LOCUS       NM_175002               1883 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus membrane magnesium transporter 2 (Mmgt2), mRNA.
ACCESSION   NM_175002 XM_001001763 XM_618882 XM_901503 XM_906807
VERSION     NM_175002.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1883)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1883)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   3  (bases 1 to 1883)
  AUTHORS   Goytain,A. and Quamme,G.A.
  TITLE     Identification and characterization of a novel family of membrane
            magnesium transporters, MMgT1 and MMgT2
  JOURNAL   Am J Physiol Cell Physiol 294 (2), C495-C502 (2008)
   PUBMED   18057121
  REMARK    GeneRIF: These experiments suggest that MMgT proteins may provide
            regulated pathways for Mg(2+) transport in the Golgi and post-Golgi
            organelles of epithelium-derived cells.(MMgT1 PROTEIN, MOUSE)
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB871237.1, AK131977.1 and AL596181.10.
            
            On or before Jul 25, 2007 this sequence version replaced
            XM_001001763.2, XM_906807.3, XM_618882.4, XM_901503.3, NM_175002.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK131977.1, AV113933.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-153               BB871237.1         2-154
            154-846             AK131977.1         44-736
            847-1883            AL596181.10        7792-8828           c
FEATURES             Location/Qualifiers
     source          1..1883
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 38.56 cM"
     gene            1..1883
                     /gene="Mmgt2"
                     /note="membrane magnesium transporter 2"
                     /db_xref="GeneID:216829"
                     /db_xref="MGI:MGI:2448491"
     exon            1..193
                     /gene="Mmgt2"
                     /inference="alignment:Splign:2.1.0"
     exon            194..1883
                     /gene="Mmgt2"
                     /inference="alignment:Splign:2.1.0"
     CDS             352..723
                     /gene="Mmgt2"
                     /codon_start=1
                     /product="membrane magnesium transporter 2"
                     /protein_id="NP_778167.1"
                     /db_xref="CCDS:CCDS36179.1"
                     /db_xref="GeneID:216829"
                     /db_xref="MGI:MGI:2448491"
                     /translation="MVAWLWKVLMGVGLFALTHAAFSAAQHRSHARLTEKKYEPLPAD
                     IVLQTLLAFALTCYGVVHTAGDFRDRDATSELKDMTFDTLRNRPSFYVFHRSGYRLFQ
                     RPDSTHSSNLSASSSDLPLKF"
     regulatory      1859..1864
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mmgt2"
                     /note="hexamer: AATAAA"
     polyA_site      1880
                     /gene="Mmgt2"
                     /note="major polyA site"
ORIGIN      
        1 gcgtgtctcc ctccctctcc ggcgcccgct ccttcccgcc gcgcggctct gggctagggg
       61 tgcccggcgc ccccgccctg ctttgtccct ggtgcagcgc cccctgccgg acactgtgct
      121 gcgcctcttg gggcccgcgg cttcctggca aaggtcagtg agttccccga tgctttcctg
      181 actgcgcgcc tagtggccgt gagctaagtg atcccacctt gatgtactgc gctgctacag
      241 gtccaaagtg acgaggccag acgagactga accaagacaa gtctttcatt tccttagcat
      301 atttatccca gtgtggaagg ctagctctgg ggcagcgatt ccttcggaac catggtggcg
      361 tggctgtgga aggtgctgat gggcgtcggt ctcttcgccc tcacccacgc ggccttctca
      421 gctgctcagc atcgctctca tgcgcgactg acagaaaaga agtatgagcc gctgccggcg
      481 gatatagttc tccagaccct tttggccttt gcgcttacct gttacggcgt ggttcatact
      541 gcaggggact ttagagacag ggatgccact tcggaactaa aggatatgac atttgacacc
      601 ttaaggaatc gcccgtcttt ttacgtgttt caccgttctg gctaccgact gttccagcgt
      661 ccggattcaa cccattcttc aaacctcagc gcgtcatctt ctgacttacc gttgaagttt
      721 tgaaagctca aatcaccgca ccattcagct ttttaacgag ttaagtaaca ggacagacgc
      781 agaattaagt accgggattt gggatgtgaa acacccccaa cacatcagta tttttactga
      841 tatttcagac ttaattaaaa aaaaaaaagc tctataaata aataaataaa taagagatat
      901 ttatgccagg tacccagtca cagctgtaga acgctgatta actgtggatt tgtttttggg
      961 tgaggtaaac atttgaatct tggcccaggt aaagcagata ctgcaggtgg cccttacccc
     1021 ggccatccag gggctggata gaacaaaaag gcctcagtaa ggaagacatg cttttgcatg
     1081 cttgaacttt cgatctttct ttggctctgt cccctaaacc cagacatgaa ctcttcttac
     1141 attctgagcc tgtgagacta aacttgcatg tgggctctcc tgagtctgtg cactgattac
     1201 agtcttgaag gaactggaag gttttcacaa tgtctgattt gattcttcat tccgactctc
     1261 accacaggtt cctcctgggc tctcagactg atgatctgga ggccgctgtg agctataagc
     1321 tcggagatgg cgatgatttt ccatgctggg tgaagaggcc taactgaagt agagaaaggc
     1381 cagcattccc agaatagtgc acataagagg tggaagagcc ttgccccttc caagctagct
     1441 acccctgtcg ccagttccac gtgctgcttg ctgtgggctg attgtatgcc cacttctctt
     1501 tttgctgcgg ttccatacga gattttgcca tttgcaaatg tattaaggtt tgtcagagga
     1561 ctggaatcaa ggaggggaat gtgtttatat aaaactgtcc cctggtgtct gcaggggatt
     1621 gactctgtcg ccatgtacag gaaccaaaat tcttggatgc tcaggtaggt tttagaaaat
     1681 gacattgtat ttccacagaa cctctgccca cccacccata tacttccagt catctccagg
     1741 ttacatgtaa cacctaatcc catgtgaatt ctgtgtaaac agttgctgta ctgctttgtt
     1801 tagggaataa tgataagaag atgctagcat gtgttcagtc cagatggaat ttctcccaaa
     1861 taaatttggt tagcagttga ctg
//
