LOCUS       NM_001164370            1454 bp    mRNA    linear   ROD 22-DEC-2022
DEFINITION  Mus musculus mirror-image polydactyly 1 (Mipol1), mRNA.
ACCESSION   NM_001164370
VERSION     NM_001164370.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1454)
  AUTHORS   Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK,
            Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L,
            Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre
            JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A,
            Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ,
            Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall
            S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA,
            Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR,
            Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana
            S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, MacArthur DG,
            Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC,
            Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL,
            de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown
            SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bucan M and Murray
            SA.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. PMID: 29144450]
REFERENCE   2  (bases 1 to 1454)
  AUTHORS   Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H,
            Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T,
            Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P,
            Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ,
            Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD,
            Flicek P, Skarnes WC, Mallon AM and Parkinson H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   3  (bases 1 to 1454)
  AUTHORS   Cheung AK, Lung HL, Ko JM, Cheng Y, Stanbridge EJ, Zabarovsky ER,
            Nicholls JM, Chua D, Tsao SW, Guan XY and Lung ML.
  TITLE     Chromosome 14 transfer and functional studies identify a candidate
            tumor suppressor gene, mirror image polydactyly 1, in
            nasopharyngeal carcinoma
  JOURNAL   Proc Natl Acad Sci U S A 106 (34), 14478-14483 (2009)
   PUBMED   19667180
REFERENCE   4  (bases 1 to 1454)
  AUTHORS   Lin Q, Donahue SL, Moore-Jarrett T, Cao S, Osipovich AB and Ruley
            HE.
  TITLE     Mutagenesis of diploid mammalian genes by gene entrapment
  JOURNAL   Nucleic Acids Res 34 (20), e139 (2006)
   PUBMED   17062627
REFERENCE   5  (bases 1 to 1454)
  AUTHORS   Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber
            G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong
            WH and Cepko CL.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   6  (bases 1 to 1454)
  AUTHORS   Kondoh S, Sugawara H, Harada N, Matsumoto N, Ohashi H, Sato M,
            Kantaputra PN, Ogino T, Tomita H, Ohta T, Kishino T, Fukushima Y,
            Niikawa N and Yoshiura K.
  TITLE     A novel gene is disrupted at a 14q13 breakpoint of t(2;14) in a
            patient with mirror-image polydactyly of hands and feet
  JOURNAL   J Hum Genet 47 (3), 136-139 (2002)
   PUBMED   11954550
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124486.4 and AC122307.4.
            
            [WARNING] On Jun 14, 2023 this sequence was replaced by
            NM_001164370.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK077915.1, SRR10662773.2347114.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-187               AC124486.4         153468-153654       c
            188-394             AC124486.4         80528-80734         c
            395-521             AC124486.4         77942-78068         c
            522-627             AC124486.4         76615-76720         c
            628-757             AC124486.4         58426-58555         c
            758-791             AC124486.4         52050-52083         c
            792-962             AC124486.4         51620-51790         c
            963-1070            AC124486.4         19845-19952         c
            1071-1165           AC122307.4         78175-78269
            1166-1454           AC122307.4         120812-121100
FEATURES             Location/Qualifiers
     source          1..1454
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 24.7 cM"
     gene            1..1454
                     /gene="Mipol1"
                     /gene_synonym="1700081O04Rik; 6030439O22Rik; D12Ertd19e"
                     /note="mirror-image polydactyly 1"
                     /db_xref="GeneID:73490"
                     /db_xref="MGI:MGI:1920740"
     exon            1..187
                     /gene="Mipol1"
                     /gene_synonym="1700081O04Rik; 6030439O22Rik; D12Ertd19e"
                     /inference="alignment:Splign:2.1.0"
     exon            188..394
                     /gene="Mipol1"
                     /gene_synonym="1700081O04Rik; 6030439O22Rik; D12Ertd19e"
                     /inference="alignment:Splign:2.1.0"
     CDS             261..1400
                     /gene="Mipol1"
                     /gene_synonym="1700081O04Rik; 6030439O22Rik; D12Ertd19e"
                     /note="mirror-image polydactyly gene 1 homolog"
                     /codon_start=1
                     /product="mirror-image polydactyly gene 1 protein homolog"
                     /protein_id="NP_001157842.1"
                     /db_xref="CCDS:CCDS49070.1"
                     /db_xref="GeneID:73490"
                     /db_xref="MGI:MGI:1920740"
                     /translation="MNSEQSIRELGNEVPSEDLELPGRKPSNFQVLQPCRDEGASAEC
                     SIVECGKNYEPVISHQVIPDLNKETSVAYLQKELEILRASNTKLQEKLAKEDKEKRRL
                     KLKLELQEKAAEADIAERTAALVEEVYFAQRERDEAIMCRLQLALKERDEAIAHVKHM
                     EMSLKMLENINPEENDMTLQELLNRINNADTGIAIQKNGAVIVDTIYKTKECRKRITA
                     EEMSAVLEERDAALSQCKRLHQELHRLKEQNQTSANNTRRPTAENNQERALKAKLLSM
                     QQARETAVEQYKRLEEEIQTLRVYYSLHKSLSQEESLKDQFNHALSTYEEALKNRESV
                     VSITQQQNEELATQLQQALTEHSHMELQLQCAVEASQAANEKVQK"
     exon            395..521
                     /gene="Mipol1"
                     /gene_synonym="1700081O04Rik; 6030439O22Rik; D12Ertd19e"
                     /inference="alignment:Splign:2.1.0"
     exon            522..627
                     /gene="Mipol1"
                     /gene_synonym="1700081O04Rik; 6030439O22Rik; D12Ertd19e"
                     /inference="alignment:Splign:2.1.0"
     exon            628..757
                     /gene="Mipol1"
                     /gene_synonym="1700081O04Rik; 6030439O22Rik; D12Ertd19e"
                     /inference="alignment:Splign:2.1.0"
     exon            758..791
                     /gene="Mipol1"
                     /gene_synonym="1700081O04Rik; 6030439O22Rik; D12Ertd19e"
                     /inference="alignment:Splign:2.1.0"
     exon            792..962
                     /gene="Mipol1"
                     /gene_synonym="1700081O04Rik; 6030439O22Rik; D12Ertd19e"
                     /inference="alignment:Splign:2.1.0"
     exon            963..1070
                     /gene="Mipol1"
                     /gene_synonym="1700081O04Rik; 6030439O22Rik; D12Ertd19e"
                     /inference="alignment:Splign:2.1.0"
     exon            1071..1165
                     /gene="Mipol1"
                     /gene_synonym="1700081O04Rik; 6030439O22Rik; D12Ertd19e"
                     /inference="alignment:Splign:2.1.0"
     exon            1166..1454
                     /gene="Mipol1"
                     /gene_synonym="1700081O04Rik; 6030439O22Rik; D12Ertd19e"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgctcgctg cgcgcagcct cgtccccgcg tgctctcgcg cgcttcctct cgcccgctct
       61 gctctttttg gttactcagg ggcacgcgca gcgtttcgcg cgacgattgg ctgcctcggt
      121 ggcggcgcca caggaccggg caactacgcg agcggagtgg gcgcttaagg atcccgcggc
      181 tcctcagata tagccatatt tgtcttgcac aagagagctc agtgggaagt gaacgcgcac
      241 cagtagatga gcagctgact atgaattctg agcagagcat acgcgaatta ggcaatgaag
      301 tcccatctga ggaccttgaa ctaccaggaa gaaaacccag caattttcag gtcctccaac
      361 cttgtcggga tgaaggggca tctgcagagt gcagtattgt ggaatgtggg aagaattacg
      421 aacctgtgat ttctcatcaa gttatcccag acttaaataa agagacatca gtagcatatc
      481 ttcaaaaaga attggaaatt ctcagagcaa gcaatacaaa gcttcaagaa aaattggcta
      541 aggaagataa agagaagaga agactgaagc ttaagttgga actccaagag aaagccgcgg
      601 aggctgacat tgcggaaagg actgcagctt tggttgaaga agtgtatttt gcacagcgag
      661 aacgtgatga agctattatg tgccgactgc agttagccct caaggagaga gacgaagcca
      721 ttgcacatgt gaaacatatg gaaatgtcac taaaaatgct agaaaatatt aaccctgaag
      781 aaaatgacat gacattacag gaattactga acagaataaa caatgcagac actgggatag
      841 ctattcagaa gaatggagct gtgattgtgg atacaatcta caagaccaag gaatgtagga
      901 agagaataac cgcagaagaa atgagtgcag tcctagagga gcgggatgcg gctttgtctc
      961 agtgcaaacg gctgcaccag gagcttcatc gtctgaaaga gcagaaccag acttcagcaa
     1021 acaacacgag acgtccgacg gctgaaaaca atcaggaacg tgctctgaag gcaaaattat
     1081 tgtcaatgca gcaagccaga gaaactgcag ttgaacagta caaaaggctg gaagaagaaa
     1141 tacagacatt acgagtttac tacagcttgc acaaatcatt atctcaagaa gaaagcctga
     1201 aggatcagtt taaccatgcc cttagtacct atgaagaagc cttaaaaaac agagagagcg
     1261 ttgtctccat cactcagcaa cagaatgaag aactggccac ccaacttcag caggctctca
     1321 ctgagcactc tcacatggaa ttacagcttc agtgtgctgt ggaggcctcc caggcagcca
     1381 acgaaaaggt tcagaagtaa gtaaccgatc cagccctgac cctaaaggca tgaaacgtta
     1441 gagaaaagaa aagg
//
