LOCUS       NM_025559                762 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus migration and invasion enhancer 1 (Mien1), mRNA.
ACCESSION   NM_025559
VERSION     NM_025559.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 762)
  AUTHORS   Tripathi,A.K., Desai,P.P., Tyagi,A., Lampe,J.B., Srivastava,Y.,
            Donkor,M., Jones,H.P., Dzyuba,S.V., Crossley,E., Williams,N.S. and
            Vishwanatha,J.K.
  TITLE     Short peptides based on the conserved regions of MIEN1 protein
            exhibit anticancer activity by targeting the MIEN1 signaling
            pathway
  JOURNAL   J Biol Chem 300 (3), 105680 (2024)
   PUBMED   38272230
  REMARK    GeneRIF: Short peptides based on the conserved regions of MIEN1
            protein exhibit anticancer activity by targeting the MIEN1
            signaling pathway.
REFERENCE   2  (bases 1 to 762)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 762)
  AUTHORS   Dikiy,A., Novoselov,S.V., Fomenko,D.E., Sengupta,A., Carlson,B.A.,
            Cerny,R.L., Ginalski,K., Grishin,N.V., Hatfield,D.L. and
            Gladyshev,V.N.
  TITLE     SelT, SelW, SelH, and Rdx12: genomics and molecular insights into
            the functions of selenoproteins of a novel thioredoxin-like family
  JOURNAL   Biochemistry 46 (23), 6871-6882 (2007)
   PUBMED   17503775
REFERENCE   4  (bases 1 to 762)
  AUTHORS   Mu,X., Zhao,S., Pershad,R., Hsieh,T.F., Scarpa,A., Wang,S.W.,
            White,R.A., Beremand,P.D., Thomas,T.L., Gan,L. and Klein,W.H.
  TITLE     Gene expression in the developing mouse retina by EST sequencing
            and microarray analysis
  JOURNAL   Nucleic Acids Res 29 (24), 4983-4993 (2001)
   PUBMED   11812828
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BE623929.1, AK007795.1 and CA530220.1.
            
            On Aug 2, 2006 this sequence version replaced NM_025559.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CF617659.1, SRR1660815.437467.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-50                BE623929.1         1-50
            51-727              AK007795.1         34-710
            728-762             CA530220.1         554-588
FEATURES             Location/Qualifiers
     source          1..762
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 61.75 cM"
     gene            1..762
                     /gene="Mien1"
                     /gene_synonym="1810046J19Rik; Rdx12"
                     /note="migration and invasion enhancer 1"
                     /db_xref="GeneID:103742"
                     /db_xref="MGI:MGI:1913678"
     exon            1..131
                     /gene="Mien1"
                     /gene_synonym="1810046J19Rik; Rdx12"
                     /inference="alignment:Splign:2.1.0"
     CDS             43..390
                     /gene="Mien1"
                     /gene_synonym="1810046J19Rik; Rdx12"
                     /note="protein C17orf37 homolog"
                     /codon_start=1
                     /product="migration and invasion enhancer 1"
                     /protein_id="NP_079835.1"
                     /db_xref="CCDS:CCDS25350.1"
                     /db_xref="GeneID:103742"
                     /db_xref="MGI:MGI:1913678"
                     /translation="MSGEPAPVSVVPPPGEVEAGSGVHIVVEYCKPCGFEATYLELAS
                     AVKEEYPGIEIESRLGGTGAFEIEINGQLVFSKLENGGFPYEKDLMEAIRRASNGEPV
                     EKITNSRPPCVIL"
     exon            132..229
                     /gene="Mien1"
                     /gene_synonym="1810046J19Rik; Rdx12"
                     /inference="alignment:Splign:2.1.0"
     exon            230..306
                     /gene="Mien1"
                     /gene_synonym="1810046J19Rik; Rdx12"
                     /inference="alignment:Splign:2.1.0"
     exon            307..744
                     /gene="Mien1"
                     /gene_synonym="1810046J19Rik; Rdx12"
                     /inference="alignment:Splign:2.1.0"
     regulatory      714..719
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mien1"
                     /gene_synonym="1810046J19Rik; Rdx12"
                     /note="hexamer: AATAAA"
     regulatory      725..730
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mien1"
                     /gene_synonym="1810046J19Rik; Rdx12"
                     /note="hexamer: ATTACA"
     polyA_site      732
                     /gene="Mien1"
                     /gene_synonym="1810046J19Rik; Rdx12"
                     /note="major polyA site"
     polyA_site      744
                     /gene="Mien1"
                     /gene_synonym="1810046J19Rik; Rdx12"
ORIGIN      
        1 ggcgtcacac ccggaagcag ccctgcagcg gagcgggcag caatgagtgg ggagccagcg
       61 ccggtgtccg tagtgccccc tcccggggag gtggaagcag gcagtggagt ccacatcgtg
      121 gtggagtact gtaaaccctg cggctttgag gcgacctacc tggagctggc gagcgctgtg
      181 aaggaggagt atccgggcat tgagattgag tcgcgactcg gggggacagg ggccttcgag
      241 attgagatca atggacagct ggtgttctcc aagctggaga atggagggtt tccttatgag
      301 aaagacctca tggaagccat ccgaagagcc agcaatggag aacctgtaga aaagatcacc
      361 aacagccggc ctccctgtgt catcctgtga ctaagaaatg attcttggaa gcttggttct
      421 ggggtttaaa cctttccttg tggttacgct aggaatccct ctacctttag cccctcactt
      481 ggccctaggt aactaagacc ctgacttcac tttgcctctt agggcacaag gagggactag
      541 acatttctgt ggccaaaggc agaaaagaga tgttctctgt gaacatcacc atcgctctcc
      601 cgggatctgt gccctctgca gtttggtcct ctccccagcg tggcaatacc tttcagatgc
      661 cacggttgct ataacttatt ttccctgaat cctgggcagt gtcggctctt ggcaataaag
      721 agtaattaca aatgcttgtg tcaaaaaaaa aaaaaaaaaa aa
//
