LOCUS       NM_146247               1350 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus methyltransferase 22, Kin17 lysine (Mettl22),
            transcript variant 1, mRNA.
ACCESSION   NM_146247 XM_979618
VERSION     NM_146247.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1350)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1350)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC123851.4.
            
            On Feb 28, 2023 this sequence version replaced NM_146247.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC024814.1, AK136614.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-86                AC123851.4         109824-109909       c
            87-222              AC123851.4         106723-106858       c
            223-585             AC123851.4         102360-102722       c
            586-626             AC123851.4         98522-98562         c
            627-771             AC123851.4         98289-98433         c
            772-843             AC123851.4         96356-96427         c
            844-897             AC123851.4         95816-95869         c
            898-978             AC123851.4         94744-94824         c
            979-1081            AC123851.4         93228-93330         c
            1082-1250           AC123851.4         91862-92030         c
            1251-1350           AC123851.4         90488-90587         c
FEATURES             Location/Qualifiers
     source          1..1350
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 3.97 cM"
     gene            1..1350
                     /gene="Mettl22"
                     /note="methyltransferase 22, Kin17 lysine"
                     /db_xref="GeneID:239706"
                     /db_xref="MGI:MGI:2384301"
     exon            1..86
                     /gene="Mettl22"
                     /inference="alignment:Splign:2.1.0"
     exon            87..222
                     /gene="Mettl22"
                     /inference="alignment:Splign:2.1.0"
     exon            223..585
                     /gene="Mettl22"
                     /inference="alignment:Splign:2.1.0"
     exon            586..626
                     /gene="Mettl22"
                     /inference="alignment:Splign:2.1.0"
     exon            627..771
                     /gene="Mettl22"
                     /inference="alignment:Splign:2.1.0"
     exon            772..843
                     /gene="Mettl22"
                     /inference="alignment:Splign:2.1.0"
     exon            844..897
                     /gene="Mettl22"
                     /inference="alignment:Splign:2.1.0"
     exon            898..978
                     /gene="Mettl22"
                     /inference="alignment:Splign:2.1.0"
     exon            979..1081
                     /gene="Mettl22"
                     /inference="alignment:Splign:2.1.0"
     exon            1082..1250
                     /gene="Mettl22"
                     /inference="alignment:Splign:2.1.0"
     exon            1251..1350
                     /gene="Mettl22"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1329..1334
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mettl22"
                     /note="hexamer: AATAAA"
     polyA_site      1350
                     /gene="Mettl22"
                     /note="major polyA site"
ORIGIN      
        1 gcgcctgcgc aagctgtccg tcatggcggc ttcctgagcc ccatggctag ggttccgcgt
       61 gggacttcag accagtgtca tggcgggtgc atcccaggaa tagcatgggc ccagccatgg
      121 acgaggtcac cttcaaaagt gacactgtgc tgtcagatgt ccacctgtac acccccaacc
      181 agaggcacct catggtgcgg ctgaatggca tggggcagcc agtcttcctg tcccagttca
      241 agctcttgtg gagtcgggac tcttggacag actcgggggc tgaggacagt ggtcccacag
      301 acgtctccac agaggagatg ccccctgctg ggtcaggaag tggccacagt catgaggatt
      361 tgtccctcca ggctggggat gacaacacca tccaggaagg gttgagtgtt cccctggacg
      421 aggatgggga cctggatgtg gtacgaaggc cacgggctgc ttctgatccc aacccggcag
      481 agcccgcaag agacaaggta caccccacga ttctagcaca ggaggaagat gacctcgtgg
      541 gagaccagga gtacgagagc tgcccccaca gcatcatcaa aatagagcac accatggcca
      601 cgcccctgga ggatgtaggc aagcaggtgt ggcggggtgc cctactcctg gcagactata
      661 tcctgttccg aagagacctc ttccagggat gcaccgtgct ggagcttggg gcaggcacag
      721 ggcttgccag catcgtggca gccacgatgg cacacaccgt ttattgtaca gatgtcggca
      781 cagacctcct ggccatgtgc caacgaaacg ttgccctcaa cagccacctg actgccactg
      841 gaggtggcgt ggttaaggtc aaggagctgg actggctgaa ggacaacctc tgcacagatc
      901 ccaaagcccc cttcagctgg tcagaagaag aaatcgctga cctgtatgac cacaccactg
      961 tgctgcttgc agccgaagtg ttctacgatg atgacttaac caacgctctg tttaacacac
     1021 tttcccgact ggtccacaga ctgaaaaatg cctgcaccgc catcttctca gtggaaaaaa
     1081 ggttcaactt cacactgaga cacttggacg tcacgtgtga agcctacgat cacttccgtg
     1141 cctccctgga ctcattggag aagctggccg atggcaggct gcgcttcatg gtggagcctg
     1201 tggaggcctc cttcccgcag ctgctcgtct atgaacgcat ccggcagctg gagctctgga
     1261 agatagttgt ggaaccagca gcgtgagtcg cctctgtgac ctcttgacta atattttaac
     1321 gcatttcgaa taaagacaaa ccctcagcca
//
