LOCUS       NM_172568               3074 bp    mRNA    linear   ROD 04-AUG-2023
DEFINITION  Mus musculus membrane associated ring-CH-type finger 10 (Marchf10),
            transcript variant 1, mRNA.
ACCESSION   NM_172568
VERSION     NM_172568.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3074)
  AUTHORS   Gaudet P, Livstone MS, Lewis SE and Thomas PD.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 3074)
  AUTHORS   Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen
            A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M,
            Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E,
            Mehmeti S, Dagand E, Schrinner S, Nurnberger A, Schmidt K, Metz K,
            Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe
            F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S,
            Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN,
            Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S,
            Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple
            CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P,
            Reymond A, Davidson DR, Dolle P, Antonarakis SE, Yaspo ML, Martinez
            S, Baldock RA, Eichele G and Ballabio A.
  TITLE     A high-resolution anatomical atlas of the transcriptome in the
            mouse embryo
  JOURNAL   PLoS Biol 9 (1), e1000582 (2011)
   PUBMED   21267068
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY099161.1, AK132734.1 and AL645684.16.
            
            [WARNING] On Mar 22, 2024 this sequence was replaced by
            NM_172568.3.
            
            On Nov 18, 2008 this sequence version replaced NM_172568.1.
            
            Transcript Variant: This transcript (1) encodes the longer protein
            (isoform 1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            transcript and genomic sequence to make the sequence consistent
            with the reference genome assembly. The genomic coordinates used
            for the transcript record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849384
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-11                BY099161.1         2-12
            12-740              AK132734.1         1-729
            741-887             AL645684.16        62001-62147         c
            888-2235            AL645684.16        54636-55983         c
            2236-2405           AL645684.16        50469-50638         c
            2406-2515           AL645684.16        47210-47319         c
            2516-2629           AL645684.16        36914-37027         c
            2630-2672           AL645684.16        29568-29610         c
            2673-3074           AL645684.16        25850-26251         c
FEATURES             Location/Qualifiers
     source          1..3074
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 68.73 cM"
     gene            1..3074
                     /gene="Marchf10"
                     /gene_synonym="4933417C16Rik; March10; Rnf190"
                     /note="membrane associated ring-CH-type finger 10"
                     /db_xref="GeneID:632687"
                     /db_xref="MGI:MGI:2443469"
     exon            1..262
                     /gene="Marchf10"
                     /gene_synonym="4933417C16Rik; March10; Rnf190"
                     /inference="alignment:Splign:2.1.0"
     exon            263..344
                     /gene="Marchf10"
                     /gene_synonym="4933417C16Rik; March10; Rnf190"
                     /inference="alignment:Splign:2.1.0"
     exon            345..451
                     /gene="Marchf10"
                     /gene_synonym="4933417C16Rik; March10; Rnf190"
                     /inference="alignment:Splign:2.1.0"
     CDS             362..2728
                     /gene="Marchf10"
                     /gene_synonym="4933417C16Rik; March10; Rnf190"
                     /EC_number="2.3.2.27"
                     /note="isoform 1 is encoded by transcript variant 1; ring
                     finger protein 190; membrane-associated ring finger
                     (C3HC4) 10"
                     /codon_start=1
                     /product="probable E3 ubiquitin-protein ligase MARCHF10
                     isoform 1"
                     /protein_id="NP_766156.2"
                     /db_xref="CCDS:CCDS48955.1"
                     /db_xref="GeneID:632687"
                     /db_xref="MGI:MGI:2443469"
                     /translation="MLHETRDRQKFVSDVQYLRDMQHKVDSEYQACLKRQENKKEPNE
                     KKQEQLWVRDTSDRSRFSSGSSCKQSSCEEDSRSEARLSTKTSSAKCEPRLPAIDQAS
                     VKQKHKGTMTLKKSEKVSPSKPSPVAPKILSRKRRPNLGRLTVSPEMHSPRASAERSR
                     QKPQLSTKASGLLGADPVVQQESLLCANETKLKKPARERRKLAPSSQLMRTAGKPREK
                     QKKGDLSAHPQNEPHTALSQTFQPMNGSQMLNESLGPSLLPATVVGPRRTPFRFHDED
                     FYSAISLNNEQESYDTEEETHMEEELLLSGMRSPPSYKRSRFLGTSTAQNRNVEENAE
                     NLRGNSLRWSEPSPGSPRKTSTTEPATKQPSPGQRMLQDTRLPSELAKENPSGDQDEK
                     TPVLGDAKSDGVIQVSADDVSSGGTVEDRSAVQNHERDWQHYYSGSRTSFDCLLSGRP
                     TAPRSSMNPPYSAHGSLLHSALIDDIPANLSMSSILVPSSDLEENLRFNVRRPLSPIR
                     NRNPLAAAEGRSDEAQGTQEMASTSHIQEPPLLADLPNPQSSVALGDSPSSPTRRHLQ
                     GHFYMPGSLQENIPFTFFAVSDFANQNDNGTTVRVSGVMDEKATEIKADPEKLRKLQE
                     SLLEEDSEEEEGDLCRICQIAGGSPANPLLEPCGCVGSLQFVHQECLKKWLKVKITSG
                     ADLGTVKTCEMCKQGLLVDLDDFNMTEFYHKHQQSRAQSELMNSGLYLVLLLHLYEQR
                     FAELMALNYRRASRERLSRNYPQPRPEENESSESGDGNASNIYPGRVI"
     exon            452..568
                     /gene="Marchf10"
                     /gene_synonym="4933417C16Rik; March10; Rnf190"
                     /inference="alignment:Splign:2.1.0"
     exon            569..740
                     /gene="Marchf10"
                     /gene_synonym="4933417C16Rik; March10; Rnf190"
                     /inference="alignment:Splign:2.1.0"
     exon            741..887
                     /gene="Marchf10"
                     /gene_synonym="4933417C16Rik; March10; Rnf190"
                     /inference="alignment:Splign:2.1.0"
     exon            888..2235
                     /gene="Marchf10"
                     /gene_synonym="4933417C16Rik; March10; Rnf190"
                     /inference="alignment:Splign:2.1.0"
     exon            2236..2405
                     /gene="Marchf10"
                     /gene_synonym="4933417C16Rik; March10; Rnf190"
                     /inference="alignment:Splign:2.1.0"
     exon            2406..2515
                     /gene="Marchf10"
                     /gene_synonym="4933417C16Rik; March10; Rnf190"
                     /inference="alignment:Splign:2.1.0"
     exon            2516..2629
                     /gene="Marchf10"
                     /gene_synonym="4933417C16Rik; March10; Rnf190"
                     /inference="alignment:Splign:2.1.0"
     exon            2630..2672
                     /gene="Marchf10"
                     /gene_synonym="4933417C16Rik; March10; Rnf190"
                     /inference="alignment:Splign:2.1.0"
     exon            2673..3074
                     /gene="Marchf10"
                     /gene_synonym="4933417C16Rik; March10; Rnf190"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3052..3057
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Marchf10"
                     /gene_synonym="4933417C16Rik; March10; Rnf190"
     polyA_site      3074
                     /gene="Marchf10"
                     /gene_synonym="4933417C16Rik; March10; Rnf190"
ORIGIN      
        1 ggttgccaag gaaacgggag gacgccaggc agccgccccc accgtctcca ccccaagaaa
       61 ggccggaggc cgcggcggac agctgcctcc cgggaggaga aggaagaggg ccctctagaa
      121 ggagggaaga cagtgaggtg tgggggagga agaggagccc aggaccggcc ccacgcacga
      181 ttgatgggcg gctcttcgcc cacccgctcc gccccgcggc ccctttagcc ccttgtgagg
      241 ggtgaaagtg ctgatcccca aggagcagca ggggatccat ctttctgttt ttaaccccat
      301 cgtttttttt ctgaaaaagg gggaacagac ttcattctat gcagatcagg aactaagaac
      361 catgttgcat gaaacaaggg acaggcagaa gttcgtcagc gatgttcagt atctacggga
      421 tatgcagcat aaggtggact cagaatatca ggcttgtttg aaacgacagg aaaacaagaa
      481 agaaccaaat gagaagaagc aggagcagct gtgggtgaga gatacaagtg acaggtcgcg
      541 gttttcaagc gggtcgtcat gcaaacagag ttcctgtgag gaggattctc gcagtgaagc
      601 aagattatct accaaaacat cttcggctaa gtgtgagccc agacttccag ccattgacca
      661 agcatctgtc aagcagaaac acaaaggcac catgacacta aagaagtcag agaaagtgag
      721 ccccagcaaa ccctctccag tggcaccaaa gattttatca aggaagagga gaccaaacct
      781 ggggagattg acagtcagcc cagagatgca cagcccaaga gcatctgcgg agagaagcag
      841 gcagaaacca cagctgtcga caaaggcatc aggactcctg ggagcagacc cagttgtcca
      901 acaagaaagc ctgctgtgtg caaatgagac taagctaaag aagccagctc gagagagaag
      961 aaagttagcc ccatcttcac aactcatgag aacggctggg aagccccgcg agaaacagaa
     1021 aaaaggagac ctgagtgctc atccccagaa cgagccccac actgccctct cacagacatt
     1081 ccagccaatg aatggttctc aaatgctgaa tgagtccttg ggaccttcac tcctccccgc
     1141 caccgtggta ggaccaagaa ggacaccatt taggttccat gacgaagatt tttattctgc
     1201 aatatcacta aacaatgaac aagagagcta tgacacggaa gaggagactc acatggagga
     1261 agagctcctg ctgtctggga tgcgctctcc tcccagctat aaaaggagcc ggtttctcgg
     1321 gacatcaact gctcaaaata gaaatgtgga ggaaaatgct gaaaatctca gaggaaattc
     1381 tctaagatgg agtgagccca gccctggatc tccaagaaaa accagtacca cagagccagc
     1441 aacaaagcag ccttctcctg ggcaaaggat gctccaagat accaggttac ccagtgagtt
     1501 ggctaaagag aaccccagtg gagaccaaga tgagaagacc cctgttctag gggatgcgaa
     1561 atctgatggt gttatccagg tcagtgctga cgatgtgtcc agcggtggta ctgtggaaga
     1621 caggtctgct gttcaaaatc acgagagaga ctggcaacat tactatagtg gttctaggac
     1681 ctcatttgac tgcttacttt ctgggaggcc cacagctcca agatcatcca tgaatccacc
     1741 ttacagtgct catgggtcac tgctccattc tgctctgata gacgacatcc cggcaaactt
     1801 gtccatgtca tctatcctag tcccaagttc agacttggag gaaaacctaa ggtttaatgt
     1861 acgccggcca ctctcaccca tcagaaatag aaatccattg gccgctgctg aaggccgcag
     1921 tgatgaagcc cagggtacac aggagatggc ttcaacgagt cacattcagg agcctccatt
     1981 actggcagat ctaccaaatc cacaaagcag tgtggcctta ggggactctc ccagctctcc
     2041 tacaagacga catttacaag gccatttcta catgcctggg tccctgcagg aaaatatacc
     2101 ttttactttc tttgcagtat ctgattttgc aaatcaaaat gataacggaa ccaccgttag
     2161 agtctctggt gtcatggatg aaaaggccac agaaataaag gcagatcctg agaagctcag
     2221 gaaattgcaa gaaagtctcc tggaggagga ctcggaagag gaggagggag acttgtgtcg
     2281 aatctgtcag atagccgggg gttccccagc caaccccctc ctggagcctt gcggctgtgt
     2341 gggaagtcta cagtttgttc accaagagtg cctgaaaaag tggctgaaag tgaaaataac
     2401 atcaggagca gatctaggca ctgtaaagac ctgtgagatg tgtaagcaag gcctactggt
     2461 cgacctggat gacttcaaca tgaccgaatt ctaccacaag caccagcaat cccgggcaca
     2521 gagtgagctg atgaactcag gcttgtacct ggtgctgctg ctgcacctat atgagcagag
     2581 gttcgcggag ctcatggcac tcaactacag gcgggcttcc agagagaggt tgtcaagaaa
     2641 ttacccacaa cccagaccgg aagaaaatga aagttccgag tcgggagatg gtaatgcaag
     2701 caacatttac ccaggccggg tcatctagca agggagctgg tcgtggagtg cggcagagac
     2761 ctctccaccc agaagccctt tctgtgtccc cctctgcctc ccttcttccc tcctctttat
     2821 tgaaaccaat gtgttcgcag ttaccatttt cacccgtgcc actccttctt ggggtctggc
     2881 ttgagcatcc gtgggcagcc acagggacca tcccagccag cacaggcaaa acagctgagt
     2941 cccccgtgtg ctgccctgct gctgcccctc agcccagcag cctgggctcc cagtgctgag
     3001 gccctctgtt caggcctccg cccaccctga gtggaatgga gccatgcatt cagtaaactg
     3061 actttattct ccca
//
