LOCUS       NM_177793               1529 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus methyltransferase like 24 (Mettl24), mRNA.
ACCESSION   NM_177793
VERSION     NM_177793.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1529)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1529)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK033488.1.
            
            On Apr 6, 2007 this sequence version replaced NM_177793.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK033488.1, BC147316.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849377
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1529              AK033488.1         2-1530
FEATURES             Location/Qualifiers
     source          1..1529
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 22.02 cM"
     gene            1..1529
                     /gene="Mettl24"
                     /gene_synonym="9030224M15Rik"
                     /note="methyltransferase like 24"
                     /db_xref="GeneID:327747"
                     /db_xref="MGI:MGI:3045338"
     exon            1..383
                     /gene="Mettl24"
                     /gene_synonym="9030224M15Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             75..1166
                     /gene="Mettl24"
                     /gene_synonym="9030224M15Rik"
                     /note="UPF0624 protein C6orf186 homolog;
                     methyltransferase-like protein 24; probable
                     methyltransferase-like protein 24"
                     /codon_start=1
                     /product="probable methyltransferase-like protein 24
                     precursor"
                     /protein_id="NP_808461.1"
                     /db_xref="CCDS:CCDS23799.1"
                     /db_xref="GeneID:327747"
                     /db_xref="MGI:MGI:3045338"
                     /translation="MATVKPPGRGCGALPRWLLGAALLLGLRLCMELRHAGSGPPGRG
                     DSPGPPRTHLLSAPGSPRGARRRQVTYVRSGRRVLPRGGGSTTSPEPSCCAQGGLLRR
                     KGSRWHIELQPWAGPSRSLDEEASRFLSYISTTQIACDHMGTDSLATDSSPAPKPWLV
                     CLDDRFGLAHQIRSKRCRLYSLGLGSDDTHFEVSMANGGCEVHRFDPSVKSAHVLERQ
                     GLWHHRLSIDWRDPHPAVAAQKPHGNTRKLGSILNEFGHHKIDVLKADLESAEWKVLE
                     NLILEDVLEQIGQLVFEIHLHWPGFEVSGSESGVVRFWYSLLKELERKHFRLFHTYKD
                     LTKPQLFLKKDLFNASSCYTLSWVNTKWR"
     exon            384..482
                     /gene="Mettl24"
                     /gene_synonym="9030224M15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            483..622
                     /gene="Mettl24"
                     /gene_synonym="9030224M15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            623..851
                     /gene="Mettl24"
                     /gene_synonym="9030224M15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            852..1529
                     /gene="Mettl24"
                     /gene_synonym="9030224M15Rik"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1529
                     /gene="Mettl24"
                     /gene_synonym="9030224M15Rik"
                     /note="putative"
ORIGIN      
        1 gggaacgctt ctctgcaggc ggctgggagc tgagggtggg acccagagca cagccggagg
       61 tcgaggtccc cgccatggcc actgtcaagc ctcccgggcg tggttgtgga gccctgcccc
      121 ggtggctgct cggtgccgcg ctgcttctgg gcctacggct ttgcatggag ttgcgccacg
      181 cgggctcggg acccccgggc cgcggcgatt ccccagggcc accccggaca cacctactgt
      241 cggcgcccgg ctccccacgc ggagccagaa ggaggcaggt gacctacgtg cgcagtgggc
      301 gccgagtgct gccccggggt ggcgggagca cgacgtcccc agagccgagc tgctgtgccc
      361 agggcgggct tctccgcagg aagggttccc gatggcacat agagctccag ccatgggcag
      421 gcccttctcg gtccctggat gaagaggcct caaggttcct gagctacatc agtaccactc
      481 agattgcatg cgatcacatg ggtacagaca gcttggctac tgactccagc cctgcaccga
      541 agccctggct ggtgtgtctt gatgacaggt ttggcttagc tcatcaaatc cgcagcaagc
      601 ggtgccgcct ctactcttta gggctgggga gtgatgacac acactttgag gtgagcatgg
      661 ccaacggtgg atgtgaagtg catcgttttg atccgagtgt caagtcagcc catgttctgg
      721 agcggcaggg cctctggcat caccgcttgt ccatcgattg gcgggatccg catccagccg
      781 tggctgctca gaagccgcac ggcaacacca gaaaactggg aagcattctg aatgaatttg
      841 ggcaccacaa gatcgacgtt ctcaaggcag atctggaaag tgcggagtgg aaagttctgg
      901 aaaaccttat tctggaggat gttcttgagc agatcggcca gctcgtcttc gagattcatc
      961 ttcactggcc cggttttgag gttagcggca gcgagagcgg cgtggtgcgc ttttggtaca
     1021 gcctcctgaa ggagttggag cggaagcact tccgactttt tcacacctat aaagacttaa
     1081 cgaaacctca gcttttcctg aagaaggacc ttttcaacgc tagcagctgt tataccttga
     1141 gttgggtgaa tacaaagtgg aggtgagatg aagcctccgg cacgtacagc acaggtggat
     1201 acgtccgtcc ttccagtcat ggagttacgt ctccagtctc ccccggcttg tcacttgctt
     1261 gaagcagggc ttgggtgatt gtctcctgaa gtacgtaatg aagccttgag cttggccttg
     1321 agcttggcga gtgacagtga catgggtgaa taccttcact tgcccagact aagaccttcg
     1381 ccttcttagc cttggacaga gtgggggtgt gcccctttac tgtccctagg atgtacaaat
     1441 accctgcgca ggccagcttg tggctttctt aaaatccatt atgtatctac agctaatgaa
     1501 tctacattaa aatgaaattt tattatttc
//
