LOCUS       XM_036162892            5516 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus MDS1 and EVI1 complex locus (Mecom),
            transcript variant X12, mRNA.
ACCESSION   XM_036162892
VERSION     XM_036162892.1
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000069.7) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Mar 12, 2024 this sequence was replaced by
            NM_001428448.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5516
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="3"
     gene            1..5516
                     /gene="Mecom"
                     /gene_synonym="D630039M04Rik; Evi-1; Evi1; Jbo; Mds; Mds1;
                     Mds1-Evi1; Prdm3; Znfpr1b1"
                     /note="MDS1 and EVI1 complex locus; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 17
                     ESTs, 39 long SRA reads, and 99% coverage of the annotated
                     genomic feature by RNAseq alignments, including 25 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:14013"
                     /db_xref="MGI:MGI:95457"
     CDS             1152..3974
                     /gene="Mecom"
                     /gene_synonym="D630039M04Rik; Evi-1; Evi1; Jbo; Mds; Mds1;
                     Mds1-Evi1; Prdm3; Znfpr1b1"
                     /codon_start=1
                     /product="histone-lysine N-methyltransferase MECOM isoform
                     X11"
                     /protein_id="XP_036018785.1"
                     /db_xref="GeneID:14013"
                     /db_xref="MGI:MGI:95457"
                     /translation="MKSEEDPHEPMAPDIHEERQHRCEDCDQLFESKAELADHQKFPC
                     STPHSAFSMVEEDLQQNLESESDLREIHGNQDCKECDRVFPDLQSLEKHMLSHTEERE
                     YKCDQCPKAFNWKSNLIRHQMSHDSGKHYECENCAKVFTDPSNLQRHIRSQHVGARAH
                     ACPECGKTFATSSGLKQHKHIHSSVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIK
                     CKDCGQMFSTTSSLNKHRRFCEGKNHFAAGGFFGQGISLPGTPAMDKTSMVNMSHANP
                     GLADYFGTNRHPAGLTFPTAPGFSFSFPGLFPSGLYHRPPLIPASPPVKGLSSTEQSN
                     KCQSPLLTHPQILPATQDILKALSKHPPVGDNKPVELLPERSSEERPLEKISDQSESS
                     DLDDVSTPSGSDLETTSGSDLESDLESDKEKCKENGKMFKDKVSPLQNLASITNKKEH
                     NNHSVFSASVEEQSAVSGAVNDSIKAIASIAEKYFGSTGLVGLQDKKVGALPYPSMFP
                     LPFFPAFSQSMYPFPDRDLRSLPLKMEPQSPSEVKKLQKGSSESPFDLTTKRKDEKPL
                     TSGPSKPSGTPATSQDQPLDLSMGSRGRASGTKLTEPRKNHVFGEKKGSNMDTRPSSD
                     GSLQHARPTPFFMDPIYRVEKRKLTDPLEALKEKYLRPSPGFLFHPQMSAIENMAEKL
                     ESFSALKPEASELLQSVPSMFSFRAPPNTLPENLLRKGKERYTCRYCGKIFPRSANLT
                     RHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCDRCFGQQTNLDR
                     HLKKHENGNMSGTATSSPHSELESAGAILDDKEDAYFTEIRNFIGNSNHGSQSPRNME
                     ERMNGSHFKDKKALATSQNSDLLDDEEVEDEVLLDEEDEDNDIPGKPRKELGVTRLDE
                     EIPEDDYEEAGALEMSCKASPVRHML"
ORIGIN      
        1 cacacacaca cacacacaca cccttgtgct caggacatca aaaccaaaga gatttccctg
       61 gggaaacaaa tcctgcctgg agaaatttcc ccattggttg tttatcggca gaaatctaca
      121 tgtttctggg gatggtgcat ctataatcag tctgtcccta taggacttgg gtcttggcga
      181 cctttttgtg acctctcccg ccagaggagg ctgctgtcac tttaaaaatt tactgaaaga
      241 ggagcccgtc gtctggcttc cgaccactct ggagatagct ccctttctcc ctcgccccgg
      301 tttctttctg gatggccgag cagatcccct ttaaagagac agttcatgaa atagaaaccc
      361 tgcggctggg cgcggagtgg ctaaagggga cgagccggtg agggtctggc cccgagaagg
      421 ctctgggagg acctgggggg ccgtcctggc ctggcaggcc ccctaccttc gcacactttc
      481 ctcctgcggg tcttgcccct ggagctgcga cagaggagtg ggagaagttt tagtaggttt
      541 cagataactt tcattacaca tcgggctgat aagagcaaga gaaagtgagg aaagagggag
      601 gtagtgagac cagaaggaat agctgcgagc tcatttagga agaggggaaa aacccaaata
      661 caccaaaccc ggctcaattc tggtcttaaa acactgttgg cggacaataa atccgaaacg
      721 cgtggtcctg gcgatcagct cccagggaac gacaaactta tcagacaccc atttggaagt
      781 ggagacacga ggcttttatt ttaaaaaaaa attttttttt cttttaaaat atctcgaaat
      841 gttagcgggt gttctttgaa aagattttcc aactcgagta cctggctgct gctgatctta
      901 tttttgttta attctgctgt gattgctttt gattgctgag ttgaggccgt agaaatcgga
      961 agatcttaga tgagttttgc aatgtgaagt tctgcataga tgccagtcaa ccagatgtag
     1021 gaagctggct caagtacatc agattcgctg gctgctatga tcagcacaac cttgttgcat
     1081 gccagataaa tgatcagata ttctaccgag tagtcgcaga cattgcgcct ggggaagagc
     1141 tcttgctgtt catgaagagt gaagaggacc cgcacgaacc catggcgcct gacatccacg
     1201 aagaacggca gcaccgctgt gaggactgtg accagctctt tgaatccaag gcagagctag
     1261 ccgatcacca gaagttccca tgcagcacac ctcactcggc cttctccatg gtggaggagg
     1321 acttgcaaca aaacctggag agtgagagcg atctccgaga gatccatggc aaccaggact
     1381 gtaaggaatg tgaccgagtt ttccccgatc tgcaaagctt ggagaagcac atgctgtcac
     1441 atactgagga gagggaatac aagtgtgatc agtgtcccaa ggcatttaac tggaagtcca
     1501 atttaattcg ccaccagatg tcacatgaca gtggaaagca ctatgagtgt gaaaactgtg
     1561 ccaaggtttt cacggaccct agcaaccttc agcgacacat tcgatctcag catgttggtg
     1621 cccgggctca tgcttgcccc gagtgtggta aaacatttgc cacttcgtca ggcctcaaac
     1681 agcacaagca catccacagc agtgtgaagc cctttatctg tgaggtctgc cataaatcct
     1741 atactcagtt ttcaaacctt tgtcgtcata agcgcatgca tgctgattgc agaacccaaa
     1801 tcaagtgcaa agactgtgga caaatgttca gcactacgtc ttccttaaat aaacacagga
     1861 ggttttgtga gggcaagaac cattttgcgg caggtggatt ttttggccaa ggcatttcac
     1921 ttcctggaac cccagctatg gataaaacgt ccatggttaa tatgagtcat gccaacccgg
     1981 gcctggctga ctattttggc accaataggc atcctgctgg tcttaccttt ccaacagctc
     2041 ctggattttc ctttagcttt cctggtctgt ttccttcggg cttataccac aggcctcctt
     2101 tgatacccgc tagtcctcct gttaaaggat tatcaagtac cgaacagtca aacaaatgtc
     2161 aaagtcccct cttgacacat cctcagatac tgccagctac acaggatatt ttgaaggcac
     2221 tatctaaaca cccacctgta ggggacaata agccagtgga actgctgccc gagaggtcct
     2281 ctgaagagag gccccttgag aaaatcagtg accagtcaga gagtagtgac cttgatgatg
     2341 tcagtacacc aagtggcagt gacctggaaa caacctcggg ctctgatctg gaaagtgacc
     2401 ttgaaagtga taaagagaaa tgtaaagaaa atggtaaaat gttcaaagac aaagtaagcc
     2461 ctctgcagaa tctggcttcg ataactaata agaaagaaca caacaatcat tccgttttct
     2521 cagcatctgt agaggagcaa agtgccgtgt caggagctgt gaatgattct ataaaggcta
     2581 ttgcgtctat tgctgaaaaa tactttggtt ctacaggact ggtggggctg caagacaaaa
     2641 aagttggagc gttaccttac ccttccatgt ttcccctccc gttttttcca gcattctctc
     2701 aatcaatgta cccatttcct gatagagact tgaggtcgtt acctttgaaa atggagcccc
     2761 aatcaccaag tgaagttaag aaactgcaga agggaagctc tgagtcccct tttgacctca
     2821 ccactaagag aaaggatgag aagcccttga cttcaggccc ctcgaagcct tcaggaacac
     2881 cagccacaag ccaagaccag cccctggatc taagtatggg cagtaggggt agagccagtg
     2941 ggacaaagtt gactgagcct cgaaaaaacc atgtgtttgg ggaaaagaaa ggaagcaaca
     3001 tggatactag gccatcttca gatggctcct tgcagcatgc cagacccact cccttcttca
     3061 tggaccccat ttatagagta gagaaaagaa agttaactga cccgcttgaa gctttgaaag
     3121 aaaaatactt gagaccttct ccaggattct tgtttcaccc gcaaatgtca gcaattgaga
     3181 acatggcaga aaagctggaa agcttcagcg ccctcaaacc tgaggccagc gagctcctgc
     3241 agtccgtgcc ctccatgttc agcttccgag ctcctcccaa caccctgcca gagaacctgc
     3301 tgcggaaggg gaaagagcgc tacacctgca ggtactgtgg caagatattt ccaaggtctg
     3361 cgaacctaac acggcacttg agaacccaca caggagagca accttacaga tgcaaatact
     3421 gtgatagatc attcagcatt tcttccaacc tgcagcgaca tgtgcgcaac atccacaaca
     3481 aggagaagcc atttaagtgt catttatgtg acagatgttt tggtcaacaa accaatcttg
     3541 acagacacct gaagaaacat gagaacggca acatgtctgg gacggcaacg tcctcgcctc
     3601 actcagagct agaaagcgca ggcgcaatcc tggatgacaa agaagatgcg tactttacag
     3661 agatccgcaa tttcatcggg aacagcaacc atggtagcca gtctcctcgg aacatggaag
     3721 agaggatgaa tggcagtcac ttcaaggata aaaaggcttt ggcaaccagc caaaattcag
     3781 atttattgga tgatgaagaa gtagaagatg aggtgttgtt ggatgaggag gatgaagaca
     3841 atgatattcc tggaaagccc agaaaggagc taggggtgac tcgtttagac gaggagatcc
     3901 cggaggatga ctacgaagaa gctggtgccc tggagatgag ctgtaaggcg tccccggtga
     3961 ggcatatgct atgatgttgt cactgtctga caaggattcc ctccatccca cctcccacag
     4021 ttcctccaac gtgtggcaca gcatggcaag ggctgcagca gaatccagtg ccatccagtc
     4081 cataagccat gtatgacatt gtcaaggttg accagagtgg gaccaagtcc aacggtagca
     4141 tggctctttc atacagaaca atttacaaga ctgctgagca ggatgcctta taaccctgaa
     4201 gggtcacgca tttaaagtct ggtgacctta aactgaatga gtaaagaaag agagagaaaa
     4261 aggaagctat ttattctcaa tattttgttt tgcacagcca aggcagctgc tgacttctgg
     4321 aggatcaatt aatccaaaat gattggaggg gaaaggaaac ctcaccaggg aaggcatctt
     4381 tcattccccc tgccgcaggg catgggtggc tgagaggagc agttgaaatg gcagcattga
     4441 tataaatgga catttcatag aaatcaaact ctactctaca ggatcacctg atctgactgg
     4501 gaacagtggc ttctaactac cagatttttt ttttcctttt taaagtttta tgtaatttaa
     4561 tcttttgcag atggaagtag tcagaagaaa tgcacaatga ttataggaag tgatagcagg
     4621 attttttgtc accccccaca ccctcttaac tttggccttc ttgagtacat tgtttaaaac
     4681 tagggggaaa aaagggtatg tgtatattgt aaactatgga tgctcatgca gagaggttaa
     4741 gtcggtgaca taactgttta tcaccactgt accactaata caatgtttgc caaatccttg
     4801 taatgacatc ttaattttag acaatcatgt cactgttttt aatgtttcaa tttttttgtg
     4861 tgttgtgtgt atcatgtatt tatttgttgg caaactatgg tttgttgatc aaaaagagca
     4921 ctgttcccgt cagccactat tttatgatgt ctgaggcaca cccctttctg aattccaagg
     4981 accaaggtga catgacctgt gtatgggagt gcccaatagt gtttggcttt tcttaacatt
     5041 ccttcctttt tgttgttgtt gttttgtttt cctttttaat gaactaaata ccaatagatg
     5101 caacttagtt tttgtaatac tgaaatcgat tcaattgtat aaatgattat aatttctttc
     5161 atggaagcat gatccttctg attaagaact gtaccccata ttttatgctg gttgtctgca
     5221 agcttgtgcg atgatgttat gttcatgtta atcctatttg taaaatgaag tgttcctgac
     5281 cttatgttaa aaagagagaa gtaaataaca gacattattc agttattttg tcctttatcg
     5341 aaaaaccaga tttcattttt cctttttgtt tgtgatctca tttggaaata attggcaagt
     5401 tgaggtactt tcttcccatg ctttgtacaa tataaactgt tatgcctttc agtgcgttac
     5461 tgtgggagga gcaactaaaa aaaaaaataa agacttccaa aaatcatgaa aaataa
//
