LOCUS       NM_001372522            2715 bp    mRNA    linear   ROD 01-MAY-2024
DEFINITION  Mus musculus MYC-associated zinc finger protein (purine-binding
            transcription factor) (Maz), transcript variant 3, mRNA.
ACCESSION   NM_001372522 XM_006507402
VERSION     NM_001372522.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2715)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2715)
  AUTHORS   Gu,Y., Zhou,Y., Ju,S., Liu,X., Zhang,Z., Guo,J., Gao,J., Zang,J.,
            Sun,H., Chen,Q., Wang,J., Xu,J., Xu,Y., Chen,Y., Guo,Y., Dai,J.,
            Ma,H., Wang,C., Jin,G., Li,C., Xia,Y., Shen,H., Yang,Y., Guo,X. and
            Hu,Z.
  TITLE     Multi-omics profiling visualizes dynamics of cardiac development
            and functions
  JOURNAL   Cell Rep 41 (13), 111891 (2022)
   PUBMED   36577384
REFERENCE   3  (bases 1 to 2715)
  AUTHORS   Cao,X., Yan,Y., Luo,X., Yang,X., Cui,H., Yang,Y. and Li,H.
  TITLE     Analyses of the circadian clock genes expression in whole embryos
            and maternal major tissues of mice
  JOURNAL   J Mol Histol 53 (2), 473-482 (2022)
   PUBMED   35149920
REFERENCE   4  (bases 1 to 2715)
  AUTHORS   Ortabozkoyun,H., Huang,P.Y., Cho,H., Narendra,V., LeRoy,G.,
            Gonzalez-Buendia,E., Skok,J.A., Tsirigos,A., Mazzoni,E.O. and
            Reinberg,D.
  TITLE     CRISPR and biochemical screens identify MAZ as a cofactor in
            CTCF-mediated insulation at Hox clusters
  JOURNAL   Nat Genet 54 (2), 202-212 (2022)
   PUBMED   35145304
  REMARK    GeneRIF: CRISPR and biochemical screens identify MAZ as a cofactor
            in CTCF-mediated insulation at Hox clusters.
REFERENCE   5  (bases 1 to 2715)
  AUTHORS   Medina-Martinez,O., Haller,M., Rosenfeld,J.A., O'Neill,M.A.,
            Lamb,D.J. and Jamrich,M.
  TITLE     The transcription factor Maz is essential for normal eye
            development
  JOURNAL   Dis Model Mech 13 (8) (2020)
   PUBMED   32571845
  REMARK    GeneRIF: The transcription factor Maz is essential for normal eye
            development.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2715)
  AUTHORS   Wu,C.X., Zhao,W.P., Kishi,H., Dokan,J., Jin,Z.X., Wei,X.C.,
            Yokoyama,K.K. and Muraguchi,A.
  TITLE     Activation of mouse RAG-2 promoter by Myc-associated zinc finger
            protein
  JOURNAL   Biochem Biophys Res Commun 317 (4), 1096-1102 (2004)
   PUBMED   15094381
REFERENCE   7  (bases 1 to 2715)
  AUTHORS   Ugai,H., Li,H.O., Komatsu,M., Tsutsui,H., Song,J., Shiga,T.,
            Fearon,E., Murata,T. and Yokoyama,K.K.
  TITLE     Interaction of Myc-associated zinc finger protein with DCC, the
            product of a tumor-suppressor gene, during the neural
            differentiation of P19 EC cells
  JOURNAL   Biochem Biophys Res Commun 286 (5), 1087-1097 (2001)
   PUBMED   11527412
REFERENCE   8  (bases 1 to 2715)
  AUTHORS   Xiong,J.W., Leahy,A., Lee,H.H. and Stuhlmann,H.
  TITLE     Vezf1: A Zn finger transcription factor restricted to endothelial
            cells and their precursors
  JOURNAL   Dev Biol 206 (2), 123-141 (1999)
   PUBMED   9986727
REFERENCE   9  (bases 1 to 2715)
  AUTHORS   Song,J., Murakami,H., Tsutsui,H., Ugai,H., Geltinger,C., Murata,T.,
            Matsumura,M., Itakura,K., Kanazawa,I., Sun,K. and Yokoyama,K.K.
  TITLE     Structural organization and expression of the mouse gene for Pur-1,
            a highly conserved homolog of the human MAZ gene
  JOURNAL   Eur J Biochem 259 (3), 676-683 (1999)
   PUBMED   10092852
REFERENCE   10 (bases 1 to 2715)
  AUTHORS   Kennedy,G.C. and Rutter,W.J.
  TITLE     Pur-1, a zinc-finger protein that binds to purine-rich sequences,
            transactivates an insulin promoter in heterologous cells
  JOURNAL   Proc Natl Acad Sci U S A 89 (23), 11498-11502 (1992)
   PUBMED   1454839
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122863.4.
            
            On Sep 3, 2019 this sequence version replaced XM_006507402.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.2376508.1,
                                           SRR7652917.226831.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-363               AC122863.4         166962-167324       c
            364-1214            AC122863.4         166038-166888       c
            1215-1278           AC122863.4         165610-165673       c
            1279-1450           AC122863.4         165178-165349       c
            1451-1680           AC122863.4         164211-164440       c
            1681-2715           AC122863.4         162868-163902       c
FEATURES             Location/Qualifiers
     source          1..2715
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 69.28 cM"
     gene            1..2715
                     /gene="Maz"
                     /gene_synonym="MAZI; Pur-1; PUR1; SAF-1; SAF-2"
                     /note="MYC-associated zinc finger protein (purine-binding
                     transcription factor)"
                     /db_xref="GeneID:17188"
                     /db_xref="MGI:MGI:1338823"
     exon            1..363
                     /gene="Maz"
                     /gene_synonym="MAZI; Pur-1; PUR1; SAF-1; SAF-2"
                     /inference="alignment:Splign:2.1.0"
     CDS             172..1653
                     /gene="Maz"
                     /gene_synonym="MAZI; Pur-1; PUR1; SAF-1; SAF-2"
                     /note="isoform 3 is encoded by transcript variant 3;
                     purine-binding transcription factor"
                     /codon_start=1
                     /product="myc-associated zinc finger protein isoform 3"
                     /protein_id="NP_001359451.1"
                     /db_xref="CCDS:CCDS90332.1"
                     /db_xref="GeneID:17188"
                     /db_xref="MGI:MGI:1338823"
                     /translation="MFPVFPCTLLAPPFPVLGLDSRGVGGLMNSFPPPQGHAQNPLQV
                     GAELQSRFFASQGCAQSPFQAAPAPPPTPQAPAAEPLQVDLLPVLAAAQESAAAAAAA
                     AAAAAAVVTAPPAPAAASTVDTAALKQPPAPPPPPPAVSAPAAEAAPPAAAATIAAAA
                     ATAVVAPTSTVAVAPVASVLEKKTKSKGPYICALCAKEFKNGYNLRRHEAIHTGAKAG
                     RVPSGAMKMPTMVPLSLLSVPQLSGASGGGGEAGAGGGTAAVAAGGVVTTTASGKRIR
                     KNHACEMCGKAFRDVYHLNRHKLSHSDEKPYQCPVCQQRFKRKDRMSYHVRSHDGAVH
                     KPYNCSHCGKSFSRPDHLNSHVRQVHSTERPFKCEKCEAAFATKDRLRAHTVRHEEKV
                     PCHVCGKMLSSAYISDHMKVHSQGPHHVCELCNKGFTTAAYLRIHAVKDHGLQAPRAD
                     RILCKLCSVHCKTPAQLAGHMQTHLGGAAPPIPGDAPQPQPTC"
     exon            364..1214
                     /gene="Maz"
                     /gene_synonym="MAZI; Pur-1; PUR1; SAF-1; SAF-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1215..1278
                     /gene="Maz"
                     /gene_synonym="MAZI; Pur-1; PUR1; SAF-1; SAF-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1279..1450
                     /gene="Maz"
                     /gene_synonym="MAZI; Pur-1; PUR1; SAF-1; SAF-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1451..1680
                     /gene="Maz"
                     /gene_synonym="MAZI; Pur-1; PUR1; SAF-1; SAF-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1681..2715
                     /gene="Maz"
                     /gene_synonym="MAZI; Pur-1; PUR1; SAF-1; SAF-2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2697..2702
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Maz"
                     /gene_synonym="MAZI; Pur-1; PUR1; SAF-1; SAF-2"
                     /note="hexamer: AATAAA"
     polyA_site      2715
                     /gene="Maz"
                     /gene_synonym="MAZI; Pur-1; PUR1; SAF-1; SAF-2"
                     /note="major polyA site"
ORIGIN      
        1 cttccctccc tcccgccggc cggggtgcgc gggcggcggg gcggccctcg ggccatgcgt
       61 tcggctcggc ccaacccggc cggccggggg cggcgccccg agcccgggcc ccgcgcggcc
      121 cgtgcccccg gctcccgctg agctccgggg gcccccactg tggccgaggc catgttcccc
      181 gtgttccctt gcacgctgct ggcccccccc ttccccgtgc tgggcctgga ctcccggggg
      241 gtgggcggcc tcatgaactc cttcccgcca cctcagggtc acgcccagaa ccccctgcag
      301 gtcggggctg agctccagtc ccgcttcttt gcctcccagg gctgcgccca gagtccattc
      361 caggccgcgc cggcgccccc acccacgccc caggccccgg cggccgagcc cctccaagtg
      421 gacttgctcc cggttctcgc cgccgcgcag gaatcagccg cggcggcggc ggctgctgcg
      481 gcggctgccg ctgcagtggt tactgcaccc ccggcccctg ccgccgcctc cacagtggac
      541 acagcggccc tgaagcagcc tccggcgcct cctccgccac cccctgccgt ctccgcacca
      601 gccgccgagg ccgcgccccc cgccgcggcc gccactatcg cagcagcggc tgccaccgct
      661 gtcgtcgccc caacctcgac ggtcgccgtg gccccagttg catctgtctt ggagaagaag
      721 acaaagagca aggggcccta catttgcgcc ctgtgcgcca aggagttcaa gaacggctac
      781 aacctccgaa ggcacgaagc catccacacg ggagccaagg ctggccgggt cccttcgggt
      841 gctatgaaga tgcccaccat ggtgcccctg agcctcttga gtgtccccca gctgagcggg
      901 gccagcgggg gtgggggaga agccggggct ggcggcggca cagccgcggt ggcggccggt
      961 ggcgttgtga ccacgactgc ctctgggaag cgcatccgga agaatcacgc ctgcgagatg
     1021 tgcggcaagg ccttccgcga cgtctaccac ctgaaccgac ataagctgtc gcattcggac
     1081 gagaagccct accagtgccc tgtgtgccag cagcgcttca agcgcaagga ccgcatgagt
     1141 taccacgtgc gctcacatga cggcgctgtg cacaagccct acaactgctc ccactgtggc
     1201 aagagcttct cccggccgga tcacctcaac agtcacgtca gacaagtgca ctcaacagag
     1261 cggcccttca aatgtgagaa atgtgaggca gcttttgcta cgaaggatcg cctccgagcg
     1321 cacacagtcc gacacgagga gaaggtgcca tgtcatgtct gtggcaagat gctgagctcg
     1381 gcttatattt ccgaccacat gaaggtgcac agccagggcc ctcaccatgt ctgtgagctc
     1441 tgcaacaaag gcttcaccac agcagcatac ctgcgcatcc acgcggtgaa ggaccatggg
     1501 ctccaggccc cgcgggctga ccgcatcctg tgtaagctgt gcagcgtgca ctgcaagacc
     1561 cctgcccagc tggccggcca catgcagacc catctggggg gggccgcccc tcctatcccg
     1621 ggagatgccc cccagccaca gcctacctgc tgagggggac ccctgcaccc accaggcaag
     1681 gtactggtga ggtttgtcca atggcggcag cggcagcagc agcggcggcg gcggcagcag
     1741 cagtggtggc agcccccccc acagctgtgg gctccctctc tggggcagag ggggtaccag
     1801 tgagctctca gccacttccc tcccagcctt ggtgagctcc aagttgatgg gggagagggg
     1861 agagtggagg aaagctcttc ttggtacagt ctcctcttcc caccaactcc tcacgactct
     1921 tcatcaacca aggagcctcc agacagagag gaggaagaag gaattcacta ggttttaaca
     1981 atgtttctcc tgctcctttc ttctccctat cagagctgac cctacaaaca cctgtcccct
     2041 gagttgtgtt gaagtcccct ggacaatgag caggggtggc agaggacagc agcagccact
     2101 gccctcacct ttaacccctt gccttgcctc ccagggattt gtgagccttt cctagaaggt
     2161 cctgtgctct cctccttctg tcccctcccc tactgtctgc tgccccttcc tggggagttg
     2221 gtgctttctt ttttgttgtt gttttttccc aggggtaggg aggagagagg aggggaaaga
     2281 agattctgtc ccagaggaga gaaaaggtgg tattgaggag gggcagaagc ggggaaggca
     2341 gagggatact tgagtaaggt tgggtggtta aaccccaagc atcctactgg agtgtctgtc
     2401 cagggagaag ccaaggggag catcagaagg agccactgga gccagaggca gaacaagaga
     2461 gatggaatct tagggggcca gggcaaagga ggggagccag ggacaagagg tgcttcctgg
     2521 gggtggggga atgcagccac agtgtctccc ccttccctct tccaccccag ctccagccct
     2581 ggtctttctt cctctttccc ataacagaag ctatggccct ggccatgtca tcgtgttcct
     2641 gtgtcccttg catgttcccc accctcccct ccctcctttt gcgcagaccc cattacaata
     2701 aattttaaat aaaaa
//
