LOCUS       XM_011249037            6106 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus mitogen-activated protein kinase kinase
            kinase 3 (Map3k3), transcript variant X2, mRNA.
ACCESSION   XM_011249037
VERSION     XM_011249037.4
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000077.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Sep 21, 2020 this sequence version replaced XM_011249037.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6106
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="11"
     gene            1..6106
                     /gene="Map3k3"
                     /gene_synonym="MAPKKK3; Mekk3; mKIAA4031"
                     /note="mitogen-activated protein kinase kinase kinase 3;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 2 mRNAs, 68 ESTs, 766 long SRA reads, 4
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 25 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:26406"
                     /db_xref="MGI:MGI:1346874"
     CDS             1800..3650
                     /gene="Map3k3"
                     /gene_synonym="MAPKKK3; Mekk3; mKIAA4031"
                     /codon_start=1
                     /product="mitogen-activated protein kinase kinase kinase 3
                     isoform X1"
                     /protein_id="XP_011247339.1"
                     /db_xref="GeneID:26406"
                     /db_xref="MGI:MGI:1346874"
                     /translation="MKDLVALQMSRRTRLSGYETMKNKDTGHPNRQSDVRIKFEHNGE
                     RRIIAFSRPVRYEDVEHKVTTVFGQPLDLHYMNNELSILLKNQDDLDKAIDILDRSSS
                     MKSLRILLLSQDRNHTSSSPHSGVSRQVRIKPSQSAGDINTIYQAPEPRSRHLSVSSQ
                     NPGRSSPPPGYVPERQQHIARQGSYTSINSEGEFIPETSEQCMLDPLSSAENSLSGSC
                     QSLDRSADSPSFRKSQMSRARSFPDNRKECSDRETQLYDKGVKGGTYPRRYHVSVHHK
                     DYNDGRRTFPRIRRHQGNLFTLVPSSRSLSTNGENMGVAVQYLDPRGRLRSADSENAL
                     TVQERNVPTKSPSAPINWRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPET
                     SKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKILTIFMEYMPGGSVKDQLKAYGA
                     LTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTIC
                     MSGTGIRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAI
                     FKIATQPTNPQLPSHISEHGRDFLRRIFVEARQRPSAEELLTHHFAQLVY"
ORIGIN      
        1 cgctgcttcg cgacgccccg ccccaggctg aggggaggag gaccctgggc cgccgcctga
       61 caaggcatgg acagttcgcc gggcccgggg ctgaggatcg cggaccgctc gcctctccgc
      121 ggtgcctcga tcggggcgcc gttctggcta cctccggggg tgccctaccg gccaaaccca
      181 ctcggcaact ctctttccgg gcatgcggcc ggcgtatccc ggggaggggt ctgcgggacc
      241 gaggcccgtc gggcggccca ctgcggtccc cagcgagctg gcgcgcgagc ttgagggtgg
      301 gggagccgga gctcagtgtg gggccggggc tggagcctgg tgcaggccca gctgctgttg
      361 tgtcttttcc ttgatttgct tttttttttt tttttttttc ctgcctgtgt catttccttc
      421 cctttgctca cacaggctgg cctgtgagtt cccggggctt tgctctggag ctctgtgcgc
      481 tctcctgcgc gggggagggg gacgcggggg gagggtatgc ggggcatcca ctgcgacgct
      541 attcgacgcg gatccctgtt agcaatagca ggcttgagaa atgcgagctg cgctcctcgc
      601 agattactgg aagttaagaa tccttgagcg ctgagggtta taactcaaac cctacttttg
      661 gaaaaacccg gcttttatat ttatcctgcg ctacccctgc aactatgtaa ctttttgaaa
      721 gaggcattcg gtacataaaa ggatcactat gaaatcattt cctttttgtc agtatttgta
      781 attctcctgt gaagatgtaa tctaagaaaa gtttttttaa tgccttctac aaaatatttg
      841 agctgtttta tatatatttt gcataatttt ggttctttat caaaaagtct tggacttagc
      901 taaggaatgt gtgacatttt aaatatattt tgcttcccca gttggggcag gtattgtgat
      961 gctcattttc ctggtctcaa tcaggttttg caaaaatatt tagtattatt ctaagtcaga
     1021 aaggggtgaa atttagtgaa agtctccttt gcagaagtat tcattgcttg tgtgagtgct
     1081 ccataagatg aaatgctaat gtttgttttg ccctaaagca aggtcaagtc atttttgtag
     1141 gaggttttgt gggtgcagta gcaaattggc cagatactcg attgtggtgg aactccttac
     1201 tctggcttta agttaattgc tttgttcttt atcagactgc ccctcataca gtatgggaag
     1261 gatttgttca tttgctgggt tttctattcc ctttccatgc tatatttcag attttttttt
     1321 ctatagaact ctcatctgag agacaccaaa ggaaactagt aaggatttac atttcaacat
     1381 ttatttattc acatgtctaa tacaatatat tccaataaat gtttatggaa tgcttattat
     1441 atggggcaca tatttcctta tatattattg gggaacagaa ttctttttat ccttccctgt
     1501 ttccccacat ttacctactg ctacagactt taagctagat ctttgaatta tggacctgta
     1561 ttgtaatagt cttatacgct ttccttcttg cccggtgtgt gagccttaag tcgcaaacgg
     1621 gagtatgaga cccttgagga tatacagacc tcacatggaa cactttggtt gtaaaaccag
     1681 tgtttcctgg ctgcatactt ggagtacagt gatcctctgc ctctgcctct taagtgtggg
     1741 catttaggca tgtgctacca catctggctc aggatgaaca agaggcatta gactcgatca
     1801 tgaaggacct ggtggccctc cagatgagcc gacgaacccg gttgtctgga tatgagacca
     1861 tgaagaataa ggacacaggt cacccaaaca ggcagagtga cgtcagaatc aagtttgaac
     1921 acaatgggga gagacgaatt atagcattca gccggcctgt gagatacgaa gatgtggagc
     1981 acaaggtgac aacagtcttt gggcagcctc ttgatttgca ttatatgaat aatgagctct
     2041 ccatcctgtt gaaaaaccaa gatgatctcg ataaagccat tgacattttg gatagaagct
     2101 caagtatgaa aagccttagg atactactgt tatcccaaga cagaaaccat actagttcct
     2161 ctccccactc tggagtgtcc aggcaggttc ggatcaagcc ttcccagtct gcaggggata
     2221 taaataccat ctaccaagct cctgagccca gaagcaggca cctgtctgtc agctcccaga
     2281 accctggccg aagctctcct cccccgggat atgtacctga gcgacaacag cacattgccc
     2341 ggcaaggatc ctatacgagc atcaacagcg aaggtgaatt catcccagag accagcgaac
     2401 agtgtatgct agatcccctc agcagtgccg aaaattcctt gtcaggaagc tgccaatcct
     2461 tggacaggtc agcagacagc ccatccttca ggaaatcaca aatgtcccga gcccggagct
     2521 tcccagacaa cagaaaggaa tgctcagatc gggagaccca gctctatgat aaaggtgtca
     2581 aaggtggaac ctatcccagg cgctaccatg tgtctgtgca tcacaaagac tacaatgatg
     2641 gcagaagaac atttccccga atacgacggc atcaaggcaa cctattcact ctggtgccct
     2701 caagtcgctc cttgagcaca aatggcgaga acatgggtgt agctgtgcaa tacctggacc
     2761 cccgtgggcg cctacggagt gcagacagtg agaatgccct cactgtgcag gaaaggaatg
     2821 tgccaaccaa atctcctagt gctcccatca attggcgtcg ggggaagctc ctgggtcaag
     2881 gtgccttcgg cagggtctac ttgtgctatg atgtggacac aggacgtgaa cttgcttcta
     2941 agcaggtcca gtttgaccca gatagtcctg agacaagcaa ggaggtgagt gctctggagt
     3001 gtgagatcca gttgctgaag aacctgcagc atgagcgcat tgtgcagtac tacggctgcc
     3061 tgcgggaccg tgctgagaag atcctcacca tctttatgga gtatatgcca gggggctctg
     3121 taaaagacca gttgaaggcc tacggagctc tgacagagag tgtgacccgc aagtacaccc
     3181 ggcagattct ggagggcatg tcatacctgc acagcaacat gattgtgcat cgggacatca
     3241 agggagccaa tatcctccga gactcagctg ggaatgtgaa gcttggggat tttggggcca
     3301 gcaaacgcct acagaccatc tgcatgtcag ggacaggcat tcgctctgtc actggcacac
     3361 cctactggat gagtcctgaa gtcatcagtg gcgagggcta tggaagaaag gcagacgtgt
     3421 ggagcctggg ctgtactgtg gtggaaatgc tgacagagaa accaccttgg gcagagtatg
     3481 aagctatggc tgccattttc aagattgcca cccagcctac caatcctcag ctgccctctc
     3541 acatctcaga acacggcagg gacttcctga ggcgcatatt tgtggaagct cgtcagagac
     3601 cctcagctga ggagctgctc acacaccact ttgcacagct agtgtactga gctctcaagg
     3661 ctatgcagct gccagctgcc acctgctgag caggcaaggg gctgctgtca ggctcagtga
     3721 agttgctgct tcttccaggc aaggctatga ccagtggagc atcggtccag ccattgtttg
     3781 tctgtgcccc atctgccact gggactcaaa gccaggatgg gatagctctg gcatcaagac
     3841 tgggagctcc agcctgtaag acccaagagc tttagcacct taagctcagt atggcgggaa
     3901 gggctggaaa cagtatgcaa gactgccatg ggtcctgcct accctcagat gtgtcctaac
     3961 actgcagaca gcactgaagt caagagggac tggggcacag gaggtcctca agggtatgaa
     4021 tagtgttact tcattcagag tgttactttg tttctctccc aatgtttgga gaccaccagc
     4081 ctgtctctgg gctgcaagcc tgaggtaaag cccagcatcc cccagccaac agaaggtaga
     4141 ggtttgggct accccactat agcttccagg tattcggtgt cagtcctgtc ttaccaaaga
     4201 tgaatgaagc aaatgttaca ctgccttatt ctgggaagga ggagctactc ggataagcag
     4261 ggcctgagag atggagctgc ctccagaaac tggggagacc cagtcttgtc aatgcaattg
     4321 tctctgtttt acaagttgga gtcactctta tgctgttccc agttttaaaa ctggagactt
     4381 tgccctctga gctctggaga cccatgtggg cttaggcctt ggactggatg gaagagctga
     4441 tggcctctgc cccctggcct gccctctgtt ccctcactgg agcagagaaa gtagacaaca
     4501 caagtcaggg cacctggttc tgggcagctc agcagagtgc agggggttgt ctcaggctgt
     4561 ctgcatctca aatctgtcag gcctgagccc actccatggg aaagtccttg agctgccaca
     4621 accgtgtcca aagccaccag ctgtgttcct cagcccgacc tgtccacttg tcatcaacct
     4681 cattcccttc ttgttcctcc cacaaaggag gatgccagta ggggctaggg aaagagttat
     4741 ctccaagcag cttagagttg gccatattta cctcagcctg ggtgctggtc ctttcttcca
     4801 gcccctttct tcccctccaa atgtgcctat ttctagagct cctccctcct aactcccaaa
     4861 tttttgggag ttatcattaa aggaaaggaa aaaaaaaaaa aagaagccag tgcccaggga
     4921 tgggcatctc cagggagctg gggattagtg ccaggcagct ctttgccagc catgcccact
     4981 tccccatggg cacagaacaa gccaaagcct tcgttgtatg ttgacgatgc acttttatga
     5041 atgtagtttc tatcgctgtt tttagccttt tcacatcatg taatgtgagg ccttgtactt
     5101 gttaatttat atctcagatc catatttgat ggttttatat atatatatca attctagact
     5161 gttaccggtg atggactcct gaagagagaa cagaaattga aagcagctgg ttttgcagat
     5221 atgtgtgttg cacggtgcca attgggcctg ggcccctctg ttttatttcc tttcccttgg
     5281 gggtctgtca ggccactctc taactgctct gaagccagtg agcaaagtcc tgcttccacc
     5341 tcagcctttg cccaaagtag ggactggccc ctcttctaga ccaaagctgc caaaaggcag
     5401 ctgggcctct ccatgacccc atcctgatgg ctatatagca ccctttagcc tatccctatc
     5461 cacaccccga acccaaagga gatagagatt ggtggggtga caagatgtta gatgagacaa
     5521 ctctgcttgt cacaggttca ggctctcacg gagctccccc catatcccca tggggggggg
     5581 gggggagtgt attacctcat aggcaatgtt tctaaaatga acttaaaagt aaaccaacaa
     5641 attctgcact ccaaaggggg ggtggggggg agacaccttt ttttgtgcca aaaactgtgg
     5701 acatgctggt tcagcagcct caggaccaag ctgttaattt atttttttct tattaacaaa
     5761 tccaaatgac aagttgtggg cctccagggt ggcctgggcc caaaggttat gaaggaaggt
     5821 ttcctagcag cccttggcct gctgtgcaaa gatgctacac caccttcatt tgttcttcat
     5881 tccatggggt ttatctgcct tcaccaaccc cacatggaag ggccaagcct gggtcaggtg
     5941 cacgctgcca ccctccttcc cctccctccc acttgcccag ctctgtgtct gaattgtgga
     6001 atgtgcagaa gaacctgcag ccatagttat tgactatatc ttgactgagg gcttgcagtg
     6061 caaagccagg ccagtgcatt acttacaata aaagggatca tttata
//
