LOCUS       NM_001025365            1830 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus migration and invasion inhibitory protein (Miip),
            transcript variant 2, mRNA.
ACCESSION   NM_001025365
VERSION     NM_001025365.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1830)
  AUTHORS   Ko,M.S., Threat,T.A., Wang,X., Horton,J.H., Cui,Y., Wang,X.,
            Pryor,E., Paris,J., Wells-Smith,J., Kitchen,J.R., Rowe,L.B.,
            Eppig,J., Satoh,T., Brant,L., Fujiwara,H., Yotsumoto,S. and
            Nakashima,H.
  TITLE     Genome-wide mapping of unselected transcripts from extraembryonic
            tissue of 7.5-day mouse embryos reveals enrichment in the t-complex
            and under-representation on the X chromosome
  JOURNAL   Hum Mol Genet 7 (12), 1967-1978 (1998)
   PUBMED   9811942
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            FJ618908.1 and CO039431.1.
            
            On May 16, 2009 this sequence version replaced NM_001025365.1.
            
            CCDS Note: The coding region has been updated to extend the
            N-terminus, which results in a protein that is 3 aa longer.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FJ618908.1, BC024069.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1800              FJ618908.1         1-1800
            1801-1830           CO039431.1         1-30                c
FEATURES             Location/Qualifiers
     source          1..1830
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 78.56 cM"
     gene            1..1830
                     /gene="Miip"
                     /gene_synonym="D4Wsu114e; IIP45"
                     /note="migration and invasion inhibitory protein"
                     /db_xref="GeneID:28010"
                     /db_xref="MGI:MGI:106506"
     exon            1..351
                     /gene="Miip"
                     /gene_synonym="D4Wsu114e; IIP45"
                     /inference="alignment:Splign:2.1.0"
     exon            352..536
                     /gene="Miip"
                     /gene_synonym="D4Wsu114e; IIP45"
                     /inference="alignment:Splign:2.1.0"
     CDS             414..1577
                     /gene="Miip"
                     /gene_synonym="D4Wsu114e; IIP45"
                     /note="isoform 2 is encoded by transcript variant 2;
                     invasion inhibitory protein 45"
                     /codon_start=1
                     /product="migration and invasion-inhibitory protein
                     isoform 2"
                     /protein_id="NP_001020536.2"
                     /db_xref="CCDS:CCDS18923.2"
                     /db_xref="GeneID:28010"
                     /db_xref="MGI:MGI:106506"
                     /translation="MPNMAETKDPVRLRLLSLELLKQLWAGHEAMCRSVVRAASGSNL
                     DCSSNNLEMPLSQETSSASSVAPSSQDKRHMLDPLDSRRDDTFDVAWYVKFNSRMDSF
                     LPATGQHQEPQEELRPPSVPLLATQGLKGPVSLGGPKGLGPDKTQVPRSILSRLSKPS
                     KPRVTSQESAVPESSWHSRPYLGYDWIAGSLDNSSPVTSEPEAFFSMLQRFRENNKED
                     CVCNSPEAVFPGLQESSGVEEDHECMYCYRINRRLFPEPVDPGAPCRLCGIPRDEKGP
                     GTLVEPVQVRVSIPLSIMDPPHQYRIHRRKSFDASDTLALPRHCLLGWDILPPKSEKT
                     SVPKSLDLWSSVSYGAGQRRDLSATSPPCQALPAQVTPPLWSEPQVAQLCPSH"
     exon            537..896
                     /gene="Miip"
                     /gene_synonym="D4Wsu114e; IIP45"
                     /inference="alignment:Splign:2.1.0"
     exon            897..978
                     /gene="Miip"
                     /gene_synonym="D4Wsu114e; IIP45"
                     /inference="alignment:Splign:2.1.0"
     exon            979..1087
                     /gene="Miip"
                     /gene_synonym="D4Wsu114e; IIP45"
                     /inference="alignment:Splign:2.1.0"
     exon            1088..1140
                     /gene="Miip"
                     /gene_synonym="D4Wsu114e; IIP45"
                     /inference="alignment:Splign:2.1.0"
     exon            1141..1270
                     /gene="Miip"
                     /gene_synonym="D4Wsu114e; IIP45"
                     /inference="alignment:Splign:2.1.0"
     exon            1271..1367
                     /gene="Miip"
                     /gene_synonym="D4Wsu114e; IIP45"
                     /inference="alignment:Splign:2.1.0"
     exon            1368..1505
                     /gene="Miip"
                     /gene_synonym="D4Wsu114e; IIP45"
                     /inference="alignment:Splign:2.1.0"
     exon            1506..1813
                     /gene="Miip"
                     /gene_synonym="D4Wsu114e; IIP45"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1780..1785
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Miip"
                     /gene_synonym="D4Wsu114e; IIP45"
                     /note="hexamer: AATAAA"
     polyA_site      1800
                     /gene="Miip"
                     /gene_synonym="D4Wsu114e; IIP45"
                     /note="major polyA site"
ORIGIN      
        1 accaatcagc aatgaggtcc cattagcccc tcctttccat attgaaactg ccgcttccgg
       61 atgcgaagaa acaaatataa ggcgtcctgg cactgtcaat tggccgagca ggacagcggc
      121 ggaggccccg ccccagcctt agccaattag gacaaccact ggaggttccg cccctgctgg
      181 aggcggattc cccggctgct gggaatctgg gctttcgggc ggagagcgtt ggcgtccttt
      241 tatccatggc agccgctgat ctcgggacca cagaggcgtg ccttcgtccc gctagaccgg
      301 tagagaaggg gcaagcgcct aggccccggt gtgcaccctg cctgagtgcg cgtggaacct
      361 agggtcagca cctctgcagc ccagagacag tgacattact gtgagaagcc cgcatgccca
      421 atatggcaga gactaaagac cccgttcggc ttcggctgct tagcctggag ctcctgaagc
      481 agctttgggc tgggcacgaa gccatgtgtc ggtcggtggt gagagcagca tcagggtcaa
      541 acttggattg tagcagcaac aacttagaga tgccactgtc ccaagagact tcttccgctt
      601 cctcagtggc ccccagctca caggacaaaa gacacatgtt ggacccactg gacagtcgtc
      661 gagatgacac gtttgatgtg gcctggtatg tcaagttcaa ctccaggatg gactctttcc
      721 tacctgccac aggccaacac caggagcccc aggaagaact acggcccccc tcagtaccct
      781 tgctagccac tcagggtctg aaggggccag tgtctttggg aggaccaaaa ggtctgggac
      841 ctgacaagac acaggtccca aggtccatcc tgtcacgact aagcaagcca tctaagccca
      901 gagtgacctc ccaggagtct gcagtgcctg agagcagctg gcactctagg ccatacctag
      961 gctatgattg gattgcaggg tccctggaca atagctctcc agtcactagt gagcccgagg
     1021 ccttcttctc tatgctgcag aggtttcgag aaaacaacaa agaggattgt gtttgcaact
     1081 cccctgaagc tgtgttccca ggcctgcaag agagcagcgg tgtggaagag gaccacgagt
     1141 gtatgtactg ttaccgtatc aaccgccggc tgtttcctga gcctgtggat ccaggcgccc
     1201 cttgccgtct gtgtgggata ccccgggatg agaagggccc cggaactctg gtggagccag
     1261 tgcaagtcag ggtgagcatc cccctatcca tcatggaccc tccacaccag tatcgaattc
     1321 acagaaggaa gagctttgat gcatctgaca ctctagcttt gcctcggcac tgtctgctgg
     1381 gctgggacat cctccctcca aagtcagaga aaacgtctgt ccccaagagc ctggacctct
     1441 ggtcctccgt gtcctatgga gcagggcagc gtcgggatct gtcagccact agcccaccct
     1501 gtcaggcctt gccagcacag gtcacaccac ctctctggtc agagccccag gttgcccagc
     1561 tctgtccctc ccactagaag cccagaggac agacggccca gaagacaaca gtattctacc
     1621 agtgccaaca gcctcccctg aggagaagcc cctgagagct ggaagtggag aagatggagg
     1681 tggctcagct gtctctcctc cattgtcccc tctgtttact gagatactga aagtgggaaa
     1741 tggggtgcag aggggaggga gtgctctgag tagcgtgcta ataaagctca gggtcctaca
     1801 cttcctgtct ccaaaaaaaa aaaaaaaaaa
//
