LOCUS       NM_177718               3432 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus Mab-21 domain containing 2 (Mb21d2), transcript
            variant 1, mRNA.
ACCESSION   NM_177718
VERSION     NM_177718.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3432)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3432)
  AUTHORS   Ahmed,S.M., Theriault,B.L., Uppalapati,M., Chiu,C.W., Gallie,B.L.,
            Sidhu,S.S. and Angers,S.
  TITLE     KIF14 negatively regulates Rap1a-Radil signaling during breast
            cancer progression
  JOURNAL   J Cell Biol 199 (6), 951-967 (2012)
   PUBMED   23209302
REFERENCE   3  (bases 1 to 3432)
  AUTHORS   Munton,R.P., Tweedie-Cullen,R., Livingstone-Zatchej,M.,
            Weinandy,F., Waidelich,M., Longo,D., Gehrig,P., Potthast,F.,
            Rutishauser,D., Gerrits,B., Panse,C., Schlapbach,R. and Mansuy,I.M.
  TITLE     Qualitative and quantitative analyses of protein phosphorylation in
            naive and stimulated mouse synaptosomal preparations
  JOURNAL   Mol Cell Proteomics 6 (2), 283-293 (2007)
   PUBMED   17114649
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC154807.2.
            
            On May 5, 2022 this sequence version replaced NM_177718.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC085092.1, SRR7345562.4186094.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-598               AC154807.2         169843-170440       c
            599-3432            AC154807.2         66566-69399         c
FEATURES             Location/Qualifiers
     source          1..3432
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 19.71 cM"
     gene            1..3432
                     /gene="Mb21d2"
                     /gene_synonym="1600021P15Rik; A430031N04"
                     /note="Mab-21 domain containing 2"
                     /db_xref="GeneID:239796"
                     /db_xref="MGI:MGI:1917028"
     exon            1..598
                     /gene="Mb21d2"
                     /gene_synonym="1600021P15Rik; A430031N04"
                     /inference="alignment:Splign:2.1.0"
     CDS             388..1863
                     /gene="Mb21d2"
                     /gene_synonym="1600021P15Rik; A430031N04"
                     /note="isoform 1 is encoded by transcript variant 1;
                     protein MB21D2; mab-21 domain-containing protein 2;
                     nucleotidyltransferase MB21D2"
                     /codon_start=1
                     /product="nucleotidyltransferase MB21D2 isoform 1"
                     /protein_id="NP_808386.2"
                     /db_xref="CCDS:CCDS28093.1"
                     /db_xref="GeneID:239796"
                     /db_xref="MGI:MGI:1917028"
                     /translation="MKMAAPTASKAASLGCNNKPAFPELDFRSGARVEELNKLIQEFT
                     RHDQREYDDQRALEIHTAKDFIFSMLGMVQKLDQKLPVANEYLLLSGGVREGVVDLDL
                     DELNVYARGTDYDMDFTLLVPALKLHDRNQPVTLDMRHSALCHSWLSLRLFDEGTISK
                     WKGCCTIADHINGATNYFFSPTKVADWFYDSISIVLSEIQKKPQRGMPKVEKVEKNGT
                     IISIILGVGSSRMLYDIVPVVSFKGWPAVAQSWLMENHFWDGKITEEEVISGFYLVPA
                     CSYKGKKDNEWRLSFARSEVQLKKCISGSLMQAYQACKAIIIKLLSRPKAISPYHLRS
                     MMLWACDRLPASYLAQEDYAAHFLLGLIDDLQHCLVNKMCPNYFIPQCNMLEHLSEET
                     VMLHARKLSSVRSDPAEHLRTAIEHVKAANRLTLKLQRRGSTTSIPSPQSDGGDPNQP
                     DDRLAKKLQQLVTENPGKSISVFINPDDVTRPHFRIDDKFF"
     exon            599..3432
                     /gene="Mb21d2"
                     /gene_synonym="1600021P15Rik; A430031N04"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3369..3374
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mb21d2"
                     /gene_synonym="1600021P15Rik; A430031N04"
                     /note="hexamer: TATAAA"
     regulatory      3404..3409
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mb21d2"
                     /gene_synonym="1600021P15Rik; A430031N04"
                     /note="hexamer: AATAAA"
     polyA_site      3410
                     /gene="Mb21d2"
                     /gene_synonym="1600021P15Rik; A430031N04"
     polyA_site      3432
                     /gene="Mb21d2"
                     /gene_synonym="1600021P15Rik; A430031N04"
                     /note="major polyA site"
ORIGIN      
        1 gtaacaccgg agccggcagc ttgttgattt cagcgctggt gaatttcaca ttgtttccac
       61 ttcactttcc ttgcccccgg ggaggctcga gtccactccc ggacgccgcc accgatcccg
      121 gcaggactcg aggagggcag gggcccgcag cggcgcagcg ggcgggggcg ggaggaccgg
      181 gggccggggc cacacgcgca cctcgccgca gtcgggctcc tcccgcgaag gagcgcggcc
      241 gccccgagcg cagcgcggcg cggggcccgt ccagaagcca gcccgcccac gggccgggct
      301 gcccagccgc gccgggaggc cggggcgggg tggggggcgg gggtgggtgc cgcggccgcc
      361 gcggagccgc cgctcggcgc gttttgcatg aagatggcgg ctcccaccgc cagcaaggca
      421 gcctccctgg gctgcaacaa caagcctgcc ttcccggagc tggatttcag gtctggagct
      481 cgggtggagg aactgaacaa actcatccag gaattcacca ggcacgacca gcgggaatac
      541 gacgaccaga gagcgctgga gatccacact gccaaggatt tcatcttttc catgctggga
      601 atggtgcaaa agctagatca aaaacttccc gtggccaacg agtatctgtt gctctccgga
      661 ggagtccggg aaggtgtggt ggacctggac ctagatgagt taaacgtcta tgcccggggc
      721 actgactacg atatggactt tacccttctg gtgcccgccc ttaagctgca tgaccgtaac
      781 cagcctgtga cgctcgatat gcgccactca gccctgtgcc actcctggct gagcctcagg
      841 ctctttgatg aggggacaat cagtaaatgg aaaggttgct gcacaatcgc cgatcacatc
      901 aacggtgcca ccaactactt cttctccccc accaaagtgg ctgactggtt ctatgactcc
      961 atcagcatcg tcctctcgga gatacagaag aaaccccaga gagggatgcc gaaggtggag
     1021 aaggtagaga agaacggtac catcatctcc atcattctgg gcgtggggag cagccgcatg
     1081 ttgtacgaca tcgtccccgt ggtgtccttc aaaggctggc ccgcggtggc tcagagctgg
     1141 ctcatggaga accacttttg ggatgggaag atcaccgaag aagaggtcat cagtggcttc
     1201 tacctggtgc cagcttgctc ctacaaaggc aagaaggaca atgagtggcg actgtccttc
     1261 gccaggagcg aggtacaact gaagaagtgc atttcaggca gtctaatgca ggcctaccaa
     1321 gcctgcaaag ccatcatcat caaactcctg tcgaggccca aggccatcag cccttatcac
     1381 ctgcggagca tgatgctctg ggcctgtgat cgactccctg ccagctactt ggctcaagaa
     1441 gactatgcag cccacttttt gctgggcctc attgacgacc tgcagcactg cctggtcaac
     1501 aagatgtgcc ctaattattt catccctcag tgcaacatgc tggagcatct gtcagaggag
     1561 acagtcatgc tccacgcccg gaagctctcc tcggttcgct ccgatcccgc agagcacctg
     1621 cgcaccgcca ttgagcacgt gaaggcagcc aatcggctga cgctgaagct ccagcgtcgg
     1681 ggcagcacca ccagcatccc ctccccacag tcggatggcg gggaccccaa tcagcctgat
     1741 gaccgtctgg caaaaaaact gcagcagcta gtgactgaga atccagggaa gtccatctcg
     1801 gtctttatta accccgatga cgtcacgagg ccccatttca gaatcgatga taaatttttc
     1861 tgagtgtttt gttgactttt ttccccctat ctttcttggt tctaaaattt acgtaccgtg
     1921 tagtgtgatt tgtgactgtc gttctgtttt ttacatatcc agctaacatt ggacttggta
     1981 agaacacagg ttctgcagga tggtgcgggc tctgaaacag tattattact atttcatatt
     2041 ctgcctgatt ttgctgtttg ttttctagtt attgtggatt tttatttttc ttggttttca
     2101 ttgttttaaa ggagaacttg agccatagac gacactgccc acgaatcctc ttgcttgctt
     2161 tctgtcccac acccagtgta gatttgttgg tgggtttggg ggaacacatc tcctcctggc
     2221 atatttgaac acattctctt cctcttcggc tgatgttctg tctttgacct cgttcttctc
     2281 ccgagttttc actgagagtc ctaagaacct gcggccctgt gcatgctggc tgcgtttatt
     2341 tctttgcacc agcagtcaga acagtttccc ctttctacga gacatggaaa cttcaagaga
     2401 gagagagaga gtgatgtcta ttgtgtttct gagcaacctc attgaatgta attgttctcg
     2461 aatcagcaaa cattggatgg tttggaggga gggtttgata gctttccaaa cagaattaag
     2521 gtttccaaat gttagtttta gtgtttgtaa ttatttgaag ccttatttaa atcctattaa
     2581 ggagcacacc attctaattg ttatttgcac taatgaagtc tttgccattg tcataagctt
     2641 cgatgtgtgt tttagcgtcc attgacatct ctctggaaaa ggctgttgtc gcctctcgtt
     2701 tagtccagtt ctcccggtca gtaggatgag tctctacatt ttgtctagtt ctcctttcat
     2761 tgtgggtccc gttttgccct ctttgatagc tctggtttct gccttactga ggggagttct
     2821 taaagcttta tacctattca ctgaccatct gaagctgggg gagataggag ataatacttg
     2881 atcaagtggg tgtctttgta tttatttctt tgagggaggg gttctagaga tcttctcttc
     2941 ccccttttct tttataaagt ccctttacgt ctcctgagat cttgagggaa actgacaggc
     3001 agaattgttc ccagattgaa gataaccatg cctgttcaaa gcaggtgtca ctgtagagca
     3061 ggaaccagga aatacctagg tagctctgtt ggaagaaggg agtcctatta tctgacagga
     3121 actatttgcc agatttgggt gcttcagggt gtgttggccc ctgtttgggt gtgaactcaa
     3181 ggcaaaccgt ggtgcttgag tcgtggacgg ccctgctgac atagatgaca ccgatgatgt
     3241 ctgctgatgg aagagtcaag caagcaacag tggctgtttt ggtcttgagt gtccagactc
     3301 atataggttg gattttggcc agttggaatc aggctcttgg agttttgcat gggaattaat
     3361 gtaatgctta taaatcactc aacaatctca agtcaaacac aaaaataaaa gagaaacata
     3421 ctggccttgg aa
//
