LOCUS       XM_017321004            6162 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus mitogen-activated protein kinase kinase
            kinase kinase 4 (Map4k4), transcript variant X13, mRNA.
ACCESSION   XM_017321004
VERSION     XM_017321004.3
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000067.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Sep 21, 2020 this sequence version replaced XM_017321004.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6162
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="1"
     gene            1..6162
                     /gene="Map4k4"
                     /gene_synonym="9430080K19Rik; HGK; Nik"
                     /note="mitogen-activated protein kinase kinase kinase
                     kinase 4; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 7 mRNAs, 64 ESTs, 4096 long SRA
                     reads, 4 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 46 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:26921"
                     /db_xref="MGI:MGI:1349394"
     CDS             585..4568
                     /gene="Map4k4"
                     /gene_synonym="9430080K19Rik; HGK; Nik"
                     /codon_start=1
                     /product="mitogen-activated protein kinase kinase kinase
                     kinase 4 isoform X13"
                     /protein_id="XP_017176493.1"
                     /db_xref="GeneID:26921"
                     /db_xref="MGI:MGI:1349394"
                     /translation="MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRH
                     VKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLW
                     LVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVL
                     LTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWS
                     CGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQ
                     RPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVP
                     EQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLL
                     AERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEE
                     RRRAEEEKRRVEREQEYIRRQLEEEQRHLEILQQQLLQEQAMLLECRWREMEEHRQAE
                     RLQRQLQQEQAYLLSLQHDHRRPHAQQQPPPPQQQDRSKPSFHAPEPKPHYDPADRAR
                     EWSHLASLKNNVSPVSRSHSFSDPSPKFAHHHLRSQDPCPPSRSEGLSQSSDSKSEVP
                     EPTQKAWSRSDSDEVPPRVPVRTTSRSPVLSRRDSPLQGGGQQNSQAGQRNSTSSIEP
                     RLLWERVEKLVPRPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRVRSSSKSEGSPSPR
                     QESAAKKPDDKKEVFRPLKPAGEVDLTALAKELRAVEDVRPPHKVTDYSSSSEESGTT
                     DEEEEDVEQEGADDSTSGPEDTRAASSPNLSNGETESVKTMIVHDDVESEPAMTPSKE
                     GTLIVRQSTVDQKRASHHESNGFAGRIHLLPDLLQQSHSSSTSSTSSSPSSSQPTPTM
                     SPQTPQDKLTANETQSASSTLQKHKSSSSFTPFIDPRLLQISPSSGTTVTSVVGFSCD
                     GLRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSEILCAALWGVNLLVG
                     TESGLMLLDRSGQGKVYPLISRRRFQQMDVLEGLNVLVTISGKKDKLRVYYLSWLRNK
                     ILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKF
                     MAFKSFGELLHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIYLPTHIQCS
                     IKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIRSNQTM
                     GWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLG
                     RTSLLSW"
ORIGIN      
        1 gccccgcact tcctccggga aggccccgag ggctcccggc cccaccccgg gccgggccac
       61 catccgcgga gggccggccg cccggccatt gttcgagccc cacccctgct gaatattcac
      121 gcgggcgggc ggcgagcgag cgagggcgag ggccgggttc cgcccgctct cccggcggag
      181 ggggcggggg agtcgctcgc ccctcctcag cggcgccggt cggtgccccg cgtccccgcc
      241 cccgcccccg cctcccgcgg catctttgtc tcgcggcctc gcgctcgctc gctcgccgcg
      301 ctctccggcc ccagctccgg gccgctcgtg caggcgcgcg cgcgcggggc gccggggcct
      361 gaggcggcgg gcgacgcccg gggggcgggt gggggccgag ggaggaccgc caagccatgg
      421 tgtgagctcc gcggccagcg ctctccgcgc cgcgctccgc tccgaccgga cgacaagccg
      481 cccgggcggc ggcggcctgc ccgtgcggcc cgagccccgg cgccgccgag cccctgcccg
      541 tctctcgctc tctcgcccgc tcccggagcg gcgacccggg gaagatggcg aacgactctc
      601 ccgcgaagag cctggtggac attgacctgt cgtccctgcg ggaccctgct gggatttttg
      661 agctggtgga agtggttgga aatggcacct atggacaagt ctataagggt cgacatgtta
      721 aaacgggtca gctggccgcc atcaaggtta tggacgtcac cgaggatgaa gaggaagaaa
      781 tcaaactgga gataaatatg ctgaagaagt attctcatca tcgaaatatt gccacgtact
      841 atggtgcttt cattaagaag agccctccag gacatgatga ccaactctgg cttgttatgg
      901 agttttgtgg ggctgggtcc atcacagacc ttgtgaagaa caccaaaggg aacactctca
      961 aagaagactg gattgcttac atctccaggg aaatcctcag gggattggca catctccata
     1021 ttcaccacgt tattcaccga gatatcaagg gccaaaatgt gctgctgacc gagaatgctg
     1081 aggtgaaact tgttgatttt ggtgtaagcg ctcagctgga caggacggtt ggacggagaa
     1141 atacgttcat aggcacaccc tactggatgg ctccagaggt catcgcctgt gatgagaacc
     1201 cagacgccac ttacgactac agaagtgacc tctggtcctg tggcatcaca gccatcgaga
     1261 tggctgaagg ggccccccct ctctgtgaca tgcatccaat gagagcgctg tttctcatcc
     1321 ccagaaaccc tcctcccagg ctgaagtcaa aaaaatggtc aaagaaattt ttcagcttta
     1381 tagaaggctg tctggtgaag aattacatgc agcggccctc tacagagcaa cttttaaaac
     1441 accctttcat aagggatcag cccaatgaaa ggcaggttcg aatccagctt aaggatcaca
     1501 tagaccggac cagaaagaag agaggcgaga aagatgagac ggagtacgag tacagcggga
     1561 gcgaggagga ggaggaggaa gtgcctgagc aggagggaga gccaagttcc atcgtcaatg
     1621 tgcctggaga gtcaactctg cgacgtgatt tcctgagact gcagcaggag aacaaggagc
     1681 ggtctgaggc tctgcggaga cagcagcttc tgcaggagca gcagctccgg gagcaggagg
     1741 agtataagag gcagctgctg gctgagaggc agaagcggat tgaacagcag aaagaacaga
     1801 ggaggcggct ggaagagcaa caaagaagag aacgggaagc caggaggcag caggagcgtg
     1861 agcagcggcg gcgtgaacaa gaggagaaga ggcgtctcga ggaactggaa aggcggcgta
     1921 aagaagagga agagaggaga cgggcagaag aggagaagag gagagtggag agggaacagg
     1981 agtacatcag gcggcagcta gaggaggagc agcggcacct ggagatcctg cagcagcagc
     2041 tgctccagga gcaggccatg ttactggagt gccgatggcg ggagatggag gagcaccggc
     2101 aggcagagag gctccagagg cagttgcaac aagaacaagc atatctcctg tctctacagc
     2161 acgaccacag gaggccgcac gcacagcagc agccgccgcc cccgcagcag caggacagga
     2221 gcaaaccgag ctttcatgct ccagagccca agcctcacta tgaccctgct gacagagctc
     2281 gggagtggtc ccacctggca tctctcaaga acaatgtctc ccctgtctcg agatcccatt
     2341 ccttcagtga cccttctccc aaattcgcac accaccatct ccgctctcag gacccatgtc
     2401 caccttcccg cagtgagggg ctcagtcaga gctctgactc taagtcggag gtgcccgagc
     2461 ccacccaaaa ggcttggtct agatcagaca gtgacgaggt gcctccaagg gttcccgtga
     2521 gaacgacctc tcgttcccct gtcctctccc gtcgggattc cccactgcag ggcggtggac
     2581 agcagaatag ccaagcagga cagagaaatt ccaccagcag tattgagccc cggcttcttt
     2641 gggagagagt ggaaaagctg gtccccaggc caggcagtgg cagctcttca gggtccagca
     2701 actcaggatc ccagcctggc tcccatcctg ggtctcagag cggctccggt gaacgcttca
     2761 gagtgagatc atcatccaag tctgaaggtt ctccatcgcc acgccaggaa agtgcagcca
     2821 aaaagcctga cgataagaaa gaagtattcc ggcctctcaa gcctgcggga gaagtggact
     2881 tgactgcgtt ggccaaagag cttcgagcag tggaagatgt tcggccacct cacaaagtaa
     2941 cagactactc atcctccagt gaggagtctg ggaccacaga tgaggaggag gaggacgtgg
     3001 aacaggaggg ggctgatgat tctacctcgg gaccagaaga caccagagca gcgtcatctc
     3061 cgaacctgag caacggtgaa acagaatctg tgaaaacaat gatcgttcat gatgatgtag
     3121 aaagtgagcc agccatgacc ccgtccaagg agggcaccct catcgtccgc cagagtacag
     3181 ttgaccaaaa gcgtgccagc catcatgaga gcaatggctt tgcgggtcgc attcacctct
     3241 tgccagatct cttacagcaa agccattcct cctccacttc ctccacctct tcctccccat
     3301 cctccagcca gccgacaccc accatgtccc cacagacacc ccaggacaag ctcactgcta
     3361 atgagactca gtccgctagt agcacactcc agaaacacaa atcttcctcc tcctttacac
     3421 cttttataga ccccaggtta ctacagatct ctccatctag tgggacgaca gtgacttccg
     3481 tggtgggatt ttcctgtgat gggctgagac cagaagccat aaggcaagat cctactcgga
     3541 aaggctcagt ggtcaatgtg aaccccacga acactaggcc acagagtgat acccccgaga
     3601 ttcgtaaata caagaagaga tttaactcag agatcctgtg tgctgcctta tggggagtga
     3661 acttgctggt tggtacagag agcggtctga tgctcttgga cagaagtggc caagggaaag
     3721 tataccctct gatcagccga agacggttcc agcaaatgga tgtgctcgaa ggcctaaatg
     3781 tcctggtgac aatatctggc aaaaaggata agttacgtgt ctactattta tcctggctaa
     3841 gaaataagat tcttcataat gatccagagg ttgagaagaa gcaggggtgg accactgtgg
     3901 gcgacttgga agggtgcgtg cactataaag tcgtaaaata tgaaagaatc aagtttctgg
     3961 taattgcttt gaagagttct gtggaagtct atgcatgggc accgaagcca tatcacaaat
     4021 ttatggcctt taagtcattt ggagaactgc tacataagcc attactggtg gatctcactg
     4081 tggaggaagg ccagaggttg aaagtgatct atggatcctg tgcgggattc catgctgttg
     4141 atgtggattc aggctcagtc tatgacattt atctaccaac acatattcag tgtagcatca
     4201 aaccccatgc aatcattatc ctccccaaca cggatgggat ggagctgctg gtgtgctacg
     4261 aagacgaggg ggtttacgtt aacacgtacg gaaggatcac caaggacgtg gttctgcagt
     4321 ggggagagat gccgacatct gtagcatata tccggtcgaa tcagacaatg ggctggggag
     4381 agaaggcaat agagatacga tctgtggaaa ctggtcactt ggatggtgta tttatgcaca
     4441 aaagggctca gagactaaag ttcctgtgtg aacgcaatga caaggtgttc tttgcctccg
     4501 tccgctctgg tggcagcagc caggtctatt tcatgacctt aggcaggact tctcttctga
     4561 gctggtagag gcagtgtgag ctgggatcac tgacctctgg agtcggcaag accctgagcg
     4621 agaccttgga attccttgca actggagctc agagctgtgc tggtgcagcc aggacagctg
     4681 tctgcaggcc acctgcgcgt cgcatcgggt cgggtcgggc cctctcccct ccctcctaca
     4741 ctttttgcca gtttattccc attctctcct tttcctttct caaataaatc aaggctgcat
     4801 tgcagctggt gctgtctgga ctccaccatc ggtgctagga gtgcttggga atggactcag
     4861 accgggaaga gcgagtgagc gagcgagcgc tgcgccttcc ctgcagctcc aggaggccgt
     4921 ctccgagcga gcgagcgagc gagcgactgt cctatgggtg tctgaagggt gtgatgagcg
     4981 caccgtcaga ctttggcagt gggcacaaag aagtgaaaag tgggcgtaag aagcagcttg
     5041 cagaagcaga gaacagattt aatatagtaa cattaacaat gtatttaatt gacatttctc
     5101 tttttgtaat gtgacagtat gtggacagag aagaaggtgc aggtttaaga agttaatatt
     5161 tataaaatgt gaaagacaca gttactagga tacctttttt ttgtgggtgg ggcttagggt
     5221 ggggtggggt gggttaaagg gtcccatttt gtttctttga aagttttttg gaggggattg
     5281 tcctggccaa gaactcagtc atttttctgt gtaccaagtt ttgcctaaat tgtgcaggtg
     5341 gttcttaaaa aagaaagaaa aggaaaagaa aagtgtgtgt cttgttggag ggccagaagt
     5401 ttgtcgtgtg acagtattag cccggcctcg gctacaggtt taaagtctgt taggcctaag
     5461 tgcagctccc cgtggcctgc acacaccgta ggagaaggtc agctttcctg tggggttttg
     5521 tttcattttg ttttgttttt tgcctacctc actgttttta atgcattgag aggtgactta
     5581 gtttatggtt ttggcagaaa acattaatgt ttaatttaac cttaatacca aaactatctg
     5641 attaaagttt gactttgtca caagtctaaa tcaggtacaa aaaaggaaaa aaacaaaaaa
     5701 taaaaaacaa gcctgtctat gacagcaggg agtagccttg tagctgctgc agtctgcttc
     5761 tagcatgcag actgctctgt tctcaccaag ttcaccatta gcgggtgaca ggcagccagc
     5821 tgccacctgt gacacataag agatgtcatt gttctcagtt gggtttggaa gcaggcaggg
     5881 gtcacactgg ggagtcacac agactgttga tgttgcagga gcctttcttg ggagtgacgg
     5941 tgtgtccctt ttctaagaat gcaatgcact aaaactgttt taagaatgta gtttgcccta
     6001 cttcttcata gatggcccct ccctgcctgt gtttcaggtg taaaatcgac actctggctt
     6061 ttctcctttt ctcacgtgct ctcttgttct ctttttttaa aactaatttt tctttatgaa
     6121 tatgtctgtg acatttgtaa taaatgtctt gtaataattt gc
//
