LOCUS       NM_172694               3062 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus multiple EGF-like-domains 9 (Megf9), mRNA.
ACCESSION   NM_172694
VERSION     NM_172694.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3062)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3062)
  AUTHORS   Shalom-Barak,T., Zhang,X., Chu,T., Timothy Schaiff,W., Reddy,J.K.,
            Xu,J., Sadovsky,Y. and Barak,Y.
  TITLE     Placental PPARgamma regulates spatiotemporally diverse genes and a
            unique metabolic network
  JOURNAL   Dev Biol 372 (1), 143-155 (2012)
   PUBMED   22967998
REFERENCE   3  (bases 1 to 3062)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
REFERENCE   4  (bases 1 to 3062)
  AUTHORS   Brandt-Bohne,U., Keene,D.R., White,F.A. and Koch,M.
  TITLE     MEGF9: a novel transmembrane protein with a strong and
            developmentally regulated expression in the nervous system
  JOURNAL   Biochem J 401 (2), 447-457 (2007)
   PUBMED   16981854
  REMARK    GeneRIF: MEGF9 represents a novel putative receptor, expressed in
            neuronal and non-neuronal tissues, that is regulated during
            development and could function as a guidance or signalling
            molecule.
REFERENCE   5  (bases 1 to 3062)
  AUTHORS   Kenney-Hunt,J.P., Vaughn,T.T., Pletscher,L.S., Peripato,A.,
            Routman,E., Cothran,K., Durand,D., Norgard,E., Perel,C. and
            Cheverud,J.M.
  TITLE     Quantitative trait loci for body size components in mice
  JOURNAL   Mamm Genome 17 (6), 526-537 (2006)
   PUBMED   16783635
REFERENCE   6  (bases 1 to 3062)
  AUTHORS   Corbo,J.C. and Cepko,C.L.
  TITLE     A hybrid photoreceptor expressing both rod and cone genes in a
            mouse model of enhanced S-cone syndrome
  JOURNAL   PLoS Genet 1 (2), e11 (2005)
   PUBMED   16110338
  REMARK    Erratum:[PLoS Genet. 2008 Jan;4(1):e18]
REFERENCE   7  (bases 1 to 3062)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
REFERENCE   8  (bases 1 to 3062)
  AUTHORS   Lemon,W.J., Bernert,H., Sun,H., Wang,Y. and You,M.
  TITLE     Identification of candidate lung cancer susceptibility genes in
            mouse using oligonucleotide arrays
  JOURNAL   J Med Genet 39 (9), 644-655 (2002)
   PUBMED   12205107
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK035987.1.
            
            On Apr 5, 2007 this sequence version replaced NM_172694.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK035987.1, SRR1660821.96216.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3062              AK035987.1         2-3063
FEATURES             Location/Qualifiers
     source          1..3062
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 35.92 cM"
     gene            1..3062
                     /gene="Megf9"
                     /gene_synonym="4933405H16Rik; 9630025C07; Egfl5;
                     mKIAA0818"
                     /note="multiple EGF-like-domains 9"
                     /db_xref="GeneID:230316"
                     /db_xref="MGI:MGI:1918264"
     exon            1..701
                     /gene="Megf9"
                     /gene_synonym="4933405H16Rik; 9630025C07; Egfl5;
                     mKIAA0818"
                     /inference="alignment:Splign:2.1.0"
     CDS             107..1909
                     /gene="Megf9"
                     /gene_synonym="4933405H16Rik; 9630025C07; Egfl5;
                     mKIAA0818"
                     /note="EGF-like-domain, multiple 5; multiple epidermal
                     growth factor-like domains protein 9; EGF-like protein 5;
                     multiple EGF-like domains protein 9; epidermal growth
                     factor-like protein 5"
                     /codon_start=1
                     /product="multiple epidermal growth factor-like domains
                     protein 9 precursor"
                     /protein_id="NP_766282.1"
                     /db_xref="CCDS:CCDS18273.1"
                     /db_xref="GeneID:230316"
                     /db_xref="MGI:MGI:1918264"
                     /translation="MNGGAERAMRSLPSLGGLALLCCAAAAAASTASAGNVTGGGGAE
                     GQVVPSPSPGLRDQASSPFPKTAAPTAQAPRTGPPRTTVRKTGATTPSAGSPEIIPPL
                     RTSAQPAATPFPALDLSPATPSEDGHTPTTESPPSRPAPTTLASTVGQPPTTSVVTTA
                     QASSTPGTPTAESPDRSSNSSGVPPTAPVTEAPTSPPPEHMCNCSEVGSLDVKRCNQT
                     TGQCDCHVGYQGLHCDTCKEGFYLNHTVGLCLPCHCSPHGAVSILCNSSGNCQCKVGV
                     TGSMCDKCQDGHYGFGKTGCLPCQCNNRSDSCDVHTGACLNCQENSKGEHCEECKEGF
                     YPSPDAAKQCHRCPCSAVTSTGNCTIESGELEPTCDQCKDGYTGQNCNKCENGYYNSD
                     SICTQCECHGHVDPIKTPKICKPESGECINCLHNTTGFWCEKCLEGYVRDLQRNCIKQ
                     EVIVPTPEGSTILVSNASLTTSVPTPVINSTFAPTTLQTIFAVSSSENSTSALADVSW
                     TQFNIIILTVIIIVVVLLMGFVGAVYMYREYQNRKLNAPFWTIELKEDNISFSSYHDS
                     IPNADVSGLLEDDANEVAPNGQLTLTTPIHNYKA"
     exon            702..903
                     /gene="Megf9"
                     /gene_synonym="4933405H16Rik; 9630025C07; Egfl5;
                     mKIAA0818"
                     /inference="alignment:Splign:2.1.0"
     exon            904..1043
                     /gene="Megf9"
                     /gene_synonym="4933405H16Rik; 9630025C07; Egfl5;
                     mKIAA0818"
                     /inference="alignment:Splign:2.1.0"
     exon            1044..1187
                     /gene="Megf9"
                     /gene_synonym="4933405H16Rik; 9630025C07; Egfl5;
                     mKIAA0818"
                     /inference="alignment:Splign:2.1.0"
     exon            1188..1457
                     /gene="Megf9"
                     /gene_synonym="4933405H16Rik; 9630025C07; Egfl5;
                     mKIAA0818"
                     /inference="alignment:Splign:2.1.0"
     exon            1458..3062
                     /gene="Megf9"
                     /gene_synonym="4933405H16Rik; 9630025C07; Egfl5;
                     mKIAA0818"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2373..2378
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Megf9"
                     /gene_synonym="4933405H16Rik; 9630025C07; Egfl5;
                     mKIAA0818"
                     /note="hexamer: AATAAA"
     polyA_site      2404
                     /gene="Megf9"
                     /gene_synonym="4933405H16Rik; 9630025C07; Egfl5;
                     mKIAA0818"
                     /note="major polyA site"
ORIGIN      
        1 agagggaggt ggcgatggtg ctcttggtgg cggcagcggc ggcaacgctt tccttggtcg
       61 gacggcaggg aggagaagat gactgaccga tcgactggat gaatgaatga atggcggagc
      121 cgagcgcgcc atgaggagcc tgccgagcct gggcggcctc gccctgttgt gctgcgcggc
      181 cgccgcagcc gcttccacag cctcggcagg gaatgtcacc ggtggcggcg gggccgaggg
      241 gcaggtggtc ccgtcgccca gcccggggct tcgggaccaa gccagcagcc ccttccctaa
      301 gaccgcggct cccaccgcgc aggccccgcg gaccggtccc ccgcgcacca cagtccgcaa
      361 aaccggggct acaaccccgt cagccggctc cccggagatc attcctcctc ttcgcaccag
      421 cgcacaaccc gctgccaccc ccttcccggc tctggacctc tcgcccgcca ccccttcgga
      481 ggacggacac actcccacca cggaatcacc accctccaga cccgcgccca ccacccttgc
      541 gagcacagtt ggccagccgc cgaccacctc tgtagtcacc accgctcagg cttccagcac
      601 tccagggacc ccaactgccg agtccccgga cagaagcagc aacagtagcg gagtcccgcc
      661 caccgcacct gtcaccgaag cccctacttc tcctccccca gagcatatgt gtaactgttc
      721 tgaggttgga agtttggatg taaagcgctg caaccagacc acagggcagt gtgattgtca
      781 tgtgggttat cagggtcttc actgtgacac ctgcaaagag ggcttttacc tgaatcacac
      841 tgttggtctc tgcctgccat gtcactgcag tccacatgga gctgttagca tcctctgtaa
      901 cagttctggg aattgccaat gcaaagtggg tgtcaccggc tccatgtgtg acaaatgcca
      961 agatggacat tatggctttg gtaagacagg ctgcttgcct tgccagtgca acaaccggtc
     1021 tgatagttgt gatgttcaca caggtgcttg tctaaactgc caggaaaata gtaaagggga
     1081 acactgtgaa gaatgcaaag aaggatttta tccgagtcct gatgccgcaa aacagtgcca
     1141 tcgctgcccg tgttccgcag tgacttctac aggcaattgc accattgaat ctggagagtt
     1201 ggagcctaca tgtgaccaat gtaaagatgg ttacacaggc cagaactgca ataaatgtga
     1261 aaatggctat tacaattctg acagcatctg cacacagtgc gaatgtcatg gccatgtgga
     1321 cccaattaaa actccaaaga tttgcaagcc tgagagtggt gagtgcatca actgccttca
     1381 taacaccact gggttctggt gcgagaaatg cctagaaggc tatgttcgag atcttcagag
     1441 aaactgcatc aagcaagaag ttattgttcc aactcctgaa ggttctacca ttttggtttc
     1501 caatgcctct ttgaccacat cagtgcccac ccctgttata aatagtactt ttgcccccac
     1561 aaccctgcag actatctttg cagtaagctc ttctgaaaac agcacctcag ctcttgctga
     1621 tgtatcatgg acccagttta acatcatcat tttgacagtc atcatcattg tggtagtgct
     1681 gctaatggga tttgtaggag ctgtgtacat gtaccgagag taccaaaatc ggaaactcaa
     1741 tgctcccttt tggaccatcg agctgaaaga agacaatatc agtttcagca gctaccatga
     1801 cagcatcccc aatgcagatg tgtcgggatt gttagaggac gatgccaatg aagtggctcc
     1861 caatgggcag ctgaccctga caacacctat tcataactac aaagcctgag aagctgagtt
     1921 gtcctcctgg attgtcagaa aacagtgctc acttaaacag cacctgacct ctggctgcac
     1981 agagcctagg tagagtttgt tgagaaaggt attgtgcaaa tgttcaggta caaactgtag
     2041 tgcgcttagc ctgtctgttg ctcttaattc ccccatgaag atctgaagca ctcatcatcg
     2101 aggacttgaa gtaaagtata tttttgtagc aaaccacatg tatatatgga aaggctgaat
     2161 cccacagagc agcctaagtc tacctggcct ctcaaaggac tgctcggaaa gtgttcacct
     2221 caccagatgt gatagaatgt tgatgtggag gggaaagact gatggaagaa ttcatctcca
     2281 ctttggaaac atattttata aaagagaggc agggattgtg ttcattttac tgtactaaga
     2341 gatgtaactt aggaagagat gatatctagg ctaataaaaa aaatcttggt tgtgtgtaga
     2401 ctaagaaagg tgccaagaag ttctgtagaa gggcttggct ttccttctaa gagtctcctt
     2461 caaaaatgga gttaaagcac aggataagct tccatggtga gggtaggcac agcaggcaga
     2521 gagcagaaag ctgatggtct cctcaaagag gttcctgcct ctaaagaaac aaggtgtaca
     2581 taattaatgt agcattatct ggtcaacatt gtacttgtat ctatttgtaa aaaatcatgt
     2641 cctattttat catctagact ttatctgtat agcagttaat ggtgttgtaa aaagaagata
     2701 tgggaacttg gttaaaatac tgtaaaatag gtgacaatat tgctagagct gggactctgg
     2761 tgagcatcag tcattttagt ccctatttgg acactgttga aattgataag aggtcaaatg
     2821 tttctaatct ttcctctctc aacctagagt catatgctct ttgacttacc atagattcaa
     2881 gcaatagatt ttgaagtctg caattgcgaa actggaacac aggctgcatt ctccagacac
     2941 acctaattag ccactctgtt ttacactgct cagtgtaaac tcctcaggaa aagacttctt
     3001 tcctgaatgt aaaagacagt cttccaaagg acagaaaatt taaattaaaa agaaaagcca
     3061 tc
//
