LOCUS       NM_001142781            4270 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus MINDY lysine 48 deubiquitinase 4 (Mindy4), transcript
            variant 1, mRNA.
ACCESSION   NM_001142781
VERSION     NM_001142781.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4270)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4270)
  AUTHORS   McClintock,T.S., Glasser,C.E., Bose,S.C. and Bergman,D.A.
  TITLE     Tissue expression patterns identify mouse cilia genes
  JOURNAL   Physiol Genomics 32 (2), 198-206 (2008)
   PUBMED   17971504
  REMARK    GeneRIF: C330043M08Rik is most abundantly expressed in tissues rich
            in highly ciliated cells, such as olfactory sensory neurons, and is
            predicted to be important to cilia.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK082855.1 and AK142385.1.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK142385.1, AK161304.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-82                AK082855.1         2-83
            83-4270             AK142385.1         1-4188
FEATURES             Location/Qualifiers
     source          1..4270
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 27.38 cM"
     gene            1..4270
                     /gene="Mindy4"
                     /gene_synonym="C330043M08Rik; Fam188b; Gm1406"
                     /note="MINDY lysine 48 deubiquitinase 4"
                     /db_xref="GeneID:330323"
                     /db_xref="MGI:MGI:3583959"
     exon            1..187
                     /gene="Mindy4"
                     /gene_synonym="C330043M08Rik; Fam188b; Gm1406"
                     /inference="alignment:Splign:2.1.0"
     exon            188..307
                     /gene="Mindy4"
                     /gene_synonym="C330043M08Rik; Fam188b; Gm1406"
                     /inference="alignment:Splign:2.1.0"
     exon            308..543
                     /gene="Mindy4"
                     /gene_synonym="C330043M08Rik; Fam188b; Gm1406"
                     /inference="alignment:Splign:2.1.0"
     exon            544..790
                     /gene="Mindy4"
                     /gene_synonym="C330043M08Rik; Fam188b; Gm1406"
                     /inference="alignment:Splign:2.1.0"
     exon            791..1161
                     /gene="Mindy4"
                     /gene_synonym="C330043M08Rik; Fam188b; Gm1406"
                     /inference="alignment:Splign:2.1.0"
     exon            1162..1217
                     /gene="Mindy4"
                     /gene_synonym="C330043M08Rik; Fam188b; Gm1406"
                     /inference="alignment:Splign:2.1.0"
     exon            1218..1324
                     /gene="Mindy4"
                     /gene_synonym="C330043M08Rik; Fam188b; Gm1406"
                     /inference="alignment:Splign:2.1.0"
     exon            1325..1441
                     /gene="Mindy4"
                     /gene_synonym="C330043M08Rik; Fam188b; Gm1406"
                     /inference="alignment:Splign:2.1.0"
     exon            1442..1530
                     /gene="Mindy4"
                     /gene_synonym="C330043M08Rik; Fam188b; Gm1406"
                     /inference="alignment:Splign:2.1.0"
     exon            1531..1632
                     /gene="Mindy4"
                     /gene_synonym="C330043M08Rik; Fam188b; Gm1406"
                     /inference="alignment:Splign:2.1.0"
     exon            1633..1696
                     /gene="Mindy4"
                     /gene_synonym="C330043M08Rik; Fam188b; Gm1406"
                     /inference="alignment:Splign:2.1.0"
     exon            1697..1762
                     /gene="Mindy4"
                     /gene_synonym="C330043M08Rik; Fam188b; Gm1406"
                     /inference="alignment:Splign:2.1.0"
     exon            1763..1830
                     /gene="Mindy4"
                     /gene_synonym="C330043M08Rik; Fam188b; Gm1406"
                     /inference="alignment:Splign:2.1.0"
     exon            1831..1894
                     /gene="Mindy4"
                     /gene_synonym="C330043M08Rik; Fam188b; Gm1406"
                     /inference="alignment:Splign:2.1.0"
     exon            1895..2056
                     /gene="Mindy4"
                     /gene_synonym="C330043M08Rik; Fam188b; Gm1406"
                     /inference="alignment:Splign:2.1.0"
     exon            2057..2237
                     /gene="Mindy4"
                     /gene_synonym="C330043M08Rik; Fam188b; Gm1406"
                     /inference="alignment:Splign:2.1.0"
     exon            2238..2310
                     /gene="Mindy4"
                     /gene_synonym="C330043M08Rik; Fam188b; Gm1406"
                     /inference="alignment:Splign:2.1.0"
     exon            2311..4270
                     /gene="Mindy4"
                     /gene_synonym="C330043M08Rik; Fam188b; Gm1406"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2694..2699
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mindy4"
                     /gene_synonym="C330043M08Rik; Fam188b; Gm1406"
                     /note="hexamer: CATAAA"
     polyA_site      2728
                     /gene="Mindy4"
                     /gene_synonym="C330043M08Rik; Fam188b; Gm1406"
                     /note="major polyA site"
ORIGIN      
        1 ggggaggagt tcttcctggc gcggatgcca ccgtcgccac ggcaacgccg ctttactggg
       61 cccaacggat taaggggcct ggggctgcag gcggccgcgt ggcctcgtgg gcagcgctag
      121 cagcatggac agtctgtacg tggaggaggt ggccgcctcc ctggtcaggg agtttcttag
      181 cagaaagggt ttgaacaaga catttgtgac catggaccag gagcgccccc gctgtgagct
      241 tagcatcaac agcagaaatg atctccgcaa agttctgcat ctggagtttc tctacaagga
      301 gaacaaggca aaagaaaagc ctctaagaac aaacctggag ctcattacca ggtactttct
      361 ggataatgtt ggaaatacag ataacagtga aagtcaagaa gtcccaatcc ctgcaatccc
      421 tgttccaaag aaaaacaaca agttgccttt gagacactca gagaccacat tggtgaatat
      481 atacgacctt tcagatgaag atacgggaag acggacatca tggtcagaag caggcaaagc
      541 caggcatgac agtctggatg gggacatact tggtaatttc gtatcatcca aaaaaccctc
      601 acacaaaagt aaggctgcac acgtggacct gggtgacagc ctcccgttgg ttcctgcgtg
      661 ggagaaggtg gaccagcttc actcatcaga gcccggtata gatgtgaaga agacaatgga
      721 gaggaccagg cctaagtctg gcctgattgt ccgaggcatg atggctgggc ctgtcgccag
      781 ctcccctcag gactctttcc gcaaacgctc tctgagaagg tcctcagctc tgagcaggaa
      841 gctccaaacc ccagaggaga tccagcagca gtctgagcct tttgtccaca ccccagccta
      901 tctgggtcca caggaggtcc ccgattccag cagtgactcc gtctccagaa gccctctggg
      961 ccagctgaat gaactgtcta tagagaagcc aaatgtcact tctagcagcc aagggctgtc
     1021 ccagagggac agacccaggc taagaagtgt ttcagaggac agcccactgg ggtacagcca
     1081 cacagagggg aattccagga tggcccagga ccagctggaa agagcgttca agcgtcaggg
     1141 cgtccagcct ccatctctca ggaaaaatca gttggtgtct gacaggacgg atgataagcc
     1201 agatgccctg cagctagagg atgttgagga tgagttgata aaggaagaca ttgtcttgtt
     1261 tccacctcca tcaatgctca agcttcagac tgtgtcaaag ccaattgacc tctcactggc
     1321 taaggagata aagacccttc tgtttggctc taccttttgc tgcttcagtg aagaatggaa
     1381 acttcagaac ttttccttca atgacattgc ctcgttaaaa tacggcattg tgcagaacaa
     1441 gggtggtccc tgtggggttc tggcagctgt tcaaggctgt gtgcttcaga aactcctgtt
     1501 tgaaggagat aacagaacca actctaatct ccggctgcag ccctcagatg cccagaggac
     1561 tcgctgcctt gccctggcca ttgccgacat cctgtggcga gctggaggca aagaacaagc
     1621 cgtggttgca ctggcttcag gaacaccgca cttcagtcca acagggaaat acaaagcaga
     1681 tggagtctta gaaacactca cactgtatag tttgaccagc tcagaggacc tggtgacttt
     1741 tatccagcag agtgttcatc agtttgaagc tggaccctat ggttgcatcc tgctcacctt
     1801 gtctgctatc ctgtccaggt ccctggagct tgtccggcag gactttgatg tccccaccag
     1861 ccatctcatt ggagctcatg gatactgcac acaggaactt gtcaatcttc tcctgactgg
     1921 gagagccgtg tctaatgttt tcaatgatgt agtggagctg gactcaggtg atgggaacat
     1981 cacgctcctc cgaggcatcg aggcacgcag tgacatcggc ttcttatctc tctttgaaca
     2041 ctacaatgtg tgccaggttg gctgcttcct aaagacgcca aggttcccca tctgggtggt
     2101 ctgcagtgag agccacttca gcatcctctt cagcctacag ccagagctct tgtgcgactg
     2161 gaggtctgag cggctttttg acctgtatta ctatgacggc ttggccaacc agcaggagga
     2221 gatacgtctg actgttgata ccaccaagac cgccccagcg gacagctgca gtgaccttgt
     2281 ccctcctctt gagctctgta tcagaaccaa gtggaagggg gcatctgtaa actggaacgg
     2341 ctcagacccc atcctgtgac ccttggatac atggagttct atggcttcag cactcatcac
     2401 tgggatgacc ccgggacccc aggtcttagg gtcaagtctc ttagaggagt caccctgcct
     2461 gagtttgcat gtccacagag gcatgctcag tcttccagtt ccttccatga agggccatgg
     2521 cagggtcctg ttgagattcc ctcctggcct agatgtgcct gccaaagaca ggaaggaggg
     2581 aggccaccag agactctact gcctttcgtt tgcatccttc ctgaataacc ctctctccaa
     2641 ggcctctggt gtcactggct ttggggaccc tggagtcttg ttactgcagc ttccataaag
     2701 caaaagtcaa gcctatgacc agggcaaatt tggactgtgg ttggttcatt ggtgtgagtg
     2761 gaacccgggt ctgctatcat catggctaag atgggacagg gaggtggagg tccaggattc
     2821 cggtgtgctg agtatctcct agccaagagg tgaggccaag cccagccctt tgtcccagag
     2881 atgcccttgt ctgggtggag cagcgtggtc taagatacaa gctaccaaga gcagccaaag
     2941 gtctggagag cccacttcag ggaagacctg gttttcttgt gaggccatat gaggctgggg
     3001 tgggcctaga aggaggctgg gatgggcagg gctagaaagg tacccaggaa atgacttctt
     3061 gcccaggtga gcaaaaaaga tggggacaag cagagggatc cagtgtcaac ttccctgtgg
     3121 ctgtggggag aactgactgc catcatgggt gggcaggact ttggaagtgc tcacattgca
     3181 gaataaggag agattagagg gggatggtat gctctgagtt tcacttacca catggcgtat
     3241 atccactggc tttcgtcatg gaaagtgata aagcaggagt gggtcactag ggaagaactc
     3301 ctggaggtac tggatggttc agagccagag tctagggctg cttgtagcag ttcacaccag
     3361 gaacctcaga ctgaagctcc agacctcaga gtccctgtca tatggctgtc caggaagaaa
     3421 tgaggaccca aataacggta aagctttcag gtgcctccac cctagcccgg cagcccatct
     3481 ttggcctcca tgtgtcccca tagggtttag gagcatagct gctctagact gtgtcccctg
     3541 taattagaag tccccttgct gtaaggagaa acccctccgt taaggagtta ggcgtttggt
     3601 ggggacaact acggagcttg tcttatgttc ccgtgggtag ggcacacact gtgtcccaac
     3661 tgcagacctt cggagaggca gggaggagtc aattatgcca tagaagcaga gggcgggaag
     3721 ggctgtgtcc tgcactaggc tcccacgggg cttgctgtgt aaactttagt ggccattcac
     3781 agcaggttcc cagtagaaat gcttcctata tctccttgaa atgtttatgc atttgttttc
     3841 cttggccgca gatgggcagc tgcagagtgc ctggctgagg aagctggttt ccctgcaatg
     3901 gccttgttta tcgggcctgg ggaggaaaag tatctcttca atgaaaccca cttagtctcc
     3961 ttgccagggg ctctttggca gggctagagg aaaacaaaca attcccagca ttactgcaga
     4021 aggttgaccc aacaaagcac agagcttgct cttctaagag gccagattgc agacacacaa
     4081 gcactatgcc tcggagtgga aggtgggcag agctgggtac aaccactccc aggcttgaag
     4141 ccttagcatt ctcagtaaca ctcccaggac caaaacacct catcacaagt gtcattgttc
     4201 tctagggtgc cgaggtagag gactgcctca cagccctctc ccggactgta ttaaaaccat
     4261 tcgtgctcac
//
