LOCUS       NM_172418               2179 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus MEF2 activating motif and SAP domain containing
            transcriptional regulator (Mamstr), mRNA.
ACCESSION   NM_172418 NM_001146703 XM_001476117 XM_001476874
VERSION     NM_172418.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2179)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2179)
  AUTHORS   Yanay,N., Elbaz,M., Konikov-Rozenman,J., Elgavish,S., Nevo,Y.,
            Fellig,Y., Rabie,M., Mitrani-Rosenbaum,S. and Nevo,Y.
  TITLE     Pax7, Pax3 and Mamstr genes are involved in skeletal muscle
            impaired regeneration of dy2J/dy2J mouse model of Lama2-CMD
  JOURNAL   Hum Mol Genet 28 (20), 3369-3390 (2019)
   PUBMED   31348492
  REMARK    GeneRIF: Pax7, Pax3 and Mamstr genes are involved in skeletal
            muscle impaired regeneration of dy2J/dy2J mouse model of Lama2-CMD
REFERENCE   3  (bases 1 to 2179)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2179)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   5  (bases 1 to 2179)
  AUTHORS   Mokalled,M.H., Johnson,A.N., Creemers,E.E. and Olson,E.N.
  TITLE     MASTR directs MyoD-dependent satellite cell differentiation during
            skeletal muscle regeneration
  JOURNAL   Genes Dev 26 (2), 190-202 (2012)
   PUBMED   22279050
REFERENCE   6  (bases 1 to 2179)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   7  (bases 1 to 2179)
  AUTHORS   Meadows,S.M., Warkman,A.S., Salanga,M.C., Small,E.M. and Krieg,P.A.
  TITLE     The myocardin-related transcription factor, MASTR, cooperates with
            MyoD to activate skeletal muscle gene expression
  JOURNAL   Proc Natl Acad Sci U S A 105 (5), 1545-1550 (2008)
   PUBMED   18230740
REFERENCE   8  (bases 1 to 2179)
  AUTHORS   Creemers,E.E., Sutherland,L.B., Oh,J., Barbosa,A.C. and Olson,E.N.
  TITLE     Coactivation of MEF2 by the SAP domain proteins myocardin and MASTR
  JOURNAL   Mol Cell 23 (1), 83-96 (2006)
   PUBMED   16818234
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY717195.1, BY137380.1, BY145171.1 and AC149057.7.
            
            On or before Apr 8, 2010 this sequence version replaced
            NM_001146703.1, NM_172418.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DQ534901.1, SRR12282455.9374266.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-157               BY717195.1         2-158
            158-187             BY137380.1         159-188
            188-199             BY717195.1         189-200
            200-535             BY145171.1         3-338
            536-553             AC149057.7         25853-25870         c
            554-641             AC149057.7         25458-25545         c
            642-836             AC149057.7         25091-25285         c
            837-1061            AC149057.7         24354-24578         c
            1062-1116           AC149057.7         24209-24263         c
            1117-2179           AC149057.7         23014-24076         c
FEATURES             Location/Qualifiers
     source          1..2179
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 29.4 cM"
     gene            1..2179
                     /gene="Mamstr"
                     /gene_synonym="2810022D01Rik; 5430432N15Rik; Mastr"
                     /note="MEF2 activating motif and SAP domain containing
                     transcriptional regulator"
                     /db_xref="GeneID:74490"
                     /db_xref="MGI:MGI:1921740"
     exon            1..54
                     /gene="Mamstr"
                     /gene_synonym="2810022D01Rik; 5430432N15Rik; Mastr"
                     /inference="alignment:Splign:2.1.0"
     exon            55..192
                     /gene="Mamstr"
                     /gene_synonym="2810022D01Rik; 5430432N15Rik; Mastr"
                     /inference="alignment:Splign:2.1.0"
     CDS             135..1400
                     /gene="Mamstr"
                     /gene_synonym="2810022D01Rik; 5430432N15Rik; Mastr"
                     /note="MEF2-activating SAP transcriptional regulatory
                     protein"
                     /codon_start=1
                     /product="MEF2-activating motif and SAP domain-containing
                     transcriptional regulator"
                     /protein_id="NP_766006.2"
                     /db_xref="CCDS:CCDS21257.2"
                     /db_xref="GeneID:74490"
                     /db_xref="MGI:MGI:1921740"
                     /translation="MTLAASSQRSQIIRSKFRSVLQLRIHRRNQDCTSDSDPWISASG
                     PALAPALPTVPASFLVSPGVLSPEPAYCPWRAPKKESPKNSQHWKEPKVRGNLTYHLY
                     MPPEQRQGPRANLQVERSTLGPPDPPLWEKNSQRPHPRMKPSSAGVSSPSPPSHKLEL
                     QTLKLEELTVSELRQQLRLRGLPVSGTKAMLLERMRGGTPPRERPKPRREDKEAAAPW
                     PRLKPKALGTTRLPSTVKASATNRRLKFSGATDPLGAAPAPASVPAPTPSPALAPTPT
                     PAPVPAPAPAPFPTPPASLTLEEELQEAIRRAQLLPNRNIDDILEDQVEPDDLLPPVP
                     LDFPGSFDLLSPSPDSEGFSSVFSSSLPSPTSSLSPSPRALTDSLDWLEALSGGPPLG
                     SGPPGPSIFSADLSDPSGSLLWELLPDPW"
     exon            193..231
                     /gene="Mamstr"
                     /gene_synonym="2810022D01Rik; 5430432N15Rik; Mastr"
                     /inference="alignment:Splign:2.1.0"
     exon            232..371
                     /gene="Mamstr"
                     /gene_synonym="2810022D01Rik; 5430432N15Rik; Mastr"
                     /inference="alignment:Splign:2.1.0"
     exon            372..553
                     /gene="Mamstr"
                     /gene_synonym="2810022D01Rik; 5430432N15Rik; Mastr"
                     /inference="alignment:Splign:2.1.0"
     exon            554..641
                     /gene="Mamstr"
                     /gene_synonym="2810022D01Rik; 5430432N15Rik; Mastr"
                     /inference="alignment:Splign:2.1.0"
     exon            642..836
                     /gene="Mamstr"
                     /gene_synonym="2810022D01Rik; 5430432N15Rik; Mastr"
                     /inference="alignment:Splign:2.1.0"
     exon            837..1061
                     /gene="Mamstr"
                     /gene_synonym="2810022D01Rik; 5430432N15Rik; Mastr"
                     /inference="alignment:Splign:2.1.0"
     exon            1062..1116
                     /gene="Mamstr"
                     /gene_synonym="2810022D01Rik; 5430432N15Rik; Mastr"
                     /inference="alignment:Splign:2.1.0"
     exon            1117..2179
                     /gene="Mamstr"
                     /gene_synonym="2810022D01Rik; 5430432N15Rik; Mastr"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1978..1983
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mamstr"
                     /gene_synonym="2810022D01Rik; 5430432N15Rik; Mastr"
                     /note="hexamer: ATTACA"
     polyA_site      1997
                     /gene="Mamstr"
                     /gene_synonym="2810022D01Rik; 5430432N15Rik; Mastr"
                     /note="major polyA site"
ORIGIN      
        1 gggagactcc acccgcttca aggcacagct gagtagctga gaggagccta cctgcctccc
       61 gtcatccact ttgaccctgc cgcgctctgg tggctctggc ttcctctgtc caggtctcca
      121 cctcagcctt ggcaatgacc ctggcagcct cctcccagcg ctcccaaatc atccgttcca
      181 agttccgctc tgtcctgcag cttcggatcc acagacggaa tcaagactgc acctctgatt
      241 cagatccatg gatctcagcc tcaggcccag ctctggctcc agctttgccc actgttcctg
      301 cctctttcct tgtcagccct ggcgtcttgt cccctgagcc agcatattgt ccttggaggg
      361 ctccaaagaa ggaatctccc aagaactccc aacattggaa ggagcctaag gtcaggggga
      421 acttgacata tcacctgtac atgcctccag aacagagaca agggcccagg gcaaatctgc
      481 aagttgagag gtcaaccctg ggtcccccgg acccacctct ttgggaaaag aattcacaga
      541 gaccacatcc tcggatgaag ccttcctcag caggagtctc cagtccctcg cccccttcac
      601 acaagctgga acttcagacc cttaaactgg aagagctgac ggtctcagag cttaggcagc
      661 agctgcgcct gcggggactc ccggtgtccg ggaccaaagc gatgctcctg gagcgcatgc
      721 gtggtggcac cccgcccaga gaacggccga agcccaggcg agaggacaaa gaggccgctg
      781 ctccctggcc ccgcctcaag cccaaggcgc tgggaactac tcggctaccc agcacggtga
      841 aggcaagcgc gacaaatcgt aggctgaagt tttctggagc tacggatccc ctgggagcag
      901 ctcccgctcc ggcttctgtt cctgctccca ctccctctcc agctttggct ccgactccga
      961 ctccagctcc agttccagct ccagctccag ctcctttccc gacacctcca gctagcctga
     1021 ctctggagga ggagctgcag gaagcgatcc gtagggcgca gctgcttcca aaccgcaaca
     1081 tcgatgacat cctggaagac caagtggagc cagatgacct gctgcctccc gtgcccttgg
     1141 acttccctgg ctcatttgac ctgctgtctc cctccccgga ctcggaaggc ttctcttccg
     1201 tcttctcttc ttcactaccg tcccccacaa gctccctgtc cccttctcca agggccctca
     1261 ctgattcctt ggactggctg gaggccttga gtgggggtcc accactgggc tctgggcctc
     1321 ccggccccag catcttctct gcggacctat ctgatcccag tggcagtctg ctctgggaac
     1381 tgctgccaga tccttggtga cagacccttg ggtctaagga gaggtcatct gcatccacag
     1441 ggaccctcca actacagagt actgatgccc tcgtcccctc ctgactcacc gctgctgctg
     1501 atatcttatg tgcctggacc tgcctatggg gcctctgtat ggcccctccc aggcccagtg
     1561 gttggggttg gggggttcat ttgctactgg ccagtgcata caagcttgct gcctccctca
     1621 gagacctgca ggttgtgtgg ctgcctgtca tctggggatg tgaaactttg tgctgtttga
     1681 ggtcaggaaa ggaccaggta agagtagaag gaccgccccc cacccccacc ccgtgggccc
     1741 ccaagttcta gttagaggtg agaggaccag aagctactag tgagaggtga ctacaaactc
     1801 cctatgacct tgaacttatg gccccacccc cacctcagag ctgtgatttt atctagcttt
     1861 cttggggttt tgttttgttt tgttttgttt tgtttttgag agcaagtgtt gctatgtagt
     1921 gccaagctgg cctcaaactt gttacaatcc tcctgcttca tcctcctggg tgctgagatt
     1981 acagacatga gccattatac ccagttctca tgtcttattg aagggcttcc cagagccatg
     2041 aggtgggaag atagataaaa ggggagagga gatagaatgt ttcccggggg agcctctgcc
     2101 tccacctcgc gctggaagga tgactgtcta gtgaattaaa ctgtggatct cgcgtgtggc
     2161 ccgaggctca tgagactgg
//
