LOCUS       NM_011869               3388 bp    mRNA    linear   ROD 18-JUN-2024
DEFINITION  Mus musculus mediator complex subunit 24 (Med24), transcript
            variant 3, mRNA.
ACCESSION   NM_011869
VERSION     NM_011869.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3388)
  AUTHORS   Kolonay,D.W., Sattler,K.M., Strawser,C., Rafael-Fortney,J.,
            Mihaylova,M.M., Miller,K.E., Lepper,C. and Baskin,K.K.
  TITLE     Temporal regulation of the Mediator complex during muscle
            proliferation, differentiation, regeneration, aging, and disease
  JOURNAL   Front Cell Dev Biol 12, 1331563 (2024)
   PUBMED   38690566
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3388)
  AUTHORS   Tan,C., Zhu,S., Chen,Z., Liu,C., Li,Y.E., Zhu,M., Zhang,Z.,
            Zhang,Z., Zhang,L., Gu,Y., Liang,Z., Boyer,T.G., Ouyang,K.,
            Evans,S.M. and Fang,X.
  TITLE     Mediator complex proximal Tail subunit MED30 is critical for
            Mediator core stability and cardiomyocyte transcriptional network
  JOURNAL   PLoS Genet 17 (9), e1009785 (2021)
   PUBMED   34506481
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3388)
  AUTHORS   Liu,J., Wang,T., Willson,C.J., Janardhan,K.S., Wu,S.P., Li,J.L. and
            DeMayo,F.J.
  TITLE     ERBB2 Regulates MED24 during Cancer Progression in Mice with Pten
            and Smad4 Deletion in the Pulmonary Epithelium
  JOURNAL   Cells 8 (6), 615 (2019)
   PUBMED   31248101
  REMARK    GeneRIF: MED24 was identified as a crucial oncogenic target of
            ERBB2 in lung tumor development.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3388)
  AUTHORS   Xu,Y., Guo,W., Li,P., Zhang,Y., Zhao,M., Fan,Z., Zhao,Z. and Yan,J.
  TITLE     Long-Range Chromosome Interactions Mediated by Cohesin Shape
            Circadian Gene Expression
  JOURNAL   PLoS Genet 12 (5), e1005992 (2016)
   PUBMED   27135601
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3388)
  AUTHORS   Spies,N., Smith,C.L., Rodriguez,J.M., Baker,J.C., Batzoglou,S. and
            Sidow,A.
  TITLE     Constraint and divergence of global gene expression in the
            mammalian embryo
  JOURNAL   Elife 4, e05538 (2015)
   PUBMED   25871848
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 3388)
  AUTHORS   Ehringer,M.A., Thompson,J., Conroy,O., Xu,Y., Yang,F., Canniff,J.,
            Beeson,M., Gordon,L., Bennett,B., Johnson,T.E. and Sikela,J.M.
  TITLE     High-throughput sequence identification of gene coding variants
            within alcohol-related QTLs
  JOURNAL   Mamm Genome 12 (8), 657-663 (2001)
   PUBMED   11471062
REFERENCE   7  (bases 1 to 3388)
  AUTHORS   Gustafsson,C.M. and Samuelsson,T.
  TITLE     Mediator--a universal complex in transcriptional regulation
  JOURNAL   Mol Microbiol 41 (1), 1-8 (2001)
   PUBMED   11454195
  REMARK    Review article
REFERENCE   8  (bases 1 to 3388)
  AUTHORS   Wertz,K. and Herrmann,B.G.
  TITLE     Large-scale screen for genes involved in gonad development
  JOURNAL   Mech Dev 98 (1-2), 51-70 (2000)
   PUBMED   11044607
REFERENCE   9  (bases 1 to 3388)
  AUTHORS   Zhang,J. and Fondell,J.D.
  TITLE     Identification of mouse TRAP100: a transcriptional coregulatory
            factor for thyroid hormone and vitamin D receptors
  JOURNAL   Mol Endocrinol 13 (7), 1130-1140 (1999)
   PUBMED   10406464
REFERENCE   10 (bases 1 to 3388)
  AUTHORS   Gudkov,A.V., Kazarov,A.R., Thimmapaya,R., Axenovich,S.A., Mazo,I.A.
            and Roninson,I.B.
  TITLE     Cloning mammalian genes by expression selection of genetic
            suppressor elements: association of kinesin with drug resistance
            and cell immortalization
  JOURNAL   Proc Natl Acad Sci U S A 91 (9), 3744-3748 (1994)
   PUBMED   8170981
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL590963.11.
            
            On Mar 13, 2020 this sequence version replaced NM_011869.2.
            
            Summary: This gene encodes a component of the mediator complex
            (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional
            coactivator complex thought to be required for the expression of
            almost all genes. The mediator complex is recruited by
            transcriptional activators or nuclear receptors to induce gene
            expression, possibly by interacting with RNA polymerase II and
            promoting the formation of a transcriptional pre-initiation
            complex. The product of this gene may form a submodule of the
            mediator complex that magnifies the effects of activators on the
            general transcription machinery. Alternatively spliced transcript
            variants of this gene have been described, but their full-length
            nature is not known. [provided by RefSeq, Jul 2008].
            
            Transcript Variant: This variant (3), as well as variants 4 and 6,
            encodes isoform 2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK154618.1, SRR7345562.4270935.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-48                AL590963.11        129158-129205
            49-251              AL590963.11        129590-129792
            252-334             AL590963.11        129880-129962
            335-373             AL590963.11        139721-139759
            374-447             AL590963.11        140007-140080
            448-680             AL590963.11        140435-140667
            681-792             AL590963.11        142052-142163
            793-943             AL590963.11        142296-142446
            944-1057            AL590963.11        142822-142935
            1058-1105           AL590963.11        143449-143496
            1106-1188           AL590963.11        144093-144175
            1189-1275           AL590963.11        144458-144544
            1276-1381           AL590963.11        145318-145423
            1382-1524           AL590963.11        145902-146044
            1525-1562           AL590963.11        147277-147314
            1563-1645           AL590963.11        147722-147804
            1646-1824           AL590963.11        148124-148302
            1825-1924           AL590963.11        148415-148514
            1925-2100           AL590963.11        148820-148995
            2101-2365           AL590963.11        150776-151040
            2366-2547           AL590963.11        151278-151459
            2548-2638           AL590963.11        151661-151751
            2639-2738           AL590963.11        152099-152198
            2739-2819           AL590963.11        152975-153055
            2820-2968           AL590963.11        153310-153458
            2969-3388           AL590963.11        153561-153980
FEATURES             Location/Qualifiers
     source          1..3388
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 62.46 cM"
     gene            1..3388
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /note="mediator complex subunit 24"
                     /db_xref="GeneID:23989"
                     /db_xref="MGI:MGI:1344385"
     exon            1..48
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /inference="alignment:Splign:2.1.0"
     exon            49..251
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /inference="alignment:Splign:2.1.0"
     CDS             122..3085
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /note="isoform 2 is encoded by transcript variant 3;
                     thyroid hormone receptor associated protein 4; mediator of
                     RNA polymerase II transcription subunit 24; mTRAP100;
                     thyroid hormone receptor-associated protein complex 100
                     kDa component; peroxisome proliferation activation
                     receptor binding protein 2; thyroid hormone
                     receptor-associated protein 100 kDa; genetic suppressor
                     element 2"
                     /codon_start=1
                     /product="mediator of RNA polymerase II transcription
                     subunit 24 isoform 2"
                     /protein_id="NP_035999.2"
                     /db_xref="CCDS:CCDS25361.2"
                     /db_xref="GeneID:23989"
                     /db_xref="MGI:MGI:1344385"
                     /translation="MKVVNLKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLAE
                     ALLEQAMIGPSPNPLILSYLKYAISSQMVSCSSVLTAISKFDDFSRDLCVQALLDIMD
                     MFCDRLSCHGKAEECIGLCRALLSALHWLLRCTAASAERLQEGLEAGTPAPGEKQLAL
                     CLQCLEKTLSSTKNRALLHIAKLEEASSWTAIEHSLLKLGEILANLSNPQLRSQAERC
                     GTLIRSIPSMLSVHSEQLHKTGFPTIHALILLEGTMNLTGEMQPLVEQLMMVKRMQHI
                     PTPLFVLEIWKACFVGLIESPEGTQELKWTAFTYLKIPQVLVKLKKYFHGEKDFTEDV
                     NCAFEFLLKLTPLLDKADQRCNCDCTNFLLQECNKQGLLSEVNFASLVGKRTADRDPQ
                     LKSSENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLL
                     AAAAATGKLKSFARKFINLNEFTTHGSGESTKTASVRALLFDISFLMLCHVAQTYGSE
                     VILSESSSGEEVPFFETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMK
                     LVQMKWHEACLSISAAILEILNAWENGVLAFESIQKITDNIKGKVCSLAVCAVAWLVA
                     HVRMLGLDEREKSLQMIRQLAGPLYSENTLQFYNERVVIMNSILEHMCADVLQQTATQ
                     IKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLEKGWVDSRSIHILDTLLHMGGVY
                     WFCNNLIKELLKETRKEHTLRAVQLLYSIFCLDMQQVTLVLLGHILPGLLTDSSKWHS
                     LMDPPGTALAKLAVWCALSSYSSHKGQASSRQKKRHREDIEDYVSLFPVEDMQPSKLM
                     RLLSSSDDDANILSSPTDRSMNSSLSASQLHTVNMRDPLNRVLANLFLLISSILGSRT
                     AGPHTQFVQWFMEECVGCLEQDSRGSILQFMPFTTVSELVKVSAMSSPKVVLAITDLS
                     LPLGRQVAAKAIAAL"
     exon            252..334
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /inference="alignment:Splign:2.1.0"
     exon            335..373
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /inference="alignment:Splign:2.1.0"
     exon            374..447
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /inference="alignment:Splign:2.1.0"
     exon            448..680
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /inference="alignment:Splign:2.1.0"
     exon            681..792
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /inference="alignment:Splign:2.1.0"
     exon            793..943
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /inference="alignment:Splign:2.1.0"
     exon            944..1057
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /inference="alignment:Splign:2.1.0"
     exon            1058..1105
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /inference="alignment:Splign:2.1.0"
     exon            1106..1188
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /inference="alignment:Splign:2.1.0"
     exon            1189..1275
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /inference="alignment:Splign:2.1.0"
     exon            1276..1381
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /inference="alignment:Splign:2.1.0"
     exon            1382..1524
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /inference="alignment:Splign:2.1.0"
     exon            1525..1562
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /inference="alignment:Splign:2.1.0"
     exon            1563..1645
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /inference="alignment:Splign:2.1.0"
     exon            1646..1824
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /inference="alignment:Splign:2.1.0"
     exon            1825..1924
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /inference="alignment:Splign:2.1.0"
     exon            1925..2100
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /inference="alignment:Splign:2.1.0"
     exon            2101..2365
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /inference="alignment:Splign:2.1.0"
     exon            2366..2547
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /inference="alignment:Splign:2.1.0"
     exon            2548..2638
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /inference="alignment:Splign:2.1.0"
     exon            2639..2738
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /inference="alignment:Splign:2.1.0"
     exon            2739..2819
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /inference="alignment:Splign:2.1.0"
     exon            2820..2968
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /inference="alignment:Splign:2.1.0"
     exon            2969..3388
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3367..3372
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /note="hexamer: AATAAA"
     polyA_site      3388
                     /gene="Med24"
                     /gene_synonym="911GSE; D11Ertd307e; DRIP100; Gse2; Pparb2;
                     Pparbp2; Thrap4; Trap100"
                     /note="major polyA site"
ORIGIN      
        1 agtaggtgtc aagatggcgc tgcctacgat gtacaaccgg tttgtatgaa ctccagttct
       61 catctggctc cgtttttaaa ctcccacctt gtcactcatc tcgcctcctt ggagtgacat
      121 catgaaggtg gtgaacctga agcaggccat tttgcaagcc tggaaagagc gatggagtga
      181 ctaccaatgg gcaatcaaca tgaaaaaatt cttccccaaa ggagccacct gggacattct
      241 caacctagca gaagcgctcc tggagcaggc tatgattggg ccttccccca atcctctgat
      301 cctgtcgtac ctgaagtacg ccattagttc ccagatggtg tcctgctcct ctgtgctcac
      361 cgccatcagt aagtttgatg acttttcccg ggacctgtgt gtccaggctc tgctggatat
      421 catggacatg ttctgtgacc gactcagttg ccacggcaaa gcagaggaat gcatcgggtt
      481 gtgccgagcg ctccttagcg ccctccactg gctgcttcga tgtacagcag cttctgcgga
      541 gcgactccag gaagggctgg aggctggcac tccggccccc ggggagaagc agcttgcctt
      601 gtgcttgcag tgcctggaga agaccctcag cagcaccaag aaccgagccc tgctacacat
      661 cgccaaacta gaggaggcct cctcctggac tgccatagag cattctcttc taaaacttgg
      721 ggagatcctg gccaatctca gcaaccccca gctccggagc caagctgagc gttgcggcac
      781 actcatcagg agcatcccca gcatgctgtc cgtgcactcc gagcaactgc acaagaccgg
      841 cttccccacc atccacgcac tcatcttgct tgagggcacc atgaacctga ccggggagat
      901 gcagcccctg gtggagcagc tgatgatggt gaagcgcatg cagcatatcc ccacacctct
      961 ctttgtcctg gaaatctgga aagcttgctt tgtgggactc attgagtccc ccgagggcac
     1021 gcaggagctg aagtggacag ctttcaccta cctcaagatt ccacaggtct tggtgaagtt
     1081 gaagaagtac tttcatggag agaaggattt cacggaggat gtcaactgtg cttttgagtt
     1141 cctgctgaag ctcaccccct tgttggacaa agctgaccag cgctgcaatt gcgactgcac
     1201 gaacttcctc ctccaggagt gcaacaagca ggggcttctg tctgaggtca actttgccag
     1261 ccttgtgggc aaacgcacgg cagatcggga cccgcagcta aaatcatcag aaaatgctaa
     1321 catccagccg aatcctggcc tgatcctgcg ggcagagccc acggtcacaa acattctcaa
     1381 gacaatggat gcagatcact ccaagtcccc ggagggactg ctaggggtcc tgggacatat
     1441 gctgtctggg aagagcctgg atttgctgct ggctgctgcc gccgccactg ggaagcttaa
     1501 atccttcgcc cggaaattca tcaatctgaa tgagttcacg acccacggca gtggagagag
     1561 cacgaaaaca gcctcggtcc gagccttgct ctttgacatt tccttcctca tgctatgcca
     1621 tgtggcccag acctatggct cagaggtgat cctctcggag tcgagctcag gagaagaagt
     1681 ccccttcttt gagacttgga tgcagacctg catgcccgag gagggcaaga ttttgaaccc
     1741 tgaccatccc tgcttccgcc ctgactccac caaagtcgag tccttggtgg ccctgctcaa
     1801 caactcttca gagatgaagc tagtacagat gaagtggcac gaggcctgcc tcagcatttc
     1861 agcagccatt ttggaaatcc tcaacgcttg ggagaatggg gttctggcat ttgagtccat
     1921 ccagaaaatc accgataata tcaagggaaa ggtatgcagt ctggcggtgt gtgctgtggc
     1981 ttggctcgtg gcccacgtcc ggatgctggg gctggatgag cgtgagaagt cactgcagat
     2041 gatccgccag ttggcagggc cactgtacag cgagaacacc ctgcagttct acaatgagag
     2101 ggtggtgatt atgaactcaa tcttggaaca catgtgtgcg gacgtgctcc agcagacagc
     2161 cacgcagatc aagtttccat ccacaggcgt ggacacgatg ccctactgga acctgcttcc
     2221 tcccaagcgc cccatcaagg aggtcctgac agacatcttt gccaaggtac tggagaaggg
     2281 ctgggtggac agccgctcca tccacatcct tgacaccctg ctgcatatgg gcggcgtcta
     2341 ctggttctgc aacaacctga ttaaggagct gctgaaggag actcgcaagg agcacacgtt
     2401 aagggcggtc cagcttctct actccatctt ctgtctggac atgcagcaag tgaccctggt
     2461 cctgctgggt cacatcctgc ccgggctgct tactgactct tccaagtggc acagccttat
     2521 ggaccctcct ggcactgcgc tggccaaact ggctgtgtgg tgtgccctga gctcttactc
     2581 ttcccacaag ggacaggcgt cctcccgcca gaagaagaga cacagagagg acattgagga
     2641 ctatgtcagc ctcttccccg tggaggacat gcagccctcg aagctgatgc gactcctgag
     2701 ctccagtgac gatgatgcca acatcctgtc aagtcccact gaccgctcca tgaacagctc
     2761 cctctcagcc tcccagctcc acacagtcaa catgagggac cctctgaacc gagtcctggc
     2821 caacctgttc ctgctcattt cctccatctt gggttcacgc accgctggcc cccacaccca
     2881 gtttgtgcag tggttcatgg aggagtgtgt gggctgcctg gagcaggaca gcaggggcag
     2941 cattctgcag ttcatgccct tcactaccgt atcagaactg gtgaaagtgt ctgctatgtc
     3001 cagtcccaag gttgttctgg ccatcacaga cctcagcctg cccctgggcc ggcaggtggc
     3061 cgccaaagcc attgctgcac tctgaggagc tccgtgtggc ctgcagtggg tcccagcccc
     3121 atcatccaag cagggagcca ggagagtgag accttcccac ccctgccctg actcatcatg
     3181 gccctacaca tctcccagtg gcttttgtaa tttctgtcct ttgaaccagc acccaaagac
     3241 tctgagcagt ccctatggtc accccaagta gctgtacctc caggagggac tttatagggc
     3301 cacagtgtgt atataagttt tatttttata acccatgaat ggggagtccc ccttggttcc
     3361 tctgtaaata aagatccttg tggctgtg
//
