LOCUS       XM_030250951            4409 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus mitogen-activated protein kinase kinase
            kinase 11 (Map3k11), transcript variant X1, mRNA.
ACCESSION   XM_030250951
VERSION     XM_030250951.2
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000085.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Sep 21, 2020 this sequence version replaced XM_030250951.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4409
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="19"
     gene            1..4409
                     /gene="Map3k11"
                     /gene_synonym="2610017K16Rik; Mlk3; PTK1; SPRK"
                     /note="mitogen-activated protein kinase kinase kinase 11;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 15 mRNAs, 9 ESTs, 442 long SRA reads, 20
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 47 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:26403"
                     /db_xref="MGI:MGI:1346880"
     CDS             1336..3888
                     /gene="Map3k11"
                     /gene_synonym="2610017K16Rik; Mlk3; PTK1; SPRK"
                     /codon_start=1
                     /product="mitogen-activated protein kinase kinase kinase
                     11 isoform X1"
                     /protein_id="XP_030106811.1"
                     /db_xref="GeneID:26403"
                     /db_xref="MGI:MGI:1346880"
                     /translation="MEPLKNLFLKSPLGSWNGSGSGGGGGTGGVRPEGSPKATAAYAN
                     PVWTALFDYEPNGQDELALRKGDRVEVLSRDAAISGDEGWWAGQVGGQVGIFPSNYVS
                     RGGGPPPCEVASFQELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAE
                     SVRQEARLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLSRALAGRRVPPHVLVN
                     WAVQIARGMHYLHCEALVPVIHRDLKSNNILLLQPIEGDDMEHKTLKITDFGLAREWH
                     KTTQMSAAGTYAWMAPEVIKASTFSKGSDVWSFGVLLWELLTGEVPYRGIDCLAVAYG
                     VAVNKLTLPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEALEAQVLREMPRDS
                     FHSMQEGWKREIQGLFDELRAKEKELLSREEELTRAAREQRSQAEQLRRREHLLAQWE
                     LEVFERELTLLLQQVDRERPHVRRRRGTFKRSKLRARDGGERISMPLDFKHRITVQAS
                     PGLDRRRNVFEVGAGDSPTFPRFRAIQLEPTESGQTWGRQSPRRLEDSSNGERRACWA
                     WGPSSPKPGEAQNGRRRSRMDEATWYLDSDDSSPLGSPSTPPALNGNPPRPSPEPEEP
                     RRAGPTERGNSSGTPKLIQRALLRGTALLASLGLGRDLQPPGGLSRERGESPTAPPPA
                     QMPSPCPPELPSTPLIRLSQTTPDAHSSPTPGPLLLDLGVPSGQPSAKSPRREETRGR
                     TVSPPPGISRSAPGTPGTPRSPPLGLISRPRPSPLRSRIDPWSFVSAGPRPSPLPSPQ
                     PAPRRAPWTLFPDSDPFWDSPPANPFRGGSQDCRTQTKDMGAQAPWAPEAGP"
ORIGIN      
        1 gcaagcgcgg agaagtagcg aagtgacggg atgcagaggt atcttaggcg cgcgcgcagt
       61 caaattctag agccaccaaa atatgggacg gccgggtgag tcgccattgg gtaacgactt
      121 gatgactggc gcaaagcttt tccaatgcgt tacaggaggc ggggaaaagc tggagaatgg
      181 gactcctcac ggctacttcc agtttgcgtt accgggtcac acccccgact tgggccgcct
      241 ctccttagtg cgagaccgta aatcatggtt gtcgcttggc ttacgcctct acttccgggt
      301 cagagcttag ccgaagcaga gagtgatcct gatcaggcct gagtagtcga acaggatgac
      361 ataggctttc ttaaagtaac agacacagga caagtgatga actaacgaag aggttgttga
      421 aggcccttca actctgaatc taatcccggg caaagttctg aacgacagtt tcaggttttt
      481 gcctctcggg tgaaaggaag ataattttaa atggttccaa gagcttcaag tgtaagccga
      541 ttttgaagtc ccaaacttct ctgttcacat ccccctctag cactgaaaag cagggtatct
      601 tgttatttca tatatggaaa gaacgaatct taaagagctc tgcaacttcg tagccaagac
      661 cagattttgg ttttgaggca atcacaaggg tgatttggct gatgagaatt cagacacaag
      721 gattcttctc tgtctttgca gagatccact tcgaccgtga gcagaggagc acctaacgag
      781 ggagaagagc ggaaaaaagt gaaactccac cctccacctc tgcctcccgc ccccggggcc
      841 aaagtacaaa gggaggagga agaagggacc ggggtcggag ctgtcggggc ccaaggcact
      901 agcccaagaa gaggtagctt cggctcaact ggggactttc tcttacctct tgtgcctgga
      961 gacaacaacc agagtccggg cgctgaccct ggcaggcccc accttacggt aggcgggcgc
     1021 tgaagccagg ttcccaggac tacttcggaa ctgagggact ctgctgctcc aattcagcca
     1081 tggtgaggcg ccggaggcca gtgggcccca cccctccagc ctgaccacac tgcccttggt
     1141 gccctcctcc aaaagcccga gatgcggggg gccgggaggc gacactcctg gctccccaga
     1201 gaggcgtggg tctggggctg agggccaggg cccggatgcc caggttccgg ctctagggcc
     1261 tcacaagcca gcgggggtgg ataccacggg cacccgaaga aggtccccca cacattccaa
     1321 cgccggctcc ctgccatgga gcccttgaag aacctcttcc tcaagagccc gctggggtca
     1381 tggaacggca gtggcagtgg gggcggcggg ggtaccggtg gagtccggcc ggaggggtct
     1441 ccgaaggcaa cagcagctta tgccaatcct gtctggacag ccctgttcga ctatgagccc
     1501 aatgggcagg acgaactagc cctgaggaag ggcgaccgtg tggaggtgct gtccagggat
     1561 gcagccatct caggagatga gggctggtgg gcgggccagg tgggtggcca ggtgggcatt
     1621 tttccatcca actatgtatc tcggggtgga ggcccacccc cctgtgaggt ggccagcttc
     1681 caggagctgc gactggagga ggtgatcggc atcggtggct tcggcaaggt ctaccgtggc
     1741 agctggcgag gggagctggt ggctgtgaag gcagcccgac aggaccctga tgaggacatc
     1801 agtgtaacag ctgagagtgt tcgacaggag gcccggcttt ttgccatgct ggcccatccc
     1861 aacatcattg ccctcaaagc tgtgtgcctg gaggagccaa acctatgcct ggtgatggag
     1921 tatgcagctg gtgggcctct tagccgggcc ctggctggtc ggcgtgtgcc cccccatgtg
     1981 ctggtcaact gggctgtgca gattgcccga ggaatgcact acctgcactg tgaggctctg
     2041 gtgcctgtga tacaccgaga cctgaagtcc aacaacattc tgttgctgca gcccatcgag
     2101 ggtgacgaca tggaacacaa gaccctaaag attactgact tcggcctcgc ccgagagtgg
     2161 cacaaaacca cccagatgag tgctgcgggc acctacgctt ggatggctcc cgaggttatc
     2221 aaggcctcca ccttctccaa gggcagcgac gtctggagct ttggagtgct gctgtgggaa
     2281 ctgctgactg gggaggtgcc ctaccgtggc atcgactgtc ttgccgtagc ctatggtgtg
     2341 gctgtaaaca agttaacgtt acccatccca tctacctgcc ctgagccctt tgcacaactc
     2401 atggctgact gctgggcaca ggacccccac cgcaggcccg acttcgcctc catcctgcag
     2461 cagttggaag ctctagaagc gcaggtgctg cgggagatgc cacgggactc cttccattcc
     2521 atgcaggaag gctggaaacg cgagatccag ggcctgtttg atgagctgcg ggccaaggaa
     2581 aaggaactac tgagccggga ggaggaactg acgcgcgctg cacgtgagca gcggtcccag
     2641 gcggagcagc tgcgacggcg cgagcacctg ctggcgcagt gggagctgga ggtgttcgag
     2701 cgcgagctga cgctgctact gcagcaggtg gaccgagaac ggccgcacgt gcgccgccgc
     2761 cggggcacct tcaagcggag caaactccga gcaagggacg gcggagaacg catcagcatg
     2821 cccctggatt tcaaacaccg catcacagtg caagcctctc ctggcctgga tcggaggaga
     2881 aacgtgttcg aggttggggc tggggactcg cccaccttcc ctagattccg agccatccag
     2941 ttggaaccta cagaatcagg ccagacttgg ggtcgccagt cccccagacg tcttgaagat
     3001 tcaagcaatg gagagaggcg tgcttgctgg gcctggggtc ccagctcccc caagcctggg
     3061 gaggcccaga acgggaggag acggtcccgc atggatgaag ccacgtggta cctagattca
     3121 gacgactcgt ccccattagg gtcccctagt actcccccgg cactcaacgg taatcctcca
     3181 aggcctagcc ccgagccaga ggagccacgg agggccgggc ccacggagcg aggcaatagc
     3241 tctgggacgc ctaaactgat ccaacgtgca ttgctacggg ggaccgctct gctggcttcc
     3301 ctaggccttg gccgagatct gcaacctcca ggaggcctga gccgtgaacg cggggagtcc
     3361 ccgacagcac caccccctgc acagatgccc tcaccctgcc cacctgagct gccctccacc
     3421 ccgctcatcc gcctctcaca aacaacacct gatgcccata gttcacccac tcctggaccc
     3481 ttattgctag acctaggtgt tccctctggc cagccatcag ccaagagccc tcgacgggaa
     3541 gagacacgtg ggagaaccgt ctcaccccca ccaggaatat cacgctctgc tcctggcaca
     3601 cctggaaccc ctcgctcacc accgttgggc ctaatcagcc gacctcggcc ctcaccactc
     3661 cgtagccgta ttgacccatg gagcttcgtg tcagctgggc cacggccttc acccctgccc
     3721 tctccacagc ctgcaccccg acgggcaccg tggaccttat tcccagactc agatcccttc
     3781 tgggactccc cacctgccaa ccccttccgg ggaggctccc aggactgcag gacgcagacc
     3841 aaagacatgg gtgcccaggc cccatgggca ccagaagcag ggccctgagt gggccagacc
     3901 acaccccacg cttcggctgc cttcgaggag gcatagcata cactggaaga ggaaccagga
     3961 ggcctctgtg gctgccttgg tttcccccag ggactctgac cctttggggg tcaggaacac
     4021 tacactgcac agaaagcctt cacactggat gggggctaca ccccacatgc ctacaaactg
     4081 tagggacccc tgacttactg ccccactggg gcctgacact gtacctagct ggttaggagg
     4141 accagagcct gtctcaggga attgccccca ggagcggagc agggagcagg gaggtccagg
     4201 ggaaaggggc tgacctcagg tgtcaccagc acttttgacc aagtcctgtt actgtggccc
     4261 ctgtctccaa ggctgagttc ctggaccccc aaccctggaa gttattggag ccggggctct
     4321 ctgggtgcct ttctactgcc ccgccaaggt tggagccttg gcttggggag ccaatgaagc
     4381 caaataaact tgtaagctgt ctccccaaa
//
