LOCUS       NM_153562               2847 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Mus musculus methyltransferase like 25B (Mettl25b), mRNA.
ACCESSION   NM_153562
VERSION     NM_153562.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2847)
  AUTHORS   Diez-Roux,G., Banfi,S., Sultan,M., Geffers,L., Anand,S., Rozado,D.,
            Magen,A., Canidio,E., Pagani,M., Peluso,I., Lin-Marq,N., Koch,M.,
            Bilio,M., Cantiello,I., Verde,R., De Masi,C., Bianchi,S.A.,
            Cicchini,J., Perroud,E., Mehmeti,S., Dagand,E., Schrinner,S.,
            Nurnberger,A., Schmidt,K., Metz,K., Zwingmann,C., Brieske,N.,
            Springer,C., Hernandez,A.M., Herzog,S., Grabbe,F., Sieverding,C.,
            Fischer,B., Schrader,K., Brockmeyer,M., Dettmer,S., Helbig,C.,
            Alunni,V., Battaini,M.A., Mura,C., Henrichsen,C.N.,
            Garcia-Lopez,R., Echevarria,D., Puelles,E., Garcia-Calero,E.,
            Kruse,S., Uhr,M., Kauck,C., Feng,G., Milyaev,N., Ong,C.K.,
            Kumar,L., Lam,M., Semple,C.A., Gyenesei,A., Mundlos,S., Radelof,U.,
            Lehrach,H., Sarmientos,P., Reymond,A., Davidson,D.R., Dolle,P.,
            Antonarakis,S.E., Yaspo,M.L., Martinez,S., Baldock,R.A., Eichele,G.
            and Ballabio,A.
  TITLE     A high-resolution anatomical atlas of the transcriptome in the
            mouse embryo
  JOURNAL   PLoS Biol 9 (1), e1000582 (2011)
   PUBMED   21267068
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB871494.1, AK035389.1, BY035934.1, AI592533.1, AA611348.1,
            BB684061.1 and BY617418.1.
            
            On Oct 1, 2009 this sequence version replaced NM_153562.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK035389.1, SRR17784645.966967.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-51                BB871494.1         6-56
            52-359              AK035389.1         4-311
            360-436             BY035934.1         310-386
            437-1286            AK035389.1         389-1238
            1287-1585           AI592533.1         278-576
            1586-2543           AK035389.1         1538-2495
            2544-2671           AA611348.1         1-128               c
            2672-2842           BB684061.1         232-402
            2843-2847           BY617418.1         382-386
FEATURES             Location/Qualifiers
     source          1..2847
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 38.78 cM"
     gene            1..2847
                     /gene="Mettl25b"
                     /gene_synonym="Rrnad1"
                     /note="methyltransferase like 25B"
                     /db_xref="GeneID:229503"
                     /db_xref="MGI:MGI:2387197"
     exon            1..340
                     /gene="Mettl25b"
                     /gene_synonym="Rrnad1"
                     /inference="alignment:Splign:2.1.0"
     CDS             230..1657
                     /gene="Mettl25b"
                     /gene_synonym="Rrnad1"
                     /note="protein RRNAD1; ribosomal RNA adenine dimethylase
                     domain containing 1"
                     /codon_start=1
                     /product="methyltransferase-like protein 25B"
                     /protein_id="NP_705790.3"
                     /db_xref="CCDS:CCDS17458.1"
                     /db_xref="GeneID:229503"
                     /db_xref="MGI:MGI:2387197"
                     /translation="MRGVSAHGLSHEERRQLAVDLTRVLAHYRSILDAYIIEFFTDSL
                     WGTLPHSWQEALDGLNPPQLATLLLGMPRDGEEMRYRSVWPLTLLALKSTACALAFTR
                     TPGFHTPSEFLENPSQSSRLTAPFRKHVKPKKQHEIRRLGELVKKLSDLTGCTQVVDV
                     GSGQGHLSRFMSLGLGLMVKSLEGNQRLVKRAQHLDQELLKALDKMEKRHPKMVQRGP
                     RHRPHHVVQWVSPTTLCEELLLPLERPGQSSARLLLTGLHACGDLSVALLRHFCCCPE
                     VVALASVGCCYMKLSDPGSYPLSQWIAGLPGHELPYRLREGACHALEDYAERLHKAEP
                     GLQTHCFRAALETVIRQVCPELRRPGVQGIPRVHELKIEEYVKQGLKRVGLDPQLPLD
                     LAALQAHQAQENRVVAFFSLALLLAPLVETLILLDRMLYLQEQGFYAELLPIFSPELS
                     PRNLVLVATKTPLGQAFSTLETEDN"
     exon            341..465
                     /gene="Mettl25b"
                     /gene_synonym="Rrnad1"
                     /inference="alignment:Splign:2.1.0"
     exon            466..658
                     /gene="Mettl25b"
                     /gene_synonym="Rrnad1"
                     /inference="alignment:Splign:2.1.0"
     exon            659..721
                     /gene="Mettl25b"
                     /gene_synonym="Rrnad1"
                     /inference="alignment:Splign:2.1.0"
     exon            722..865
                     /gene="Mettl25b"
                     /gene_synonym="Rrnad1"
                     /inference="alignment:Splign:2.1.0"
     exon            866..1350
                     /gene="Mettl25b"
                     /gene_synonym="Rrnad1"
                     /inference="alignment:Splign:2.1.0"
     exon            1351..1535
                     /gene="Mettl25b"
                     /gene_synonym="Rrnad1"
                     /inference="alignment:Splign:2.1.0"
     exon            1536..2847
                     /gene="Mettl25b"
                     /gene_synonym="Rrnad1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1759..1764
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mettl25b"
                     /gene_synonym="Rrnad1"
                     /note="hexamer: TATAAA"
     polyA_site      1790
                     /gene="Mettl25b"
                     /gene_synonym="Rrnad1"
                     /note="major polyA site"
     regulatory      2110..2115
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mettl25b"
                     /gene_synonym="Rrnad1"
                     /note="hexamer: AATAAA"
     polyA_site      2132
                     /gene="Mettl25b"
                     /gene_synonym="Rrnad1"
     regulatory      2828..2833
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mettl25b"
                     /gene_synonym="Rrnad1"
                     /note="hexamer: AATAAA"
     polyA_site      2847
                     /gene="Mettl25b"
                     /gene_synonym="Rrnad1"
ORIGIN      
        1 gcgcaaatgg cttggcccag tggaagtcgt gacgttgggc aagtgcgcct tgttctaagg
       61 atttgtaata ggacgggatc gccctgagag gtgtcgtcgg gcgggttcgg agttcttgct
      121 ttgcgtcggg cgtgcagaat tgagtccggt ttgggttgca tggtttcgtg gtaccgacct
      181 tgtgtctcct cacctcctcc ctccttgcac cgacatttca cgccacagga tgcggggcgt
      241 ttcagcccat ggcctctcgc atgaggagag aaggcaactg gctgtggacc tcacccgcgt
      301 cctagctcac taccgttcca tcctggacgc ctacatcatc gaatttttca cggacagcct
      361 gtggggcaca ctcccccact catggcaaga agcactggat ggactgaacc caccacagct
      421 ggccaccctg ctgctgggga tgccgaggga cggggaggaa atgaggtaca ggtctgtgtg
      481 gccactcacc ctgctggccc tgaagtccac agcttgtgcc ctcgccttta cccggacacc
      541 tggctttcac accccatcag agttcctgga gaaccccagc cagagctccc gactaacagc
      601 tccttttcgg aaacatgtca agcccaagaa gcagcatgag atccggaggc tgggagagtt
      661 ggtgaagaag cttagcgatc tcactggctg cacccaagtt gtggatgtgg gctcaggcca
      721 gggccacctc tcccgcttca tgtctctggg gctggggctg atggtgaaga gccttgaagg
      781 gaatcagagg ctggtaaaga gagctcagca tctagaccag gagctcctga aggctctgga
      841 caaaatggag aagaggcacc caaagatggt gcaaagaggc cctcgccacc ggccccacca
      901 cgtggttcag tgggtcagcc ccacaactct gtgtgaggag cttctgcttc ctctggagag
      961 accaggccag agtagtgcac gtctgctgct cacaggcctt catgcttgtg gggatcttag
     1021 tgttgccttg ctaagacact tctgctgctg tcctgaagtg gtggccctgg cctcggtagg
     1081 ctgctgctac atgaaactca gtgaccctgg cagctaccca ctgagtcagt ggatagctgg
     1141 gctgcctggc catgaactac cctacaggct ccgggagggt gcctgccatg ctctggagga
     1201 ctatgcggag agattacata aagcagagcc tggcctgcaa acacactgct tccgtgcagc
     1261 actggagaca gtcatccgac aagtctgccc tgagcttcgg aggcctggtg tgcaaggaat
     1321 ccccagggtc catgaactca agattgaaga atatgtgaaa caagggttaa agcgagtggg
     1381 tctggacccc cagctgcctt tggatctggc tgccctccag gcccaccagg cccaagagaa
     1441 tcgtgtggtg gccttcttca gcttggccct cctgctggcc ccactggtag agacattgat
     1501 tctactggac cggatgctct atcttcagga gcaaggcttc tatgctgagc tcctgcccat
     1561 cttcagccct gaactctctc ccagaaatct ggttctggtg gccaccaaga cgcccctggg
     1621 tcaggccttc tccactcttg agactgaaga caactgacag tctgaaacca ccagtgccaa
     1681 tatggctgga taccataact tcagatttgt accctttctt tctcttcttg tgtaaagtaa
     1741 tactgtgtaa tttttattta taaagctttt aagacttctg tttctataaa taccatgtaa
     1801 tttttatttc ttaaaactct taaaactcct atttctgtaa atagggaaaa gaacagaggg
     1861 gccttcttgc tcccatctcc aaacatcagg acctatccct gggaaggcta gcacctaccc
     1921 agtctatcct gacaagaaga aaagctgcac tgtgcctgag ctccccaaaa tgcaagcact
     1981 tgggagaggc agaggggtag tgtggacaac ggctgctctc aagtctcttt attggtgttt
     2041 tagaaaaaag gcctctacca tcaaggtgaa aactggacag gcagaagcag cactctgagg
     2101 ctcaatacca ataaactttc ttgaatcttc gagtctcctg gatccccatg gcctccatca
     2161 catcttcttc taatgtcttt agtcggggca cataagttct ttcaagagca tcttccactg
     2221 atgtgtcctt ggggccatct gttgaatcaa agtgtttgcc aactctctat ttcttcaact
     2281 gccctacaac caagccctgc ccacattcct agcccagcaa cttattagct tttcctctca
     2341 aacctcacag ccctacgctc ttcctgccca tcctcaactt accagtccat gtttcaggga
     2401 caatgccatc tgctctagga aattcaggtt tggggataat tctgccagat cttgtagaga
     2461 ctcgaacacg ttctcctgcc tcagtaaatc tccactggat ctcagtgggt ttcctggtgg
     2521 gtaagaataa aaaaaaaaaa atctagtttg gagcctgtgt caccctgcaa cccaaaagtg
     2581 aaggcagtgg ttgagaacct ctgggatttt gtctgtatca gggttactga cagaattgtg
     2641 tacaagaaac agacctctgg ggggctggtg agatcctcag tgggtaagtg cattgactgc
     2701 ccttccgaag gtcttgagtt ccaatcccca gtaaccatat ggtggctcaa aaccacctat
     2761 aatgagacct gatgccctct tctggggtgt ctgaagacag ctacagtgta cttacatata
     2821 ataaataaat aaacatcttt aaaacaa
//
