LOCUS       NM_153509               4250 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus membrane integral NOTCH2 associated receptor 1
            (Minar1), mRNA.
ACCESSION   NM_153509
VERSION     NM_153509.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4250)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4250)
  AUTHORS   Quina,L.A., Wang,S., Ng,L. and Turner,E.E.
  TITLE     Brn3a and Nurr1 mediate a gene regulatory pathway for habenula
            development
  JOURNAL   J Neurosci 29 (45), 14309-14322 (2009)
   PUBMED   19906978
REFERENCE   3  (bases 1 to 4250)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC121793.3.
            
            On Nov 17, 2006 this sequence version replaced NM_153509.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF529169.1, AK173089.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-370               AC121793.3         21088-21457
            371-2723            AC121793.3         40680-43032
            2724-2978           AC121793.3         47384-47638
            2979-4250           AC121793.3         52774-54045
FEATURES             Location/Qualifiers
     source          1..4250
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 47.24 cM"
     gene            1..4250
                     /gene="Minar1"
                     /gene_synonym="DD1; Kiaa1024"
                     /note="membrane integral NOTCH2 associated receptor 1"
                     /db_xref="GeneID:209743"
                     /db_xref="MGI:MGI:2667167"
     exon            1..370
                     /gene="Minar1"
                     /gene_synonym="DD1; Kiaa1024"
                     /inference="alignment:Splign:2.1.0"
     exon            371..2723
                     /gene="Minar1"
                     /gene_synonym="DD1; Kiaa1024"
                     /inference="alignment:Splign:2.1.0"
     CDS             423..3176
                     /gene="Minar1"
                     /gene_synonym="DD1; Kiaa1024"
                     /note="ubiquitination and mTOR signaling protein"
                     /codon_start=1
                     /product="major intrinsically disordered Notch2-binding
                     receptor 1"
                     /protein_id="NP_705729.1"
                     /db_xref="CCDS:CCDS23395.1"
                     /db_xref="GeneID:209743"
                     /db_xref="MGI:MGI:2667167"
                     /translation="MEANQEASLFLVKILEELDSKQNTVSYQDLCKSLCAQFDLSQLA
                     KLRSVLFYTACLDPNFPATLFKDKMKCSVNNQQSKKIMVAADIVTIFNLIQMNGGTAK
                     EKLPMSCHKVRKKEASFESCRSDTEVCSPTVCEPLNCELSERPFSRGYPTRQSSKCRK
                     MDCKECPQFVPASEPNFLLGVSKEVKNRAASLDRLQALSPYSVASPQPCEMQRTYFPM
                     NIENEPMSDQDSLPISQGIKETFISSEEPFVVQSCVQKRNIFKEDFHNLMTVSPSLVG
                     TTNKAEEGHGEPQSQKELHKPPFFNHSFEMPYHNQYLNPVYSPIPDKRRAKHESLDDL
                     QASTYFGPTPVMGTQDTRRCPGRSSKQTPWPAKSWSLNTEEVPDFERSFFNRNPSEEK
                     LRYPNSGSQTPNFSGPDRHPVYLVPKDQQKVLPAGYAVKPNGLKSKEISSPVDLEKHE
                     AVKKFKDKSISCTSGQHSSDTSSVGTQTEQHVLDPPKCKDLCTSGQAKYGDRHAMKQS
                     DDDSEIVSDDISDIFRFLDDMSISGSTGVIQSSCYNSTGSLSQLHKSDCDSSPEHHLA
                     KITNGVSSGKGDKCNRPENVHHSEEELKSSVCKLVLRIGEIERKLESLSGVREEISQV
                     LGKLNKLDQKIQQPEKVNVQIDLNSLTSEAPSDDSASPRVFRAHSGSHGPKLENSPDW
                     CCSDASGSNSESLRVKALKKSLFTRPSSRSLTEENSATESKIASISNSPRDWRTITYT
                     NRMSLNEEEIKDAGPANNKDWHRKSKEADRQYDIPPQHRLPKQPKDGFLVEQVFSPHP
                     YPTSLKGHMKSNPLYTDMRLTELAEVKRGQPSWTIEEYARNSGDKGKLTALDLQTQES
                     LNPNNLEYWMEDIYTPGYDSLLKRKEAEFRRAKVCKIAALITAAACTVILVIVVPICT
                     MKS"
     exon            2724..2978
                     /gene="Minar1"
                     /gene_synonym="DD1; Kiaa1024"
                     /inference="alignment:Splign:2.1.0"
     exon            2979..4250
                     /gene="Minar1"
                     /gene_synonym="DD1; Kiaa1024"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3443..3448
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Minar1"
                     /gene_synonym="DD1; Kiaa1024"
                     /note="hexamer: AATAAA"
     polyA_site      3463
                     /gene="Minar1"
                     /gene_synonym="DD1; Kiaa1024"
                     /note="major polyA site"
ORIGIN      
        1 caagaccgtg atgtggtgac actggctgag cctcagaaac cgagattggg gctgatccgg
       61 actctgaggc cgcatcctcc agccgctgag agccccagca tcatgcaagt gggcagtggc
      121 tgccgactgc ccaggaaagc ccgggtgcga ccctagtctg cagatccaga cctcgtgctg
      181 tgggggctga agttaaccta cgccaggggt gttgccccaa gtgcaaagcc tgggctgccc
      241 tggagcctag gattcttttg cctagggaac cttcgggaag ctctgcgttg gaggccctgt
      301 ggaccaccac ctcagagcca cgcaagagct gcggaggacc ggggacggag agctggagca
      361 gcccccagag gatagaactg gctggtgctg cagtgtagtc agtaagcttg cacatctaaa
      421 tcatggaggc caatcaggaa gcttccctct ttttggtgaa gatcttagaa gaactggaca
      481 gtaaacaaaa tactgtttcc tatcaagacc tgtgcaagtc actctgtgcc cagtttgatc
      541 tgtctcagct tgccaaactg agaagtgtgc ttttctatac agcatgcctc gatcccaact
      601 ttccagcaac tttattcaaa gacaagatga aatgctctgt aaataatcag cagtcaaaga
      661 aaatcatggt ggcagcagat atcgtaacaa tcttcaacct gatccagatg aatgggggca
      721 ctgccaagga gaagctgccc atgagttgcc acaaggtgcg caagaaggaa gcatcctttg
      781 agtcttgccg gtccgacacc gaggtgtgca gcccgacagt ttgtgagcct ctgaactgtg
      841 agctgagtga gagacccttc agccgaggct accccaccag gcagtcatcc aaatgccgga
      901 agatggactg taaggaatgc ccacagtttg tccctgcctc tgagcccaac ttcctgttgg
      961 gtgttagcaa agaggtgaaa aatcgggcag cctctctgga taggctgcaa gccctgtccc
     1021 cctattctgt ggccagccct cagccctgtg agatgcagag gacctatttc cccatgaata
     1081 ttgagaacga gcccatgtca gatcaggact ctctgcccat cagccaaggc atcaaagaga
     1141 ccttcatctc cagtgaggaa ccgtttgtgg ttcagtcctg tgttcagaaa aggaacatct
     1201 tcaaagaaga cttccacaat ctcatgactg tatcccccag tttggttggt acaactaaca
     1261 aagcagaaga gggtcatggg gagccccaga gtcagaagga gctccacaag ccacccttct
     1321 tcaaccacag ctttgagatg ccttaccaca accaatacct gaatccggtg tattccccca
     1381 tccctgacaa aaggcgggcg aagcatgaaa gcttagatga ccttcaagcc tctacctatt
     1441 ttggacccac tccagtgatg ggaacacaag ataccaggcg ctgtccaggg aggtccagta
     1501 aacagactcc atggcccgcc aaaagctgga gcctaaacac ggaggaagtg cctgatttcg
     1561 aacgctcctt tttcaataga aatccctctg aagagaagct acgctatcca aattctggca
     1621 gccagactcc caatttctca ggcccagaca ggcatccagt ttacttggtg ccaaaggatc
     1681 aacagaaggt tctccctgct ggctatgcag tgaaaccaaa tggactcaaa tcgaaagaga
     1741 tctcgtcccc tgttgaccta gagaagcacg aagcagtcaa gaagtttaaa gacaaaagca
     1801 tcagctgcac cagtgggcag cacagctcag acaccagtag tgtgggtacc cagacagagc
     1861 agcatgtgct ggatcccccc aaatgcaaag atttgtgtac ttcgggtcag gccaagtacg
     1921 gtgacaggca tgccatgaag cagtcggacg atgactcaga aatcgtcagc gacgacatca
     1981 gtgacatttt ccggtttctc gatgacatga gcatcagcgg ctccacagga gtgatacagt
     2041 catcctgcta caacagcacc ggctccttgt ctcagcttca taagtcagac tgtgatagtt
     2101 cgccagagca ccacctcgcc aaaatcacca atggggtctc cagcggcaag ggggacaagt
     2161 gtaaccggcc tgaaaacgtc catcactccg aggaagagtt gaagagtagc gtgtgcaaac
     2221 tggttctcag gattggtgag atagagcgga agctggaatc gctgtctggg gtccgagagg
     2281 aaatctccca ggtccttggg aaactcaata aactggatca gaaaatacag cagccggaga
     2341 aagtgaatgt gcagattgac ctgaactcct tgacgagtga ggcaccttct gatgacagcg
     2401 cctctccgag ggtcttccgt gcacacagtg gctcccacgg acctaagctg gagaacagtc
     2461 ctgactggtg ctgctcagat gccagtggaa gtaacagtga aagcctgcgt gtcaaggcct
     2521 taaagaaaag cctctttacc aggccatctt ccaggtccct gactgaggag aacagtgcca
     2581 cagagtctaa aattgccagc atctcgaact ctcccagaga ctggcgaacc atcacataca
     2641 ccaaccggat gagcctcaac gaggaggaga taaaagatgc aggcccagcc aataacaaag
     2701 attggcatcg gaaatctaag gaggcagaca ggcagtatga catcccccca cagcacagat
     2761 tgcccaagca gcccaaagat ggcttcctgg tggagcaggt gttcagccct catccttacc
     2821 ccacctccct caagggccac atgaagagca accccctgta tacagacatg cggctgactg
     2881 aactagctga ggtgaagcgg ggccagcctt cttggaccat agaggaatat gctcggaact
     2941 ccggtgacaa aggcaagctg acagctctgg acctgcagac ccaagaatct ttaaacccaa
     3001 acaacttaga gtactggatg gaagatattt atactccagg ctatgattca ttactaaaac
     3061 ggaaagaagc tgaattcaga cgagccaagg tttgcaagat cgctgctctt atcactgctg
     3121 ctgcatgcac ggtcattctt gtcattgttg tgccaatctg cacgatgaag tcctgaacct
     3181 gtggactcag cattacatgc agctcctgac tcccaaagtc tttctctgta atttcaaaag
     3241 ctggccccac tgtggctaca gtctgctgga atagagacaa aatcctggat gcgtttctac
     3301 agtgccgaag gtcatctcca gagagtatat actctggaaa gacatctgcc tagctgttaa
     3361 gctttgacat agctacactc tgaatatatt tccaaaagta cactatcctt ttccacataa
     3421 ggaatgccat ggattgtcag taaataaaag ttggattctt tcatttggat ggtgattcgt
     3481 ggtgggcatt aagttataca gaacagatcc aatacctgct ctttgaagga gctgactgac
     3541 gttgacacaa tgattaaaaa aaaaaagaga aagagcaaaa gcaaaggggt gcgatctctt
     3601 tccttaacat gctacgtttg ttgctggcga tgtgactgga tgtgtgtcca caagaacgtg
     3661 gcttctcctc ggacttttat taagggctac tgacttccat cttgcccttc tgtcattgtc
     3721 tgtagaacat ctgaattgtt gcagctcctg aaagcagctt tctgaatttc tttggcccag
     3781 gcaagaggga gctgtacttc caggccaagc atgatgatac agtatccttt ttgtagagtg
     3841 ggtcaagaca ctcaggatag ggaatctgct tgttgtcccc aaaatgatgt ggggaagctt
     3901 gccttgccgg ttggggtatg ctcaacatct gaagctcaca gccaccctaa aggatctctg
     3961 gttatagctc tggcatgtgg ctccgttcct tgattttcta actcttggtg gtccctgatg
     4021 ctctattctg aagagtttgg aacttgtcct tgtgccttga agagcagaga caatggtgac
     4081 aatttagcat tctaactata aaccatggtt tccgcccacc actggtacca accatttatg
     4141 tggctttaaa aaagattttg aatgcttatt caatagataa aggtaccaag gtcttttcaa
     4201 ttacaacatt tactccagtt ttaaatattt gtcagcagtg caaaaaaaaa
//
