LOCUS       NM_134163               8829 bp    mRNA    linear   ROD 06-JUN-2024
DEFINITION  Mus musculus muscleblind like splicing factor 3 (Mbnl3), transcript
            variant 1, mRNA.
ACCESSION   NM_134163
VERSION     NM_134163.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8829)
  AUTHORS   Nutter,C.A., Kidd,B.M., Carter,H.A., Hamel,J.I., Mackie,P.M.,
            Kumbkarni,N., Davenport,M.L., Tuyn,D.M., Gopinath,A., Creigh,P.D.,
            Sznajder,L.J., Wang,E.T., Ranum,L.P.W., Khoshbouei,H., Day,J.W.,
            Sampson,J.B., Prokop,S. and Swanson,M.S.
  TITLE     Choroid plexus mis-splicing and altered cerebrospinal fluid
            composition in myotonic dystrophy type 1
  JOURNAL   Brain 146 (10), 4217-4232 (2023)
   PUBMED   37143315
REFERENCE   2  (bases 1 to 8829)
  AUTHORS   Spruce,T., Plass,M., Gohr,A., Ray,D., Martinez de Lagran,M.,
            Rot,G., Novoa,A., Burguera,D., Permanyer,J., Miret,M., Zheng,H.,
            Swanson,M.S., Morris,Q., Mallo,M., Dierssen,M., Hughes,T.R.,
            Pernaute,B. and Irimia,M.
  TITLE     The X-linked splicing regulator MBNL3 has been co-opted to restrict
            placental growth in eutherians
  JOURNAL   PLoS Biol 20 (4), e3001615 (2022)
   PUBMED   35476669
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 8829)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 8829)
  AUTHORS   Sznajder,L.J., Scotti,M.M., Shin,J., Taylor,K., Ivankovic,F.,
            Nutter,C.A., Aslam,F.N., Subramony,S.H., Ranum,L.P.W. and
            Swanson,M.S.
  TITLE     Loss of MBNL1 induces RNA misprocessing in the thymus and
            peripheral blood
  JOURNAL   Nat Commun 11 (1), 2022 (2020)
   PUBMED   32332745
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 8829)
  AUTHORS   Thomas,J.D., Sznajder,L.J., Bardhi,O., Aslam,F.N.,
            Anastasiadis,Z.P., Scotti,M.M., Nishino,I., Nakamori,M., Wang,E.T.
            and Swanson,M.S.
  TITLE     Disrupted prenatal RNA processing and myogenesis in congenital
            myotonic dystrophy
  JOURNAL   Genes Dev 31 (11), 1122-1133 (2017)
   PUBMED   28698297
REFERENCE   6  (bases 1 to 8829)
  AUTHORS   Kino,Y., Washizu,C., Oma,Y., Onishi,H., Nezu,Y., Sasagawa,N.,
            Nukina,N. and Ishiura,S.
  TITLE     MBNL and CELF proteins regulate alternative splicing of the
            skeletal muscle chloride channel CLCN1
  JOURNAL   Nucleic Acids Res 37 (19), 6477-6490 (2009)
   PUBMED   19720736
REFERENCE   7  (bases 1 to 8829)
  AUTHORS   Liang,J., Song,W., Tromp,G., Kolattukudy,P.E. and Fu,M.
  TITLE     Genome-wide survey and expression profiling of CCCH-zinc finger
            family reveals a functional module in macrophage activation
  JOURNAL   PLoS One 3 (8), e2880 (2008)
   PUBMED   18682727
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 8829)
  AUTHORS   Lee,K.S., Smith,K., Amieux,P.S. and Wang,E.H.
  TITLE     MBNL3/CHCR prevents myogenic differentiation by inhibiting
            MyoD-dependent gene transcription
  JOURNAL   Differentiation 76 (3), 299-309 (2008)
   PUBMED   17697127
REFERENCE   9  (bases 1 to 8829)
  AUTHORS   Kanadia,R.N., Urbinati,C.R., Crusselle,V.J., Luo,D., Lee,Y.J.,
            Harrison,J.K., Oh,S.P. and Swanson,M.S.
  TITLE     Developmental expression of mouse muscleblind genes Mbnl1, Mbnl2
            and Mbnl3
  JOURNAL   Gene Expr Patterns 3 (4), 459-462 (2003)
   PUBMED   12915312
REFERENCE   10 (bases 1 to 8829)
  AUTHORS   Squillace,R.M., Chenault,D.M. and Wang,E.H.
  TITLE     Inhibition of muscle differentiation by the novel
            muscleblind-related protein CHCR
  JOURNAL   Dev Biol 250 (1), 218-230 (2002)
   PUBMED   12297108
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL671848.7, AK040522.1 and AL844490.4.
            
            On Jul 15, 2015 this sequence version replaced NM_134163.4.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC057157.1, AK088971.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164133, SAMN01164142
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-158               AL671848.7         34922-35079         c
            159-217             AK040522.1         1-59
            218-464             AL844490.4         100119-100365       c
            465-669             AK040522.1         60-264
            670-4277            AK040522.1         266-3873
            4278-4278           AL844490.4         53746-53746         c
            4279-5054           AK040522.1         3875-4650
            5055-8829           AL844490.4         49195-52969         c
FEATURES             Location/Qualifiers
     source          1..8829
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 28.03 cM"
     gene            1..8829
                     /gene="Mbnl3"
                     /gene_synonym="A530038J18Rik; CHCR; E430034C16Rik; MBLX;
                     MBLX39; MBXL"
                     /note="muscleblind like splicing factor 3"
                     /db_xref="GeneID:171170"
                     /db_xref="MGI:MGI:2444912"
     exon            1..217
                     /gene="Mbnl3"
                     /gene_synonym="A530038J18Rik; CHCR; E430034C16Rik; MBLX;
                     MBLX39; MBXL"
                     /inference="alignment:Splign:2.1.0"
     exon            218..464
                     /gene="Mbnl3"
                     /gene_synonym="A530038J18Rik; CHCR; E430034C16Rik; MBLX;
                     MBLX39; MBXL"
                     /inference="alignment:Splign:2.1.0"
     CDS             288..1316
                     /gene="Mbnl3"
                     /gene_synonym="A530038J18Rik; CHCR; E430034C16Rik; MBLX;
                     MBLX39; MBXL"
                     /note="isoform 1 is encoded by transcript variant 1;
                     muscleblind-like protein 3; cys3His CCG1-required protein;
                     muscleblind-like X-linked protein; muscleblind-like 3"
                     /codon_start=1
                     /product="muscleblind-like protein 3 isoform 1"
                     /protein_id="NP_598924.1"
                     /db_xref="CCDS:CCDS40969.1"
                     /db_xref="GeneID:171170"
                     /db_xref="MGI:MGI:2444912"
                     /translation="MTPVNVALIRDTKWLTLEVCREFQRGTCSRADAECRFAHPPRVC
                     HVENGRVVACFDSLKGRCTRENCKYLHPPPHLKSQLEVNGRNNLIQQKTAAAMFAQHM
                     QLMLQNAQMSSLASFPMNPSLAANPAMAFNPYMTHPGMGLVPAELLPNGPVLISGNPP
                     LALPGVPGPKPIRTDRLEVCREFQRGNCTRGESECRYAHPTDVSMIEVTDNSVTICMD
                     YIKGRCSREKCKYFHPPPHLQAKLRAAHHQMNHSAANAMALPHGALQLIPKRSALDKA
                     NGATPVFNPSVFHCQQALANMQIPQQAFIPTVPMMHGATPSTVSTATPPASNVPYVPT
                     TTGNQLKY"
     exon            465..629
                     /gene="Mbnl3"
                     /gene_synonym="A530038J18Rik; CHCR; E430034C16Rik; MBLX;
                     MBLX39; MBXL"
                     /inference="alignment:Splign:2.1.0"
     exon            630..821
                     /gene="Mbnl3"
                     /gene_synonym="A530038J18Rik; CHCR; E430034C16Rik; MBLX;
                     MBLX39; MBXL"
                     /inference="alignment:Splign:2.1.0"
     exon            822..1058
                     /gene="Mbnl3"
                     /gene_synonym="A530038J18Rik; CHCR; E430034C16Rik; MBLX;
                     MBLX39; MBXL"
                     /inference="alignment:Splign:2.1.0"
     exon            1059..1209
                     /gene="Mbnl3"
                     /gene_synonym="A530038J18Rik; CHCR; E430034C16Rik; MBLX;
                     MBLX39; MBXL"
                     /inference="alignment:Splign:2.1.0"
     exon            1210..1304
                     /gene="Mbnl3"
                     /gene_synonym="A530038J18Rik; CHCR; E430034C16Rik; MBLX;
                     MBLX39; MBXL"
                     /inference="alignment:Splign:2.1.0"
     exon            1305..8829
                     /gene="Mbnl3"
                     /gene_synonym="A530038J18Rik; CHCR; E430034C16Rik; MBLX;
                     MBLX39; MBXL"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1854..1859
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mbnl3"
                     /gene_synonym="A530038J18Rik; CHCR; E430034C16Rik; MBLX;
                     MBLX39; MBXL"
                     /note="hexamer: ATTAAA"
     polyA_site      1873
                     /gene="Mbnl3"
                     /gene_synonym="A530038J18Rik; CHCR; E430034C16Rik; MBLX;
                     MBLX39; MBXL"
     regulatory      8804..8809
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mbnl3"
                     /gene_synonym="A530038J18Rik; CHCR; E430034C16Rik; MBLX;
                     MBLX39; MBXL"
                     /note="hexamer: AATAAA"
     polyA_site      8822
                     /gene="Mbnl3"
                     /gene_synonym="A530038J18Rik; CHCR; E430034C16Rik; MBLX;
                     MBLX39; MBXL"
                     /note="major polyA site"
ORIGIN      
        1 tttcacgacg caagtgcgtc ctacaggaag aaagtgcccc cagtcggagc gcgagcagga
       61 gcgcgacttt ttggcgctct ttgcgagcga gccgcaagga ggcggaagac ggtcccgggc
      121 cggggcgcgg gaatcggggc agcgagcgcc gcacggggga gttcctgcgc gtggcgtcct
      181 cgcagcgaga cgccgctgga gtcgctcact cggagagatt ccttgaacca tctgcagtca
      241 tattattctc tgaagagggt gcacttgatt gccaatttgc tctcagtatg acacctgtca
      301 atgtagctct aatccgtgat accaagtggc tgactttaga agtctgtaga gaatttcaga
      361 gaggaacttg ctctcgagct gatgcagagt gcaggtttgc ccatccgcca agagtttgcc
      421 atgtggaaaa tggccgagtg gtggcctgtt ttgattcact aaagggtcgg tgcactcgtg
      481 agaactgcaa gtacctccac cctccaccgc acttaaagtc gcagctagaa gttaatggga
      541 gaaacaatct gattcaacag aagactgccg cagccatgtt cgcccagcac atgcaactca
      601 tgctgcagaa cgctcagatg tcatctcttg cgtcttttcc tatgaatcca tcacttgcag
      661 ctaatcctgc catggctttc aatccttaca tgactcatcc tggcatgggc ctggttcctg
      721 ctgagctttt accaaatggt ccggttctga tttctggaaa ccctcctctt gcactgccag
      781 gagttcctgg tccaaagcca attcgtacag atagactgga ggtttgccgt gaatttcagc
      841 gtggaaattg tacccgtggg gagagcgagt gccgctatgc tcaccctacg gatgtttcca
      901 tgattgaagt cactgataat tctgtgacaa tctgcatgga ttacattaaa ggccgatgct
      961 cccgggagaa atgcaagtac tttcatcctc ctccccactt gcaggccaaa ctcagggcag
     1021 ctcatcacca gatgaaccat tctgctgcca atgcaatggc cctgccgcat ggtgcacttc
     1081 aactgatacc aaagaggtca gcccttgaca aggccaatgg tgccactcca gtctttaacc
     1141 ccagtgtttt ccactgccaa caggctctgg ctaacatgca gattcctcag caggctttta
     1201 tcccaacagt gcccatgatg cacggtgcta caccttccac tgtgtctaca gcaacaccac
     1261 ctgccagcaa cgttccctac gttccaacaa ctacaggcaa ccagttgaaa tattgagcag
     1321 cagagttaca gagtatcaga atctctcaac aagaaactcc gtgtggcctt tctatatgta
     1381 ttctcgtatg tcttcttgta ccaacacgac aataagcatg gtgcagtcaa tatactaaag
     1441 cgcatatacc tgttgacaaa ttcaaatttt aaaaatctgt ggagatgtta aagcaaatag
     1501 aaaattaacc agtatgtgtt accttatacg gattcattgt atatgaatta gcatacaata
     1561 tacaaccata caggtttgtc atgtatatga attatcagat ccatattaca tgaattttcc
     1621 atatgatatg aattaccata ttgaatataa ctgtaaaatg ttgtgactgc tttccagtaa
     1681 tggtttataa taaatgaact tccacagtgt actgtaggct tactgtatac tcttggtgga
     1741 taaattctgt tttggaagtg ttaccttact gttttgttta caagatagtc tataggattg
     1801 atgtagaatg taactgatat ttcccacacc attttcctcc attggtatat tgtattaaat
     1861 tgggttctgc ttagctcttt catgctatag tgttttcttg tttatacgtg atatttgatt
     1921 tcaattaaag catcataagt ggtgaacaga actatatgtg actgaaaaat gtgacaggtt
     1981 catggtaata tgccctcttt aaaacatttc tgcaagtttc cggaggcctc acttctgagt
     2041 gtgcacaaaa tctcttcata tatagaattt tacctgtaga tctgaccttg catagtcaat
     2101 aatatactaa atttttaaaa gagaaaaaaa cttccctaca tgtgatagga aagttcaaat
     2161 gttaacctca aaccattcct cttaaataat ttgagaatca agtgttcaca ttccaataaa
     2221 tttcttagca tgtataaaaa ttacggagag tagccattac atttattgtg ttacaggaat
     2281 cctatctctc agcttgagtg tctaaatttg agccatttgt catcttcagc tgagaaactg
     2341 gtactaacta ctttaaaggt atactaatca caggctgaaa atcaagcaga gagatgtggg
     2401 cgtggagaca gtttttatgt actggaagaa agtgtgtaaa ccctttgcat tgtaaccttt
     2461 tgcacaaatg ctgttttcca aatgcaaatg gctcgtgctc ttttgactat tctttgaata
     2521 ataagtaaga tgcagtctgg caaaagtcag gccaggtgaa agaaaattgt ttccaaatga
     2581 ggccttgcct ccccaaatgg accatctttt ctattgatca cagaaggagg ctgagtacag
     2641 gtttagagaa atggcaggaa tgggggcagg gagagattta aaatgactgg gaatgtgcaa
     2701 aagaactaga aaaggtttcc gaagttgtct ttcggtttag tttaatttag ttgagtttcc
     2761 agtttttgta aaggcagcag tgaattagca agcatttgtg ctactgtatg gacaagggtt
     2821 tctctgccaa aactttaaca tcagagggtt ggctgtgggg gggggagatg atgatttgtt
     2881 cagttttgtc tcagaaccaa acctattttt gtcacatctg aacttacttg cctttgtgtg
     2941 tgtttcaaaa ttagttttaa catcctttgg ttaatagaga atagcaatag ccccatggag
     3001 gtgtgatatg aattcttctt aactaatact taggaaataa gctacaaata tggtaatcca
     3061 tctatttctg tgacatatag tgtacttctt ctacttagca ctactattgt tataagaggg
     3121 aggaaatgta ttttccaaaa gcctaagtaa attgaatatt ttatactcag tatatattct
     3181 cccaccagaa agcataaaat caaatttttg tacatataac agttgttttt cttcatgaaa
     3241 atcgggagga aagagagact gtccaggata tcataagaca ggtagttgga ttgatttgcc
     3301 aaacagtgac attggcaaag actttattgc cttttctacg gttggtaaaa cagagagcca
     3361 gactgtgtga cttgcctcag gctggctgcc tagccattgt gggaaccaat tgctctccct
     3421 ctttacatct ttctttggaa catttgagac tcctatgcaa agcagatcag atcggctcag
     3481 cattttaaaa aagcaaaact acctctggtg gatggtatct cattgatctt aattatccag
     3541 gtgaatcctg gttaccagtg attgctaaat actcttgttt ttatattgga cctccgccct
     3601 ttgttgacta ttgcctggag ctaagagatt gagagttgtc tgtcctttta cctgtgggct
     3661 ctttgaacca ctatatttct gttttctaac atcgcaattc caggaagaat ctacctgagc
     3721 tagtctagat gtagttatta atggatatgg aaatgttttg tgcaaaataa actttttgta
     3781 gtttgacact ttggtgcaac atactatctg gtttaacttc ttaaaatttt gatcaagata
     3841 tatgtagatg ataaacttag agtagagttg ttctcttgtt gctctaagca ctggaagata
     3901 ttaatgttga cttatattta ggaggagatt cagtggggaa cattcagggt agttgtcttt
     3961 ttggtgcgat gagtttaata taagtgttag cattttaaaa gttgcaatgt acatgaagct
     4021 taagaaagca agctcaaaac tcgaacattt tgatcaaatt tgatggagtt ttgagggaaa
     4081 tgaaacttta agctggcact ctagttgtgc agtgactaat gatcttattg aagaaaagac
     4141 aagtcatttg actataaatt gagttaacca gaccagtcac aaccaatcag tgactctaaa
     4201 tgaaaattta cccaagtatt tgtatataaa ccaaattcta atcagatgtg atttctagtt
     4261 agcatttttt agtttttgtg ttttgccatg gcctctattt ttatttctcc aaaattattg
     4321 gctttgtcca tctcagcctt ttgccaaaat ttgcaagaac actgaaactt ggataaaatg
     4381 tgtcaaacct acaaataagc aatctaaatt tgtcatttaa gaagagctta gtttcagttt
     4441 ttgcaaaaaa ccatgagacc gtaatgagta ggaactagaa tgaaattgaa tggattcgta
     4501 caactgctat ttaaatacag tgtttacttt tgaaattgga gcatgaatcc acacctagct
     4561 attgcttttc atttgacttt tctagataaa ttttcagttt tcatctattc atgaaagcag
     4621 tctgcttgct attccatcag tcttgctctg ccgttcatct ctgagcatcc taaaacactg
     4681 tgatcttgcc ataagtgttg tcctatgcca ctcgactgtg tccactcatg ggaccctcaa
     4741 ctctcctgct ctcaactctc agcaggaacc aaattaactt agtattttgt gcttgggttc
     4801 actttaacag cataaggagt gagacagtgc tgtttggagg acgaacagca gctacagtac
     4861 attgtaggaa gggaaagagg cagctgaggc gctcatgagc tcctcggaat gccaggtgat
     4921 tctcttcctt gtctttggtg agtgttggta aggaggcccc tagacaaaat gcagccaagg
     4981 ttgtcgaaga tctggcggtc tgtgggatag gctgtggcat gcagaaggct tactaacaaa
     5041 gttctcgctc cacctttaaa aaaaaaaaag aaagctcttc tacatttcac tgaaatggaa
     5101 atgagtaaaa ttggggggag gggtgtctga ttcggtttga ttcatttgat ggatttgatt
     5161 ccaagttttg atttgtagat ttaataagat agtggcctaa ttttaccgga gtctgttaga
     5221 gatagtagaa taaaatagca aataagagag tttagctttt ttttttgaaa gtttagtaga
     5281 tagtctaatc aaactataaa ctgtaaatgt gattataaat acaggctctg agtaccaagt
     5341 tactaattgg tgccatgttt tcgtttttct tattgttagt ttttaaagtt ttaattgtac
     5401 tacattttta tatctaagta tccaatgagt ttaattttga aggagagttg gagaaggttt
     5461 aaggttttac cacttctatt cagaccatct ctgtaggctc taaactgaga ccatagcgta
     5521 attcagcata gatacagtcc agaactaccc tctacaatcc acagttcaag aacaaattta
     5581 gcgttgtaca caaatgatag atgtcagcta aatatattta gttgttgcct tggcaacaaa
     5641 actacaacat ggctaccttt agacatttat gcatgtaaaa cttttatgtg taagctatat
     5701 gtggttcatg acagtgcaaa catattgaag atacagctca aaactcagaa aactgatgat
     5761 gtttttgaag ccctgtgttc catatatgaa agctgaattt gtgtcctcat gttaacattt
     5821 gattcgaaaa agaagtttat aacacatgga ttctagaatt gggctttatc gtttaaagaa
     5881 ttggttgggt tgatagggtt attctacagt agaacaagct cgacattgat attgcctggc
     5941 ctttttttca caactttatt caaaactacc tattcgtgta gtatctgtag ttataaaaag
     6001 attatatttt ctggctttat tcacaaaaac tatatgtgag gattaaagca taagtaaaca
     6061 tgttgagatt aacccatggt tgtgaagcca cacataaaga tactatagaa gagcccctga
     6121 acagtgttta agagacatat gctgcagttc cccgactgtc ccagttaggg tgcgaatgtg
     6181 tgagacccat cttttttttt tttttttttt ttttttgcac ttatgtacat agtccatgaa
     6241 agcaatcctt ggagcttttg acaatgtaag aagtctgtgg taatagagga gcattagtga
     6301 gagtgctgtt tgaggctcta agaattagtg gaagcatagt gtagcagtac tgttgagggg
     6361 gcttgctagc tggctacagc ccaccagaag ctcagactgc taacacatgc cagatccccc
     6421 taacagcact gagtgagaat acaaagcact tcttttcgta aggctactag caaaagttat
     6481 ttgctttttg aattaactcc cactgtaaaa acacacacac acgcacacac acacacacac
     6541 acacacacac acacacacac acacgaatgc ttatactaca taatggataa ggttcccagt
     6601 agagattttc ttttttccaa ttatagaaag aagagaaact actctgtaca ttacaagcta
     6661 gttagttact ctcaaatcta attaaaacag atctcatcct tcgtagttta aaattatatc
     6721 agttaatgtg gatttaagtg aaaaattgtt aatgttttaa ctaaacagaa gtgaagcagc
     6781 ccaaatctta tagaagatgg accctggaaa atgatgtcaa tttaacctac tctgccagtt
     6841 ctcactccac atttgcagat agccaaggag ccttcttgtt gttctccaag gcactgaggc
     6901 ttagcaaagt tggaagtttg aaaggttaag ggacagatca tctctggcac tttgaatcct
     6961 tcccatctta agacagatgt ctttcacact aaggacccca tcctaggcta agggtagttg
     7021 tgaaatgttg cttttcatac actgctaact ctcttggagg catataacta gatctgcacc
     7081 cataggtcat tagtacagca cttgcctgga tgaacaaggc cctgggttcc atccccagga
     7141 ctgcaaaagg aaaaaagggg gaagaaagag agagaaagat ggaaaacaga ccaaagctac
     7201 aaacaaccca agccttacat gtatcccgta gctcagggcc agttggctaa aaattattta
     7261 attttccctt cagcttctga tcactaagtc agtttgttgt atggctatac aacaaacgcc
     7321 ctgacaatct gagcagctgt ttttagccaa tagaagatgg aagcatatat tcattttata
     7381 gttaagaatg cccacttcag ccttactacc cccataattt cactacttca ccagcatcct
     7441 tacgtggacg tttccttgtg aatctctaag tcataagaat gcatcttcat aaggacaata
     7501 gaaagatgaa attttgtgta tggtgctgag aatacagccc agggctttgt gtgctatgca
     7561 aatgctctaa caccctggtt agccagtgat aagattttaa gtccagagct atcaaccata
     7621 aattagtagg gatgagcctt gaagcatcac aaaagatagc caatgaattt ataacatgta
     7681 catgcccacc accacttggt cccatgctga agcttaaaca tagtgactgt atttcaatca
     7741 ttcaaacaaa ggagaggatt aagtataacg agtgcatgtg attcaagcta aaagataaat
     7801 tgggatttaa gtttgacaaa cttagcattt ctagcccttc tgccttgcct ataagtgaat
     7861 tacccactgg aattgaaaat ctagattatc ccaaagaaaa tgtatgtgta tagagaaccc
     7921 ttcctcaatc ataaaagatg aaaagtgctt tggtctgaaa taagttgcca ctccgtatag
     7981 atacttcaag aatcctcact agccctcttt tacattgtgt tactttaaaa aaaaatacct
     8041 ctgtagcaag acctagaaga attaagtgag ctttttctcc cacacatgta caaccttaag
     8101 actctgccat agaactgcat ggttgcaaag ctttatttct gtatacagat gctatctgtt
     8161 aatgatggaa accaaattgt tgtcttgccg tgtcttttgt gtctagcagt tgagtggatg
     8221 atatgaccat catttcatta gatgctgggg ataacctcaa aataagtttc ttattattat
     8281 cataactgtt agttcggtta caaaatgagc catttgctcc caaattacac taattaaaat
     8341 gaggtccatt ttttagaaaa tgaggtctca ctcactatgt tgtgtaaact agtccaaatt
     8401 ccatggcctt gaatgatttg attattcctc ggtgtgactt ctttcgcttg accaggatga
     8461 gctaggttat tcctttgtgt aattttaaag aataacttat agctccagct aacaatgatc
     8521 tggactgtag ggagaggagg catttgtctt gggcagggga tggcaatata agaatttctt
     8581 tgccctatgc cacaattaaa aactgaaata agaaccaaaa tattttacaa gtaaaaactg
     8641 ttcacataat attttgttcc caaatgtggt aattcattcc ctcaactgca gatgtttgga
     8701 ctttttcaag ttatagtgtt gtatgcctgt ttgtgtttag aagtgttcat tatatagctc
     8761 attttagtat gctacttttt atgtttcctt tttttattct ttcaataaag tttgcaaatt
     8821 ccttggtta
//
