLKA
                     DPDQMIEVPNNIIRNANASPKICDIQKGTSGAVFYGVFTLHKKKVKTQNTSYEIKDGS
                     GSIEVEGSGQWHNINCKEGDKLHLFCFHLKRERGQPKLVCGDHSFVKIKVTKAGKKKE
                     ASTVLSSTKNEEENNYPKDGIKVEMPDYHV"
     exon            548..669
                     /gene="Mndal"
                     /gene_synonym="100040462; Gm2785; Ifi212"
                     /inference="alignment:Splign:2.1.0"
     exon            670..837
                     /gene="Mndal"
                     /gene_synonym="100040462; Gm2785; Ifi212"
                     /inference="alignment:Splign:2.1.0"
     exon            838..1005
                     /gene="Mndal"
                     /gene_synonym="100040462; Gm2785; Ifi212"
                     /inference="alignment:Splign:2.1.0"
     exon            1006..1164
                     /gene="Mndal"
                     /gene_synonym="100040462; Gm2785; Ifi212"
                     /inference="alignment:Splign:2.1.0"
     exon            1165..1587
                     /gene="Mndal"
                     /gene_synonym="100040462; Gm2785; Ifi212"
                     /inference="alignment:Splign:2.1.0"
     exon            1588..1776
                     /gene="Mndal"
                     /gene_synonym="100040462; Gm2785; Ifi212"
                     /inference="alignment:Splign:2.1.0"
     exon            1777..2067
                     /gene="Mndal"
                     /gene_synonym="100040462; Gm2785; Ifi212"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2009..2014
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mndal"
                     /gene_synonym="100040462; Gm2785; Ifi212"
                     /note="hexamer: AATAAA"
     polyA_site      2042
                     /gene="Mndal"
                     /gene_synonym="100040462; Gm2785; Ifi212"
                     /note="major polyA site"
     regulatory      2044..2049
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mndal"
                     /gene_synonym="100040462; Gm2785; Ifi212"
                     /note="hexamer: AATAAA"
     polyA_site      2065
                     /gene="Mndal"
                     /gene_synonym="100040462; Gm2785; Ifi212"
                     /note="major polyA site"
ORIGIN      
        1 agcacactgt aaggcatcca gccctgctaa agctagaaac ttactttaac cagttctctt
       61 gcccccctcc ctgttatttt gtaaatacta cattttctca gcatttaatg agattgcaat
      121 gcattctggt gtactttttt gagtcatttc tctttctact caaaacagag aaaccccatt
      181 tcctgacttg ctgaagattt atcatctgaa cattgctgag aaatttccac ggaggttttg
      241 tctttgtttt tttttttttt aggttaatct ataatttgag agacgatggc tgaatacaag
      301 aaaattgttc ttctaaaagg attagaaagc atggaggact atcagtttag gacagtcaag
      361 tccttactaa gaaaagaact aaaacttact aaaaaattgc aagaagatta tgataggatt
      421 cagctggcgg actggatgga ggacaagttc cccaaatatg ctggactaga caaactgata
      481 aaagtgtgtg agcacataaa agatcttaaa gaccttgcta aaaaacttaa aaccgagaag
      541 gcaaaagttc aaaagaaaaa gcaaggaaaa tgcaaaacgg ctgtgaaaaa aaaaggtcaa
      601 gatgaactca gttcctccga atctcttttc atcaataaag aatcatacaa gagtgtaccg
      661 tcttcaaaga aaaagggaaa agcgatcgca aaaactgaag gtgaaaaaaa aaataagctc
      721 acccaggatc aggatcatct tccagaaact tcaggaaccg atataaaaac agaggaagat
      781 tgtctccaga attctcctaa gcctccacca acatcaccca gcagttcctc aaacaagaaa
      841 aagagaaaag agatcacaaa aactgaaggt ggaaagaaaa agaagctcac ccaggagcag
      901 gctcagcttc cagaaccttt aggaactgat ataaaaaagg atgaagattg cctccagact
      961 cctcctaagc ctccaccaac accacccagc agttccttaa acaagaaaag aaaaagtagg
     1021 agagaagaag agactggagt gaaaaagagc aaggcggcta aggaaccaga tcagcctccc
     1081 tgttgtgaag aacccacagc caggtgccag tcaccaatac tccacagctc atcttcagct
     1141 tcatctaaca ttccttcagc tacgaaccaa aaaccacaac cccagaacca gaacattccc
     1201 agaggtgctg ttctccactc agagcccctg acagtgatgg tgctcactgc aacagacccg
     1261 tttgaatatg aatcaccaga acatgaagta aagaacatgt ttcatgctac agtggctaca
     1321 gtgagccagt atttccatgt gaaagttttc aacatcaact tgaaagagaa gttcacaaaa
     1381 aagaatttta tcatcatatc caattacttt gagagcaaag gcatcctgga gatcaatgag
     1441 acttcctctg tgttaaaggc tgatcctgac caaatgattg aagtgcccaa caatattatc
     1501 agaaatgcaa atgccagtcc taagatctgt gatattcaaa agggtacttc tggagcagtg
     1561 ttctatggag tgtttacatt acacaagaaa aaagtgaaaa cacagaacac aagctatgaa
     1621 ataaaagatg gttcaggaag tatagaagtg gaggggagtg gacaatggca caacatcaac
     1681 tgtaaggaag gagataagct ccacctcttc tgctttcacc tgaaaagaga aagaggacaa
     1741 ccaaagttag tgtgtggaga ccacagtttc gtcaagatca aggtcaccaa ggctgggaaa
     1801 aaaaaggaag catcaactgt cctgtcaagc acaaaaaatg aagaagaaaa taattaccca
     1861 aaagatggaa ttaaggtaga gatgccagac tatcacgtct aaatgacagc tttagtagta
     1921 tatccaagca tttaataacc ttcatacctg atttctgatt ttgtattttc atttgaaaaa
     1981 atttcttatt gttctgtttt tctatgaaaa taaaatttga tttaatttct ctactgtaaa
     2041 aataataaac atgtcttttt aaaggga
//
