LOCUS       NM_026739               2189 bp    mRNA    linear   ROD 02-JUL-2024
DEFINITION  Mus musculus microtubule associated tyrosine carboxypeptidase 2
            (Matcap2), transcript variant 1, mRNA.
ACCESSION   NM_026739 XM_134635
VERSION     NM_026739.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2189)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2189)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2189)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 2189)
  AUTHORS   McClintock,T.S., Glasser,C.E., Bose,S.C. and Bergman,D.A.
  TITLE     Tissue expression patterns identify mouse cilia genes
  JOURNAL   Physiol Genomics 32 (2), 198-206 (2008)
   PUBMED   17971504
  REMARK    GeneRIF: 9530077C05Rik is most abundantly expressed in tissues rich
            in highly ciliated cells, such as olfactory sensory neurons, and is
            predicted to be important to cilia.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC093926.6.
            
            On Mar 17, 2020 this sequence version replaced NM_026739.2.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC054761.1, AK220359.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-203               AC093926.6         89185-89387         c
            204-898             AC093926.6         76127-76821         c
            899-1042            AC093926.6         70435-70578         c
            1043-1175           AC093926.6         69126-69258         c
            1176-1481           AC093926.6         65534-65839         c
            1482-1579           AC093926.6         60970-61067         c
            1580-2189           AC093926.6         56253-56862         c
FEATURES             Location/Qualifiers
     source          1..2189
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 9.14 cM"
     gene            1..2189
                     /gene="Matcap2"
                     /gene_synonym="1110003N12Rik; 9530077C05Rik; mKIAA0895"
                     /note="microtubule associated tyrosine carboxypeptidase 2"
                     /db_xref="GeneID:68283"
                     /db_xref="MGI:MGI:1915533"
     exon            1..203
                     /gene="Matcap2"
                     /gene_synonym="1110003N12Rik; 9530077C05Rik; mKIAA0895"
                     /inference="alignment:Splign:2.1.0"
     CDS             179..1738
                     /gene="Matcap2"
                     /gene_synonym="1110003N12Rik; 9530077C05Rik; mKIAA0895"
                     /note="isoform a is encoded by transcript variant 1;
                     putative tyrosine carboxypeptidase MATCAP2"
                     /codon_start=1
                     /product="putative tyrosine carboxypeptidase MATCAP2
                     isoform a"
                     /protein_id="NP_081015.1"
                     /db_xref="CCDS:CCDS40563.1"
                     /db_xref="GeneID:68283"
                     /db_xref="MGI:MGI:1915533"
                     /translation="MLESIRVTEKLHWPEHELAKKFVLNAEEALITDSKRSFSSLSSG
                     ILKDTFTTGTSSYNVLLQSKEEKKHRSQKRFSSASSKQHRKPSKSPSSSHSKDPSRMT
                     ALVPGTGAGTWYCLDGQSAVFVTSSVPSPVKFTRDISITGSGLALPPKPKSKVKRRNL
                     TRLPKPKQQPQLCRSFERGDDISGKKLCILTAIKPINLEKEKLRFFKSDYTYNPQFEY
                     ANPTLPGVLAKHSNASDRFLKQSINIMELTLQKYGSYEKFEQATGGSLLSKTRIWSHV
                     RKYMVKEGCLGEIVVHLTEDLLSRASMTVVNGCPTLTINISTAREHWLEGMLRHEIGT
                     HYFRGINNLQQPWNSWIGRKKHELKPNNPTEEGLASIHSVLFRKDPFLWRAALLYYTV
                     YKASHMSFCELFKDIGKFVKDPNTRWDYCVRAKRGWTDTSEPGCFSKDQVYLDGVLQI
                     LRFRESIDFHLLTALGKVSYEDVDRLKELAVTENMRVPHFLHDHSRYMEHLERIMEVN
                     ELTDAELKNLI"
     exon            204..898
                     /gene="Matcap2"
                     /gene_synonym="1110003N12Rik; 9530077C05Rik; mKIAA0895"
                     /inference="alignment:Splign:2.1.0"
     exon            899..1042
                     /gene="Matcap2"
                     /gene_synonym="1110003N12Rik; 9530077C05Rik; mKIAA0895"
                     /inference="alignment:Splign:2.1.0"
     exon            1043..1175
                     /gene="Matcap2"
                     /gene_synonym="1110003N12Rik; 9530077C05Rik; mKIAA0895"
                     /inference="alignment:Splign:2.1.0"
     exon            1176..1481
                     /gene="Matcap2"
                     /gene_synonym="1110003N12Rik; 9530077C05Rik; mKIAA0895"
                     /inference="alignment:Splign:2.1.0"
     exon            1482..1579
                     /gene="Matcap2"
                     /gene_synonym="1110003N12Rik; 9530077C05Rik; mKIAA0895"
                     /inference="alignment:Splign:2.1.0"
     exon            1580..2189
                     /gene="Matcap2"
                     /gene_synonym="1110003N12Rik; 9530077C05Rik; mKIAA0895"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2171..2176
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Matcap2"
                     /gene_synonym="1110003N12Rik; 9530077C05Rik; mKIAA0895"
                     /note="hexamer: ATTAAA"
     polyA_site      2189
                     /gene="Matcap2"
                     /gene_synonym="1110003N12Rik; 9530077C05Rik; mKIAA0895"
                     /note="major polyA site"
ORIGIN      
        1 accgtggcgg gttcttagct ctgagactag gtggaaccgc cagagcgctt tccagcctct
       61 gggtaagacg tggtcctcca ccttgcgctg ccagtcctgc cccatctggt ctcgagctgc
      121 cttacgggag ttttcgtcgg tgcggcccgc cggccttggc cttggccttg gcgggacgat
      181 gctggagtct attcgcgtaa cggaaaagct tcactggcct gaacatgaac ttgctaagaa
      241 gtttgttcta aatgcagaag aggcattgat cactgacagc aaaagaagct tttcgagttt
      301 gtcctctggg attctcaagg acactttcac aactggaacc agtagttaca atgttctact
      361 acagagcaag gaggagaaaa agcaccgttc acaaaagcgg ttttcctctg ccagctccaa
      421 acaacatagg aagcccagca aatctcctag ctcctctcat agcaaagatc ctagcaggat
      481 gacagccctg gtgcctggga caggcgctgg cacttggtac tgcctagacg ggcagtctgc
      541 tgtttttgtt actagctcag taccaagtcc tgtaaagttc acccgtgata tctctattac
      601 aggaagcggc ctagcactgc cacctaaacc aaaaagcaag gtcaaacgac gcaatctgac
      661 ccggcttcca aagccaaagc aacagcctca gctgtgtaga agctttgaga gaggagatga
      721 catttctggg aaaaagcttt gtatattgac tgctataaag cccatcaacc tggagaagga
      781 aaagctgcgg ttcttcaagt cggactatac ttacaaccct cagtttgagt atgccaatcc
      841 cactctgcca ggggtgttag ccaaacacag caacgcctct gaccggtttc ttaagcagtc
      901 catcaatatt atggagctga ctttacaaaa atatggaagt tatgaaaaat ttgaacaagc
      961 tactggtggt agcttgttgt ctaaaactcg aatctggagt catgttagaa agtacatggt
     1021 gaaggaaggc tgcctgggag agattgtagt tcatctcacc gaagacctgc tttccagggc
     1081 atccatgacg gtagtaaacg gatgcccgac tctaaccatc aatatttcta ctgcacgaga
     1141 gcactggctg gagggcatgc tgaggcacga gataggcaca cattattttc ggggtattaa
     1201 caaccttcag caaccgtgga acagttggat tggccgaaaa aaacatgagc taaagcccaa
     1261 caacccaacg gaggaagggc tggcaagcat ccacagtgtc ctgttcagaa aagacccctt
     1321 cctgtggagg gccgctctcc tgtactacac ggtgtataaa gccagccaca tgtccttctg
     1381 tgaactcttc aaagacattg gcaagtttgt caaggaccct aatacaagat gggactattg
     1441 tgtaagagcc aagagagggt ggactgacac ttctgagccc gggtgtttca gtaaggacca
     1501 ggtctacttg gatggagtcc ttcaaatcct gcgattcaga gagtccatag acttccatct
     1561 gctgactgcc ctgggcaagg tatcttacga agatgtggat cgcttaaaag aattggcagt
     1621 tactgaaaac atgcgagtcc cacatttcct tcatgatcac agccggtaca tggagcactt
     1681 agagaggatc atggaggtga acgagctgac agacgctgag ctgaaaaacc tcatctaagc
     1741 agcagagccg gctcttcatg gctgttagca gctagggcac ccagcacctg cagaactaga
     1801 ggagagcagc tgaccttcgc ttgttgaaga ccagctctca ggatccagct gaaattctag
     1861 gttccatgta gacctgaaac tattttccta gaacatttct atagacttcg ggtggaagtc
     1921 acttgtcttt tcattcagat ctctccagag acaaatgaag acttcgctgc tggtgacacc
     1981 acgatgagct gtgaacttgg gcaccaaggc cagctctgga ttggaggtgg ccagtctaat
     2041 gctctgcagt ataaacccca aggttctatt tcctctccta aacagagaga gttgttcttt
     2101 gaaatagcca ttttgtacac cagagaaggc tagcaatatc taagctctta tttttcttat
     2161 gttaagtaat attaaaagga gattgaaaa
//
