LOCUS       NM_178620               3143 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus major facilitator superfamily domain containing 11
            (Mfsd11), transcript variant 1, mRNA.
ACCESSION   NM_178620 XM_992915
VERSION     NM_178620.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3143)
  AUTHORS   Perland,E., Lekholm,E., Eriksson,M.M., Bagchi,S., Arapi,V. and
            Fredriksson,R.
  TITLE     The Putative SLC Transporters Mfsd5 and Mfsd11 Are Abundantly
            Expressed in the Mouse Brain and Have a Potential Role in Energy
            Homeostasis
  JOURNAL   PLoS One 11 (6), e0156912 (2016)
   PUBMED   27272503
  REMARK    GeneRIF: Results show that Mfsd5 and Mfsd11 are both affected by
            altered energy homeostasis, suggesting plausible involvement in the
            energy regulation. Moreover, the first histological mapping of
            MFSD5 and MFSD11 shows ubiquitous expression in the periphery and
            the central nervous system of mice, where the proteins are
            expressed in excitatory and inhibitory mouse brain neurons.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3143)
  AUTHORS   Sureau,A., Soret,J., Guyon,C., Gaillard,C., Dumon,S., Keller,M.,
            Crisanti,P. and Perbal,B.
  TITLE     Characterization of multiple alternative RNAs resulting from
            antisense transcription of the PR264/SC35 splicing factor gene
  JOURNAL   Nucleic Acids Res 25 (22), 4513-4522 (1997)
   PUBMED   9358160
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC100547.1 and BC088988.1.
            
            On Mar 29, 2018 this sequence version replaced NM_178620.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088988.1, AK032043.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-15                BC100547.1         143-157
            16-3143             BC088988.1         1-3128
FEATURES             Location/Qualifiers
     source          1..3143
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 81.49 cM"
     gene            1..3143
                     /gene="Mfsd11"
                     /gene_synonym="2600014M03Rik"
                     /note="major facilitator superfamily domain containing 11"
                     /db_xref="GeneID:69900"
                     /db_xref="MGI:MGI:1917150"
     exon            1..174
                     /gene="Mfsd11"
                     /gene_synonym="2600014M03Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             79..1428
                     /gene="Mfsd11"
                     /gene_synonym="2600014M03Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     UNC93-like protein MFSD11; protein ET; major facilitator
                     superfamily domain-containing protein 11"
                     /codon_start=1
                     /product="UNC93-like protein MFSD11 isoform 1"
                     /protein_id="NP_848735.1"
                     /db_xref="CCDS:CCDS25681.1"
                     /db_xref="GeneID:69900"
                     /db_xref="MGI:MGI:1917150"
                     /translation="MSPESKKLFNIVILGVAFMFMFTAFQTCGNVAQTVIRSLNSTDF
                     HGSGYTSLAIIYGVFSASNLITPSVVAIVGPQISMFVSGLFYSMYIAVFIQPFPWSFY
                     TASVFIGIAAAVLWTAQGNCLTINSDEHTIGRNSGIFWALLQSSLFFGNLYIYFAWQG
                     KTQISEHDRRTVFIALTVISLVGTVLFFLIRKPDPENVLGEEESCDDQDMEATESAQN
                     NVTKAVDAFKKSLRLCVTREMLLLSVTTAYTGLELTFFSGVYGTCIGAVNKFGTEEKS
                     LIGLSGIFIGIGEILGGSLFGLLSKNSRFGRNPVVLLGTLVHFVAFYLIFLNMPGDAP
                     IAPVEGTNSIAYIRPSKEVAILCSFLLGLGDSCFNTQLLSILGFLYSEDSAPAFAVFK
                     FVQSICAAVAFFYSNYLLLHWQLLVMVIFGFFGTISFFAVEWDAAAIVARGSDYRSI"
     exon            175..230
                     /gene="Mfsd11"
                     /gene_synonym="2600014M03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            231..338
                     /gene="Mfsd11"
                     /gene_synonym="2600014M03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            339..418
                     /gene="Mfsd11"
                     /gene_synonym="2600014M03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            419..515
                     /gene="Mfsd11"
                     /gene_synonym="2600014M03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            516..574
                     /gene="Mfsd11"
                     /gene_synonym="2600014M03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            575..719
                     /gene="Mfsd11"
                     /gene_synonym="2600014M03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            720..760
                     /gene="Mfsd11"
                     /gene_synonym="2600014M03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            761..826
                     /gene="Mfsd11"
                     /gene_synonym="2600014M03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            827..952
                     /gene="Mfsd11"
                     /gene_synonym="2600014M03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            953..1127
                     /gene="Mfsd11"
                     /gene_synonym="2600014M03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1128..1263
                     /gene="Mfsd11"
                     /gene_synonym="2600014M03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1264..3143
                     /gene="Mfsd11"
                     /gene_synonym="2600014M03Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2175..2180
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mfsd11"
                     /gene_synonym="2600014M03Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2195
                     /gene="Mfsd11"
                     /gene_synonym="2600014M03Rik"
                     /note="major polyA site"
     regulatory      2343..2348
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mfsd11"
                     /gene_synonym="2600014M03Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2363
                     /gene="Mfsd11"
                     /gene_synonym="2600014M03Rik"
     regulatory      2890..2895
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mfsd11"
                     /gene_synonym="2600014M03Rik"
                     /note="hexamer: ATTAAA"
     regulatory      2918..2923
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mfsd11"
                     /gene_synonym="2600014M03Rik"
                     /note="hexamer: ATTACA"
     polyA_site      2921
                     /gene="Mfsd11"
                     /gene_synonym="2600014M03Rik"
     polyA_site      2940
                     /gene="Mfsd11"
                     /gene_synonym="2600014M03Rik"
ORIGIN      
        1 ggctgtcagg gggttcgact ggaggagaag aggtgactgt cctgggccgc tgctggcctc
       61 tgagcaagcg gagccaaaat gtccccggag tctaaaaagc ttttcaacat cgttatttta
      121 ggagttgcct ttatgtttat gttcaccgcc tttcagactt gtggaaatgt ggcgcaaact
      181 gtcatcagga gcttaaatag cacagatttt catggcagtg gatataccag cttggcaatt
      241 atttatggcg tgttctctgc ttcaaatttg atcactccgt ccgtggtcgc cattgttgga
      301 cctcagatct ctatgtttgt cagtggtttg ttttacagca tgtacattgc cgtttttatc
      361 cagcctttcc catggtcctt ctacacagca tctgtcttca tcggaattgc cgctgctgtc
      421 ctttggacag cacaaggaaa ttgcctgacg ataaattctg atgagcacac aatcgggaga
      481 aacagcggaa ttttctgggc actcttacag tctagcttgt tctttgggaa tctctacata
      541 tattttgcat ggcaagggaa gacccagatc tcagagcatg accgaaggac agtgtttatt
      601 gctctgacag tgataagcct cgtggggacc gttctgttct ttctcattcg gaaaccagat
      661 cctgagaatg tccttggaga agaagagtct tgcgatgacc aggacatgga agccaccgag
      721 tctgcccaga acaacgtgac aaaggcagtc gatgcgttta aaaagtctct gaggctgtgt
      781 gtcaccaggg agatgctgct cctgagcgtc acgactgcct acacaggtct ggagctgacc
      841 ttcttctctg gggtgtacgg tacctgtatt ggggccgtaa acaaatttgg gacagaagag
      901 aaaagcctca ttggactttc tggaattttc atcggcattg gagagatttt aggtgggagc
      961 ctcttcggcc tgctgagcaa gaacagtcgc tttggcagga acccggtcgt gctgctcggc
     1021 accctggtgc acttcgtagc cttctacttg atctttctca acatgcccgg agacgcgccc
     1081 attgcccctg tggaagggac caacagcatt gcatacatca ggcccagcaa agaagttgcc
     1141 attctctgca gttttctgct gggtctggga gacagctgct tcaacaccca gctgcttagc
     1201 attctgggtt ttctctactc ggaagacagc gcgccggcct tcgcggtctt taagtttgtt
     1261 cagtcaatct gcgcagccgt ggcctttttc tacagcaact acctcctcct ccactggcag
     1321 ctcctggtca tggtgatatt tgggtttttt ggaaccattt ctttcttcgc tgtggagtgg
     1381 gacgctgctg ccatcgtggc ccgaggctcg gactaccgaa gcatttgatg agaaaacaag
     1441 tgtctccaag aaacacagct ggtcacatgg cagctggtta aatccgacgg cctgtcagtc
     1501 tcataatcgc taaagcgaga acggagactg tgaaatcggg cggggttggt agtaaagttt
     1561 acatatccta gcggcacacg ctagcggagg aagggaatcc cgctctatcc gttacagctg
     1621 ttctgagatg ttcgtccacc ccctccctca gttcctcaca atcagggctc ctccatcctc
     1681 attctcgagg aacgatccag cctggctcgc catgtgtcac gagatccttg ctggctgtgg
     1741 agtatgcctc actctttcga aataggaagc agatgccact ccatgtgtgg gtctgggaat
     1801 gactttctga aacacagcaa ggatgctgag acacgttgtt ttgagacagg atctcactgc
     1861 gtagcccagg ctggtcttgg acttgcagcc ctcccctgcc tccagtgttg gggttattgc
     1921 ccaacactgg atttaaaacg ctccaatcct aagagttagg gtcttgatat gcagccttgg
     1981 ctggcctgga ctttgtatac caggcaatgc tcctgccttt gtctccagaa tgcctgggtg
     2041 gtgagaatat gctaccacac accgctgaga cttcaacttc tcctaaaatg ctttgttgaa
     2101 caagtcttac cttgtcactc ccagcaaggg gctggttatg tgtaatgagg taaagactgt
     2161 gtcatttgtc aactaataaa agcatattta gagaaggaaa gagtatttac tgggaggggg
     2221 aggactcatg ctgtggttgt cctgaccgtt acaataaaga aaactccggc catcctctgt
     2281 gggaaagtgc gtaagcactg cagactgtct cccacaagga ctgacactct tacgattgag
     2341 atattaaatt aattaagcat ctagatcagg tctaacatgt atgtactgca gcttggcctc
     2401 caacttgtgc tcttccaagc cacaaacaac ctctggctaa aattcaccaa cttagtgtgt
     2461 atgtgtggtg tgtgtgcata aggttgtata actgccacca tatctaatga caatatttta
     2521 tttttaaatt cttttttatt ttatttatta gtgtatgtgt ttgcctgtgg cttgtctgta
     2581 tatacattct gcctacagaa ctcagagaag tcagatggag attggatccc tgcgaactgc
     2641 atttacaggc agttaaagac cactgatatg gggtgcgttc tctggtgtct tagttacttt
     2701 cctcttgtga agagatacca aggcaacttg tttcgagaca gggtttctct gtgtagcact
     2761 ggctgtcctt gaactcacga ggctggagaa tctggttgag tgctgggatt aaagtgtcca
     2821 ctatttcttt gttttgtgtc gatgtacctt gacggatgta ttcgcctagc tttcttgttt
     2881 ttcttctgta ttaaaagtct ggtgcctgct tggaaaaatt acattaagat acacagtcaa
     2941 gggctggcga gatggctcag tgggtaagag cacccgactg ctcttccgaa ggtccagagt
     3001 tcaaatccca gcaaccacat ggtggctcac aaccatcccc aacaagatct gactccctct
     3061 tctagagtgt ctgaagacag ctacagtgta cttacatata atcaataaat aaatctttaa
     3121 aaaaaaaaaa aaaaaaaaaa aaa
//
