LOCUS       NM_178076               5228 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus mcf.2 transforming sequence-like (Mcf2l), transcript
            variant 1, mRNA.
ACCESSION   NM_178076 XM_134017
VERSION     NM_178076.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5228)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5228)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5228)
  AUTHORS   Hoffmann,S., Schmitteckert,S., Raedecke,K., Rheinert,D.,
            Diebold,S., Roeth,R., Weiss,B., Granzow,M., Niesler,B.,
            Griesbeck,A., Eckstein,V., Zimmermann,W.H., Just,S. and
            Rappold,G.A.
  TITLE     Network-driven discovery yields new insight into Shox2-dependent
            cardiac rhythm control
  JOURNAL   Biochim Biophys Acta Gene Regul Mech 1864 (4-5), 194702 (2021)
   PUBMED   33706013
REFERENCE   4  (bases 1 to 5228)
  AUTHORS   Mao,J.H., Sui,Y.X., Ao,S., Wang,Y., Liu,Y. and Leng,H.
  TITLE     miR-140-3p exhibits repressive functions on preosteoblast viability
            and differentiation by downregulating MCF2L in osteoporosis
  JOURNAL   In Vitro Cell Dev Biol Anim 56 (1), 49-58 (2020)
   PUBMED   31732956
  REMARK    GeneRIF: miR-140-3p exhibits repressive functions on preosteoblast
            viability and differentiation by downregulating MCF2L in
            osteoporosis.
REFERENCE   5  (bases 1 to 5228)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 5228)
  AUTHORS   VanBuren,V., Piao,Y., Dudekula,D.B., Qian,Y., Carter,M.G.,
            Martin,P.R., Stagg,C.A., Bassey,U.C., Aiba,K., Hamatani,T.,
            Kargul,G.J., Luo,A.G., Kelso,J., Hide,W. and Ko,M.S.
  TITLE     Assembly, verification, and initial annotation of the NIA mouse
            7.4K cDNA clone set
  JOURNAL   Genome Res 12 (12), 1999-2003 (2002)
   PUBMED   12466305
REFERENCE   7  (bases 1 to 5228)
  AUTHORS   Snyder,J.T., Worthylake,D.K., Rossman,K.L., Betts,L., Pruitt,W.M.,
            Siderovski,D.P., Der,C.J. and Sondek,J.
  TITLE     Structural basis for the selective activation of Rho GTPases by Dbl
            exchange factors
  JOURNAL   Nat Struct Biol 9 (6), 468-475 (2002)
   PUBMED   12006984
REFERENCE   8  (bases 1 to 5228)
  AUTHORS   Rossman,K.L., Worthylake,D.K., Snyder,J.T., Siderovski,D.P.,
            Campbell,S.L. and Sondek,J.
  TITLE     A crystallographic view of interactions between Dbs and Cdc42: PH
            domain-assisted guanine nucleotide exchange
  JOURNAL   EMBO J 21 (6), 1315-1326 (2002)
   PUBMED   11889037
REFERENCE   9  (bases 1 to 5228)
  AUTHORS   Lorenzi,M.V., Castagnino,P., Chen,Q., Hori,Y. and Miki,T.
  TITLE     Distinct expression patterns and transforming properties of
            multiple isoforms of Ost, an exchange factor for RhoA and Cdc42
  JOURNAL   Oncogene 18 (33), 4742-4755 (1999)
   PUBMED   10467422
REFERENCE   10 (bases 1 to 5228)
  AUTHORS   Whitehead,I., Kirk,H. and Kay,R.
  TITLE     Retroviral transduction and oncogenic selection of a cDNA encoding
            Dbs, a homolog of the Dbl guanine nucleotide exchange factor
  JOURNAL   Oncogene 10 (4), 713-721 (1995)
   PUBMED   7862449
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC127308.3.
            
            On Jun 25, 2019 this sequence version replaced NM_178076.3.
            
            Transcript Variant: This variant (1) encodes isoform 1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            CCDS Note: The coding region has been updated to extend the
            N-terminus to one that is supported by available conservation data.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC058622.1, SRR9219380.27857.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-144               AC127308.3         44709-44852
            145-228             AC127308.3         91962-92045
            229-343             AC127308.3         101777-101891
            344-434             AC127308.3         113658-113748
            435-554             AC127308.3         122627-122746
            555-671             AC127308.3         125408-125524
            672-821             AC127308.3         126044-126193
            822-946             AC127308.3         127167-127291
            947-1061            AC127308.3         128747-128861
            1062-1181           AC127308.3         129541-129660
            1182-1373           AC127308.3         130080-130271
            1374-1565           AC127308.3         130609-130800
            1566-1725           AC127308.3         131436-131595
            1726-1799           AC127308.3         132373-132446
            1800-1876           AC127308.3         132683-132759
            1877-1943           AC127308.3         134248-134314
            1944-2059           AC127308.3         135523-135638
            2060-2129           AC127308.3         136483-136552
            2130-2222           AC127308.3         138265-138357
            2223-2315           AC127308.3         138452-138544
            2316-2441           AC127308.3         139214-139339
            2442-2663           AC127308.3         140177-140398
            2664-2756           AC127308.3         140527-140619
            2757-2835           AC127308.3         141599-141677
            2836-2902           AC127308.3         141796-141862
            2903-3018           AC127308.3         142333-142448
            3019-3111           AC127308.3         142713-142805
            3112-3186           AC127308.3         143617-143691
            3187-3308           AC127308.3         146145-146266
            3309-3421           AC127308.3         146859-146971
            3422-5228           AC127308.3         147494-149300
FEATURES             Location/Qualifiers
     source          1..5228
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 5.73 cM"
     gene            1..5228
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /note="mcf.2 transforming sequence-like"
                     /db_xref="GeneID:17207"
                     /db_xref="MGI:MGI:103263"
     exon            1..144
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     CDS             66..3593
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /note="isoform 1 is encoded by transcript variant 1;
                     guanine nucleotide exchange factor DBS; Ost gamma; guanine
                     nucleotide exchange factor OSTIII; exchange factor for
                     RhoA and Cdc42; DBL's big sister; MCF2-transforming
                     sequence-like protein"
                     /codon_start=1
                     /product="guanine nucleotide exchange factor DBS isoform
                     1"
                     /protein_id="NP_835177.2"
                     /db_xref="CCDS:CCDS40225.2"
                     /db_xref="GeneID:17207"
                     /db_xref="MGI:MGI:103263"
                     /translation="MRFWLRNEEMALEEMVQRLNAVSKNTDEIMHQDIVPLCAADIQE
                     QLKKRFAYLSGGRGQDGSPVITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFI
                     LVIDRRQDKWTSVKASVLRIAASFPANLQLVLVLRPTGFFQRTLSDIAFKFNRDEFKM
                     KVPVMMLSSVPELHGYIDKSQLTEDLGGTLDYCHSRWLCHRTAIESFALMVKQTAQML
                     QAFGTELAETELPNDVQSTSLVLSAHTEKKAKVKEDLQLALKEGNSILESLREPLAES
                     AAHSVNQDQLDNQATVQRLLAQLNETEAAFDEFWAKHQQKLEQCLQLRHFEQGFREVK
                     TTLDSMSQKIAAFTDVGNSLAHVQHLLKDLTAFEEKSSVAVDKARALSLEGQQLIENR
                     HYAVDSIHPKCEELQHLCDHFASEVTRRRGLLSKSLELHSLLETSMKWSDEGIFLLAS
                     QPVDKCQSQDGAEAALQEIEKFLETGAENKIQELNEIYKEYECILNQDLLEHVQKVFQ
                     KQESTEEMFHRRQASLKKLAAKQTRPVQPVAPRPEALTKSPSPSPGSWRSSENSSSEG
                     NALRRGPYRRAKSEMSEPRQGRTSSTGEEEESLAILRRHVMNELLDTERAYVEELLCV
                     LEGYAAEMDNPLMAHLISTGLQNKKNILFGNMEEIYHFHNRIFLRELESCIDCPELVG
                     RCFLERMEEFQIYEKYCQNKPRSESLWRQCSDCPFFQECQKKLDHKLSLDSYLLKPVQ
                     RITKYQLLLKEMLKYSKHCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDL
                     GKLLMQGSFSVWTDHKKGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKA
                     PSYSYKQSLNMTAVGITENVKGDTKKFEIWYNAREEVYIIQAPTPEIKAAWVNEIRKV
                     LTSQLQACREASQHRALEQSHSLPLPTPSSTSPTKGNTRNVKKLEDRKTDPLSLEGYV
                     SSSLPKPPEKGKDDAVPSSTSESSALSRKRFTLQGLANLKGQKASPTSPDKKAKRHEV
                     KSDPTPFGLRGWSKTSHSLEAPEEDGGWSSAEELINSSDAEEDGGVGPKKLVPGKYTV
                     VMDDEKGGPDTLAMRSGDMVEVVEEGAEGLWYVRDLTSSKEGWVPASSLSTLLGKSSS
                     AQCLSSSGKIHCARQLCPEPAEILSPEPV"
     exon            145..228
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            229..343
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            344..434
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            435..554
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            555..671
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            672..821
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            822..946
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            947..1061
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            1062..1181
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            1182..1373
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            1374..1565
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            1566..1725
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            1726..1799
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            1800..1876
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            1877..1943
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            1944..2059
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            2060..2129
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            2130..2222
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            2223..2315
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            2316..2441
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            2442..2663
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            2664..2756
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            2757..2835
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            2836..2902
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            2903..3018
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            3019..3111
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            3112..3186
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            3187..3308
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            3309..3421
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     exon            3422..5228
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5210..5215
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /note="hexamer: AATAAA"
     polyA_site      5228
                     /gene="Mcf2l"
                     /gene_synonym="C130040G20Rik; Dbs; mKIAA0362; Ost"
                     /note="major polyA site"
ORIGIN      
        1 acccgacagc acctctggtg cagcggagga cgatcttctg gggatcggtt ttgttgaatc
       61 ggaggatgag gttttggctg agaaatgaag agatggccct agaagaaatg gtgcagagat
      121 taaacgcggt ttccaagaac actgatgaaa tcatgcacca ggacatcgtc ccgctctgtg
      181 ccgctgacat ccaggagcag ctgaagaagc gctttgctta cctgtctggt gggcggggac
      241 aggacggaag cccagtcatc accttccctg actacccagc cttcagcgag atcccggaca
      301 aggagttcca gaatgtcatg acctatctca ccagcatccc cagtttgcaa gatgctggca
      361 ttggattcat cttggtcata gaccgaaggc aggacaaatg gacctctgtg aaggcatccg
      421 tcctgcggat agccgcatct ttcccagcca acctgcagct tgtccttgtt cttcggccca
      481 cgggcttttt ccagaggact ctctcggaca ttgccttcaa gttcaacaga gatgagttta
      541 agatgaaagt gccggtcatg atgctaagct cagtgccaga actacacggc tacattgata
      601 agtcgcagct gaccgaggac ctcgggggga ccctggacta ctgccactcc aggtggctgt
      661 gccaccgcac agcaattgaa agcttcgccc tgatggtgaa gcagacagcc cagatgctgc
      721 aggcctttgg gaccgagctg gctgaaacag agctgccgaa tgacgtccag tcaaccagcc
      781 tggtgctcag cgcacacaca gagaagaagg ccaaagtgaa ggaagatctg cagttagcac
      841 tgaaggaggg gaacagcatc ctggagagcc tcagagagcc actggctgag agcgcggccc
      901 acagtgtgaa ccaggaccag ctggacaatc aggccaccgt gcagaggctc ctggcccagc
      961 tgaatgagac ggaggctgcc tttgacgaat tctgggcaaa gcatcagcag aagctggaac
     1021 agtgcctgca gctgcggcat tttgagcaag gtttccggga ggtcaaaacc accttggatt
     1081 ccatgtccca gaagatagct gctttcacgg atgttggcaa cagcctggcc cacgtgcagc
     1141 accttctgaa ggacttgacc gcctttgagg agaagtccag tgtggctgtg gacaaggccc
     1201 gcgccctgtc actggaaggt cagcagctga ttgagaacag gcactacgct gtggactcca
     1261 tccaccccaa gtgtgaagag ctccagcacc tctgtgacca cttcgcctct gaggtcacca
     1321 ggaggcgggg cctgctcagc aagtccttgg agctgcatag cctcctggag acgtccatga
     1381 agtggagcga cgaggggatc ttcctgctgg cctcgcagcc tgtggacaaa tgccagtccc
     1441 aggatggcgc agaggcggcc ctccaggaga ttgagaagtt tctggagacc ggtgcagaaa
     1501 ataagattca ggagctcaat gagatttaca aggaatacga atgcatcctc aaccaggacc
     1561 ttctggaaca cgtgcaaaaa gtctttcaga agcaagaaag cacggaggag atgttccacc
     1621 gcaggcaagc cagcctgaag aaactggcag ccaagcagac acggcctgtg cagcccgtgg
     1681 ccccccgacc agaggcgctt accaagtcgc cctccccctc gccaggctcc tggcgaagct
     1741 ctgagaactc cagctctgag ggcaacgcac tccgcagagg gccctacagg agagccaaga
     1801 gcgaaatgag tgaaccccgg cagggccgca ccagctccac aggggaagag gaagagagcc
     1861 tggccatcct gcgcagacac gtgatgaatg agcttctgga caccgagcgg gcctacgtgg
     1921 aggagctgct ctgtgtctta gagggctatg ccgcagagat ggataacccc ttgatggcac
     1981 acctcatctc aacaggcctg caaaacaaga agaacattct gtttggaaac atggaggaaa
     2041 tctatcattt tcacaacaga atattcctgc gggagctgga gagctgcata gactgcccag
     2101 agctggtggg gaggtgcttt ctggaaagga tggaggagtt ccagatctat gagaagtact
     2161 gtcagaacaa gccacgctct gagagcctgt ggaggcagtg ctctgactgc cccttcttcc
     2221 aggagtgtca gaagaagctg gaccacaagc tgagcctgga ctcctacctg ctgaaacctg
     2281 tgcagaggat aaccaagtac cagctgctgc tcaaggaaat gctgaagtac agcaagcact
     2341 gtgaaggggc agaggacctg caggaggcgc tgagctccat cctgggcatc ctcaaggctg
     2401 tgaacgactc catgcatctc atcgccatca ctggctatga tggaaacctt ggcgacctgg
     2461 ggaagctgct gatgcaaggt tccttcagcg tgtggacaga ccacaagaag ggccacacca
     2521 aagtgaagga gctagccagg ttcaagccca tgcagcggca cctgtttctg cacgagaagg
     2581 ccgtcctctt ctgcaagaag agggaggaga atggggaggg atacgagaag gctccttcct
     2641 acagctacaa gcagtccttg aatatgacgg ctgtcggcat cacagagaac gtgaagggtg
     2701 acaccaagaa gttcgagatc tggtacaacg caagggagga ggtttatatc attcaggcgc
     2761 caacccccga gattaaagca gcgtgggtga atgagattcg gaaggtgctg accagccagc
     2821 tgcaggcttg ccgggaggcc agccagcacc gagccctgga gcagtcccac agccttcctt
     2881 tgcccacgcc atccagcacc agtcccacaa aagggaacac aagaaatgtc aagaagctcg
     2941 aagaccggaa gacggacccg ctcagcctgg aaggctacgt gagctcatcg ttaccaaagc
     3001 cccctgagaa gggcaaagac gatgcggtcc ctagttctac ctctgaaagc tctgcgcttt
     3061 ccagaaagcg cttcacgctg cagggcttgg ctaacctcaa aggtcagaaa gcctctccga
     3121 ccagtcctga caaaaaagct aagcggcacg aagtaaagag cgacccgact ccctttggtt
     3181 tgcgaggctg gagcaaaaca tcccactccc tggaggcccc tgaggaggac ggaggctggt
     3241 ccagtgctga ggaactcatc aactcatctg atgctgagga agacggtgga gtgggcccta
     3301 agaagctggt gccgggtaaa tacacagtgg tgatggatga tgagaaaggg ggccctgaca
     3361 cccttgccat gaggagtgga gatatggtgg aggtggtgga agaaggcgct gagggcctct
     3421 ggtatgttcg ggacctgacc agcagcaagg agggatgggt gccagccagc agcctatcca
     3481 ccctcctggg caaatccagt tcagcccagt gtctgagcag ctcaggtaag atccactgtg
     3541 cgcgccagct gtgccctgag cctgccgaga tcctcagccc agagcccgtt taaaagcaga
     3601 ggggtttcta ggtgtgcaga gcaaagggcc agagccgaag cctgtctcca ctggtttccc
     3661 gcagactcca gcccagggtc agccgtgctg agcagctcat ccagcttcag cgagggctac
     3721 cctgctccct tctccgagct ccagggatag tggccaggcc cctgtggcag gcactcgagg
     3781 tcaccgtgca gtagaccagc atgcaaatct ctaagttttt tggttttttt ttatttttaa
     3841 tttttatttt tgcttgggct tgcttagttt gggaggggat ggtgctccga gatctctgga
     3901 aacaggaggc ccctgtcagc catgggcttc agaggacatt ggggccttgg aaccaggacc
     3961 ccactgcata tgcagatgcc aggagacaac agttcaccac caaagcttct tcagagactc
     4021 cagagtggac agaggcgggg ctgtgggtca ggagacccct gtgcaggaag ctgggaggca
     4081 gccaacagcc cctgctgtgc agcctctcta aggtgtcctg gcctctctgg tgctttctac
     4141 ggcaacacga ccctgaggaa gccacttcta acaggagtga acagtttgct accaacagcc
     4201 taaggggggg tcaagggact ctcgtctttt ataagttttt gatttttttt aaacagggat
     4261 taaccccatg gccatttttt gtggtactct ggcctcaaaa ctttaaccaa gaatcactgt
     4321 gtttacatga aatgacaatt tgatactgta tttgatataa aactattttt tgttactggg
     4381 gtttacatca aagcacgttg tttatacaac taactgattt ctggggcact ctcgctgaga
     4441 cctggcactc cctggaatac aggtgcagga aggcctggtc agccaggggg tgtgtcctcc
     4501 tgggcagcca gggggcgtgt cctccaccaa aagcagttgg aaatcattga gagtcttgca
     4561 tctgcatagg tttcgttttc acaagaaatg taaagtataa tttaaaatat tagccttctt
     4621 ttctacaata taaaggagac tctctgtttt ttaaaagaac atcattaaat taggatattt
     4681 ttattatttt taaagaaaat gtataactcc atgctgtcag tcatcctcag caactcaggc
     4741 actggctgcc tctccacgtc agggcaggcc ccacttcccc tctcctagcc ccgtccactc
     4801 tgccctacag caggaggggc tgcagctgag cttggggtgg gggacgggga tctgcagcct
     4861 ccattcaagt cacggcagaa ctgccacaaa ctgttgtttt ccgctttttt gtgtgtttca
     4921 gaaacaaatt ctgttctttg gaaactctct gtgcctagta gggcagatat ttttatatgt
     4981 gtgtatatat gttcacgtgt gtacatagga tcttggtgta aaggatgtat ttatggtctc
     5041 acgctgctga acatgtgtca ctttacggtc cctccctgtc tcctcaccct gctgccatgg
     5101 gaggccaccg aggctcgttc accactgtat gtccaggaaa aacaccctcc tcccctgccc
     5161 tatggcttgc aaagccatta ctggctacac cttcagagaa tggtaataaa ataaaaaacg
     5221 tgcaaaga
//
