LOCUS       NM_001347198            3291 bp    mRNA    linear   ROD 14-JAN-2025
DEFINITION  Mus musculus MAP7 domain containing 1 (Map7d1), transcript variant
            3, mRNA.
ACCESSION   NM_001347198 XM_006503110
VERSION     NM_001347198.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3291)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3291)
  AUTHORS   Kikuchi,K., Sakamoto,Y., Uezu,A., Yamamoto,H., Ishiguro,K.I.,
            Shimamura,K., Saito,T., Hisanaga,S.I. and Nakanishi,H.
  TITLE     Map7D2 and Map7D1 facilitate microtubule stabilization through
            distinct mechanisms in neuronal cells
  JOURNAL   Life Sci Alliance 5 (8), e202201390 (2022)
   PUBMED   35470240
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3291)
  AUTHORS   Koizumi,H., Fujioka,H., Togashi,K., Thompson,J., Yates,J.R. 3rd,
            Gleeson,J.G. and Emoto,K.
  TITLE     DCLK1 phosphorylates the microtubule-associated protein MAP7D1 to
            promote axon elongation in cortical neurons
  JOURNAL   Dev Neurobiol 77 (4), 493-510 (2017)
   PUBMED   27503845
  REMARK    GeneRIF: Overexpression of a phosphomimetic MAP7D1 mutant in which
            Ser 315 is substituted with glutamic acid (MAP7D1 S315E), but not
            wild-type MAP7D1, fully rescues the axon elongation defects in
            Dclk1 knockdown neurons.
REFERENCE   4  (bases 1 to 3291)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL732624.6.
            
            On Nov 18, 2016 this sequence version replaced XM_006503110.3.
            
            Transcript Variant: This variant (3) lacks an alternate in-frame
            segment compared to variant 1. The resulting isoform (3) has the
            same N- and C-termini but is shorter compared to isoform 1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7652917.13684.1,
                                           SRR7345562.3279955.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-303               AL732624.6         80973-81275         c
            304-654             AL732624.6         66973-67323         c
            655-723             AL732624.6         66737-66805         c
            724-887             AL732624.6         65670-65833         c
            888-1002            AL732624.6         64979-65093         c
            1003-1113           AL732624.6         63478-63588         c
            1114-1236           AL732624.6         62112-62234         c
            1237-1400           AL732624.6         61852-62015         c
            1401-1540           AL732624.6         61589-61728         c
            1541-1869           AL732624.6         59723-60051         c
            1870-2065           AL732624.6         59279-59474         c
            2066-2204           AL732624.6         59054-59192         c
            2205-2309           AL732624.6         58849-58953         c
            2310-2363           AL732624.6         58549-58602         c
            2364-2406           AL732624.6         58321-58363         c
            2407-2497           AL732624.6         58132-58222         c
            2498-2691           AL732624.6         57824-58017         c
            2692-3291           AL732624.6         57123-57722         c
FEATURES             Location/Qualifiers
     source          1..3291
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 60.16 cM"
     gene            1..3291
                     /gene="Map7d1"
                     /gene_synonym="mKIAA1187; Mtap7d1; Parcc1; Rprc1"
                     /note="MAP7 domain containing 1"
                     /db_xref="GeneID:245877"
                     /db_xref="MGI:MGI:2384297"
     exon            1..303
                     /gene="Map7d1"
                     /gene_synonym="mKIAA1187; Mtap7d1; Parcc1; Rprc1"
                     /inference="alignment:Splign:2.1.0"
     CDS             258..2702
                     /gene="Map7d1"
                     /gene_synonym="mKIAA1187; Mtap7d1; Parcc1; Rprc1"
                     /note="isoform 3 is encoded by transcript variant 3;
                     proline arginine rich coiled coil 1; MAP7
                     domain-containing protein 1; arginine/proline rich
                     coiled-coil 1; microtubule-associated protein 7 domain
                     containing 1"
                     /codon_start=1
                     /product="MAP7 domain-containing protein 1 isoform 3"
                     /protein_id="NP_001334127.1"
                     /db_xref="CCDS:CCDS84793.1"
                     /db_xref="GeneID:245877"
                     /db_xref="MGI:MGI:2384297"
                     /translation="MESGPRVEPGPGAPAAVLARIPQEPRPSPEGDPSPPPPPTPMSA
                     LVPDTPPDTPPALKTATNPKQLPLEPGNPTGQISPQPAPPQEECPSSEAKSRGPTPTA
                     TGPREAKPSRRSSQPSPTTVPASDSPPAKQDVKKAGERHKLAKERREERAKYLAAKKA
                     VWLEKEEKAKALREKQLQERRRRLEEQRLKAEQRRAALEERQRQKLEKNKERYEAAIQ
                     RSVKKTWAEIRQQRWSWAGALHHSSPGRKTSGSRCSVSAVNLPKHVDSIINKRLSKSS
                     ATLWNSPSRNRSLQLSAWESSIVDRLMTPTLSFLARSRSAVTLPRNGRDQAVPVCPRS
                     ASASPLTPCSAPRSAHRCTPSGERPERRKPGAGGSPALARRRLEATPVQKKEKKDKER
                     ENEKEKSALARERNLKKRQSLPASIRPRLSTGSELSPKSKARPSSPSTTWHRPASPCP
                     SPGPGHALPPKPPSPRGTTASPKGRVRRKEEAKESPSPSGPEDKNHRKSRAAEEKEPA
                     APASPAPSPVPSPTPAQPQKEQSSTQIPAETAVPAVPAAPTAPPTAAPSVTPSKPMAG
                     TTDREEATRLLAEKRRQAREQREREEQERKLQAERDKRMREEQLAREAEARAEREAEA
                     RRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRQEREKHFQKEEQERQER
                     RKRLEEIMKRTRKSEAAETKKQDAKETAANNSGPDPVKAVETRPSGLQKDSMQKEELA
                     PQEPQWSLPSKEMPGSLVNGLQPLPAHQENGFSPKGTAGDKSLGRTAEGLLPFAEAEA
                     FLKKAVVQPPQVTEVL"
     exon            304..654
                     /gene="Map7d1"
                     /gene_synonym="mKIAA1187; Mtap7d1; Parcc1; Rprc1"
                     /inference="alignment:Splign:2.1.0"
     exon            655..723
                     /gene="Map7d1"
                     /gene_synonym="mKIAA1187; Mtap7d1; Parcc1; Rprc1"
                     /inference="alignment:Splign:2.1.0"
     exon            724..887
                     /gene="Map7d1"
                     /gene_synonym="mKIAA1187; Mtap7d1; Parcc1; Rprc1"
                     /inference="alignment:Splign:2.1.0"
     exon            888..1002
                     /gene="Map7d1"
                     /gene_synonym="mKIAA1187; Mtap7d1; Parcc1; Rprc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1003..1113
                     /gene="Map7d1"
                     /gene_synonym="mKIAA1187; Mtap7d1; Parcc1; Rprc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1114..1236
                     /gene="Map7d1"
                     /gene_synonym="mKIAA1187; Mtap7d1; Parcc1; Rprc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1237..1400
                     /gene="Map7d1"
                     /gene_synonym="mKIAA1187; Mtap7d1; Parcc1; Rprc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1401..1540
                     /gene="Map7d1"
                     /gene_synonym="mKIAA1187; Mtap7d1; Parcc1; Rprc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1541..1869
                     /gene="Map7d1"
                     /gene_synonym="mKIAA1187; Mtap7d1; Parcc1; Rprc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1870..2065
                     /gene="Map7d1"
                     /gene_synonym="mKIAA1187; Mtap7d1; Parcc1; Rprc1"
                     /inference="alignment:Splign:2.1.0"
     exon            2066..2204
                     /gene="Map7d1"
                     /gene_synonym="mKIAA1187; Mtap7d1; Parcc1; Rprc1"
                     /inference="alignment:Splign:2.1.0"
     exon            2205..2309
                     /gene="Map7d1"
                     /gene_synonym="mKIAA1187; Mtap7d1; Parcc1; Rprc1"
                     /inference="alignment:Splign:2.1.0"
     exon            2310..2363
                     /gene="Map7d1"
                     /gene_synonym="mKIAA1187; Mtap7d1; Parcc1; Rprc1"
                     /inference="alignment:Splign:2.1.0"
     exon            2364..2406
                     /gene="Map7d1"
                     /gene_synonym="mKIAA1187; Mtap7d1; Parcc1; Rprc1"
                     /inference="alignment:Splign:2.1.0"
     exon            2407..2497
                     /gene="Map7d1"
                     /gene_synonym="mKIAA1187; Mtap7d1; Parcc1; Rprc1"
                     /inference="alignment:Splign:2.1.0"
     exon            2498..2691
                     /gene="Map7d1"
                     /gene_synonym="mKIAA1187; Mtap7d1; Parcc1; Rprc1"
                     /inference="alignment:Splign:2.1.0"
     exon            2692..3291
                     /gene="Map7d1"
                     /gene_synonym="mKIAA1187; Mtap7d1; Parcc1; Rprc1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3266..3271
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Map7d1"
                     /gene_synonym="mKIAA1187; Mtap7d1; Parcc1; Rprc1"
                     /note="hexamer: AATAAA"
     polyA_site      3291
                     /gene="Map7d1"
                     /gene_synonym="mKIAA1187; Mtap7d1; Parcc1; Rprc1"
                     /note="major polyA site"
ORIGIN      
        1 gccgcgacca ggactgggcc ggcgcggggc aaaggagcag aatcgcggtc gcggaggacc
       61 gacctcgggt agctggctac tcagagcttc gttagccacc ggcctctacc tctcccactc
      121 ggaacgccgc cgcctctggg tctttgcccg ctgggcgggc cgggcgggat gcgccgcggg
      181 accctggtcc tggcctccgg ccgtcgccgc cgtcgcggct gagaccctcc cccaaaacct
      241 ccagtgacgc cgcagccatg gagagtggcc cgcgtgtgga gcccggcccg ggcgcacccg
      301 cagctgtgtt agccaggatc ccccaagagc caagaccgtc tccggaaggt gacccttccc
      361 ctcctccgcc gccaacaccg atgtcagcct tggttcctga cactccccca gacacacctc
      421 ctgccctgaa gactgccacg aatcctaagc agctcccact ggaaccaggg aatcccacag
      481 ggcagatctc acctcagcca gctcccccac aggaagaatg cccgtcctca gaagccaaga
      541 gcaggggccc cacccccaca gccacaggac cacgggaggc caagccttct cgaagaagca
      601 gccaaccatc ccccaccaca gtgccagcct ctgacagccc tcctgccaag caagatgtaa
      661 agaaggcagg agagagacac aagcttgcca aagagcgccg agaagagcgg gccaagtacc
      721 tggcggccaa gaaggcagtg tggttggaga aggaggaaaa agccaaggcg ctccgggaaa
      781 agcaactcca ggagcgccgc cgacggctgg aggagcagcg gcttaaagcc gaacagcgcc
      841 gggctgccct ggaggagcgg cagaggcaga agcttgagaa aaacaaggag cgctatgaag
      901 cagcaatcca gcggtcagtg aagaagacgt gggctgagat ccggcaacag cgctggtcct
      961 gggcaggggc cctgcaccac agctcccctg gacgtaagac cagtgggagc aggtgctccg
     1021 tgtcggcagt aaacctgccc aaacacgtgg actctataat caacaagcgg ctctcaaagt
     1081 cctctgccac gctctggaac tcccccagta gaaatcgcag cctgcagctg agcgcatggg
     1141 agagcagcat tgtggatcgt ctgatgacgc ccaccctctc cttcctggct cggagtcgca
     1201 gcgcggtcac actgccccgc aacggcaggg accaggccgt gccagtgtgc ccgcgctcgg
     1261 cctccgccag ccccctgacg ccttgtagcg cccctcggag cgcgcaccgc tgcaccccgt
     1321 ccggggagcg cccagagcgg cgcaagcccg gcgccggtgg cagccccgcg ctggcgcgcc
     1381 gccggctgga agccacgccg gtgcagaaaa aggagaagaa ggacaaggag cgggaaaacg
     1441 agaaggaaaa gagcgccctg gcccgcgaac ggaacctcaa gaagcgccag tcgctgccag
     1501 cgtctatcag acctcggctc tccaccggct ctgagctcag ccctaagtcc aaggcccggc
     1561 catcctctcc ctctacaacc tggcacagac ctgcctcccc ctgccccagc ccaggaccag
     1621 gacatgccct tcctccaaaa ccaccatccc cccgaggcac cactgcatca cccaaggggc
     1681 gggttcggag gaaggaggag gcaaaagaga gccccagccc gtcggggcct gaggacaaaa
     1741 accaccgcaa gagtagagcc gctgaggaga aggagccagc tgccccagcc tcaccagcgc
     1801 cctcaccggt gccctcgccc accccagccc agcctcagaa ggagcaatcc tcaacacaga
     1861 tccctgcaga aactgctgtc ccggctgtcc cagctgctcc gactgcccct cctaccgctg
     1921 ctccctcggt gacccctagc aaacccatgg cgggcaccac agaccgagag gaagccacgc
     1981 ggctcctggc tgaaaagcgg cgccaggctc gggaacagag ggaacgcgaa gaacaggagc
     2041 ggaagctgca ggctgaaagg gacaagcgaa tgcgagagga gcagctggcc cgggaggctg
     2101 aagcccgggc tgaacgtgag gccgaggcgc ggagacggga ggagcaggag gctcgagaga
     2161 aggcgcaggc tgagcaggag gagcaggagc gactgcagaa gcagaaagag gaagccgaag
     2221 cccggtcccg ggaagaagct gagcgccagc gccaggagcg ggaaaagcac tttcagaagg
     2281 aggaacagga gagacaagag cgaagaaagc ggctggagga gataatgaag aggactcgga
     2341 aatcagaagc cgccgaaacc aagaagcagg atgcaaagga gaccgcagct aacaattccg
     2401 gcccagaccc tgtgaaagct gtagagactc ggccctctgg gctacagaag gattctatgc
     2461 agaaagagga gctggccccc caggagccac agtggagcct gccaagcaag gagatgccag
     2521 ggtccctggt aaatggcctg cagcctctcc cagcgcacca ggagaacggc ttctccccaa
     2581 agggaaccgc tggggacaag agtctgggtc gcacagcaga ggggctcctc ccatttgcag
     2641 aggcagaagc cttcctcaag aaagcagtgg tgcagcctcc acaggtcaca gaagttcttt
     2701 aagcaaattg ccttggaccg aggtgcagct gtgaaggttc ctccatatca gctcgtgggt
     2761 gtctggaaga gaaagagaca gaacaaagat ggaagtggcc tggtggaccc ctgggggcag
     2821 agttcctctt tgtttttaat ccgcacctta cagactggtg atgtctttgg ctgaaagcag
     2881 gactgcccct cagtacatcc gtgtgcttac acgctcggac acccatcttc cccatacaca
     2941 acacacacac acactcatag cctctctggt cttccccctg gggaaggacc acttgtagta
     3001 tttgccttgg tttgctgggg tacagtggat gtgaatactg taaatagctt gtgctatgtg
     3061 gaagaggcgg gtagggtaca ggaggcagaa cccccctccc aagtctccct gggcagatct
     3121 tcctctattt aactgtaacc gagggggaac ccaggtctgg gaatggaggg gcacctcggg
     3181 ccacacaata ctggttgctt caggggtgat gccccctgtc ctcgcctgga atcagtgtta
     3241 ttacatctga tcaaacttct ccggaaataa agggagaaaa attctgccaa a
//
