LOCUS       NM_172593               5277 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus MIER family member 3 (Mier3), mRNA.
ACCESSION   NM_172593 XM_913706
VERSION     NM_172593.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5277)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   2  (bases 1 to 5277)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK147427.1, AK083929.1 and AC118704.17.
            
            On Aug 23, 2007 this sequence version replaced NM_172593.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The extent of this transcript is
            supported by transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK147427.1, AK083929.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-483               AK147427.1         2-484
            484-1095            AK083929.1         323-934
            1096-3326           AK147427.1         1097-3327
            3327-5277           AC118704.17        148646-150596       c
FEATURES             Location/Qualifiers
     source          1..5277
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 63.36 cM"
     gene            1..5277
                     /gene="Mier3"
                     /gene_synonym="5730509D14; D130064H19Rik"
                     /note="MIER family member 3"
                     /db_xref="GeneID:218613"
                     /db_xref="MGI:MGI:2442317"
     exon            1..177
                     /gene="Mier3"
                     /gene_synonym="5730509D14; D130064H19Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             169..1824
                     /gene="Mier3"
                     /gene_synonym="5730509D14; D130064H19Rik"
                     /note="mi-er3; mesoderm induction early response 1, family
                     member 3"
                     /codon_start=1
                     /product="mesoderm induction early response protein 3"
                     /protein_id="NP_766181.2"
                     /db_xref="CCDS:CCDS26770.2"
                     /db_xref="GeneID:218613"
                     /db_xref="MGI:MGI:2442317"
                     /translation="MAEASFGSSSPVGSLSSEDHDFDPTAEMLVHDYDDERTLEEEEL
                     MDDGKNFSSEIEDLEKEGNMPLEDLLAFYGYESTIPAVANSSANSSPSELADELPDMT
                     LDKEEIAKDLLSGDDEETQSSADDLTPSVTSHETSEFFPRPLRSNTTCDGDKESEIED
                     VETDSGNSPEDLRREIMIGLEYQAEIPPYLGEYNGDDEKAYENEDQLLWHPGVLLESK
                     VKEYLVETSLRTGNEKVLDRISSGTHTRDNEQALYELLKCNHNIKEAIERYCCNGKAS
                     QEGMTAWTEEECRSFEHALMLHGKDFHLIQKDKVRSRTVAECVAFYYMWKKSERYDYF
                     AQQTKFGKKRYNHHPGVTDYMDRLVDETESLGGTVSSSALTCNRPEPVPDQPLNILSS
                     FTASDLTALTNSVATVCNPTAVNCLDDSFPPLANTPRGHVNHVPVVTEELLTLPSNGE
                     SDCFNLFETGFYHSELNPMCSEESERPAKRLKMGIAVPESFMNEVSVNNLGVDFENHT
                     HHITSAKMAVSVADFGSLSANETNGFINAHSLHQHQHAALHSE"
     exon            178..202
                     /gene="Mier3"
                     /gene_synonym="5730509D14; D130064H19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            203..348
                     /gene="Mier3"
                     /gene_synonym="5730509D14; D130064H19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            349..483
                     /gene="Mier3"
                     /gene_synonym="5730509D14; D130064H19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            484..604
                     /gene="Mier3"
                     /gene_synonym="5730509D14; D130064H19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            605..690
                     /gene="Mier3"
                     /gene_synonym="5730509D14; D130064H19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            691..766
                     /gene="Mier3"
                     /gene_synonym="5730509D14; D130064H19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            767..918
                     /gene="Mier3"
                     /gene_synonym="5730509D14; D130064H19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            919..1000
                     /gene="Mier3"
                     /gene_synonym="5730509D14; D130064H19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1001..1095
                     /gene="Mier3"
                     /gene_synonym="5730509D14; D130064H19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1096..1223
                     /gene="Mier3"
                     /gene_synonym="5730509D14; D130064H19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1224..1366
                     /gene="Mier3"
                     /gene_synonym="5730509D14; D130064H19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1367..5277
                     /gene="Mier3"
                     /gene_synonym="5730509D14; D130064H19Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2685..2690
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mier3"
                     /gene_synonym="5730509D14; D130064H19Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2711
                     /gene="Mier3"
                     /gene_synonym="5730509D14; D130064H19Rik"
ORIGIN      
        1 gggggcgtcg cgggccggcc tgccctataa ggggccgagc cgcctctgcc tccgggcggg
       61 tgcctggcgg gccgcggcgg cggcagcggc ggcggcggct gcgattggct caggcgcccc
      121 atccggggac tgggctcggc gctgctcgtt cgccctaaag gtaccaatat ggcggaggct
      181 tcctttggaa gttcgagccc agttgggtct ttgtcttctg aggaccatga ctttgacccc
      241 actgctgaga tgctagttca tgactatgat gatgaaagaa ctctagagga agaagagttg
      301 atggacgacg ggaagaactt cagctctgaa attgaagact tagagaagga agggaacatg
      361 ccgctagaag acctgttggc gttctacggc tatgaatcta caattccagc ggttgcgaat
      421 tccagtgcaa acagctcccc aagtgaactt gcagacgaac taccagacat gactctagac
      481 aaagaagaga tcgcgaaaga cctgctgtcc ggcgatgacg aggaaactca gtcttccgct
      541 gatgatctga caccgtccgt gacttctcat gagacttcgg agttcttccc ccggccttta
      601 cgatcaaaca ctacatgtga tggagacaag gagtccgaga ttgaggacgt tgaaacggac
      661 agtggtaact cacctgaaga tttgagaagg gaaataatga ttggtctaga gtatcaggca
      721 gaaattcccc cttatcttgg cgagtacaat ggtgacgacg agaaagctta tgaaaatgag
      781 gaccagttac tgtggcatcc tggtgtgctt ttggagagca aagtcaagga gtaccttgtt
      841 gagacctcat tgagaactgg aaatgaaaaa gtcctagaca ggatttcttc aggcacacac
      901 accagggata atgaacaggc attatacgaa cttctcaagt gtaaccacaa tataaaagaa
      961 gcaattgaaa ggtactgctg taatggaaag gcatctcaag aaggaatgac agcatggacg
     1021 gaagaggagt gccgaagctt tgaacatgca ctgatgcttc atggaaaaga ttttcatctc
     1081 attcagaaag ataaggtgag gtctagaacg gttgccgagt gcgtagcctt ctactacatg
     1141 tggaagaaat cagaacgcta tgattacttt gctcaacaga caaaatttgg aaagaaacgc
     1201 tataaccatc accctggtgt tacggactac atggatcgtc tcgtagatga gacagagtct
     1261 ctgggtggta ccgtcagttc ttcagcctta acttgtaacc ggcctgagcc cgttcctgat
     1321 cagccgctga acattctcag ctccttcact gccagtgacc tgacagcttt aaccaacagt
     1381 gtagcaactg tctgcaaccc caccgctgtg aattgtctgg atgacagctt tcctccgctg
     1441 gccaacacgc ctcgtggaca cgtcaatcat gtgcctgtcg taacggaaga gttactcacc
     1501 ctgcccagca atggtgaaag tgattgtttt aatttatttg agactggatt ttatcactca
     1561 gagttaaacc ccatgtgcag cgaagaatcc gaaagaccag caaagagatt gaagatgggc
     1621 attgctgtcc ccgaatcctt tatgaatgag gtttctgtaa acaacctggg tgtagacttt
     1681 gaaaaccata cacatcacat caccagtgcc aaaatggctg tctctgtagc tgactttggc
     1741 agtttgtctg ccaacgagac aaacggattc atcaatgccc atagtctgca tcagcaccag
     1801 cacgccgccc ttcattcaga gtgatgggaa cgggaagccc agagacaatg ggtatgcagt
     1861 accagtaaac tgaaggggag ctatcaggtt tgcatagtct ttcactggaa gtttgaacct
     1921 ttttcactat gacatcagtg atgtcagtat gtatagaact atatcttgat ttatcaagag
     1981 tattttcatt tttcaatcca taaatgtgga aatgaactat gatccgcaga gttgggaact
     2041 aagatggagc tctgtggtgc agctttaagc tctgcttctc ctcatccctt agtacctctt
     2101 ccacggcctc ctttttttct gttcccgccg ccctcatccc agatttaaaa cctgtagaca
     2161 gaggccacca gctcaaacca gcacagatgt tcagaactga tgtggcctct tttcatgtca
     2221 gctccttttg ccgtaacgga tgcagtggga tcaatgttta caggtaccaa ccccgatccc
     2281 tgttcaatgt agcattatta ttattttttt ttgttttctt tattaataaa agcaggggta
     2341 ggtttcttta aactgcacaa acatgcaagg atttttttta aaaacagaaa cttctctcat
     2401 gttattcaac tagagcactt cagtttacaa aacagcaaga ccatctgtct ggaagccggc
     2461 gcgaggagct gtgtgcaaat gaaggagaca cttgcttgga tcctgtttca aaattccaga
     2521 ccagggctac cttacacaga attggtcatt gtactgccgg gggacttctg tgtaaacttt
     2581 tttttttctt tctttctttt tttttttttt tttttacaaa aaaattggca tttgaagatg
     2641 tggtattcat atggggtttt gtccaccatt gtcaagattg taatattaaa aatcatactg
     2701 gtcactggta atttagtttg ttccgaggca attgacttgc aaggcacagt ctacaaagcc
     2761 caggaagttg ccacagtggt ttacattttg ggacaccttg tttggagcac tgcagttcaa
     2821 agtgttaata tacttagact tctagatggt atacataacg cagacccttg aagctacttt
     2881 gtttagctca aatagttgga aagaaaactg tgagtttctg tctgaagtag aatggtacgt
     2941 taccactttt aagttttaaa acgtgacaga tgttcacgtg catctcagac gtgatttcac
     3001 ttttattcca aacatgagta agaagccatt gtcatagctt tgaccatttt tgctttatta
     3061 gacatgctcc ttttaagttt tcaggtgagt caaactctac aacacagtgt taggatataa
     3121 gctttacttt tacagttaaa acaattactt tttgcaccgt cttaattaaa tattttgatt
     3181 ttttttttta ttttcctagt tgtgttgctg tttataagtg tgagtcgctt caaggtcgtg
     3241 ctgaagagta ggtaggaggt agtggtccta gtgactggac gggagggtat ttattgcaca
     3301 aactgtgaac tgcaatgaca tccttgcttt tggatggtgt gtattgtttt cctttgcagc
     3361 attttaatga agattgcttt gaagtgttta cgcagtagca cattaagtat aaaatttagt
     3421 ttagcacaga ggacaaaggg tagttaaatt aataacttaa aatcagtctt taacttatac
     3481 atctaaaatt gagtattcct gtatgcacac agtaaacaat gggtagcctg ggctccatgt
     3541 tgctttctaa tactctccaa gtggttagct agctttttat tgctgtgctg tgctaaactt
     3601 tgaaccttgg ttttttcgtt cccttcagta gactttcttt aatgtaggag gataccgggc
     3661 atgttcttgc attgttaaaa ctatattttt cactctgggt ttaccgtggc tggtctgtat
     3721 aaatgattta tacaaagata actgaatgct aataccagtt gcacttacat gaaaatgccc
     3781 attctctttg gctggcacag tttatctatg catcgctggg gtcttgatgt aagatggaaa
     3841 cagtgtttct catctagagt tttgattatc agcaagttga atggacactt tagttattta
     3901 aatagagttt tgaccaaaat ccagaaaaat gatatgagag aaataaattc cagctagttt
     3961 aacagatttt taaatgctaa ctggatttta gcctcttaga gagtgctacc tagctggtaa
     4021 cgtttacttt taattccttg ttaaaatgag gcaataattt gcaagatttt tgtatatatg
     4081 tgtacagtaa attcttcata tctttttaga cctaattcaa tattttctga ctgctcctgt
     4141 catgtatgat acatttttgt gcatgcctga tgtgacattc ataaattgta ccactatgac
     4201 tttatccatg taaaatagct atttattgaa tttcttccaa cagctggact tatttttttg
     4261 tctccatttg aacatcttaa cagagaattt gttactgttt attaaaagaa ttgagtttga
     4321 aagcataaaa aatctgcttt gcaatcgtat gaagaaaaac aatgccttta ttatcacgtg
     4381 ttaataagca caattcttat agcaaacggt gatgaattct ttgtttcttt catttgccgc
     4441 aatattttca tatgaacaaa ccaaaaatcc atggtgagca gtggcggtgt cggctggccc
     4501 atcctgtgtg tccagggcac tcggaggatg tggacgttga cgagtgtgac ctggtgctgt
     4561 gactggagca atactttact ttcgtcacgt gtgcttcgcc gtgctatgcc ggccttttaa
     4621 tgtttagttt tcctcttgtc atggtcaact gctgaattta cttgaaggat gtagaatact
     4681 atttaaaaaa aaaaaaacac aaaaaaccta aagtctgtac aattaggtca aagaattgtg
     4741 caatcgcttc ctttttaatt tttaaaattg aaggtcacaa atatttgcga tcagacctaa
     4801 tagagtagta gcgctattta atttaaccaa agtctagtaa atacttcaac gttgaatgta
     4861 agctaacaac ccgaccacca aggagattgt ctgcccagag tttcaaagca cattgtctac
     4921 gaatggaaat tgaaataatt tataaaatat tgacattact atgtttttta aaaagttcct
     4981 aattttttca ctaaaaggag ggaaactatt agttttattg ttaaatatgg tagatattaa
     5041 tattcctctt agatgaccag tgattgcaat tgtcccagtt tgaactaagt accctgtgag
     5101 tatgaggaac tagtgacaat cagaacaagt tttagtatcc agtgttcaag aggaagttgc
     5161 tattgttgca ttgattttaa tatttgtaca taaacactga ttttttgagc attattttgt
     5221 atttgttgta ctttaatacc tggtgtacag ttccagaaat aaaaatctgg gaatctg
//
