LOCUS       NM_001413530             991 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus male enhanced antigen 1 (Mea1), transcript variant 7,
            mRNA.
ACCESSION   NM_001413530 XM_006523749
VERSION     NM_001413530.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 991)
  AUTHORS   Hwang,I., Kim,B.S., Ko,H.R., Cho,S., Lee,H.Y., Cho,S.W., Ryu,D.,
            Shim,S. and Ahn,J.Y.
  TITLE     Cerebellar dysfunction and schizophrenia-like behavior in
            Ebp1-deficient mice
  JOURNAL   Mol Psychiatry 27 (4), 2030-2041 (2022)
   PUBMED   35165395
REFERENCE   2  (bases 1 to 991)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   3  (bases 1 to 991)
  AUTHORS   Ortega-Lazaro,J.C. and del Mazo,J.
  TITLE     Expression of the B56delta subunit of protein phosphatase 2A and
            Mea1 in mouse spermatogenesis. Identification of a new B56gamma
            subunit (B56gamma4) specifically expressed in testis
  JOURNAL   Cytogenet Genome Res 103 (3-4), 345-351 (2003)
   PUBMED   15051958
  REMARK    GeneRIF: A comparative expression study of Mea1 and the B56delta
            subunit of protein phosphatase 2A in spermatogenesis.
REFERENCE   4  (bases 1 to 991)
  AUTHORS   Ohinata,Y., Sutou,S., Kondo,M., Takahashi,T. and Mitsui,Y.
  TITLE     Male-enhanced antigen-1 gene flanked by two overlapping genes is
            expressed in late spermatogenesis
  JOURNAL   Biol Reprod 67 (6), 1824-1831 (2002)
   PUBMED   12444059
  REMARK    GeneRIF: localization of the male-enhanced antigen-1 suggests that
            it may function in the very late stages of spermiogenesis
REFERENCE   5  (bases 1 to 991)
  AUTHORS   Kondo,M., Sato,S. and Sutou,S.
  TITLE     Cloning and sequence analysis of cDNA encoding the bovine
            testis-derived male-enhanced antigen (Mea)
  JOURNAL   Biochim Biophys Acta 1216 (3), 483-486 (1993)
   PUBMED   8268232
REFERENCE   6  (bases 1 to 991)
  AUTHORS   Himmelbauer,H. and Silver,L.M.
  TITLE     High-resolution comparative mapping of mouse chromosome 17
  JOURNAL   Genomics 17 (1), 110-120 (1993)
   PUBMED   8406442
REFERENCE   7  (bases 1 to 991)
  AUTHORS   Lau,Y.F., Chan,K.M. and Sparkes,R.
  TITLE     Male-enhanced antigen gene is phylogenetically conserved and
            expressed at late stages of spermatogenesis
  JOURNAL   Proc Natl Acad Sci U S A 86 (21), 8462-8466 (1989)
   PUBMED   2813404
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CT030702.11.
            
            On Nov 3, 2022 this sequence version replaced XM_006523749.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7652917.765089.1,
                                           SRR7345562.565034.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-216               CT030702.11        188541-188756       c
            217-497             CT030702.11        187966-188246       c
            498-600             CT030702.11        187752-187854       c
            601-991             CT030702.11        186754-187144       c
FEATURES             Location/Qualifiers
     source          1..991
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 22.9 cM"
     gene            1..991
                     /gene="Mea1"
                     /gene_synonym="Mea-1"
                     /note="male enhanced antigen 1"
                     /db_xref="GeneID:17256"
                     /db_xref="MGI:MGI:96957"
     exon            1..216
                     /gene="Mea1"
                     /gene_synonym="Mea-1"
                     /inference="alignment:Splign:2.1.0"
     exon            217..497
                     /gene="Mea1"
                     /gene_synonym="Mea-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             228..752
                     /gene="Mea1"
                     /gene_synonym="Mea-1"
                     /note="isoform b is encoded by transcript variant 7"
                     /codon_start=1
                     /product="male-enhanced antigen 1 isoform b"
                     /protein_id="NP_001400459.1"
                     /db_xref="GeneID:17256"
                     /db_xref="MGI:MGI:96957"
                     /translation="MAAVVLGGDTMGPERIFPNQTEDLGPHQGPTEGTGDWSSEEPEE
                     EQEETGAGPAGYSYQPLNQDPEQEEVELAPVGEGEDGAADIQDRIQALGLHLPDPPLE
                     SEDEDEEGAAALSSHSSIPMDPEHVELVKRTMAGVSLPAPGVPAWAREISDAQWEDVV
                     QKALQARQASPAWK"
     exon            498..600
                     /gene="Mea1"
                     /gene_synonym="Mea-1"
                     /inference="alignment:Splign:2.1.0"
     exon            601..991
                     /gene="Mea1"
                     /gene_synonym="Mea-1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      959..964
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mea1"
                     /gene_synonym="Mea-1"
                     /note="hexamer: AATAAA"
     polyA_site      991
                     /gene="Mea1"
                     /gene_synonym="Mea-1"
                     /note="major polyA site"
ORIGIN      
        1 gcatgtcctg ccccgccgga agtgaaggtg cgggtccggc tgtgggctct gagagggtga
       61 ggcgcgagga aataccaacg ccgagaatca gtggggcggg taggggactc tgtagctggg
      121 gccattgaag gggagaccct gggcctgaag gggtttttgc caggcggtac tacactcccc
      181 cggaatagag ggaatgaggg gcggggacgc gctatgcccc tgcccggatg gcagcagtag
      241 ttctaggggg agacaccatg ggccctgagc gtatcttccc caatcagact gaggacttag
      301 ggccacatca gggtcctaca gaaggaactg gggattggag cagtgaagaa cccgaggaag
      361 agcaggagga aacaggagca ggcccagcag gctactcgta ccagcccctc aatcaagacc
      421 ctgaacaaga agaggtggaa ttggcaccag tgggtgaagg agaagatgga gctgctgaca
      481 tccaagatcg gatccaggcc ctggggcttc atctgccaga ccctccattg gagagtgagg
      541 atgaagatga ggagggagcc gccgcattga gcagccacag ctctatcccc atggacccag
      601 aacatgtaga gctggtgaaa aggacgatgg ctggagtaag cctgcctgca ccaggggttc
      661 ctgcctgggc tcgggagatc tcggacgctc agtgggaaga tgtggtacag aaagccctcc
      721 aagcccggca ggcatcccct gcctggaagt gaccagagag cgagctgcct tacctcccta
      781 cattccaagt caggaccagc acaggactaa caactctggt cttaacagcc tcctccttcc
      841 catgtccctt tcacaccaag gcgactcaga cctctcagag acccacttta ttcagttctg
      901 tacatatggg gacatcggcc caagcccagc ccaccttagc atgtatcact ctgtggagaa
      961 taaagcaccc tgtgtacaca gccagaagcc a
//
