LOCUS       NM_025735               1063 bp    mRNA    linear   ROD 24-OCT-2024
DEFINITION  Mus musculus microtubule-associated protein 1 light chain 3 alpha
            (Map1lc3a), transcript variant 1, mRNA.
ACCESSION   NM_025735
VERSION     NM_025735.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1063)
  AUTHORS   Dong,M.Z., Ouyang,Y.C., Gao,S.C., Gu,L.J., Guo,J.N., Sun,S.M.,
            Wang,Z.B. and Sun,Q.Y.
  TITLE     Protein phosphatase 4 maintains the survival of primordial
            follicles by regulating autophagy in oocytes
  JOURNAL   Cell Death Dis 15 (9), 658 (2024)
   PUBMED   39245708
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1063)
  AUTHORS   Jahanian,S., Pareja-Cajiao,M., Gransee,H.M., Sieck,G.C. and
            Mantilla,C.B.
  TITLE     Autophagy markers LC3 and p62 in aging lumbar motor neurons
  JOURNAL   Exp Gerontol 194, 112483 (2024)
   PUBMED   38885913
  REMARK    GeneRIF: Autophagy markers LC3 and p62 in aging lumbar motor
            neurons.
REFERENCE   3  (bases 1 to 1063)
  AUTHORS   Luan,J., Zhang,Z., Wang,Q., Li,C., Zhang,H., Zhang,Y., Peng,X.,
            Zhao,G. and Lin,J.
  TITLE     The Role of LC3-Associated Phagocytosis Inhibits the Inflammatory
            Response in Aspergillus fumigatus Keratitis
  JOURNAL   Invest Ophthalmol Vis Sci 65 (8), 4 (2024)
   PUBMED   38953845
  REMARK    GeneRIF: The Role of LC3-Associated Phagocytosis Inhibits the
            Inflammatory Response in Aspergillus fumigatus Keratitis.
REFERENCE   4  (bases 1 to 1063)
  AUTHORS   Zhang,D., Deng,W., Jiang,T., Zhao,Y., Bai,D., Tian,Y., Kong,S.,
            Zhang,L., Wang,H., Gao,S. and Lu,Z.
  TITLE     Maternal Ezh1/2 deficiency impairs the function of mitochondria in
            mouse oocytes and early embryos
  JOURNAL   J Cell Physiol 239 (6), e31244 (2024)
   PUBMED   38529784
REFERENCE   5  (bases 1 to 1063)
  AUTHORS   Liu,B., Hua,D., Shen,L., Li,T., Tao,Z., Fu,C., Tang,Z., Yang,J.,
            Zhang,L., Nie,A., Jiang,Y., Wang,J., Li,Y., Gu,Y. and Ning,G.
  TITLE     NPC1 is required for postnatal islet beta cell differentiation by
            maintaining mitochondria turnover
  JOURNAL   Theranostics 14 (5), 2058-2074 (2024)
   PUBMED   38505613
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1063)
  AUTHORS   Ropolo,A., Grasso,D., Pardo,R., Sacchetti,M.L., Archange,C., Lo
            Re,A., Seux,M., Nowak,J., Gonzalez,C.D., Iovanna,J.L. and
            Vaccaro,M.I.
  TITLE     The pancreatitis-induced vacuole membrane protein 1 triggers
            autophagy in mammalian cells
  JOURNAL   J Biol Chem 282 (51), 37124-37133 (2007)
   PUBMED   17940279
REFERENCE   7  (bases 1 to 1063)
  AUTHORS   Fimia,G.M., Stoykova,A., Romagnoli,A., Giunta,L., Di Bartolomeo,S.,
            Nardacci,R., Corazzari,M., Fuoco,C., Ucar,A., Schwartz,P.,
            Gruss,P., Piacentini,M., Chowdhury,K. and Cecconi,F.
  TITLE     Ambra1 regulates autophagy and development of the nervous system
  JOURNAL   Nature 447 (7148), 1121-1125 (2007)
   PUBMED   17589504
REFERENCE   8  (bases 1 to 1063)
  AUTHORS   Yamada,T., Carson,A.R., Caniggia,I., Umebayashi,K., Yoshimori,T.,
            Nakabayashi,K. and Scherer,S.W.
  TITLE     Endothelial nitric-oxide synthase antisense (NOS3AS) gene encodes
            an autophagy-related protein (APG9-like2) highly expressed in
            trophoblast
  JOURNAL   J Biol Chem 280 (18), 18283-18290 (2005)
   PUBMED   15755735
REFERENCE   9  (bases 1 to 1063)
  AUTHORS   Hemelaar,J., Lelyveld,V.S., Kessler,B.M. and Ploegh,H.L.
  TITLE     A single protease, Apg4B, is specific for the autophagy-related
            ubiquitin-like proteins GATE-16, MAP1-LC3, GABARAP, and Apg8L
  JOURNAL   J Biol Chem 278 (51), 51841-51850 (2003)
   PUBMED   14530254
REFERENCE   10 (bases 1 to 1063)
  AUTHORS   Suzuki,H., Fukunishi,Y., Kagawa,I., Saito,R., Oda,H., Endo,T.,
            Kondo,S., Bono,H., Okazaki,Y. and Hayashizaki,Y.
  TITLE     Protein-protein interaction panel using mouse full-length cDNAs
  JOURNAL   Genome Res 11 (10), 1758-1765 (2001)
   PUBMED   11591653
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CA322683.1, AK003122.1 and BE993199.1.
            
            On Feb 22, 2012 this sequence version replaced NM_025735.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and is the protein-coding transcript.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BI652769.1, BY703975.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-609               CA322683.1         70-678
            610-1043            AK003122.1         521-954
            1044-1063           BE993199.1         1-20                c
FEATURES             Location/Qualifiers
     source          1..1063
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 77.18 cM"
     gene            1..1063
                     /gene="Map1lc3a"
                     /gene_synonym="1010001H21Rik; 4922501H04Rik; LC3; LC3a"
                     /note="microtubule-associated protein 1 light chain 3
                     alpha"
                     /db_xref="GeneID:66734"
                     /db_xref="MGI:MGI:1915661"
     exon            1..283
                     /gene="Map1lc3a"
                     /gene_synonym="1010001H21Rik; 4922501H04Rik; LC3; LC3a"
                     /inference="alignment:Splign:2.1.0"
     exon            284..339
                     /gene="Map1lc3a"
                     /gene_synonym="1010001H21Rik; 4922501H04Rik; LC3; LC3a"
                     /inference="alignment:Splign:2.1.0"
     exon            340..446
                     /gene="Map1lc3a"
                     /gene_synonym="1010001H21Rik; 4922501H04Rik; LC3; LC3a"
                     /inference="alignment:Splign:2.1.0"
     exon            447..1045
                     /gene="Map1lc3a"
                     /gene_synonym="1010001H21Rik; 4922501H04Rik; LC3; LC3a"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1018..1023
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Map1lc3a"
                     /gene_synonym="1010001H21Rik; 4922501H04Rik; LC3; LC3a"
                     /note="hexamer: AATAAA"
     polyA_site      1044
                     /gene="Map1lc3a"
                     /gene_synonym="1010001H21Rik; 4922501H04Rik; LC3; LC3a"
                     /note="major polyA site"
ORIGIN      
        1 aggtccaggc aggcgggttt tccgtcggcc caatgggagc ggcgcgccgg cctccccttt
       61 aaggaatgtt gtgacctgac gtcacccagg cgagttacct cccgcagccg ccaccgccag
      121 gctcagcgcg agccccgcag cccttgagct cgagccccgg agcccccggc gcgccgaacc
      181 gcagacgcat ctctgagccg cgcaccccgg agccccggct gcgcgccccg ccgggcccgc
      241 gcgatgccct ccgaccggcc tttcaagcag cggcgcagct tcgccgaccg ctgtaaggag
      301 gtgcagcaga tccgcgacca gcaccccagt aagatcccgg tgatcatcga gcgctacaag
      361 ggtgagaagc agctgcctgt cctggataag accaagtttc tggtcccaga ccatgttaac
      421 atgagcgagt tggtcaagat catccggcgc cgcctgcaac tcaaccccac gcaggccttc
      481 ttcctgctgg tcaaccagca cagcatggtg agcgtctcca cacccatcgc tgacatctat
      541 gaacaggaga aggatgaaga cggattcctc tacatggtct acgcctccca agaaaccttc
      601 ggcttctgag tcaagaggag gggagggggg tggctgggag ttctggtcag gttctcccca
      661 gggaggtcct ggctcctaaa ctaagctatt tcagtcccca gtggattagg cagagatgtg
      721 acacccactc ccccccccag gtaggggcca ccagccagcc taccacatcc tgggtaggtc
      781 ctgggccagt catgttcggg ttgctctttt gggtgctggc tgggttggga gtgggtgggg
      841 agcagcatcc ctgctctgtg gggtttgtca ttttgttagg cccttgcctg tctgcccatc
      901 ttgcccctca tccacctgag gctttgcctc ctgccaggac ctgccccacc cctgaaaggc
      961 tggctcccct tgtcctgact cggtgtatgg atctgtggtc atttcctctg cagaaagaat
     1021 aaagactgct caggcctgcc tggccaaaaa aaaaaaaaaa aaa
//
