LOCUS       NM_134100               1742 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus major facilitator superfamily domain containing 5
            (Mfsd5), mRNA.
ACCESSION   NM_134100
VERSION     NM_134100.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1742)
  AUTHORS   Perland,E., Lekholm,E., Eriksson,M.M., Bagchi,S., Arapi,V. and
            Fredriksson,R.
  TITLE     The Putative SLC Transporters Mfsd5 and Mfsd11 Are Abundantly
            Expressed in the Mouse Brain and Have a Potential Role in Energy
            Homeostasis
  JOURNAL   PLoS One 11 (6), e0156912 (2016)
   PUBMED   27272503
  REMARK    GeneRIF: Results show that Mfsd5 and Mfsd11 are both affected by
            altered energy homeostasis, suggesting plausible involvement in the
            energy regulation. Moreover, the first histological mapping of
            MFSD5 and MFSD11 shows ubiquitous expression in the periphery and
            the central nervous system of mice, where the proteins are
            expressed in excitatory and inhibitory mouse brain neurons.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1742)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
REFERENCE   3  (bases 1 to 1742)
  AUTHORS   Lin,Q., Donahue,S.L., Moore-Jarrett,T., Cao,S., Osipovich,A.B. and
            Ruley,H.E.
  TITLE     Mutagenesis of diploid mammalian genes by gene entrapment
  JOURNAL   Nucleic Acids Res 34 (20), e139 (2006)
   PUBMED   17062627
REFERENCE   4  (bases 1 to 1742)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK089268.1.
            
            On Dec 13, 2008 this sequence version replaced NM_134100.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK087550.1, AK089268.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1742              AK089268.1         4-1745
FEATURES             Location/Qualifiers
     source          1..1742
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="NOD"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 57.44 cM"
     gene            1..1742
                     /gene="Mfsd5"
                     /gene_synonym="AW556797; D15Mgi27"
                     /note="major facilitator superfamily domain containing 5"
                     /db_xref="GeneID:106073"
                     /db_xref="MGI:MGI:2145901"
     exon            1..174
                     /gene="Mfsd5"
                     /gene_synonym="AW556797; D15Mgi27"
                     /inference="alignment:Splign:2.1.0"
     exon            175..1742
                     /gene="Mfsd5"
                     /gene_synonym="AW556797; D15Mgi27"
                     /inference="alignment:Splign:2.1.0"
     CDS             193..1545
                     /gene="Mfsd5"
                     /gene_synonym="AW556797; D15Mgi27"
                     /note="major facilitator superfamily domain-containing
                     protein 5; molybdate transporter 2 homolog"
                     /codon_start=1
                     /product="molybdate-anion transporter"
                     /protein_id="NP_598861.1"
                     /db_xref="CCDS:CCDS27877.1"
                     /db_xref="GeneID:106073"
                     /db_xref="MGI:MGI:2145901"
                     /translation="MLVTAYLSFVGLLASCLGLELSRCRARPPGRACSNPSFLQFQLD
                     FYQVYFLALAADWLQAPYLYKLYQHYHFLEGQIAILYVCGLASTVLFGLVASSLVDWL
                     GRKKSCVLFSLTYSLCCITKLSQDYFVLLVGRALGGLSTALLFSAFEAWYIHEHVERH
                     DFPAEWIPATFARAAFWNHVLAVAAGVAAEAVASWIGLGPVAPFVAAIPLLALTGALA
                     LRNWGENYDRQRAFSKTCAGGLRCLLSDRRVLLLGVIQALFESVIFIFVFLWTPVLDP
                     HGAPLGIVFSSFMAASLLGSSLYRIATSKRYHLQPMHLLSLAVLIVVFSLFMLTFSTS
                     PGQENPVESFIAFLLIELACGLYFPSMSFLRRKVIPETEQAGVLNWFRVPLHLLACLG
                     LLVLHDSDRKTGTRNMFSICSAVMVTTLLAVAGLFTVVRHDAELRVPSPTGEPYAPEL
                     "
     polyA_site      1742
                     /gene="Mfsd5"
                     /gene_synonym="AW556797; D15Mgi27"
                     /note="putative"
ORIGIN      
        1 cacgtgacgg ggctatcatg gcggcggcca cgagccagcc cggctcccgg aagcaggctg
       61 tgaggggcgg gcgcgctgct ggaacccgag cggagccgga gccagtgcgg ggagggcggc
      121 ccggcggcct ggagccggac gtgtccggag cgtcccggca gaccggggca gcaggtcgtc
      181 cgggggccca tcatgctggt gactgcctat ttgtcttttg tgggcctcct ggcctcctgc
      241 ctgggtctgg agctgtcaag atgcagagcc aggccccctg gaagagcttg cagcaacccc
      301 tccttccttc agtttcaact agacttctat caagtctact ttctggccct ggcagcggac
      361 tggctccaag ctccctacct gtataaactc tatcagcatt accacttcct ggagggtcag
      421 attgctatcc tctacgtctg tggccttgcc tccacggtcc tctttggcct agtggcctcc
      481 tcccttgtgg actggctggg tcgtaagaag tcttgtgtcc tcttctccct cacttactct
      541 ctatgttgca taaccaagct ctctcaggac tacttcgtgc tgctggtggg ccgagcactc
      601 ggtgggctgt ccacagctct cctcttctca gcctttgagg cctggtacat ccacgagcac
      661 gtggagaggc atgacttccc cgccgagtgg atcccagcca cctttgcccg agccgccttc
      721 tggaaccacg tgctggctgt ggcggctggt gtggcagcgg aggccgtggc tagttggata
      781 gggctggggc cggtcgcacc ctttgtggct gccatccctc ttctggctct gactggggcc
      841 ttggctctac gaaactgggg agagaattat gaccgtcagc gtgccttctc caagacctgt
      901 gctggaggcc tgcgctgcct gctgtctgac cgccgggtgt tgctgttggg tgtcatacaa
      961 gcgctgtttg agagtgtcat ctttatcttt gtcttcctct ggacacctgt gctagaccca
     1021 cacggagccc cactgggcat tgtgttctcc agcttcatgg ctgccagcct tctgggttct
     1081 tcgctgtacc gcatcgctac ctccaagagg taccaccttc agcccatgca cctgctttcc
     1141 cttgctgtcc tcattgtcgt cttctctctc ttcatgttga ctttctccac cagcccaggc
     1201 caagaaaatc ctgtggagtc cttcattgcc tttttactta ttgagttggc ctgcgggctc
     1261 tactttccca gtatgagctt cctgcgaagg aaagtgatcc ccgagacaga gcaggccggg
     1321 gttctcaatt ggttccgagt gcccctgcat ttgctggcct gtctagggct ccttgtcctc
     1381 cacgacagcg atcggaaaac aggcaccagg aatatgttta gcatctgctc tgccgtcatg
     1441 gtgacgactc tgctggcagt ggcaggactc ttcaccgtgg tgagacacga cgctgagttg
     1501 cgggtgccct cacccaccgg ggagccctac gcccctgaac tttgatcctc caggacaagg
     1561 ggtctgagat gggctctgga acacacccac ctacccatga cttgctttgt gactctgtcc
     1621 tgcagcccct cttgccagtg ctctgtattg ggaaggacat gggggtgaca gactggaaag
     1681 gtgccaaaag ctgacagtgt actcccttct ccttgctgtg taaaaataaa cacttctaat
     1741 gg
//
