LOCUS       XM_006508790            8713 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus microcephaly, primary autosomal recessive 1
            (Mcph1), transcript variant X15, mRNA.
ACCESSION   XM_006508790
VERSION     XM_006508790.3
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000074.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Aug 8, 2019 this sequence version replaced XM_006508790.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8713
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="8"
     gene            1..8713
                     /gene="Mcph1"
                     /gene_synonym="5430437K10Rik; BRIT1; D030046N04Rik; MCT;
                     Tg(HLA-A2.1)1Enge"
                     /note="microcephaly, primary autosomal recessive 1;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 1 mRNA, 7 ESTs, 241 long SRA reads, and 95%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 6 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:244329"
                     /db_xref="MGI:MGI:2443308"
     CDS             97..2085
                     /gene="Mcph1"
                     /gene_synonym="5430437K10Rik; BRIT1; D030046N04Rik; MCT;
                     Tg(HLA-A2.1)1Enge"
                     /codon_start=1
                     /product="microcephalin isoform X15"
                     /protein_id="XP_006508853.1"
                     /db_xref="GeneID:244329"
                     /db_xref="MGI:MGI:2443308"
                     /translation="MLEQSQQNPCVSLFETSLNISHQPLSSDESFASGSHSSFGDSCG
                     DQERKLGRSANEMTTVTCPSSPVLRASSFYGSASPNHLRQPRPQKAPDSPSKESINCQ
                     KDATGAVADSERKQAAGVSQGVPDEKLCLSPTMSIIEEHQVRLGPKNSSAKRKRAADL
                     GSSPKGKLKKRYKRKSALAIQLFKSDQSPPSTIRLIPGTPDVEASSYEDYFSPDNLKE
                     RNSERLPPEAQQLASPSLFHCRGLSKWERRNMLEMCDFTCIGEKHRSISSISDLISKS
                     ASSLEKPVKEEVNTASTCLLLVETSANDSPGLCSQPGPQLRDDTGPEGSSHPDTLSSS
                     AHHITPLKGNSTETRDPGDGKGSPKEGSTPPASASPEDEVHICNLSLGEDCNVEKSVE
                     EKENIATGYSESVKNGPGRPDPSDSSCTGLVRPQQKPKKSEKEEKAGGFASVRSGVSP
                     QGSVLQYITGVDSQFKSCSFLQPTRTLVMTSMPSEKQTLIIQVVSTLKGFSFAPEVCE
                     TTTHVLVGKSARTLNVLMGIARGCWILSYEWVLLSLELGHWISEEPFELSETFPAAPI
                     CRLERHLSTQQYQGTLFANQPKMFIAPASSPPRAKLCELVLLCGGQVSPAPQLASLII
                     GPYKGKKKARIQYLSEKWVLDSITQHKICDFNNYQLLQ"
ORIGIN      
        1 atgcaggatg gctggagcac ttgttgatga gtctttgttc cctgcagtga ataccgatga
       61 acatctacca aacttaagta gaaaaaaacc tcccagatgt tggagcagtc tcagcagaat
      121 ccatgtgtca gtctgtttga aacatccttg aacatttctc accaaccttt gagttcagat
      181 gaatcctttg ccagtggctc ccactcatct ttcggtgatt cctgtggaga tcaagaaagg
      241 aaactgggaa gatctgctaa tgagatgacc acggtgacat gcccttcctc acctgtgttg
      301 agggcaagca gtttttatgg ctcagcatca cccaaccatc tcaggcagcc acgtcctcag
      361 aaagctccag acagtccttc aaaggagagc atcaactgtc agaaggatgc tacaggtgcg
      421 gtagctgatt ccgagagaaa gcaagctgca ggtgtatctc agggggtgcc tgatgagaag
      481 ctctgtctgt ctcctacgat gtccatcata gaagaacacc aagtacggtt gggacccaag
      541 aattcttctg caaagagaaa aagggcagcg gacttgggtt catctccaaa aggaaaactg
      601 aagaagaggt acaagagaaa gtctgctctg gcaatacagt tattcaagtc cgaccagagc
      661 ccgccgtcca caatcagact cattccggga actcctgacg ttgaggcttc ttcctatgag
      721 gactattttt cccctgataa tctcaaggag aggaattcgg agagacttcc tcctgaggct
      781 cagcaactag caagcccttc tctgttccac tgcagaggtc tctcaaagtg ggagcgaaga
      841 aacatgctgg aaatgtgtga ttttacctgc attggtgaaa agcacagatc catcagcagc
      901 attagtgact taatttcaaa aagtgcctct agtcttgaga aacctgtcaa ggaggaagtg
      961 aatacagctt ctacctgctt gcttttggtg gagacctctg ctaacgacag cccagggctt
     1021 tgcagtcagc ctggccctca gctgagggat gacacaggcc cagagggaag cagccaccct
     1081 gacaccctgt ctagttctgc ccaccacatc acacccttga aaggaaatag tacagaaacc
     1141 agagacccag gtgatggaaa aggctccccc aaagaaggta gcacgcctcc tgcatcagcc
     1201 tctcctgaag atgaagtaca catctgtaat ctcagtttgg gagaggattg taatgtagaa
     1261 aagtctgtag aagaaaagga gaacatagcc acaggatata gtgaaagtgt taaaaatgga
     1321 ccagggcggc cagatccttc agacagctct tgcacaggcc ttgtcagacc tcagcagaaa
     1381 ccaaagaaaa gtgagaaaga agaaaaggca ggtgggtttg catcagtaag aagtggagtc
     1441 tctcctcaag gtagcgtgct gcagtacatc actggagttg actcccaatt taagtcctgc
     1501 tctttcctcc agccaacgag aacattggtc atgacaagca tgccatctga gaagcagacc
     1561 ctcatcatcc aggtggtgag cacactgaaa ggcttttcat tcgcacccga ggtctgcgag
     1621 accaccaccc acgtgctggt agggaagtct gcccgtaccc tgaacgtgct gatgggaatt
     1681 gcccgcggct gctggattct ttcttacgaa tgggtactgt tgtctttaga gttgggccac
     1741 tggatttctg aggagccttt tgaactctct gaaaccttcc ctgcagctcc gatctgccga
     1801 cttgaacgcc atttatctac ccagcaatac caaggaaccc tctttgctaa tcagccgaag
     1861 atgttcatag cgccagccag cagccctccc agagccaaac tgtgtgaact ggtactcctg
     1921 tgtggtggcc aagtcagccc agcccctcag ctggccagcc tcatcattgg tccctacaag
     1981 ggcaagaaga aagcaaggat ccagtacctg tcagagaaat gggtcttaga ttccatcacc
     2041 caacacaaga tctgtgactt taacaactac caactgctac agtgagacat ctacaatgag
     2101 gctgctatcc tcaacactca agaagaacaa ctctggagaa aaggaaccag cagacacctt
     2161 agggcttgaa gtcacatgtc actttgtgtg ctatggtttt tatcttcaga gggtatgtgg
     2221 tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtctaggtg
     2281 tctagagatt aaatccaagg cttgctaagt aagcactgta ctgtggaact acatctccag
     2341 cttttatcct taaaactctt tatgtaactt attcatgact cattgtattt cagagaagtc
     2401 ttgaccagca ccagttgggt actttataca atactaataa tgatcatgat ggaaaggtca
     2461 cagaaccttt gtccttgaga tacttgttcc caattataga atggaagttg atttaaattg
     2521 ctgtagtcct aaacaatcaa atagctccct aactcttctg acttagacgc tgagatcttt
     2581 attagcatgt tgtgtctaga taggaaggac aatcatgcat tattaagatt gcaattatgt
     2641 cccttgagat gcccctcaga acaactaagg aagacaggta tgaacgtttt attcaccgac
     2701 cttgcgaatg tctaccactc tgcctctact gactcccctg aggttcccta aggaaagtca
     2761 gcttctgggg tagagttctg tcaaaggtgt ccaacccatg acccatgtat caaacttgtt
     2821 taagggtacc tagaatgtag ctcatataaa attataaaca tatttaaaag tattaagaga
     2881 tttgtgtgta catatatttc ccccaacccc agcggggttg taactcaatt gcacaattct
     2941 tccgggtgaa ctctagatga ccacgttgta ttacactgtg aaaaggctgg acgtgccatc
     3001 atcaggtcaa tcactcttca gtgtgtcgac acgggagact ggcctggggc ttgcagacct
     3061 cctcttgttg gtgtccccag tgttgggctg tagtctagtg ccaccacatg tcatgctgct
     3121 ccgtcaccta acagacactg agtcccagtg agcttaaaag cagtgctcag ctcactgtag
     3181 ttttctgtgt tacgactcat gtcagctgct gtttccatct caggaagcct caacaccact
     3241 tccaaaacct tgtcatctcc gagataagca attaaagcgt acagtttgtg actctggcat
     3301 tggccttgtt ccctgtacaa ttaatgctct gatggttcat tcatgtcatg tgtgtcagca
     3361 cgtaatttct ttttgttgcc aaacactatc ctatggcatg gatgctctac agacttgctc
     3421 ctcgccccat gagcagagtg caggtgtaaa gcccagtggg aaagcagttg atgatgtcac
     3481 gttgcgttgg gtgatagttg atgatgtcat gttgttctgg gtgatggttg atgatgtcat
     3541 gtgttgctgg atgatagttg atgatgtcac gttgtgctgg gtgatgatag ttgatgatgt
     3601 caggttgtgc ttggtgatca gtagtccagg ctccgtggaa gaagaggatc agatgagggt
     3661 gtgagagacc ccactcatca ccctcctcat cttctgtaat ctgagtaatt ctgtttcccc
     3721 tcacaaatcc atagcttgaa gccatcactt gaagccagaa taatggtgtt taaaaagtgg
     3781 ggtttgggag aaataaaaga gatgcccagc aaagagaagc aataatttta attattagaa
     3841 atcagtctgg tgaaatgtca agctgcactt ataattatgg aaaacactac aatggaaaaa
     3901 atacttacaa tatgatttaa aactaccaac ttattataca attctatagt cagccatgcc
     3961 aagtgtatat gcacagtaca gtgacgtaag tgatttaagt aaaccacagt tgatttttat
     4021 ggttcttgtt aatgctacaa tgcttgtctg gtaatttcaa aatgcaaaat tcaggcacct
     4081 gcagtcaaga ccaaagctcc tgggctccag gggggtgaaa aggaactgaa ataagatgtc
     4141 agcagagctg attcccctga gaaccctagg gagaagccat tcacctgcat gttttctgca
     4201 tgagagtctc ccacccctcc cctctggcgt ttctttcacc ttagtcacgt tgaagtagtg
     4261 tcttgcctat tcactccact atgattcttt ttcccagtgt acccattatc ttcaattgag
     4321 ggataatcac atggactagc catataatct aggatttgtc tttattctac agtcagttga
     4381 gtaccccact ttcccatata cctctgcaaa gcacagttgt gggggctcca ggtcaggaca
     4441 tggatgtctt gacaaggctt tgattctgtg tcctgcactg ctcctcgtct ccccacactg
     4501 aaatcagagg tttgccaaac agctattttc tgataggtca tcccctgtcc tttcaaccga
     4561 tgaaatcatc attgcacctg ccctgatgtc tgacatccca gggtacaagt ttaggagaca
     4621 taccctcatg gaaaagggag ccagggctct gaggtctgta ttatgctgag ttatctccac
     4681 ccaaaacaac tcgtgagtat tcctagcaca gatgagaaaa atgtctacta cacagcccag
     4741 agtccagaca atggagacag tagataatta ttttcagtta ttatgtgctc agcaataatt
     4801 ggatttaatt aatatcaggc tgcaaagtct atcttagagt atctgcggct gcagagtgtt
     4861 gtggtctctg ctctcaatgt cactttcttc tcctaattta aagctgtgaa agttttatgt
     4921 gtgccaagaa gacagtatcg acttttctcc ctcccatatc taaactgtta gctgaaagac
     4981 agtaattaaa atgattgacc tgaaactaaa ccaagagcac acacatattc catgggctaa
     5041 actaatattt tatttggtac aagttcccag cttaggcgtt cctgttttcc caaagcctta
     5101 agaccttcca ggggtgaagc tccacctaga attctaagat gctggcagct gctgcttcat
     5161 taatctggtt tcaatttttt aagtatttgg attcacggct tatctatggg aacaaatgat
     5221 tgttctatct tgaagagtcc agagggaaga tttacggaga aagttaactt catatcccct
     5281 tctgtgggcc agccaatgtg atcccagcca aagctaagga gagaggactg gcagggaaaa
     5341 actccctcga gggctgggcc agcacccaca ggggagagga gagggctcta tcagtcagca
     5401 gactgggcca ggaagagcta aagaagaaga ggctgccaga cctcagggct caacaccaag
     5461 agcaccctat cagctagagg gggcgttcag ccagtgatgt gaaacccaat cattaaatga
     5521 ttgggagcca gttaggggag gaaggaggag gactgtctgt cctgagagtg tgaagctgtg
     5581 ggtggcagga gccatgcaag ggttctgact caggagacca caagcctcct tccaaaagta
     5641 gaacgaggat gctatgtggg acagggccag tagcacagaa ggagctataa ggcccaagat
     5701 agatctcctt tctcagggtg atgaaaagct gtcaccttgg cttgtggcca aagacttaga
     5761 agggactcta caacagcctt ccaccataat cagatcttaa cagaagaatt tgaattctat
     5821 caattttcat gagaaatcct accacagccc tagttaggga ttattggata cagggcccac
     5881 cttatatcct ttgagcccaa attagacctt aactcttagc atagtcgtga acaggtgttc
     5941 ttgccttctt atggatatct aaggttggtt cacaccaaac aaatagggac atttacattt
     6001 attctgtatc actcacatgc accaagcccc aaaggtcagc agtacctagg accacactgc
     6061 tgtcagaggg ctgatggcct cttactatgg cactgcccgt agggtgatgg ccttgaaggg
     6121 gctgaataca tctgagatgg tgtgtagcaa gttgagtgaa gaccaggaga aggtgcaagc
     6181 tagttctata gcggaagggg tgggtttaga aaatgcttcc agtaaagatg gggatctgct
     6241 tgtttttaaa agcataggac tgcagaggga ccagggagaa gctgggcacc gggagtgact
     6301 ggtgaataca gagggcttta gcatggctgg agagtcaagg agcctatgga gaggaatcag
     6361 gaagacacca gacttccgta gagtttgtag aaaaggggga aagcagtagg tttgctttag
     6421 cttggctggt atgtcaagga tggaatgtcc tccaataggt gaaaatagag gaagctttta
     6481 gagccttgtg gtgtaccact gagggagcca gatgctacat atgaatgctt ttaaaagaaa
     6541 aaaaaaatca taaacaaaac caggcatgct gcctcctacc tgccatgtca gtactggaga
     6601 ggctgaagca aggagtgcca tcagattgag gtgagcctgg catacatagt gagaaactat
     6661 ctccaaaagc ccaaattgat tattcacaca aagaaagaaa ttgcaaagat ttaaagcagt
     6721 aacaattgaa ggtaggcaaa ggagatgcaa ctctggggga ctgagggtaa caaagaaaaa
     6781 aatactaaaa actataactc cagaatattt tactgaatta ccaaagattt gagactctac
     6841 atttaaaaaa tatgtcttgt acctgagaag atcaactcaa aacaatgaga ttcctaagat
     6901 ttaaaaataa ataaataaat atccttgggc cattgagcta gccggggctg cagtagcaag
     6961 gcatctgcct ggtggattaa atgacaatag ccctttcctt tcctgcagtt gttgagctgg
     7021 aggtgtaaaa cccaggtgtt ggcttggttt ctagagagcc tctgtcctag ggtggtctcc
     7081 tccctgtata tgaaagcttg gtgtccacct cctcttctca ggacagcagt cataatggac
     7141 tagggctcca ccctccagac ctcctatgtc tctagtcacc tgttacatct cttctagtag
     7201 tgactcgctt ggcaggccta aaaacctaga agcagttttg aggcagagtc tcaaggaaac
     7261 tcagcctctt agaactttga cattctcata gctagaatgt ctcagatttg tccctgtaat
     7321 attgtggagt gtcttacatg ttttcttata gtattttact ggataagagt tagaaatctc
     7381 gccgggcatg gtgatgcaca cctttaatcc cagcactcag gaagcagagg caggcggatt
     7441 tctgaggaca gcctggtcta cagagtgaat tccaggacag ccagggctat acagagaaac
     7501 cctgtctcga aaaaacaaaa aaccaaaaaa acaaaacaaa acaaaaaaaa aacaaacaac
     7561 aacaaaaaaa acagagaaat ctcagggcaa gcttagcaaa gtatatttag aatctttatt
     7621 acagccagtt atagcagaca acattgtata ttagaagcaa gttggtgaat tctcttgaca
     7681 aatggagatt ccccacagat acttaaaaga acagccaagt tactctcata tgcaagaatt
     7741 taccaaggcc taggaaatag gggggttgtg gtattgcatt attcatgaga aggtctgcta
     7801 gagcagaacc ccctggtgct agctttcaca agactcaaag gagtaacaca aattgtgact
     7861 agggtgtgaa atccttacct gtcattaggt gaccctaggc agggctgttt tatctttact
     7921 gtaaatgtta cctggttcct gtaagttcct tttgaagtca ttcctttgtt ttgtgtcagg
     7981 taacttcaat gtactttgcc tgctgtgaca tcctacccct ttgttttctg tatcatataa
     8041 gactagtgtt cactttgtga cattactttg tcattcgccc acctgcaacc agagacccat
     8101 tcctagcaga tagcagatcc aaaaaaggag atagtctgca acagtcacca ccttaaagac
     8161 cctgtctcca gaatcagtca agttcaacgt ctggactttg acattgactt agtgtgtata
     8221 tataagttta tataacatta taaacacatg catgtatata tatacagtta atagacatgc
     8281 attatgcata catagtaaga agcaaatggc atataagaac taaatttttt cataacaatg
     8341 tataagaaag tgaataatgt tatttaagat cttcaaaaga acacatgact taaaatttta
     8401 tatttaaaag ctaactctta agcaaatatg acatggcaaa ctcataactg aatgccagga
     8461 cccaggactg ttattgccat ggtcttggag gaagagtcca ctgggaggca aagtctaaac
     8521 aagcaagatg aggagtcagt gaggctgtgg tggttaggta tggaaataga ggtatacaaa
     8581 tagagataag caaataggca gagagataaa accaatgcct aggactgaaa ggagtggtag
     8641 agtgggtggg ggctagaagc tctgatagag gaagacttag atatgtacac agcaataaaa
     8701 cattttcagt gtt
//
