LOCUS       XM_011248450            4207 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus membrane-bound transcription factor
            peptidase, site 1 (Mbtps1), transcript variant X2, mRNA.
ACCESSION   XM_011248450
VERSION     XM_011248450.3
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000074.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Sep 21, 2020 this sequence version replaced XM_011248450.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4207
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="8"
     gene            1..4207
                     /gene="Mbtps1"
                     /gene_synonym="0610038M03Rik; mKIAA0091; S1P; SKI-1; Ski1"
                     /note="membrane-bound transcription factor peptidase, site
                     1; Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 13 mRNAs, 95 ESTs, 875 long SRA reads, 6
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 53 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:56453"
                     /db_xref="MGI:MGI:1927235"
     CDS             425..3583
                     /gene="Mbtps1"
                     /gene_synonym="0610038M03Rik; mKIAA0091; S1P; SKI-1; Ski1"
                     /codon_start=1
                     /product="membrane-bound transcription factor site-1
                     protease isoform X1"
                     /protein_id="XP_011246752.1"
                     /db_xref="GeneID:56453"
                     /db_xref="MGI:MGI:1927235"
                     /translation="MKLVSTWLLVLVVLLCGKRHLGDRLGTRALEKAPCPSCSHLTLK
                     VEFSSTVVEYEYIVAFNGYFTAKARNSFISSALKSSEVENWRIIPRNNPSSDYPSDFE
                     VIQIKEKQKAGLLTLEDHPNIKRVTPQRKVFRSLKFAESNPIVPCNETRWSQKWQSSR
                     PLKRASLSLGSGFWHATGRHSSRRLLRAIPRQVAQTLQADVLWQMGYTGANVRVAVFD
                     TGLSEKHPHFKNVKERTNWTNERTLDDGLGHGTFVAGVIASMRECQGFAPDAELHIFR
                     VFTNNQVSYTSWFLDAFNYAILKKMDVLNLSIGGPDFMDHPFVDKVWELTANNVIMVS
                     AIGNDGPLYGTLNNPADQMDVIGVGGIDFEDNIARFSSRGMTTWELPGGYGRVKPDIV
                     TYGAGVRGSGVKGGCRALSGTSVASPVVAGAVTLLVSTVQKRELVNPASVKQALIASA
                     RRLPGVNMFEQGHGKLDLLRAYQILSSYKPQASLSPSYIDLTECPYMWPYCSQPIYYG
                     GMPTIVNVTILNGMGVTGRIVDKPEWRPYLPQNGDNIEVAFSYSSVLWPWSGYLAISI
                     SVTKKAASWEGIAQGHIMITVASPAETELHSGAEHTSTVKLPIKVKIIPTPPRSKRVL
                     WDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHVHTNFRDMYQHLRSMGYFVEVLGAPF
                     TCFDATQYGTLLLVDSEEEYFPEEIAKLRRDVDNGLSLVIFSDWYNTSVMRKVKFYDE
                     NTRQWWMPDTGGANIPALNELLSVWNMGFSDGLYEGEFVLANHDMYYASGCSIAKFPE
                     DGVVITQTFKDQGLEVLKQETAVVENVPILGLYQIPSEGGGRIVLYGDSNCLDDSHRQ
                     KDCFWLLDALLQYTSYGVTPPSLSHSGNRQRPPSGAGLAPPERMEGNHLHRYSKVLEA
                     HLGDPKPRPLPACPHLSWAKPQPLNETAPSNLWKHQKLLSIDLDKVVLPNFRSNRPQV
                     RPLSPGESGAWDIPGGIMPGRYNQEVGQTIPVFAFLGAMVALAFFVVQISKAKSRPKR
                     RRPRAKRPQLAQQAHPARTPSV"
ORIGIN      
        1 ggtgcgcaag cgccgttcgc ctccgcaggg ccctgcggtc gcgagccccg gggaaccgag
       61 ctgcagctca gtgcacatcg cggctcggac tcgcatttgc tgtccgctac agagcggtgg
      121 attgggcatc ctgctagatt tgggtctgtg gcgcaaatgg agtttaggac tcagtggact
      181 cggcctcaat gagagaagcc cctgtccaag atggagaaga agcggagaaa gaaatgaaag
      241 cctctctttg ggccaaaccg tgggtgacca tgggactgag gttttcttta tgttggacaa
      301 gtctgtagga tggctgatca gtaaggctgc agcttttagc cagaacagaa acccacttct
      361 gatcaaggaa gagcctcgtg cgatttgaat ttatgcaatt ttctgaccat attcactgag
      421 gaccatgaag ctcgtcagca cctggcttct tgtgctggtg gttttgctct gtgggaaacg
      481 gcacctgggc gacaggctgg ggacgagagc tttggaaaag gccccgtgcc ccagctgctc
      541 ccacctgact ttgaaggtgg aattctcttc aactgtggtg gagtacgaat atattgtggc
      601 tttcaacgga tacttcacag ccaaagctag aaactcattt atttcaagtg ctctgaaaag
      661 cagtgaagtg gaaaactgga gaataatacc tcggaacaac ccatccagtg actaccctag
      721 tgattttgag gtgattcaga taaaagagaa gcagaaggcg gggctgctca cacttgaaga
      781 tcaccccaac atcaagcggg tgacacccca gcggaaagtc tttcgttccc tcaagtttgc
      841 tgaatccaac cccatcgtgc cctgtaatga aacccggtgg agccagaagt ggcagtcatc
      901 acgtcccctg aaaagagcca gtctctccct gggctctgga ttctggcatg caacaggaag
      961 acattcaagt cggcgattgc tgagagccat tcctcgccag gtcgcccaga cactgcaggc
     1021 agatgtgctg tggcagatgg gatacacagg tgctaatgtc agagttgctg tttttgatac
     1081 tgggctcagt gagaagcatc cgcattttaa gaatgtgaag gagagaacca actggaccaa
     1141 tgagcggacc ctggatgatg ggctaggcca tggcacattc gttgcaggtg tgattgccag
     1201 catgagggag tgccaaggat ttgctccaga tgcagagctg cacatcttca gggtctttac
     1261 caacaatcag gtgtcttaca catcttggtt tctggatgcc ttcaactatg ccatcctaaa
     1321 gaagatggac gttctcaacc ttagcatcgg tgggcccgac ttcatggatc atccgtttgt
     1381 tgacaaggtg tgggaattaa cagctaacaa tgtaattatg gtttctgcta ttggcaatga
     1441 tggacctctc tatggcactc tgaataaccc tgctgatcag atggatgtga ttggagtggg
     1501 tggcattgac tttgaagata acatcgctcg cttttcttcc aggggaatga ctacctggga
     1561 attaccagga ggctatggtc gtgtgaagcc tgacattgtc acctatggtg ctggagtgcg
     1621 gggttccggt gtgaaagggg gctgccgtgc actctcaggg accagtgtcg cttccccagt
     1681 ggtcgctggg gccgtcacct tgttagtaag cacagtacag aagcgggagc tggtgaatcc
     1741 tgccagtgtg aagcaagctt tgatagcgtc agcccggaga cttcctgggg tcaacatgtt
     1801 cgagcaaggt catggcaagt tggatctgct gcgagcttat cagatcctca gcagctataa
     1861 accgcaggca agcctgagtc ctagctacat cgacctgact gagtgtccct acatgtggcc
     1921 ctactgctcc cagcctatct actatggagg aatgccaaca atcgttaatg tcaccatcct
     1981 caatggcatg ggcgtcacag gaagaattgt ggataagcct gagtggcgac cctatttacc
     2041 acagaatgga gacaacattg aagtggcctt ctcctactcc tcagtgttgt ggccctggtc
     2101 aggttacctt gccatctcca tttctgtgac caagaaggca gcttcctggg aaggcatcgc
     2161 tcagggccac atcatgatca cagtggcgtc cccagcagag acagagttac acagtggtgc
     2221 ggagcacact tccaccgtga agctgcccat caaggtgaag atcattccca cccctcctcg
     2281 gagcaagaga gtcctctggg accagtacca caacctccgc tacccacctg gctacttccc
     2341 cagggacaac ttgcggatga agaatgaccc tttagactgg aatggcgacc acgtccacac
     2401 caacttcagg gacatgtacc agcatctgcg cagcatgggc tacttcgtgg aggtgctcgg
     2461 cgccccattc acatgttttg acgccacaca gtatggcact ttgctgctgg tggacagtga
     2521 ggaagagtac ttccctgagg agattgctaa gctgaggagg gatgtggaca atggcctttc
     2581 cctcgtcatc ttcagtgact ggtacaacac ttctgttatg agaaaagtga agttttatga
     2641 tgaaaacacc aggcagtggt ggatgccaga caccggagga gcgaacatcc cagctctgaa
     2701 tgagctgctg tctgtgtgga acatggggtt cagtgacggc ctatatgaag gggagtttgt
     2761 cctggcaaac catgacatgt actatgcgtc ggggtgcagc atcgccaagt ttccagaaga
     2821 tggcgtcgtg atcacacaga ctttcaagga ccaaggattg gaggtcttaa aacaagagac
     2881 agcagttgtg gaaaatgttc ccattttggg gctttatcag attccatctg aaggtggagg
     2941 ccggatcgtg ctgtatggag actccaactg cttggatgac agtcacagac agaaggactg
     3001 cttttggctt ctggatgcgc tccttcagta cacatcctat ggcgtgaccc ctcccagcct
     3061 cagccattca gggaaccggc agcgcccacc tagcggagcc ggcttggccc ctcctgaaag
     3121 gatggaagga aaccacctcc atcggtactc caaagttctt gaagcccact tgggagaccc
     3181 gaaacctcgg cccctgccag cctgtccaca tttgtcatgg gccaagccac agcctttgaa
     3241 tgagacggca cccagtaatc tttggaaaca tcagaagctg ctctccattg acctggacaa
     3301 agtagtgtta cccaactttc gatccaatcg ccctcaagtg agacctttgt cccctggaga
     3361 gagtggtgcc tgggacattc ctggagggat catgcctggc cgctacaacc aggaggtggg
     3421 acagaccatc cccgtcttcg ccttcctcgg agccatggtg gccctggcct tctttgtggt
     3481 acagatcagc aaggccaaga gccggccgaa gcggaggagg cccagggcaa agcgtccaca
     3541 acttgcacag caggcccacc ctgcaaggac cccatcagtg tgagcatcgc agtagccagc
     3601 cacagaagct aacaagcctt gaaccactct ggtggccaca cagcgcctca gagagcattc
     3661 tgggaagtgc ctgtttccga ggaaccctgt ctccagcttg tggctatctt actgtgttct
     3721 gcccaggcac ctgatgaggt acatcctgca gtgcctctct gtgcttggct ctggcagaag
     3781 gcacccagtg acatcaggca tcaggcccag tgacagtgca ccaaagacac agagcctgga
     3841 agggctgtcg ggacatactt tctacataac gctacaaccc tgaccaagca aagacatgct
     3901 tgttacaggc tattttctat atttattgtg ggagagtcac tttaaagact gtgctagttg
     3961 gaaacagagc tgttgctgtt gtcagtcgag tgcagttttc tgcagcgatg tcataaggag
     4021 tcagattccg tgacctcctc tttgatggag gacacactga actgaagggg acttgcgcgg
     4081 atgtgggaga tgcaagcctt cgctttattt ttttataact atcaactgcc atcatgtttt
     4141 gtaatttggg gatcttgatt tcaccgttgt tggtgaagga aattttcaat aaatatgcat
     4201 aacctta
//
