LOCUS       NP_001359451             493 aa            linear   ROD 01-MAY-2024
DEFINITION  myc-associated zinc finger protein isoform 3 [Mus musculus].
ACCESSION   NP_001359451 XP_006507465
VERSION     NP_001359451.1
DBSOURCE    REFSEQ: accession NM_001372522.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 493)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (residues 1 to 493)
  AUTHORS   Gu,Y., Zhou,Y., Ju,S., Liu,X., Zhang,Z., Guo,J., Gao,J., Zang,J.,
            Sun,H., Chen,Q., Wang,J., Xu,J., Xu,Y., Chen,Y., Guo,Y., Dai,J.,
            Ma,H., Wang,C., Jin,G., Li,C., Xia,Y., Shen,H., Yang,Y., Guo,X. and
            Hu,Z.
  TITLE     Multi-omics profiling visualizes dynamics of cardiac development
            and functions
  JOURNAL   Cell Rep 41 (13), 111891 (2022)
   PUBMED   36577384
REFERENCE   3  (residues 1 to 493)
  AUTHORS   Cao,X., Yan,Y., Luo,X., Yang,X., Cui,H., Yang,Y. and Li,H.
  TITLE     Analyses of the circadian clock genes expression in whole embryos
            and maternal major tissues of mice
  JOURNAL   J Mol Histol 53 (2), 473-482 (2022)
   PUBMED   35149920
REFERENCE   4  (residues 1 to 493)
  AUTHORS   Ortabozkoyun,H., Huang,P.Y., Cho,H., Narendra,V., LeRoy,G.,
            Gonzalez-Buendia,E., Skok,J.A., Tsirigos,A., Mazzoni,E.O. and
            Reinberg,D.
  TITLE     CRISPR and biochemical screens identify MAZ as a cofactor in
            CTCF-mediated insulation at Hox clusters
  JOURNAL   Nat Genet 54 (2), 202-212 (2022)
   PUBMED   35145304
  REMARK    GeneRIF: CRISPR and biochemical screens identify MAZ as a cofactor
            in CTCF-mediated insulation at Hox clusters.
REFERENCE   5  (residues 1 to 493)
  AUTHORS   Medina-Martinez,O., Haller,M., Rosenfeld,J.A., O'Neill,M.A.,
            Lamb,D.J. and Jamrich,M.
  TITLE     The transcription factor Maz is essential for normal eye
            development
  JOURNAL   Dis Model Mech 13 (8) (2020)
   PUBMED   32571845
  REMARK    GeneRIF: The transcription factor Maz is essential for normal eye
            development.
            Publication Status: Online-Only
REFERENCE   6  (residues 1 to 493)
  AUTHORS   Wu,C.X., Zhao,W.P., Kishi,H., Dokan,J., Jin,Z.X., Wei,X.C.,
            Yokoyama,K.K. and Muraguchi,A.
  TITLE     Activation of mouse RAG-2 promoter by Myc-associated zinc finger
            protein
  JOURNAL   Biochem Biophys Res Commun 317 (4), 1096-1102 (2004)
   PUBMED   15094381
REFERENCE   7  (residues 1 to 493)
  AUTHORS   Ugai,H., Li,H.O., Komatsu,M., Tsutsui,H., Song,J., Shiga,T.,
            Fearon,E., Murata,T. and Yokoyama,K.K.
  TITLE     Interaction of Myc-associated zinc finger protein with DCC, the
            product of a tumor-suppressor gene, during the neural
            differentiation of P19 EC cells
  JOURNAL   Biochem Biophys Res Commun 286 (5), 1087-1097 (2001)
   PUBMED   11527412
REFERENCE   8  (residues 1 to 493)
  AUTHORS   Xiong,J.W., Leahy,A., Lee,H.H. and Stuhlmann,H.
  TITLE     Vezf1: A Zn finger transcription factor restricted to endothelial
            cells and their precursors
  JOURNAL   Dev Biol 206 (2), 123-141 (1999)
   PUBMED   9986727
REFERENCE   9  (residues 1 to 493)
  AUTHORS   Song,J., Murakami,H., Tsutsui,H., Ugai,H., Geltinger,C., Murata,T.,
            Matsumura,M., Itakura,K., Kanazawa,I., Sun,K. and Yokoyama,K.K.
  TITLE     Structural organization and expression of the mouse gene for Pur-1,
            a highly conserved homolog of the human MAZ gene
  JOURNAL   Eur J Biochem 259 (3), 676-683 (1999)
   PUBMED   10092852
REFERENCE   10 (residues 1 to 493)
  AUTHORS   Kennedy,G.C. and Rutter,W.J.
  TITLE     Pur-1, a zinc-finger protein that binds to purine-rich sequences,
            transactivates an insulin promoter in heterologous cells
  JOURNAL   Proc Natl Acad Sci U S A 89 (23), 11498-11502 (1992)
   PUBMED   1454839
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122863.4.
            
            On Sep 3, 2019 this sequence version replaced XP_006507465.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.2376508.1,
                                           SRR7652917.226831.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 69.28 cM"
     Protein         1..493
                     /product="myc-associated zinc finger protein isoform 3"
                     /note="purine-binding transcription factor"
                     /calculated_mol_wt=51060
     Region          59..78
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (P56671.1)"
     Region          121..144
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (P56671.1)"
     Region          192..212
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          281..301
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(286,288,290,292..293,296..297,300,314,316,320..321,
                     324..325,328,344,346,348,350..351,354..355)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          <303..360
                     /region_name="SFP1"
                     /note="Putative transcriptional repressor regulating G2/M
                     transition [Transcription / Cell division and chromosome
                     partitioning]; COG5189"
                     /db_xref="CDD:227516"
     Region          309..329
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          339..357
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            361
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:P56270; propagated from
                     UniProtKB/Swiss-Prot (P56671.1)"
     Region          368..388
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          394..413
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          <400..>451
                     /region_name="KREPA"
                     /note="Kinetoplastid RNA Editing Protein A (KREPA);
                     cl49620"
                     /db_xref="CDD:483960"
     Region          421..437
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          454..474
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     CDS             1..493
                     /gene="Maz"
                     /gene_synonym="MAZI; Pur-1; PUR1; SAF-1; SAF-2"
                     /coded_by="NM_001372522.1:172..1653"
                     /note="isoform 3 is encoded by transcript variant 3"
                     /db_xref="CCDS:CCDS90332.1"
                     /db_xref="GeneID:17188"
                     /db_xref="MGI:MGI:1338823"
ORIGIN      
        1 mfpvfpctll appfpvlgld srgvgglmns fpppqghaqn plqvgaelqs rffasqgcaq
       61 spfqaapapp ptpqapaaep lqvdllpvla aaqesaaaaa aaaaaaaavv tappapaaas
      121 tvdtaalkqp pappppppav sapaaeaapp aaaatiaaaa atavvaptst vavapvasvl
      181 ekktkskgpy icalcakefk ngynlrrhea ihtgakagrv psgamkmptm vplsllsvpq
      241 lsgasgggge agagggtaav aaggvvttta sgkrirknha cemcgkafrd vyhlnrhkls
      301 hsdekpyqcp vcqqrfkrkd rmsyhvrshd gavhkpyncs hcgksfsrpd hlnshvrqvh
      361 sterpfkcek ceaafatkdr lrahtvrhee kvpchvcgkm lssayisdhm kvhsqgphhv
      421 celcnkgftt aaylrihavk dhglqaprad rilcklcsvh cktpaqlagh mqthlggaap
      481 pipgdapqpq ptc
//
