LOCUS       NM_001170341            1530 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus myeloid leukemia factor 2 (Mlf2), transcript variant
            2, mRNA.
ACCESSION   NM_001170341
VERSION     NM_001170341.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1530)
  AUTHORS   Koopmans,F., van Nierop,P., Andres-Alonso,M., Byrnes,A.,
            Cijsouw,T., Coba,M.P., Cornelisse,L.N., Farrell,R.J.,
            Goldschmidt,H.L., Howrigan,D.P., Hussain,N.K., Imig,C., de
            Jong,A.P.H., Jung,H., Kohansalnodehi,M., Kramarz,B., Lipstein,N.,
            Lovering,R.C., MacGillavry,H., Mariano,V., Mi,H., Ninov,M.,
            Osumi-Sutherland,D., Pielot,R., Smalla,K.H., Tang,H., Tashman,K.,
            Toonen,R.F.G., Verpelli,C., Reig-Viader,R., Watanabe,K., van
            Weering,J., Achsel,T., Ashrafi,G., Asi,N., Brown,T.C., De
            Camilli,P., Feuermann,M., Foulger,R.E., Gaudet,P., Joglekar,A.,
            Kanellopoulos,A., Malenka,R., Nicoll,R.A., Pulido,C., de
            Juan-Sanz,J., Sheng,M., Sudhof,T.C., Tilgner,H.U., Bagni,C.,
            Bayes,A., Biederer,T., Brose,N., Chua,J.J.E., Dieterich,D.C.,
            Gundelfinger,E.D., Hoogenraad,C., Huganir,R.L., Jahn,R.,
            Kaeser,P.S., Kim,E., Kreutz,M.R., McPherson,P.S., Neale,B.M.,
            O'Connor,V., Posthuma,D., Ryan,T.A., Sala,C., Feng,G., Hyman,S.E.,
            Thomas,P.D., Smit,A.B. and Verhage,M.
  TITLE     SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the
            Synapse
  JOURNAL   Neuron 103 (2), 217-234 (2019)
   PUBMED   31171447
REFERENCE   2  (bases 1 to 1530)
  AUTHORS   Choudhury,K.R. and Bhattacharyya,N.P.
  TITLE     Chaperone protein HYPK interacts with the first 17 amino acid
            region of Huntingtin and modulates mutant HTT-mediated aggregation
            and cytotoxicity
  JOURNAL   Biochem Biophys Res Commun 456 (1), 66-73 (2015)
   PUBMED   25446099
REFERENCE   3  (bases 1 to 1530)
  AUTHORS   Sansom,S.N., Griffiths,D.S., Faedo,A., Kleinjan,D.J., Ruan,Y.,
            Smith,J., van Heyningen,V., Rubenstein,J.L. and Livesey,F.J.
  TITLE     The level of the transcription factor Pax6 is essential for
            controlling the balance between neural stem cell self-renewal and
            neurogenesis
  JOURNAL   PLoS Genet 5 (6), e1000511 (2009)
   PUBMED   19521500
REFERENCE   4  (bases 1 to 1530)
  AUTHORS   Molotski,N., Savion,S., Gerchikov,N., Fein,A., Toder,V. and
            Torchinsky,A.
  TITLE     Teratogen-induced distortions in the classical NF-kappaB activation
            pathway: correlation with the ability of embryos to survive
            teratogenic stress
  JOURNAL   Toxicol Appl Pharmacol 229 (2), 197-205 (2008)
   PUBMED   18395765
REFERENCE   5  (bases 1 to 1530)
  AUTHORS   Zhang,D., Harry,G.J., Blackshear,P.J. and Zeldin,D.C.
  TITLE     G-protein pathway suppressor 2 (GPS2) interacts with the regulatory
            factor X4 variant 3 (RFX4_v3) and functions as a transcriptional
            co-activator
  JOURNAL   J Biol Chem 283 (13), 8580-8590 (2008)
   PUBMED   18218630
REFERENCE   6  (bases 1 to 1530)
  AUTHORS   Munton,R.P., Tweedie-Cullen,R., Livingstone-Zatchej,M.,
            Weinandy,F., Waidelich,M., Longo,D., Gehrig,P., Potthast,F.,
            Rutishauser,D., Gerrits,B., Panse,C., Schlapbach,R. and Mansuy,I.M.
  TITLE     Qualitative and quantitative analyses of protein phosphorylation in
            naive and stimulated mouse synaptosomal preparations
  JOURNAL   Mol Cell Proteomics 6 (2), 283-293 (2007)
   PUBMED   17114649
REFERENCE   7  (bases 1 to 1530)
  AUTHORS   Papin,J. and Subramaniam,S.
  TITLE     Bioinformatics and cellular signaling
  JOURNAL   Curr Opin Biotechnol 15 (1), 78-81 (2004)
   PUBMED   15102471
  REMARK    Review article
REFERENCE   8  (bases 1 to 1530)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY286289.1, AK143972.1 and BF464435.1.
            
            Transcript Variant: This variant (2) differs in the 3' UTR compared
            to variant 1. Both variants encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK143972.1, AK141241.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-48                BY286289.1         15-62
            49-1519             AK143972.1         6-1476
            1520-1530           BF464435.1         1-11                c
FEATURES             Location/Qualifiers
     source          1..1530
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 59.17 cM"
     gene            1..1530
                     /gene="Mlf2"
                     /note="myeloid leukemia factor 2"
                     /db_xref="GeneID:30853"
                     /db_xref="MGI:MGI:1353554"
     exon            1..199
                     /gene="Mlf2"
                     /inference="alignment:Splign:2.1.0"
     exon            200..277
                     /gene="Mlf2"
                     /inference="alignment:Splign:2.1.0"
     exon            278..404
                     /gene="Mlf2"
                     /inference="alignment:Splign:2.1.0"
     exon            405..440
                     /gene="Mlf2"
                     /inference="alignment:Splign:2.1.0"
     exon            441..494
                     /gene="Mlf2"
                     /inference="alignment:Splign:2.1.0"
     exon            495..623
                     /gene="Mlf2"
                     /inference="alignment:Splign:2.1.0"
     exon            624..783
                     /gene="Mlf2"
                     /inference="alignment:Splign:2.1.0"
     exon            784..996
                     /gene="Mlf2"
                     /inference="alignment:Splign:2.1.0"
     exon            997..1523
                     /gene="Mlf2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1498..1503
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mlf2"
                     /note="hexamer: AATAAA"
     polyA_site      1518
                     /gene="Mlf2"
                     /note="major polyA site"
ORIGIN      
        1 ttccgttcgg gcctgaccga agatcggctt ctcgggccga gggcgggggt acggaggtgg
       61 caggcgaagg caggaggcgg tgcgggaggc gagaagctgc cgcgcggacc aatccttgcg
      121 tcccgggccg cgaccctgct cctgcagcgc cccgaggaga ggccggccgg atgggccgct
      181 gagccggagt cggggaccgt gtggagcccc ctggagctga gatcacgatg ttccgcttca
      241 tgagggacgt ggagcctgag gatcccatgt tcctgatgga ccccttcgca attcaccgtc
      301 agcacatgag ccgcatgttg tcaggcggct ttggatatag ccccttcctg agcatcacag
      361 atggtaacat gccagcaacc aggcctgcca gccgcaggat gcaggctggg gctgtctctc
      421 ccttcgggat gttgggaatg tccggcggtt tcatggacat gtttgggatg atgaacgaca
      481 tgatcgggaa catggagcac atggctgcag ggggcaactg ccagaccttc tcctcctcca
      541 ctgttatctc ctactccaac actggggacg gcgcgcccaa ggtttaccag gagacgtcgg
      601 agatgcgctc tgccccaggc gggatccggg agacacggag gactgtccgg gactcagaca
      661 gtggtctaga gcagatgtcc attgggcatc acattcggga tagggctcac atcctccagc
      721 gctcccgaaa ccaccgcaca ggggaccagg aagagcggca ggactacatc aacctggatg
      781 aaagtgaggc agcagcattt gatgatgaat ggagaaggga gacatcccga tacagacagc
      841 agcgtcctct ggaatttcga cggcatgagg catctgtggg tggggggcga agggctgagg
      901 ggcctccccg cctggcgatc cagggacctg aggactcccc ctcccgacag tcccgtcgtt
      961 atgactggtg aaggccccag gctctcagct tctcatgtgc aggctgagcg gctgagtaac
     1021 catccttgaa atgactgtcc tttccaacct ctatcccaat ttaatattaa attaacaggc
     1081 aagctggccc cgcctctccc tgggtctcag ggagagcctt ctactgcccc ccttacctac
     1141 gtttccatct tcacccctca ctgcgtgtcc cacccatcct gtatccacta acttgagttc
     1201 tcatgttgct gctccatctc caagccgcct catcttcccg agcccctgcc acgcatcgaa
     1261 gggttttggg gaaagctctg ggtttaggga tctccgtccc tcagctcccc tgacccttgc
     1321 ccacctcttc ctcagagccc cactgcaggt gccatggtcc tataagggct gtggagaaag
     1381 tggactagtt ccaattcttt gtcccttccc ccacccatca cagaaacact ttcctttacc
     1441 cttctctgcc tttataaaaa ctaatgattt gtgcaacttg taactaggtg tttatggaat
     1501 aaaggagaat ggaaaaaagt gaaaaaaaaa
//
