LOCUS       NM_180599               4828 bp    mRNA    linear   ROD 29-JUL-2024
DEFINITION  Mus musculus microfibrillar-associated protein 3 (Mfap3),
            transcript variant 2, mRNA.
ACCESSION   NM_180599
VERSION     NM_180599.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4828)
  AUTHORS   Vincentz,J.W., Firulli,B.A., Toolan,K.P., Arking,D.E.,
            Sotoodehnia,N., Wan,J., Chen,P.S., de Gier-de Vries,C.,
            Christoffels,V.M., Rubart-von der Lohe,M. and Firulli,A.B.
  TITLE     Variation in a Left Ventricle-Specific Hand1 Enhancer Impairs GATA
            Transcription Factor Binding and Disrupts Conduction System
            Development and Function
  JOURNAL   Circ Res 125 (6), 575-589 (2019)
   PUBMED   31366290
REFERENCE   2  (bases 1 to 4828)
  AUTHORS   Gu,Z., Imai,F., Kim,I.J., Fujita,H., Katayama,Ki., Mori,K.,
            Yoshihara,Y. and Yoshida,Y.
  TITLE     Expression of the immunoglobulin superfamily cell adhesion
            molecules in the developing spinal cord and dorsal root ganglion
  JOURNAL   PLoS One 10 (3), e0121550 (2015)
   PUBMED   25826454
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4828)
  AUTHORS   Georgas,K.M., Chiu,H.S., Lesieur,E., Rumballe,B.A. and Little,M.H.
  TITLE     Expression of metanephric nephron-patterning genes in
            differentiating mesonephric tubules
  JOURNAL   Dev Dyn 240 (6), 1600-1612 (2011)
   PUBMED   21491542
REFERENCE   4  (bases 1 to 4828)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CF174749.1 and AL672236.18.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CF174749.1, AK076071.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-570               CF174749.1         1-570
            571-4828            AL672236.18        179017-183274
FEATURES             Location/Qualifiers
     source          1..4828
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 35.27 cM"
     gene            1..4828
                     /gene="Mfap3"
                     /gene_synonym="2610509F16Rik; 2700079M14Rik"
                     /note="microfibrillar-associated protein 3"
                     /db_xref="GeneID:216760"
                     /db_xref="MGI:MGI:1924068"
     exon            1..48
                     /gene="Mfap3"
                     /gene_synonym="2610509F16Rik; 2700079M14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            49..479
                     /gene="Mfap3"
                     /gene_synonym="2610509F16Rik; 2700079M14Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             206..1255
                     /gene="Mfap3"
                     /gene_synonym="2610509F16Rik; 2700079M14Rik"
                     /note="microfibril-associated glycoprotein 3; novel
                     immunoglobulin domain containing protein"
                     /codon_start=1
                     /product="microfibril-associated glycoprotein 3 precursor"
                     /protein_id="NP_850930.1"
                     /db_xref="CCDS:CCDS24718.1"
                     /db_xref="GeneID:216760"
                     /db_xref="MGI:MGI:1924068"
                     /translation="MKLHHCLSILLVVTLVPAALGLEDVAPLGANQSSYNASFLPSFE
                     LSAGSYSGDDVIIVKEGTNVSLECLLTVDQYGEVHWYNSKGQQLHSRGGKWLVSDNFL
                     NITSVAFDDRGLYTCIITSPARASYSVTLRVIFTSGDMSVYYMVVCLIAFTITLILNV
                     TRLCLMSTHLRKTEKAINEFFRTEGAEKLQKAFEIAKRIPIITSAKTLELAKVTQFKT
                     MEFARYIEELARSVPLPPLILNCRAFVEEMFEAVRVDDPDDMGERIKERPALDAQSGI
                     YVINPELGRSNSPGGDSDDGSLSEQGQEIAVQVSVHLQSETKSIGTDSQDSSHFSPPS
                     DPASAEGSIHHRVSI"
     exon            480..4828
                     /gene="Mfap3"
                     /gene_synonym="2610509F16Rik; 2700079M14Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4802..4807
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mfap3"
                     /gene_synonym="2610509F16Rik; 2700079M14Rik"
                     /note="hexamer: AATAAA"
     polyA_site      4822
                     /gene="Mfap3"
                     /gene_synonym="2610509F16Rik; 2700079M14Rik"
                     /note="major polyA site"
ORIGIN      
        1 cttccgggtc aagcatcctc tagggcggaa ggcgctgact gcagagaggc tggcctccac
       61 attcatcttt tagttttgaa agcctcagaa taccttggac cacttctttg gaaaactttt
      121 ctcccagcaa caagtcattc actgcgatcc tcctcggcca cgtttgagtt ttccaagtct
      181 aaacaggact gcctttgatt ttcccatgaa gctgcatcac tgcctgtcca tcttactggt
      241 ggtcactctt gtgccagctg ctctgggttt ggaagatgtg gctccactgg gagcgaatca
      301 aagttcttac aatgcatcat ttctcccaag ctttgaactc tcagcaggtt cctactcagg
      361 tgatgatgtc attatagtca aagagggaac aaatgtttca ttggagtgtc ttctcacggt
      421 ggatcagtat ggagaagtcc actggtacaa ctcaaaagga cagcagctgc acagcagagg
      481 tggaaaatgg ttggtttctg ataacttcct aaatatcacc agcgtagcct ttgatgaccg
      541 tgggctctat acatgtatca tcacttctcc agctcgtgcc tcctactccg tcaccctccg
      601 tgtgatcttc acctctggag acatgagtgt ctactatatg gttgtctgcc tgatcgcctt
      661 cacaatcaca ctcatcctga acgtcactcg gctgtgcctg atgagcaccc acctccgcaa
      721 gactgagaag gccatcaatg agttcttcag gaccgagggg gctgagaaac tccagaaggc
      781 ctttgagatt gccaagcgca tccccatcat cacctcagcc aaaaccctcg agctggccaa
      841 ggtcacacag tttaagacca tggagtttgc ccgatatatt gaggaactgg ccagaagtgt
      901 ccctctcccg ccccttattc tgaactgccg ggcctttgtt gaggaaatgt ttgaagctgt
      961 ccgagtggat gaccctgatg acatgggaga gagaattaaa gagagacctg ctttggacgc
     1021 tcaaagtggc atctatgtga ttaacccaga gctaggccga agcaactctc ctggtggaga
     1081 ttcagatgat ggttctctaa gcgagcaagg gcaggagata gcagtacagg tgtctgtcca
     1141 ccttcagtca gagaccaaaa gcattgggac agattctcaa gacagtagtc atttcagccc
     1201 acccagtgac cctgcatctg cagagggcag cattcaccac agagtgagca tatgacaact
     1261 gacagcttgc ccagtgctca ggaaaagagc ctgctatgag aatataacat aaaatgacca
     1321 gggtcttccc gttaacctta aacacaccac agcatgaatt gccaaagtca ttgtgaaagg
     1381 gcagcatttt tctgatattt ggtcattttc cttaaggttg ctggagtgat gtgtgttaag
     1441 attgaaaggt gcctgggcct gagtaagact tctctggtca cagtttttct ttggctcatg
     1501 tgtgacacat tgaagcctga gtttccccat cagtagaatc agtgatttgt tctccttgag
     1561 ttgggacttc aaccaaaact tcttacctac tgcacctcta agtcagcctt tcactagatc
     1621 tttggtccat cctttgagac cttattctgc actctaattg tctacaccag tgccagacat
     1681 ggagatactc tgccctgggg agtgagcatg tgctggtgca gattttaagt gaggcaccac
     1741 ttagttacac agatctagaa agtaaaaatc actctcacgg ggtgtggtag cacacatctt
     1801 taattccagc actagagaga caaagatggg cagatccctg agttccaggc gcaaatccag
     1861 gagagccaga gctacactga gaaaccctgt ctcaaaaaaa aaaaaaaaaa caaaaaaaga
     1921 ggacgaggag aagaaaacca ctctctccat gagaagtgta tgtattcttc ttgggagtac
     1981 atccttttta gcttaccaag acctttagtc catcgaggct ggccttgatg ttcccagggg
     2041 aaaatgtaat tggtgttttg tgaacaagaa ctgtgtcaag tcacctctct ggaaattcat
     2101 cagtttagat actttttaat aatgtctcag gctctctctt tttagacgta ctaaattccc
     2161 aggtgggctc tgtgtaggtc tcgaactgca gaatccgctt cagtgcccca tgtccctcaa
     2221 cctggtgcta acggtgattc gcctcttctt gtcctgctga gactcagtgt cagtgttttg
     2281 ggtcttcgga tgcatccttt tgagtgaggg ctcttttgta gcctttctcg aagctcctac
     2341 ctgaaatcgg atgagagcac tgtgctcagt gcataattat attaaaacgg gcaatccaga
     2401 cctaaggggg gaaatgataa ggggtggtgc tgcccacctc atccgggtgc agtgagcact
     2461 gaagctggcc agcccttcct gctggctgag agtgacgtga cagattgtaa atagtcttaa
     2521 caatcgtttc ctccactgca ggaagctcgt gccatagatt tttaacctca tggccgtgga
     2581 gctcattgtg atgcttcact gcatttggct tctgattgtg ggagatctgc ttgagctcga
     2641 aggtcctgag ggaaatgtaa agtgtcaaac aaacagagga cagcaggaga ttcaaactgt
     2701 aaccagtgag ctcagtgcct gcctttgtcg ggctcatcac ctccactcta gacaatgtga
     2761 acgaatcagt gtgcactttt atcaagtggc atatggataa tatggtaata ctgccttttc
     2821 tgtctctcag gctgtttcca tggaaacttc cagggccaaa caaaagcttc caatcattca
     2881 accaaaagct tgccttggct cagagatgtg agtttcttta aggaaagctg ttttcctata
     2941 tttggctgta gaataagggc tcttacacat atcctaagtt acagaacatg atttcccttc
     3001 ctactgttct ctggacatgg taaattttta aaaatctctt ctgtgggggt cagtctcctg
     3061 aatttccctc atatctgcag tccttcgcct gataaagcaa ggttggggtc acttcttaca
     3121 atgaagcctt ttgccttaaa tactggtttt acccccacgt ttcctagaag ggacattgtc
     3181 ttgaacttca aggtagacat attgaatgac cagagtttta gaaaatgata ctttgcaaaa
     3241 aatggaaaat atcaaaacag ttgggtaagc ttatagaatt tatataggcc actccaccgt
     3301 agcctaggtc agtcatcaca gaaaataaaa cagacactcg acgtggtgga acacagctgt
     3361 aatcccagca cctgggaggc agaggcagaa ggattgcaag tgctaagcca gtctgagata
     3421 tctaacaaga tcctgtctca aaaagctaac caataggcac ctatttgagg gtaggggtca
     3481 gttttcctgc atgcgctaag cctggacttg atccagtggt atcctaacca gtggccaatg
     3541 catctgccct gctctgagcc ttccaagttc tgttaaaata gggaagggtc aaactcagga
     3601 ggagtggcag acctgtaaac actacttttc aaagtgaaga ggacagctgt tgatattttc
     3661 tatgtctaat caaaccaaac ggatttaaca atctcatctg tttataaacc tttttaactt
     3721 taggaactta aaaccacagt ctgaaagtct gttaccagct ggtgtcaata tctttctgtc
     3781 tggctgaatt ttatagatta gttttgtttt gttttaaata cctttaagca gcaaaatgtg
     3841 tctaaaatag gtctgttgcc atattgtgaa ttctgtatca tcatttaatg aacttcaatg
     3901 tccttacaga attaaatagt ggcttcataa aatagatcta ccaaaagctg ccatttcagc
     3961 atcttcatat actccttcca cacatgcact cttaagttga tgccctgttg tgtttagaac
     4021 agtttggtaa ccccagtcct caaagccatg tctgatatgg cttaaatgtt ttttttaaaa
     4081 agcaggactt gccttactat ccaacctggc ttcaaacatg ttatcctcca gtctcagact
     4141 cctggatact agaatcatgc atgcactaca ctgccatgct agccttcatc tgcctttgtt
     4201 tcagtatgta gcctaggcta gccttgaact tagagcaatc ctcttgcttc tgcctcacaa
     4261 atgctaagga tacaagtgta tgtcactatg cctgcctttt aggcttactt cttgagtcaa
     4321 gcccagtgag cttgtctgtt tcctgtccac tacacattga tataaacatg gtaagaactg
     4381 ctgactctgg gacaattgtg agaaagcccc cactgctact ttgcctctct tccatatgct
     4441 aaaggtcaga tccccatctg cgagccactt cctcttcagt tccccaacct caggagcccg
     4501 tgggccaatg ctttcaacct cctatatgta gtttcaccct acagcagcct aagctggatt
     4561 cctgactgac ccaggaggct gcatgcatgc tgtctagagc ctcgctcagc acagtgccgg
     4621 cctcatcccc acaccagcca tcgtcactct aatgtatcct ccttccagaa ccacagtctt
     4681 ctcatctagg caagaatgtg acaacactca gcctcgtgaa aatctctggg tgcttatggc
     4741 cctgtcacac aaaagggaat gagtgttgtt tgatagtact tgtatctcaa caattatttt
     4801 taataaaact tgcatttaaa aattcaga
//
