LOCUS       NM_001007573            2727 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus mannosidase, endo-alpha-like (Maneal), mRNA.
ACCESSION   NM_001007573 XM_112294
VERSION     NM_001007573.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2727)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2727)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL606933.4.
            
            [WARNING] On Jul 9, 2024 this sequence was replaced by
            NM_001007573.4.
            
            On Sep 13, 2016 this sequence version replaced NM_001007573.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7652917.349315.1,
                                           SRR7345562.2945373.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-539               AL606933.4         101540-102078       c
            540-649             AL606933.4         100271-100380       c
            650-726             AL606933.4         99038-99114         c
            727-2727            AL606933.4         95146-97146         c
FEATURES             Location/Qualifiers
     source          1..2727
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 57.92 cM"
     gene            1..2727
                     /gene="Maneal"
                     /gene_synonym="Gm50"
                     /note="mannosidase, endo-alpha-like"
                     /db_xref="GeneID:215090"
                     /db_xref="MGI:MGI:2684896"
     exon            1..539
                     /gene="Maneal"
                     /gene_synonym="Gm50"
                     /inference="alignment:Splign:2.1.0"
     exon            540..649
                     /gene="Maneal"
                     /gene_synonym="Gm50"
                     /inference="alignment:Splign:2.1.0"
     exon            650..726
                     /gene="Maneal"
                     /gene_synonym="Gm50"
                     /inference="alignment:Splign:2.1.0"
     exon            727..2727
                     /gene="Maneal"
                     /gene_synonym="Gm50"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2707..2712
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Maneal"
                     /gene_synonym="Gm50"
                     /note="hexamer: AATAAA"
     polyA_site      2712
                     /gene="Maneal"
                     /gene_synonym="Gm50"
     polyA_site      2727
                     /gene="Maneal"
                     /gene_synonym="Gm50"
                     /note="major polyA site"
ORIGIN      
        1 agccatggcc cggcggcggc gccgcgcctg catcgccctc ttcctggtgc tgctcttcgc
       61 cttcggcacg ctcatggggc tgcgcacgct caaggccccg gacgggctgc cggcgctggg
      121 cccaggcccg gaactagcac cgttcgagag gcgtcccgag gggaaccccg cgcccgcccg
      181 cgccccggct gcccccgccg cgccgccgcc gcccccgccg cgcaccgccg ccccgcgcgc
      241 ctcgctgggc ccggccgagg ccgatcctgc gcccaggcag agcctgcgcg tctactccga
      301 tctgcatgct ttttactatt cgtggtacgg gagcccgcgg cgcgagggcc actatatcca
      361 ctgggaccat gtcatggtgc cgcactggga ccccaagatc tcggccagtt acccgcgtgg
      421 ccgccacagc cctccagatg acttgggctc cagcttctac ccggagctgg ggccttacag
      481 ctcgcgggac cccgacgtgc tacgagagca catgacccag ctcaaagaag ctgccattgg
      541 agttttggtt ctctcctggt atccacctgg catggctgat gataatggag aacccacaga
      601 tgacctggta cctgccattc tggacactgc ccatcagtac aacatccagg tggccttcca
      661 tatccaaccc tacaagggcc gggatgacat cactgtccac gacaacatca agtacatcat
      721 tgacacgtat ggctcccacg gtgcattcta ccgttacaag aatagcatgg gcaagagcct
      781 cccactcttt tatatctacg actcctatct gacatcccct gaggcctggg cccacctcct
      841 gacacaaaat gggcctcact ctatccgcaa cactccctat gatggggtct tcatagctct
      901 gctcgtggag gagagccaca cccacgacat cctcgcggca ggattcgacg gaatgtacac
      961 ctactttgcc tccaatggct tctcctttgg ctcttcccat cagaactgga aagctgtgaa
     1021 gaacttctgt gataccaaca acctgatgtt catccctagc gtggggcctg ggtacattga
     1081 taccagcatc cggccctgga acaaccacaa tactcggaac cgggtcaatg gcaagtacta
     1141 tgagacagcc ctgcaggcag ccctgactgt gaggcccgag atagtctcta tcacctcctt
     1201 caatgagtgg cacgagggca cacagattga gaaagctgtc cccaagacga cgccaactcg
     1261 cctgtatctg gactacctgc ctcaccagtc cagcctgtat ttagagctga cccgccgctg
     1321 ggcagagcac ttcatcaagg aaaaggagca atggctgatg tgagggactc tcacgcaaac
     1381 aaaccttaac agatcaccaa actggttcag ttggggatat aggcactcgc tagtcccaag
     1441 tagcaactgg gagctcgtgg gtggaccagc tggctcatgc agaacagagc ctggcacctg
     1501 gactggcggt gctgggaagc aagacatgat gaagcaggag ggggcaagtg gctgcaatgg
     1561 cttaaggaac ctccaggtcc ctcagctttc agctgaggca ggtagttgta tggagttgcg
     1621 caagccgcca tgcttaggag ggtctcaggg ttctaagcta gcatgcacct tacttccctt
     1681 ggacagccac cttcccacat cttgctgaac acagggaacc acatctgaca cttctaagag
     1741 gactttaagg tccttccagt agactcctgt gccccattat caggaacact gagcacccat
     1801 actaagcacc tattgcctgt caggtgctgg ggaatttgag caaggtttcc ttcccaaagc
     1861 ttacaggatc ctgcttttgg tataactgta gctagcacct cggctgtttt cgctctttgc
     1921 agctacaccc aggcctggga gttcagctat tttttcctcc aagataatac ctctgtgacc
     1981 cggagccttt cccagatgaa cgtttagctg cagagaggac taggtcactc cttttagctg
     2041 cctaggccgg ggaggccact cactagggcc actttcagtg ctactgtgat ttgtattaag
     2101 tatgaaatgg tgtatgccag tacacattcc tcttccagtt ctcctaagtg ctgaccacta
     2161 ggtcagtctg ggacacatca gtgtatggct aggctggcta gctttagcac agtggagatg
     2221 gatctgctta taagactagt ttacataaga tttctaggga gttaacgagc cagtgcttac
     2281 tcacaaataa actaatgcta cttgcaagga tccttggtaa agtaaaacct gatgaatatt
     2341 ttcagcaaga ttcttgaaaa ggaaatgttc actagaccct tctggactgg tttacaggct
     2401 aaagctgagc ctttaactct gggaaatggc tgcagatgga ggaggtgaaa tactggtcac
     2461 tgcaaggaca accagcccag tcaccgacac ttaacccccg agacagatca gctgggctga
     2521 ccacccagct tgcagcttag ttgaaagggc tggatttaac cctgcatata tattgtggat
     2581 acagcaaggc agcaggaagg agcaagcacc ctcagatttt ctgaagacta atctacatca
     2641 acagccataa tgcacacata tatcttgact gagaaatcct actctaagga aataactcaa
     2701 aagaaaaata aaccatttac aactgtt
//
