LOCUS       NM_001374123            4553 bp    mRNA    linear   ROD 09-JUN-2024
DEFINITION  Mus musculus MYST/Esa1-associated factor 6 (Meaf6), transcript
            variant 4, mRNA.
ACCESSION   NM_001374123 XM_006503382
VERSION     NM_001374123.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4553)
  AUTHORS   Matsuura,K., Tani,N., Usuki,S., Torikai-Nishikawa,S., Okano,M. and
            Niwa,H.
  TITLE     MEAF6 is essential for cell proliferation and plays a role in the
            assembly of KAT7 complexes
  JOURNAL   Exp Cell Res 396 (1), 112279 (2020)
   PUBMED   32918898
  REMARK    GeneRIF: MEAF6 is essential for cell proliferation and plays a role
            in the assembly of KAT7 complexes.
REFERENCE   2  (bases 1 to 4553)
  AUTHORS   Jacquet,K., Fradet-Turcotte,A., Avvakumov,N., Lambert,J.P.,
            Roques,C., Pandita,R.K., Paquet,E., Herst,P., Gingras,A.C.,
            Pandita,T.K., Legube,G., Doyon,Y., Durocher,D. and Cote,J.
  TITLE     The TIP60 Complex Regulates Bivalent Chromatin Recognition by 53BP1
            through Direct H4K20me Binding and H2AK15 Acetylation
  JOURNAL   Mol Cell 62 (3), 409-421 (2016)
   PUBMED   27153538
REFERENCE   3  (bases 1 to 4553)
  AUTHORS   Doyon,Y., Cayrou,C., Ullah,M., Landry,A.J., Cote,V., Selleck,W.,
            Lane,W.S., Tan,S., Yang,X.J. and Cote,J.
  TITLE     ING tumor suppressor proteins are critical regulators of chromatin
            acetylation required for genome expression and perpetuation
  JOURNAL   Mol Cell 21 (1), 51-64 (2006)
   PUBMED   16387653
REFERENCE   4  (bases 1 to 4553)
  AUTHORS   Taniwaki,T., Haruna,K., Nakamura,H., Sekimoto,T., Oike,Y.,
            Imaizumi,T., Saito,F., Muta,M., Soejima,Y., Utoh,A., Nakagata,N.,
            Araki,M., Yamamura,K. and Araki,K.
  TITLE     Characterization of an exchangeable gene trap using pU-17 carrying
            a stop codon-beta geo cassette
  JOURNAL   Dev Growth Differ 47 (3), 163-172 (2005)
   PUBMED   15840001
REFERENCE   5  (bases 1 to 4553)
  AUTHORS   Doyon,Y., Selleck,W., Lane,W.S., Tan,S. and Cote,J.
  TITLE     Structural and functional conservation of the NuA4 histone
            acetyltransferase complex from yeast to humans
  JOURNAL   Mol Cell Biol 24 (5), 1884-1896 (2004)
   PUBMED   14966270
REFERENCE   6  (bases 1 to 4553)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   7  (bases 1 to 4553)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK012867.1, BQ178199.1, CO428776.1 and AL626775.11.
            
            On Sep 11, 2019 this sequence version replaced XM_006503382.4.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219383.120702.1,
                                           SRR9219381.164035.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849389, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-19                AK012867.1         2-20
            20-722              BQ178199.1         1-703
            723-778             CO428776.1         526-581
            779-1384            AK012867.1         748-1353
            1385-4553           AL626775.11        154425-157593
FEATURES             Location/Qualifiers
     source          1..4553
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 58.03 cM"
     gene            1..4553
                     /gene="Meaf6"
                     /gene_synonym="2310005N01Rik; 2810036M01Rik"
                     /note="MYST/Esa1-associated factor 6"
                     /db_xref="GeneID:70088"
                     /db_xref="MGI:MGI:1917338"
     exon            1..106
                     /gene="Meaf6"
                     /gene_synonym="2310005N01Rik; 2810036M01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            107..222
                     /gene="Meaf6"
                     /gene_synonym="2310005N01Rik; 2810036M01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            223..310
                     /gene="Meaf6"
                     /gene_synonym="2310005N01Rik; 2810036M01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            311..356
                     /gene="Meaf6"
                     /gene_synonym="2310005N01Rik; 2810036M01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            357..549
                     /gene="Meaf6"
                     /gene_synonym="2310005N01Rik; 2810036M01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            550..579
                     /gene="Meaf6"
                     /gene_synonym="2310005N01Rik; 2810036M01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            580..613
                     /gene="Meaf6"
                     /gene_synonym="2310005N01Rik; 2810036M01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            614..4553
                     /gene="Meaf6"
                     /gene_synonym="2310005N01Rik; 2810036M01Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1184..1189
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Meaf6"
                     /gene_synonym="2310005N01Rik; 2810036M01Rik"
                     /note="hexamer: ACTAAA"
     polyA_site      1207
                     /gene="Meaf6"
                     /gene_synonym="2310005N01Rik; 2810036M01Rik"
                     /note="major polyA site"
     regulatory      1363..1368
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Meaf6"
                     /gene_synonym="2310005N01Rik; 2810036M01Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1384
                     /gene="Meaf6"
                     /gene_synonym="2310005N01Rik; 2810036M01Rik"
     regulatory      4530..4535
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Meaf6"
                     /gene_synonym="2310005N01Rik; 2810036M01Rik"
                     /note="hexamer: AATAAA"
     polyA_site      4553
                     /gene="Meaf6"
                     /gene_synonym="2310005N01Rik; 2810036M01Rik"
ORIGIN      
        1 gccgcttgag cccaacatgg cgatgcacaa caagacggcg ccgccgcaga tcccagacac
       61 ccggcgggag ctggccgagc tggttaagcg gaagcaggag ctggcggaaa cacttgcaaa
      121 cttggagaga cagatatatg cttttgaagg aagctacctg gaagacactc agatgtatgg
      181 caatattatc cgtggctggg atcggtattt gaccaatcaa aagaactcca atagcaaaaa
      241 cgaccggagg aaccggaagt tcaaggaggc cgaacggctc ttcagcaaat cctcagtcac
      301 gtcggctgct gcagtaagtg ccttggcagg ggttcaggac cagctcatcg aaaagaggga
      361 accaggaagt gggacggaaa gcgatacttc tccagacttc cacaatcagg aaaacgagcc
      421 tgcgcaggag gaccccgagg acctagacgg ctccgtccag ggagtgaaac ctcagaaagc
      481 cgcctcttcc acctcctcag gaagccacca cagcagccac aaaaaacgga agaataaaaa
      541 ccggcacagc ccgtctggca tgtttgatta tgactttgag attgatctga agttaaacaa
      601 aaagccccga gctgactatt agaagacttg ctggcagaag cttccaggct gtgaagcttc
      661 ccctctgacc tcacagccac aaatgtccct tgcctgactg tggccatctg cctctgcccc
      721 ccagacccag tgcctgtgac tggctagtct gacctaactg tagtgacaag tcctccctat
      781 aagacttttt gggtcattcg ctgctgtcgt catcattagt agaacagcgg gaagacctgt
      841 cctccgtccc agtccctgcg ggtggctaac tgtgcatttc tcccttctta gaatgaatgt
      901 ctccccccaa actggctggc accagctcca tctgtgacac ccccgccccc atcgagaagt
      961 gcacacacct ctgattctgt gttaagctga aagtagaacc caaggtccat tgcagatgga
     1021 ggctgtaaat atctgccatt ctcttgtttt gttttgtgtt gtattgtttt tttattgttg
     1081 cttttaccat ctgattttct tttgggacat tttgtgatgc ctgtaccttc ctgatgacac
     1141 atctgatcgt ctgtttcatg tggtgtcgat attcataact gaaactaaag tggcttttag
     1201 aaggaaatgg gcagctgcct ctttggcttc ttgatttctt cagggggaag ggagagagtg
     1261 ttttcacggt ggatggccta tcaggaacag ttttatgtgg gaggaacaag aagctaaaca
     1321 gcacacgttg aaaccctccc attggagtag actctttgta ggaataaaat ctccctggct
     1381 cgcccttctc atgtgctcct tctaaaccca aacccgagac gctttcctct tcattttact
     1441 actatcatgc ctgtgggaga atttcttttt ccatcttttc tcgttttgct gacatccacc
     1501 tgcttagata ctgctctaaa aatcgccaag ccagtggaaa agcctagaat tactgaacct
     1561 cagttcccac cgagtagagt gagatcctca caggagcctg gcctgcctac agacatcccc
     1621 ttccctgtag agctcactcc atgcccgtcc tcgtgtcctt ggctgtcctc agtgagtggc
     1681 cgtggatggc cactttgcag tcacctgggc agctcagccc agtgtggatg ctagtatccc
     1741 aaccctggaa ccctcgggta tgcctcggtg ttgggcttgg aacacagagt ccaggctgtt
     1801 gattgggagc ctgctggagg ccactgtgtt aagagactga gcatatagca ctggatcagg
     1861 ctgaggggta agattcaggg ccttgcctgt cctctctgac gcctgggtct ttgtaggaga
     1921 cttgggccgt tgtggtccat gctgttggcg gagatggctg gcctcttcac cagaaccacc
     1981 ctgtcagatg tgcaaaagcc tttcattttg ttcttaaaca gactcccatt ttcttggatg
     2041 gtttcctgat ctttggcttt ggctttcttc tgaaggaagt agtttataat atgtagattg
     2101 ttccttgaga aggaaaatct cagaagcatt ctgttagttt tattgcttca tccttaacgc
     2161 tgaggaaagt gtgcgactca aaaacatctg gacctccaca gttggctgtg ccctggagga
     2221 ccggtggaac tgctcagtag aaggtgtgtt atttatttat ggcagggtag agagttagat
     2281 acagagcccc acatgctagg caagtgacct accactgagt tccctcccag tccctaaagg
     2341 tgtgttatgc agtagcatgt ctgtgtgtgt gactgaccct gtgtgtgtgt tgaagactgg
     2401 cttgtgggct gtttgtttta tgccttcccc atccccagtc cccaccctgt agagtttggc
     2461 cattgattgg gtcttctagt tttcccgtaa actggacatc agtactcagg ctttgataaa
     2521 ttacttgctt tccctatttc tgggtagcat cgaataaggg catcaagaag acgagtggca
     2581 tagctcagtg acggagtaat tgtctagcat gcagggggtc gaccctcagt gccatgtcaa
     2641 cctggctgtg gtgacggatg catgccttta atcctagccc tcggaaggaa ggattcgaag
     2701 tcaaggatca tccctggcta cgcagggagt tggaggtcag tttgggccac aaaggaattt
     2761 tattttaaaa acaaaatacc aactccaata aatgctgaca ctgactttat caaccaagtt
     2821 ggcttacaac tcatcgaagg aaggagtgag tgtgcttgct tacacagagg aactttattc
     2881 ttagtggaca agattgcctt tcggtgcagc cagccagcag tccctacacg gaagtgccat
     2941 ctgtggctct gtgtgttgtg ggagggactg gtttaaggag agttagccaa ctcctgagtc
     3001 aggagtggca gcacacgcca atgaccttag cacttgggaa gtggaagcag aggagttcga
     3061 ggccagccta ggctgttatt acctggcctg tgttggagcg gggtgagaag caacagctga
     3121 ttccagtgac cctcctgtcc ctcggaagga caaaggaaag gcacgtgggg gtggggacgg
     3181 acagcacatt agctgctgcc atttgttgct ccgtgcctct ctctaactag ggaagcgctc
     3241 gcccttggcc gctggtaggt gtaagacaag acacagcctt ttgtggtaac ttctgtgtcc
     3301 actacttgga ggccactcta gtgcagcgct tcatgggact atcaagtgta ctattccaag
     3361 gactgaggaa ggggtcactc tgtttacagt cagtgtccca gcactgctgg tgcaggagga
     3421 ggtggggagc gggaccggcc cacagagttg gagtctgcac tgggacaagg ctagtgtggg
     3481 gccaagaact acacttttcg aagctgctgt tctgacccag tgaggcccca ggtctccgga
     3541 gccttggggc cccgggagaa agggttctac ggccgcacag gttaaaccat ttctccacac
     3601 ttgagtttgt aatgtttgct ttcaggaaac acttttgttc tgagagtagg aagcaggcag
     3661 tggggtcttc acctgaaaac gtgagctttt gttcctgggc tctgcaagtg tagagagtgg
     3721 tggtcctagt cttcaccctg gaagtataaa ggaaacaaac gctaaggagc ctgcacttgt
     3781 aagccggtgg tgtgtggctc tgaagggctc tccagtttgg cttgtgcacc tatttgggct
     3841 ttgccacctc tgcctgattc caaatcacta aggcatttgc acactcgcag atctattcag
     3901 gctgatgttc tggtagaagg aaggcagtct gaatagtgcc taggaaaact gtgtgtgtgt
     3961 atgtgtctgt acctaggaag gctctgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg
     4021 tgtgtgtgtg tgtttgtgtt tgtgtatcta ggaaggctgt gtgtgtttgt gtatctagga
     4081 aggctgtgtg tgtttatgca ttcatgtgtg tgtgtgtgtt tgtgtacctg ggaaggctct
     4141 gtgtgggtgt gtgggtgtgt gtatacgcac acacgccctt gcatggaaga gtgtgagggg
     4201 agggtacagc agtgtagtgc aggatatgct ggtctaaccc agtgttcaaa gtgggtgatc
     4261 caggtctgga tctgcctggt cagcttcagg atttgaagca caggttcatt ctgagcactg
     4321 ttctatggag tcagtcgtac tgtgggtctg aaaggaagca gggtgcgatg gtgggggtgt
     4381 ccgagggaaa gggctgggga tgtggaagga aaagagcaga tcttggatgt gtttccactt
     4441 tgggcctcaa ccctatgtag ttcctcactt tggatatgtt gtgtaataca cataactatt
     4501 agttcattaa tacatgtgga taatttataa ataaatatta ggttgaacca caa
//
