LOCUS       NM_001081124            3682 bp    mRNA    linear   ROD 14-JAN-2025
DEFINITION  Mus musculus MAP7 domain containing 2 (Map7d2), transcript variant
            1, mRNA.
ACCESSION   NM_001081124 XM_136135
VERSION     NM_001081124.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3682)
  AUTHORS   Kikuchi,K., Sakamoto,Y., Uezu,A., Yamamoto,H., Ishiguro,K.I.,
            Shimamura,K., Saito,T., Hisanaga,S.I. and Nakanishi,H.
  TITLE     Map7D2 and Map7D1 facilitate microtubule stabilization through
            distinct mechanisms in neuronal cells
  JOURNAL   Life Sci Alliance 5 (8), e202201390 (2022)
   PUBMED   35470240
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3682)
  AUTHORS   Pan,X., Cao,Y., Stucchi,R., Hooikaas,P.J., Portegies,S., Will,L.,
            Martin,M., Akhmanova,A., Harterink,M. and Hoogenraad,C.C.
  TITLE     MAP7D2 Localizes to the Proximal Axon and Locally Promotes
            Kinesin-1-Mediated Cargo Transport into the Axon
  JOURNAL   Cell Rep 26 (8), 1988-1999 (2019)
   PUBMED   30784582
REFERENCE   3  (bases 1 to 3682)
  AUTHORS   Cox,B.J., Vollmer,M., Tamplin,O., Lu,M., Biechele,S.,
            Gertsenstein,M., van Campenhout,C., Floss,T., Kuhn,R., Wurst,W.,
            Lickert,H. and Rossant,J.
  TITLE     Phenotypic annotation of the mouse X chromosome
  JOURNAL   Genome Res 20 (8), 1154-1164 (2010)
   PUBMED   20548051
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CK620800.1, AK013466.1, AL672284.15, AK030316.1 and BE952779.1.
            
            On Sep 1, 2015 this sequence version replaced NM_001081124.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660815.250561.1,
                                           SRR1660821.98443.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-496               CK620800.1         1-496
            497-723             AK013466.1         282-508
            724-724             AL672284.15        57218-57218
            725-870             AK013466.1         509-654
            871-3496            AK030316.1         367-2992
            3497-3682           BE952779.1         1-186               c
FEATURES             Location/Qualifiers
     source          1..3682
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 73.45 cM"
     gene            1..3682
                     /gene="Map7d2"
                     /gene_synonym="1600028E09Rik; 2900002G04Rik;
                     5330432J06Rik; C030036K04Rik; Mtap7d2"
                     /note="MAP7 domain containing 2"
                     /db_xref="GeneID:78283"
                     /db_xref="MGI:MGI:1917474"
     exon            1..321
                     /gene="Map7d2"
                     /gene_synonym="1600028E09Rik; 2900002G04Rik;
                     5330432J06Rik; C030036K04Rik; Mtap7d2"
                     /inference="alignment:Splign:2.1.0"
     CDS             126..2471
                     /gene="Map7d2"
                     /gene_synonym="1600028E09Rik; 2900002G04Rik;
                     5330432J06Rik; C030036K04Rik; Mtap7d2"
                     /note="isoform 1 is encoded by transcript variant 1; MAP7
                     domain-containing protein 2; novel E-MAP-115 family
                     protein"
                     /codon_start=1
                     /product="MAP7 domain-containing protein 2 isoform 1"
                     /protein_id="NP_001074593.1"
                     /db_xref="CCDS:CCDS41193.1"
                     /db_xref="GeneID:78283"
                     /db_xref="MGI:MGI:1917474"
                     /translation="MERSGGNGGGGGGGGGGGGGYGGSGGGGGGAGVPSEGAAKGLSL
                     LLAKSAEAASGRASQSTPRSAGMDGFLKSDERQRLAKERREEREKCLAAREQQILEKQ
                     KRAKLQYEKQIEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMRRSLERT
                     QQLELKKKCSWAGSPGPGGRDGESENTPPLPLTLATSTPPLDTGTTTAAAESTNACDK
                     LSTSTMNLPKQTESPMSKHLSSSTVAISYSPDRALGSPLKSSYKSSPTRTTEKKKNTP
                     ISAMGDAGKGAMAGGEPSQMEKMKKGRVATSAASGGHGSPLRRCEPPEDISKRLSSPV
                     KSKITSKTYPQSPKTAKPTYLGSPVKYYFPPIANEETPKKKAEKEKRNKEKEGAPGQQ
                     STVLPREESLEKRMADKYATEKYVADKHATEKHSAPGGKAEHSAGKPTAGTTDAGEAA
                     KILAEKRRQARLQKEQEEQERLEKEERERLEKEELKRKAEEERLRIEMAYKREQEKKR
                     QEEEEKRKAEEKAKEKAEEELLSKEKQEKEKQEQEKKEKAMIEKQKEAAEAKAQDAAK
                     QMRLEREQIMLQIEQERLERKKRIDEIMKRTRKSDASLEVKKEDPKVELQPPPDVENK
                     ANKAKPVVPNKIEINVLNTCQKVSGSERAAPETFPQDIFSTGLKPVGGPVHLDVLDGK
                     SNSLDDSTEDVQSMDVSPVSKEELISIPEFSPVSEMIPGMSLDQNGTGNARALQDILD
                     FTGPPAFPKKSSENLSLDDCNKNLIEGFNSPGQETTLNTFC"
     exon            322..399
                     /gene="Map7d2"
                     /gene_synonym="1600028E09Rik; 2900002G04Rik;
                     5330432J06Rik; C030036K04Rik; Mtap7d2"
                     /inference="alignment:Splign:2.1.0"
     exon            400..563
                     /gene="Map7d2"
                     /gene_synonym="1600028E09Rik; 2900002G04Rik;
                     5330432J06Rik; C030036K04Rik; Mtap7d2"
                     /inference="alignment:Splign:2.1.0"
     exon            564..669
                     /gene="Map7d2"
                     /gene_synonym="1600028E09Rik; 2900002G04Rik;
                     5330432J06Rik; C030036K04Rik; Mtap7d2"
                     /inference="alignment:Splign:2.1.0"
     exon            670..768
                     /gene="Map7d2"
                     /gene_synonym="1600028E09Rik; 2900002G04Rik;
                     5330432J06Rik; C030036K04Rik; Mtap7d2"
                     /inference="alignment:Splign:2.1.0"
     exon            769..879
                     /gene="Map7d2"
                     /gene_synonym="1600028E09Rik; 2900002G04Rik;
                     5330432J06Rik; C030036K04Rik; Mtap7d2"
                     /inference="alignment:Splign:2.1.0"
     exon            880..1010
                     /gene="Map7d2"
                     /gene_synonym="1600028E09Rik; 2900002G04Rik;
                     5330432J06Rik; C030036K04Rik; Mtap7d2"
                     /inference="alignment:Splign:2.1.0"
     exon            1011..1135
                     /gene="Map7d2"
                     /gene_synonym="1600028E09Rik; 2900002G04Rik;
                     5330432J06Rik; C030036K04Rik; Mtap7d2"
                     /inference="alignment:Splign:2.1.0"
     exon            1136..1434
                     /gene="Map7d2"
                     /gene_synonym="1600028E09Rik; 2900002G04Rik;
                     5330432J06Rik; C030036K04Rik; Mtap7d2"
                     /inference="alignment:Splign:2.1.0"
     exon            1435..1561
                     /gene="Map7d2"
                     /gene_synonym="1600028E09Rik; 2900002G04Rik;
                     5330432J06Rik; C030036K04Rik; Mtap7d2"
                     /inference="alignment:Splign:2.1.0"
     exon            1562..1784
                     /gene="Map7d2"
                     /gene_synonym="1600028E09Rik; 2900002G04Rik;
                     5330432J06Rik; C030036K04Rik; Mtap7d2"
                     /inference="alignment:Splign:2.1.0"
     exon            1785..1889
                     /gene="Map7d2"
                     /gene_synonym="1600028E09Rik; 2900002G04Rik;
                     5330432J06Rik; C030036K04Rik; Mtap7d2"
                     /inference="alignment:Splign:2.1.0"
     exon            1890..1946
                     /gene="Map7d2"
                     /gene_synonym="1600028E09Rik; 2900002G04Rik;
                     5330432J06Rik; C030036K04Rik; Mtap7d2"
                     /inference="alignment:Splign:2.1.0"
     exon            1947..2034
                     /gene="Map7d2"
                     /gene_synonym="1600028E09Rik; 2900002G04Rik;
                     5330432J06Rik; C030036K04Rik; Mtap7d2"
                     /inference="alignment:Splign:2.1.0"
     exon            2035..2221
                     /gene="Map7d2"
                     /gene_synonym="1600028E09Rik; 2900002G04Rik;
                     5330432J06Rik; C030036K04Rik; Mtap7d2"
                     /inference="alignment:Splign:2.1.0"
     exon            2222..2496
                     /gene="Map7d2"
                     /gene_synonym="1600028E09Rik; 2900002G04Rik;
                     5330432J06Rik; C030036K04Rik; Mtap7d2"
                     /inference="alignment:Splign:2.1.0"
     exon            2497..3670
                     /gene="Map7d2"
                     /gene_synonym="1600028E09Rik; 2900002G04Rik;
                     5330432J06Rik; C030036K04Rik; Mtap7d2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3476..3481
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Map7d2"
                     /gene_synonym="1600028E09Rik; 2900002G04Rik;
                     5330432J06Rik; C030036K04Rik; Mtap7d2"
                     /note="hexamer: ATTAAA"
     polyA_site      3499
                     /gene="Map7d2"
                     /gene_synonym="1600028E09Rik; 2900002G04Rik;
                     5330432J06Rik; C030036K04Rik; Mtap7d2"
     regulatory      3648..3653
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Map7d2"
                     /gene_synonym="1600028E09Rik; 2900002G04Rik;
                     5330432J06Rik; C030036K04Rik; Mtap7d2"
                     /note="hexamer: AATAAA"
     regulatory      3653..3658
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Map7d2"
                     /gene_synonym="1600028E09Rik; 2900002G04Rik;
                     5330432J06Rik; C030036K04Rik; Mtap7d2"
                     /note="hexamer: AATACA"
     polyA_site      3667
                     /gene="Map7d2"
                     /gene_synonym="1600028E09Rik; 2900002G04Rik;
                     5330432J06Rik; C030036K04Rik; Mtap7d2"
                     /note="major polyA site"
     polyA_site      3670
                     /gene="Map7d2"
                     /gene_synonym="1600028E09Rik; 2900002G04Rik;
                     5330432J06Rik; C030036K04Rik; Mtap7d2"
ORIGIN      
        1 gcgagcccgg gcagagggag gccggcgcgc aaggtgggag gccgcgtgcg catgcggacc
       61 cgcgcggggc cggtgcgaca cagcgggcgg gccagacagt gcgcctgtgc agcccgcgca
      121 tcccgatgga gcgcagcggt gggaacggcg gcggcggcgg tggcggcggc ggcggcggcg
      181 gcgggtacgg cggcagcggt ggcggtggcg gaggagccgg agtcccctcg gaaggggctg
      241 ccaagggctt gtcgctgctg ctggccaagt ccgcggaagc ggcctccggg agagcctccc
      301 agtccacccc gcggtccgca ggaatggatg gatttttaaa atcagatgag agacaaagat
      361 tagccaaaga gagacgagaa gaaagagaaa aatgtctggc tgctcgggaa caacagatct
      421 tagagaaaca gaagagagcc aagcttcagt atgagaaaca aattgaggag cgatggagaa
      481 aacttgagga gcagcgccaa cgggaggatc agaagagggc agcagtggaa gagaagagga
      541 agcagaagct ccgggaagaa gaggagcgcc tggaagcaat gatgcgccgg tccctggagc
      601 gtacacaaca gctagagctg aagaagaagt gctcatgggc aggatcacca gggcctggcg
      661 gacgtgatgg tgaatcagaa aataccccac cccttcctct aactttagca accagcaccc
      721 cccctttgga cacagggacc actacagctg ctgccgagtc caccaacgca tgtgacaaac
      781 tttcaacatc aaccatgaat ttgccaaagc agacggagtc tcctatgagt aaacacctgt
      841 cttcatccac cgtggcaata tcttattccc cagaccgagc tctcgggagc cctctcaaat
      901 cttcatacaa gtcctctcca acccggacca ctgagaaaaa gaagaataca cctatatctg
      961 ccatgggaga tgctgggaag ggagccatgg ctggaggaga gccttcacag atggagaaaa
     1021 tgaagaaggg gcgagtggca acttctgctg cttctggggg tcatgggtcc ccactgagaa
     1081 gatgcgagcc tcctgaagat atttccaaga ggttgtcttc tcctgtgaaa tccaagataa
     1141 cttcaaaaac atatccacag tcgccaaaga cagcgaagcc cacatactta gggtctcctg
     1201 tgaagtatta ctttccaccc attgcaaacg aagaaacacc aaagaagaag gcagagaagg
     1261 agaagagaaa taaggaaaag gaaggtgccc ctggtcagca gagcactgtc ctacctagag
     1321 aagaaagcct agagaagcgc atggctgaca agtatgccac cgagaagtat gtagcagata
     1381 agcatgcaac tgagaaacat tctgcccctg gaggaaaggc tgagcacagt gcaggaaaac
     1441 ccacagcagg caccactgat gcaggagagg ctgcaaagat cctagctgaa aagagacgtc
     1501 aggctcggct acagaaggaa caagaggagc aagagcgact ggaaaaggaa gaacgagaaa
     1561 ggctggaaaa agaggaattg aaaagaaagg cagaagagga aaggctgcgc atagaaatgg
     1621 cctataaacg agaacaggaa aaaaagcggc aggaggaaga agagaaaaga aaagcagaag
     1681 agaaggcaaa agagaaggct gaggaggagc tcttgtcaaa agagaagcaa gaaaaggaaa
     1741 aacaagaaca agaaaagaag gaaaaagcca tgattgaaaa acagaaagaa gcagcagaag
     1801 caaaggcgca ggatgctgct aaacagatgc gtttagaaag agaacagatc atgctgcaga
     1861 ttgagcagga acgactggag aggaagaaga gaatagatga aatcatgaag agaacaagga
     1921 agagtgatgc gtctctagaa gtgaagaagg aagaccccaa agtggagctg cagcctcctc
     1981 cagatgttga aaataaagca aacaaagcaa agccagttgt ccccaacaag atcgaaatca
     2041 atgtgttgaa cacctgccag aaagtaagtg gctcagagcg tgctgctcca gaaacctttc
     2101 cccaagacat tttctctact ggccttaaac cagttggggg acctgttcat ctggatgtcc
     2161 ttgatgggaa atcaaacagt ctggatgact caactgaaga cgttcagtct atggatgtga
     2221 gtcctgtttc caaagaagaa cttatctcca tcccagagtt ttcaccagtg agtgaaatga
     2281 ttcctgggat gtctctggac caaaatggaa ctggtaatgc ccgggcactt caagatatct
     2341 tagatttcac tggccctccc gcattcccca agaaatccag tgaaaacctc agccttgatg
     2401 actgtaacaa aaacctcatc gaaggattta acagtcccgg gcaagaaact accctgaata
     2461 ccttctgttg acaaagacag cgttccttta agaaaggtgg tgtttggatc accctcgaag
     2521 ctgtcggtgt tgcatctgag ctgctggccg cctgaagaag cttcttttgc ccttaactgc
     2581 tgggctccaa attactagat tcaaaatgta actgtattcc taggtagttt ggcaaaccct
     2641 ggcctctctt ggtagaaacc ttgcgagttt tgctttgtgg ggctttagca gagtttcatt
     2701 gtatggttct ccttatgagc ttcagctgct gctaaagccc ttccttgacc ttctctacta
     2761 tcatagcctg tgtgatgctg tctgggaacc ctactctagg acactcgaat tcccagagat
     2821 ggagcacaga gacatttaga tgtctctttc tataaaaatc ttctatttac ccacactcta
     2881 gttaaacgtg tactactcaa cctggctgct tctctccctg tcttttgtgt gtgtgtatgg
     2941 ggtgagggaa atctagctac tttctccccg tctcaggatt ctgttatttt attattaagc
     3001 tccatcatct gcagagcatt actctccttt actgtttagg ggttgaagaa aggtttggtt
     3061 gaatgaataa gtaaatagtg gcaattattt cttttccctt atgggagctg aatctagcaa
     3121 ggaccctttc atgtcacccc tttaaaatcg ccaaattgtt gctccaaacc attgaatggc
     3181 ttttcagctg aatgaatcaa gtaacataca ggtggctatt ttcatggttt tgctgttgtt
     3241 tttctattag atcttggaat tttcttttgt ttgctcctgc atttgactaa ctgtaataaa
     3301 aaaaaagagt cagtgctttg aaagggggcc ccaagttggt cccagtatgt cactttaata
     3361 gactttaaac attcaaaagt ctgaacaagg aaaatgacac tagaatgtat aactccatgt
     3421 atgccatatg ctatatttaa atgtttcatt tcttgtggtg aaatgtagct ttattattaa
     3481 aatgaccttt tctttggaac tttttgtttt gacttgtacc ttaaagcttt tgaaaagatc
     3541 cttaattctg agaattacaa acagaagata gaaagaagtc ttaaagctgg tacagttaaa
     3601 gaatgtatta gtctcagaag ctgtgtatgt ttatgtgata gaatctaaat aaaatacaga
     3661 catctaagaa aaaaaaaaaa aa
//
