LOCUS       NM_024479               2831 bp    mRNA    linear   ROD 04-AUG-2023
DEFINITION  Mus musculus methyltransferase like 27 (Mettl27), transcript
            variant 1, mRNA.
ACCESSION   NM_024479
VERSION     NM_024479.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2831)
  AUTHORS   Kole C, Berdugo N, Da Silva C, Ait-Ali N, Millet-Puel G, Pagan D,
            Blond F, Poidevin L, Ripp R, Fontaine V, Wincker P, Zack DJ, Sahel
            JA, Poch O and Leveillard T.
  TITLE     Identification of an Alternative Splicing Product of the Otx2 Gene
            Expressed in the Neural Retina and Retinal Pigmented Epithelial
            Cells
  JOURNAL   PLoS One 11 (3), e0150758 (2016)
   PUBMED   26985665
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2831)
  AUTHORS   DeSilva U, Elnitski L, Idol JR, Doyle JL, Gan W, Thomas JW,
            Schwartz S, Dietrich NL, Beckstrom-Sternberg SM, McDowell JC,
            Blakesley RW, Bouffard GG, Thomas PJ, Touchman JW, Miller W and
            Green ED.
  TITLE     Generation and comparative analysis of approximately 3.3 Mb of
            mouse genomic sequence orthologous to the region of human
            chromosome 7q11.23 implicated in Williams syndrome
  JOURNAL   Genome Res 12 (1), 3-15 (2002)
   PUBMED   11779826
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AY354925.2.
            
            On Jul 18, 2004 this sequence version replaced NM_024479.1.
            
            Transcript Variant: This variant (1) differs in the 5' UTR compared
            to variant 3. Variants 1, 3, 4, and 5 all encode the same isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY354925.2, AK132481.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
FEATURES             Location/Qualifiers
     source          1..2831
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 74.89 cM"
     gene            1..2831
                     /gene="Mettl27"
                     /gene_synonym="Wbscr27"
                     /note="methyltransferase like 27"
                     /db_xref="GeneID:79565"
                     /db_xref="MGI:MGI:1933146"
     exon            1..38
                     /gene="Mettl27"
                     /gene_synonym="Wbscr27"
                     /inference="alignment:Splign:2.1.0"
     exon            39..264
                     /gene="Mettl27"
                     /gene_synonym="Wbscr27"
                     /inference="alignment:Splign:2.1.0"
     CDS             142..858
                     /gene="Mettl27"
                     /gene_synonym="Wbscr27"
                     /note="isoform 1 is encoded by transcript variant 1;
                     Williams-Beuren syndrome chromosome region 27 homolog;
                     Williams Beuren syndrome chromosome region 27"
                     /codon_start=1
                     /product="methyltransferase-like protein 27 isoform 1"
                     /protein_id="NP_077799.2"
                     /db_xref="CCDS:CCDS19727.1"
                     /db_xref="GeneID:79565"
                     /db_xref="MGI:MGI:1933146"
                     /translation="MTQEEAGRLPQVLARVGTSHGITDLACKLRFYDDWAPEYDQDVA
                     ALKYRAPRLAVDCLSRAFRGSPHDALILDVACGTGLVAVELQARGFLQVQGVDGSPEM
                     LKQARARGLYHHLSLCTLGQEPLPDPEGTFDAVIIVGALSEGQVPCSAIPELLRVTKP
                     GGLVCLTTRTNPSNLPYKETLEATLDSLERAGVWECLVTQPVDHWELATSEQETGLGT
                     CANDGFISGIIYLYRKQETV"
     exon            265..393
                     /gene="Mettl27"
                     /gene_synonym="Wbscr27"
                     /inference="alignment:Splign:2.1.0"
     exon            394..529
                     /gene="Mettl27"
                     /gene_synonym="Wbscr27"
                     /inference="alignment:Splign:2.1.0"
     exon            530..622
                     /gene="Mettl27"
                     /gene_synonym="Wbscr27"
                     /inference="alignment:Splign:2.1.0"
     exon            623..2803
                     /gene="Mettl27"
                     /gene_synonym="Wbscr27"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cttccctcgg gtctgcctgg agaagggggt tccgcgcgct tgggaccgcg ttggagcact
       61 gataacctcc tccgccgggt gagggaggac ggaagactgt ggaggacctc atcactgggt
      121 ggactctgcc cccgcaggag aatgactcag gaggaggctg ggcggctgcc ccaagtactg
      181 gcccgggtcg gaacctccca cggtatcacc gacctggcct gcaagctccg cttctatgac
      241 gactgggctc cggagtatga ccaggatgtg gctgctttga agtaccgagc cccacgcctt
      301 gctgtggatt gtctcagtcg agcctttcgg ggctcacccc atgatgccct gatcctcgat
      361 gtggcctgtg gcactggcct ggtagctgtg gagctgcagg ctcggggctt cctccaggtg
      421 cagggcgtgg atggaagccc agaaatgctg aagcaggcgc gggcacgtgg cctgtaccac
      481 caccttagcc tctgtaccct gggccaggag ccactgcccg accctgaagg gacctttgac
      541 gcggtgatca ttgtgggtgc cctcagtgag ggacaggtgc cctgcagtgc catacctgag
      601 ctcttaagag tcaccaagcc aggtggactt gtttgtctga ctaccaggac caacccatcc
      661 aaccttccat acaaggagac gctggaagcg accttagact ccctggagcg ggctggagtg
      721 tgggaatgcc tggtgaccca gcctgtggac cactgggagc tagcaacatc agaacaagag
      781 acagggctag gcacctgtgc caatgatggc ttcatctctg gcatcatcta cctttaccgg
      841 aagcaggaga cagtataggg tgagagaggg aggttcagta tcacacccct agttgaccac
      901 tgatcctctg tgtatggtct cagcccagtg tgttttcttg gccttccctg ctctgtctgt
      961 aaaatgggtc caccttccta gccacgcccg ttaggagtac tctgctaggt atagcccaaa
     1021 gggactgaaa agactcctct actttctttg gacccagggc tcgagtgatc accaacagtg
     1081 cttgctctgc aaattgtgag aaaccaagcg gctgtcttca gcatccacat acaaatcaca
     1141 ggtttccaac atgcctgtgt gtaataccac cattgaggtg ggagatgggt gggtcactca
     1201 gcaggtagcc gaccaaaaca ggcatctttg cactcagtga ggcatcctgt cttaaagaga
     1261 taaggcagac cgatggagag tgacagagag gacgaccccc agccccttgc ctgcacatgt
     1321 gcgagcgcat ccttacactc aggtgcacga gccacacaga taccagatac agaaaaaaaa
     1381 taaaaataca acaacacaga gaccagtgtg tactgtaaca cagccaagca ccatcccatc
     1441 cccattttgc aaaagatgtt gaattaggac cagcaagatg gctcagcaga taaagccaca
     1501 cttaaccacc tacctgataa cctgagttgg atcctcagga gccacgtggt aaatggagag
     1561 aaatgacccc tacaagttgt cctttgctgt ctacatagca taaagcacac aaacacacac
     1621 acacagaggc ataggaggta agtaaatgaa ctaaataagg gtgtcaaaca cacactaaac
     1681 aagagcaatg gtgatgaatg cttttactcc tccgagctct caggaggcag aggctggtgg
     1741 atctctgagc tcacaggttt ggccagcctg gcaagatggc tctctgggaa gacttgagtt
     1801 cggtctccag aatgcacatg acaggcgaga accagctcca gcaagttgta ctcagacggc
     1861 cacgaaacac aggcacgcat gcacacagca acaatagaaa gtaaagagac ataaaaataa
     1921 attctaacga caaagaaatg gggtgatctg atttatggga gaatgggaga agcatattca
     1981 taaaattgtg gtttagcctg atctgagatc ttagcctggg gcccccgcga taccaaacta
     2041 acatttccgg cactctggtg tgtccaagaa cctggctcca accagtctga actaggcaag
     2101 gcaatatcca aacccacaca gaaggaagca aagtaaacaa ctgtgaacca tccaacatct
     2161 ggtcccatcc agtcccctcc ccctccccca tcagagatgt tatctgttgt taagctaaca
     2221 ggtgggtaga ctgggttttt ctgagtcacg agggaagcta gggcaaagag ataggtcatt
     2281 tagacctgcc cagaacaaag agctagacct aggttggcct ggtggtacaa gcccagcgcc
     2341 ccagcctccc gagaagccga ggcaggaaga taggaagtcc aaggcctgcc tgggatgcag
     2401 ggtaaaaccc aggccagcct gaaccatttg ccacactcca tttcaaaaag tgagacaaga
     2461 tctagagagg ccggagaaac ggctttgagg ttcagagcac tgactgctct tctggacgac
     2521 ccaggttcac ttcccagcaa ccatatggcg gctcacagct ttctgtaatt ccatttccag
     2581 gggacctgac aaaacaccaa tgtgtgtaaa ataaaactaa ttaaataaat aaataatttg
     2641 aaagatctag agatgtagag cactttggga tcccccagtg aggggctgag ggtatgtgtt
     2701 agcggtagta cggaagccct gccaagaagc cctggagtcc atccctagca caggggctaa
     2761 aaatagatta acaataataa aaaaaaaagt ttgattttct tcaaaaaaaa aaaaaaaaaa
     2821 aaaaaaaaaa a
//
