LOCUS       NM_026042               2178 bp    mRNA    linear   ROD 18-JUN-2024
DEFINITION  Mus musculus mediator complex subunit 29 (Med29), mRNA.
ACCESSION   NM_026042 XM_992582
VERSION     NM_026042.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2178)
  AUTHORS   Kolonay,D.W., Sattler,K.M., Strawser,C., Rafael-Fortney,J.,
            Mihaylova,M.M., Miller,K.E., Lepper,C. and Baskin,K.K.
  TITLE     Temporal regulation of the Mediator complex during muscle
            proliferation, differentiation, regeneration, aging, and disease
  JOURNAL   Front Cell Dev Biol 12, 1331563 (2024)
   PUBMED   38690566
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2178)
  AUTHORS   Tan,C., Zhu,S., Chen,Z., Liu,C., Li,Y.E., Zhu,M., Zhang,Z.,
            Zhang,Z., Zhang,L., Gu,Y., Liang,Z., Boyer,T.G., Ouyang,K.,
            Evans,S.M. and Fang,X.
  TITLE     Mediator complex proximal Tail subunit MED30 is critical for
            Mediator core stability and cardiomyocyte transcriptional network
  JOURNAL   PLoS Genet 17 (9), e1009785 (2021)
   PUBMED   34506481
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2178)
  AUTHORS   Tomomori-Sato,C., Sato,S., Parmely,T.J., Banks,C.A., Sorokina,I.,
            Florens,L., Zybailov,B., Washburn,M.P., Brower,C.S., Conaway,R.C.
            and Conaway,J.W.
  TITLE     A mammalian mediator subunit that shares properties with
            Saccharomyces cerevisiae mediator subunit Cse2
  JOURNAL   J Biol Chem 279 (7), 5846-5851 (2004)
   PUBMED   14638676
REFERENCE   4  (bases 1 to 2178)
  AUTHORS   Mittler,G., Kremmer,E., Timmers,H.T. and Meisterernst,M.
  TITLE     Novel critical role of a human Mediator complex for basal RNA
            polymerase II transcription
  JOURNAL   EMBO Rep 2 (9), 808-813 (2001)
   PUBMED   11559591
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC149606.6.
            
            On Jan 23, 2023 this sequence version replaced NM_026042.3.
            
            Sequence Note:.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.2619945.1,
                                           SRR17253011.5182882.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-251               AC149606.6         120643-120893
            252-310             AC149606.6         122196-122254
            311-395             AC149606.6         122448-122532
            396-2178            AC149606.6         126320-128102
FEATURES             Location/Qualifiers
     source          1..2178
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 16.72 cM"
     gene            1..2178
                     /gene="Med29"
                     /gene_synonym="2810405O22Rik; Ixl"
                     /note="mediator complex subunit 29"
                     /db_xref="GeneID:67224"
                     /db_xref="MGI:MGI:1914474"
     exon            1..251
                     /gene="Med29"
                     /gene_synonym="2810405O22Rik; Ixl"
                     /inference="alignment:Splign:2.1.0"
     CDS             39..638
                     /gene="Med29"
                     /gene_synonym="2810405O22Rik; Ixl"
                     /note="intersex-like protein"
                     /codon_start=1
                     /product="mediator of RNA polymerase II transcription
                     subunit 29"
                     /protein_id="NP_080318.2"
                     /db_xref="CCDS:CCDS21042.1"
                     /db_xref="GeneID:67224"
                     /db_xref="MGI:MGI:1914474"
                     /translation="MAAPQPQAAAVSSASGVSGPGSAGGPGPQQQPQPTQLVGSAQSG
                     LLQQQQQDFDPVQRYKMLIPQLKESLQTLMKVAAQNLIQNTNIDNGQKSSDAPLQRFD
                     KCLEEFYALCDQLELCLRLAHECLSQSCDSAKHSPTLVPTATKPDAVQPDSLPYPQYL
                     AVIKAQITCAKDIHTALLDCANKVTGKTTAPSTGPGGSL"
     exon            252..310
                     /gene="Med29"
                     /gene_synonym="2810405O22Rik; Ixl"
                     /inference="alignment:Splign:2.1.0"
     exon            311..395
                     /gene="Med29"
                     /gene_synonym="2810405O22Rik; Ixl"
                     /inference="alignment:Splign:2.1.0"
     exon            396..2178
                     /gene="Med29"
                     /gene_synonym="2810405O22Rik; Ixl"
                     /inference="alignment:Splign:2.1.0"
     regulatory      661..666
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Med29"
                     /gene_synonym="2810405O22Rik; Ixl"
                     /note="hexamer: AATGAA"
     polyA_site      684
                     /gene="Med29"
                     /gene_synonym="2810405O22Rik; Ixl"
                     /note="major polyA site"
     regulatory      1039..1044
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Med29"
                     /gene_synonym="2810405O22Rik; Ixl"
                     /note="hexamer: ATTATA"
     polyA_site      1059
                     /gene="Med29"
                     /gene_synonym="2810405O22Rik; Ixl"
     regulatory      2172..2177
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Med29"
                     /gene_synonym="2810405O22Rik; Ixl"
                     /note="hexamer: AAGAAA"
     polyA_site      2178
                     /gene="Med29"
                     /gene_synonym="2810405O22Rik; Ixl"
ORIGIN      
        1 gcatttatga cgcatttccg gcgttctagc ggaggaaaat ggctgcgccc cagccacagg
       61 ctgcagcggt ttcctctgcg tctggtgtgt caggcccggg ttctgccggg ggtccgggtc
      121 cccagcaaca gccacaaccg acccagttgg tgggttctgc ccagagcggg ctcctgcagc
      181 agcagcagca ggacttcgat cctgtgcagc gctacaagat gctcatcccg caactgaagg
      241 agagtctcca gactttgatg aaggttgcag cccagaatct gattcagaac actaacattg
      301 acaatggaca gaagagcagt gacgcaccct tgcagcgctt tgacaagtgt ttggaggagt
      361 tttacgcact ctgtgatcag ctggaactct gcttgcgcct ggcccacgag tgcctttcac
      421 agagctgtga cagcgccaaa cactctccaa cactggtacc cacagccaca aagccagatg
      481 cagtgcagcc agacagtctg ccctacccac agtacctggc tgtcatcaaa gcccagatca
      541 cctgtgccaa agacattcat actgccctgc tggactgtgc caacaaggtc actggaaaga
      601 ctactgcacc ctctactggc cctgggggca gcctctgagg tctttcgggg aggggcagag
      661 aatgaagtat ggcctgaggc aaaacaggtg gttcctgttg ctgatttgtc cgtgccacag
      721 taatgcagct gaaaccagca gggggcagca gagtcttgca gacagcacag acctcaaacc
      781 ccaccaccac cacaccactg ttgcctccac ccacgctgct ccccaacctg gagtggacct
      841 tcccactggg ccgatgatta cctctgttct ggggactctg actccccacc tggccctggg
      901 ttagcactaa ctgagccctt tagaccttcc tcagtctgtc ccagtgtatg gatttccttt
      961 taacccacct ttttccagtc ctgccatcct atctcaatca gtcccctttt gttgccccca
     1021 acacctaact gggatcgtat tatacaagag gaaccaaaat gcctgggtta ctagggctac
     1081 aggaagggac tttctggctc acaaaagcag cgcgtgaacg taagccctga cctcagcaca
     1141 gacaacctag gagaagtttg ggtccacatt ggaccctgcg tcagcagagc tctctagctg
     1201 ttctggggag gggccgaggg gggatattgt gcaatgtgtg gggaggcctg ctcaacaaga
     1261 ctccttggtc tctatatttt tagctccaaa gcagaagtga aaaggcccca gcttgagtga
     1321 atcatggatt ctggggaaga ccccagctcc tccgggaaac aggccctggg gagggggctt
     1381 tggggaggga ggggaggccc cagcctgtgg gcctggacaa gtgctggatg gaactacaaa
     1441 ccaggcccgg ctgccagtgg aaaggctagc gtgacagact ggttagggaa ctgccccacc
     1501 ccatatcttt tgggccctgg ttcccatgtc accaggttcc tgtgtctaca aaagtcccag
     1561 agactgtgga gacctccatg atgtacagga acccagatca tcacactagg aaaagtggaa
     1621 aatgatcaaa atgagaatgt atacactgtt caggcattcc tccctgccta gcttgactat
     1681 tgcatggtct ttctgcaggg aaggcgagtt ccaccagttt gatcatgggc ctcatttctt
     1741 ttcatttgga gttgtagaga cagtctctca ctccatagcc ggggctagcc ttacagtata
     1801 gtccaggctg ccatggaaca gaacctacct gctattactt gccaagtatt gtgattatat
     1861 cgtgtgagtg tgtggggagt gcttgcttac acgtacaggg tgtatggaag ggggtgcctg
     1921 tgtggagata gagaaagcct tttaggccac agtttctcct gttttcaggc acggaggttc
     1981 tcttgccatc ctgttgcttg gccctttgca cacaccggcc ggcttaggcg ctcccacttt
     2041 gctgtacacg tgttggttgc aggtgtgcac tttagctggt cttcagtgca ctgtggttct
     2101 ttcccctacc ctttaccctc cccgacccag ttttacctcc taatactgga taaacaaggc
     2161 agagaggaat taagaaaa
//
