LOCUS       NM_001004176            6499 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus mastermind like transcriptional coactivator 3 (Maml3),
            mRNA.
ACCESSION   NM_001004176 XM_485233
VERSION     NM_001004176.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6499)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6499)
  AUTHORS   Lewandowski,J.P., Du,F., Zhang,S., Powell,M.B., Falkenstein,K.N.,
            Ji,H. and Vokes,S.A.
  TITLE     Spatiotemporal regulation of GLI target genes in the mammalian limb
            bud
  JOURNAL   Dev Biol 406 (1), 92-103 (2015)
   PUBMED   26238476
REFERENCE   3  (bases 1 to 6499)
  AUTHORS   Moayedi,Y., Basch,M.L., Pacheco,N.L., Gao,S.S., Wang,R.,
            Harrison,W., Xiao,N., Oghalai,J.S., Overbeek,P.A., Mardon,G. and
            Groves,A.K.
  TITLE     The candidate splicing factor Sfswap regulates growth and
            patterning of inner ear sensory organs
  JOURNAL   PLoS Genet 10 (1), e1004055 (2014)
   PUBMED   24391519
REFERENCE   4  (bases 1 to 6499)
  AUTHORS   Wiese,C.B., Ireland,S., Fleming,N.L., Yu,J., Valerius,M.T.,
            Georgas,K., Chiu,H.S., Brennan,J., Armstrong,J., Little,M.H.,
            McMahon,A.P. and Southard-Smith,E.M.
  TITLE     A genome-wide screen to identify transcription factors expressed in
            pelvic Ganglia of the lower urinary tract
  JOURNAL   Front Neurosci 6, 130 (2012)
   PUBMED   22988430
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6499)
  AUTHORS   Oyama,T., Harigaya,K., Sasaki,N., Okamura,Y., Kokubo,H., Saga,Y.,
            Hozumi,K., Suganami,A., Tamura,Y., Nagase,T., Koga,H.,
            Nishimura,M., Sakamoto,R., Sato,M., Yoshida,N. and Kitagawa,M.
  TITLE     Mastermind-like 1 (MamL1) and mastermind-like 3 (MamL3) are
            essential for Notch signaling in vivo
  JOURNAL   Development 138 (23), 5235-5246 (2011)
   PUBMED   22069191
  REMARK    GeneRIF: Mastermind-like 1 (MamL1) and mastermind-like 3 (MamL3)
            are essential for Notch signaling in vivo.
REFERENCE   6  (bases 1 to 6499)
  AUTHORS   Chalamalasetty,R.B., Dunty,W.C. Jr., Biris,K.K., Ajima,R.,
            Iacovino,M., Beisaw,A., Feigenbaum,L., Chapman,D.L., Yoon,J.K.,
            Kyba,M. and Yamaguchi,T.P.
  TITLE     The Wnt3a/beta-catenin target gene Mesogenin1 controls the
            segmentation clock by activating a Notch signalling program
  JOURNAL   Nat Commun 2, 390 (2011)
   PUBMED   21750544
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 6499)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   8  (bases 1 to 6499)
  AUTHORS   William,D.A., Saitta,B., Gibson,J.D., Traas,J., Markov,V.,
            Gonzalez,D.M., Sewell,W., Anderson,D.M., Pratt,S.C., Rappaport,E.F.
            and Kusumi,K.
  TITLE     Identification of oscillatory genes in somitogenesis from
            functional genomic analysis of a human mesenchymal stem cell model
  JOURNAL   Dev Biol 305 (1), 172-186 (2007)
   PUBMED   17362910
REFERENCE   9  (bases 1 to 6499)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
REFERENCE   10 (bases 1 to 6499)
  AUTHORS   Wu,L., Sun,T., Kobayashi,K., Gao,P. and Griffin,J.D.
  TITLE     Identification of a family of mastermind-like transcriptional
            coactivators for mammalian notch receptors
  JOURNAL   Mol Cell Biol 22 (21), 7688-7700 (2002)
   PUBMED   12370315
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC158347.4 and AC116729.14.
            
            On Oct 5, 2022 this sequence version replaced NM_001004176.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB553633.1, SRR10662774.2633567.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1313              AC158347.4         149016-150328       c
            1314-2891           AC116729.14        9149-10726
            2892-3170           AC116729.14        168382-168660
            3171-3255           AC116729.14        173945-174029
            3256-6499           AC116729.14        175371-178614
FEATURES             Location/Qualifiers
     source          1..6499
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 22.54 cM"
     gene            1..6499
                     /gene="Maml3"
                     /gene_synonym="Mam-2; mKIAA1816"
                     /note="mastermind like transcriptional coactivator 3"
                     /db_xref="GeneID:433586"
                     /db_xref="MGI:MGI:2389461"
     exon            1..1313
                     /gene="Maml3"
                     /gene_synonym="Mam-2; mKIAA1816"
                     /inference="alignment:Splign:2.1.0"
     CDS             849..4256
                     /gene="Maml3"
                     /gene_synonym="Mam-2; mKIAA1816"
                     /note="mastermind-like 3; mastermind-2; mastermind like 3"
                     /codon_start=1
                     /product="mastermind-like protein 3"
                     /protein_id="NP_001004176.2"
                     /db_xref="CCDS:CCDS17342.2"
                     /db_xref="GeneID:433586"
                     /db_xref="MGI:MGI:2389461"
                     /translation="MGDFAAPAAAANGSSICINSSLSSSLGGAGIGVNTPNSTPVAPS
                     GNHPAAGGCGGSGGPGGSSAAVPKHSTVVERLRQRIEGCRRHHVNCENRYQQAQVEQL
                     ELERRDTVSLYQRTLEQRAKKSGAGSGKQQHPSKTQQDAEAASAEQRNHTLIMLQETV
                     KRKLEGARSPLNGDQQNGACDGSFSPTSKRIRKDLGTGLEAINNLPNNMPLTSASPLH
                     QLDLKPSLPLQNSAAHTPGLLEDLSKNGRLPVNGCGDLEDSFAILQNKDLKQEPLDDP
                     ACIDTSETSLSNQNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEQE
                     FSQTTMETPLSQESVSVKSDASHSPFAHVSLGSPQARPSSSGPPFSTVSTGTNLPSVA
                     NTPGAQNPASSPANCAVQSPQTPTQAHTPGQAPPRPGNGYLLNPVSVAVSGSGSGSVA
                     GPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQHSNQTSSWSP
                     LGPPSSPYGTAFASEKPNSPMMYPQAFNNQNTIVPAMANSLQKTTMNNYLPSNHMNMI
                     SQQPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSPRMTPPMANPNKTPLMPYIQQPQ
                     QSQQPQPQPPQQQPPPPPQLQAPRAHLSEDQKRMLLIKQKGVMNPPMAYAALPAHGQE
                     QHAVGIPRTTGPMQNSVPSGSGSMVSGASPGGLGFLGSQPQAAIMKQMLMDQRAQLME
                     HQKQQFLREQRQQQQQQQQQQQQQQQQQQILAEQQLQQPHLPRQHLQQQRNPYPVQQV
                     NQFQGSPQDIAAVRNQVALQSMRASRLIAQNAGMMGMGPSQNPGTMATAAAQSEIGLA
                     SYSAPPTSQPGMYNMNTGMTQMLQHSNQSGMGIPHNQSQGPRPPASSQGVGMVSGFGQ
                     SMLVNSALSQQHQQLKGSVGQALPRPQGPPRLQSVMGTVQQGAQNWQQRSLQGVPGRT
                     SGELGPFNNGASYPLQAGQPRLTKQHFPQGLSQPVMDANTGAVRTLNPAAMGRQMMPT
                     LAGQQSASQVRPLVMPGLSQGVPGMPAFSQPPAQQQIAGGNFAASNQGQAYERTPAQD
                     MSYSYSGEGVGAAFPGLPDSTDLVDSIIKSGPGDEWMQELDELFGNP"
     exon            1314..2891
                     /gene="Maml3"
                     /gene_synonym="Mam-2; mKIAA1816"
                     /inference="alignment:Splign:2.1.0"
     exon            2892..3170
                     /gene="Maml3"
                     /gene_synonym="Mam-2; mKIAA1816"
                     /inference="alignment:Splign:2.1.0"
     exon            3171..3255
                     /gene="Maml3"
                     /gene_synonym="Mam-2; mKIAA1816"
                     /inference="alignment:Splign:2.1.0"
     exon            3256..6499
                     /gene="Maml3"
                     /gene_synonym="Mam-2; mKIAA1816"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6466..6471
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Maml3"
                     /gene_synonym="Mam-2; mKIAA1816"
                     /note="hexamer: TATAAA"
     regulatory      6472..6477
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Maml3"
                     /gene_synonym="Mam-2; mKIAA1816"
                     /note="hexamer: AATATA"
     polyA_site      6486
                     /gene="Maml3"
                     /gene_synonym="Mam-2; mKIAA1816"
                     /note="major polyA site"
     polyA_site      6499
                     /gene="Maml3"
                     /gene_synonym="Mam-2; mKIAA1816"
                     /note="major polyA site"
ORIGIN      
        1 actccgctgg catggaggag gaggaggagg tggaggagcg cgaggaggag gaggaggcgg
       61 cggcggcggc gagcagttga tcattgtgat ggtggcggag gcggcggcgg cagcggcagc
      121 ctggccgagc attagtggct gctctccgcg cggcgtttcg caaaggactc cagcgatcta
      181 cttttgcagt cgcctcggac tgtccatgtg tttacttgcc cagcccgagg actcgatgtc
      241 taggctcctg tgaaatgcaa ctgagcagcc aaagtacttt gagaacacgg ggcggcataa
      301 acaccaaaac ttttttgtgg aaggaaaatg caataagcaa gctcgccgtt ttccgatgcg
      361 gcgtggagtg agtgtgtgtc gcgcgtgtcc gcactggagg cacacgctcg tgtgtgtaca
      421 tggggtgtgt ttttcggtac gtagggagaa aatgcttgcc aaccaccgga aacctcctgg
      481 aatttattag aaaataatgg attattaaaa ggaggcaggc gaggagcgga tctccccttg
      541 agttgcaagc cgatctgctg ccggctcagt ttgttgggat tctatttgtt gataggtgtc
      601 tgatggtatt ctgataacac cccctttttt tctcccctcg atctttacag tttttttaag
      661 gaaaaaaaac accccaaaat ctcttccccc ttttttcacc ccgtggggat cgctgttttt
      721 tcatccatgt gcttgcgtct cccccgcgtt ccacttaaac tattttaatc cttggaccca
      781 aggagaaggc tgataggggg tggattaaaa aaaaaagttc ttccaaaata gtgtgccccg
      841 ggagcaggat gggggatttc gcagcccccg ctgccgccgc gaatggtagt agtatctgca
      901 tcaacagcag cctgagcagc agcctcggcg gggccgggat cggcgtgaat actcccaata
      961 gcactccggt tgctccgagt ggcaatcacc ccgctgccgg cggctgcggc ggctccgggg
     1021 gccccggcgg cagctcggcg gccgtcccca agcacagcac ggtagtcgag cggctccgcc
     1081 agcgcatcga gggctgccgg cggcaccacg tcaactgcga gaacaggtat cagcaggctc
     1141 aggtggagca gctggagctg gagcgccggg acaccgtgag cctctatcag aggaccctgg
     1201 agcagagagc caagaaatcg ggcgccggca gcggcaagca gcagcacccg agtaaaaccc
     1261 agcaagatgc ggaggctgcc tcagccgagc agaggaacca tacgctgatc atgctgcaag
     1321 agactgtgaa gaggaagttg gaaggggccc gatcgccact aaatggggac cagcagaatg
     1381 gcgcttgcga cgggagcttc tctcccacaa gcaagcgcat ccgaaaggat cttggcacgg
     1441 ggctggaagc catcaacaat ttgcccaaca acatgcccct gacgtcagca tctccccttc
     1501 accaacttga cctcaagcct tctttgccct tgcagaacag cgctgctcac acccctgggc
     1561 ttctggaaga tctgagtaag aacggcaggc tccctgtcaa tggctgtggg gatctggagg
     1621 atagctttgc tatcttacag aacaaggacc tcaaacagga gcctcttgac gaccctgcct
     1681 gcatagacac atcggagacg tccctttcta atcagaacaa gctgttctct gacattaacc
     1741 tgaatgacca agagtggcaa gaactaatag acgaactggc caacacggtt ccggaagacg
     1801 acatccagga cctgttcaat gaagactttg aagagaagaa ggagcaggag ttctcacaga
     1861 caaccatgga gacgccactc tcccaggaga gcgtgagtgt gaagagcgat gcctctcact
     1921 ctccttttgc acacgtctct ctgggatcgc ctcaggccag accctcatct tctggtcctc
     1981 ccttttccac tgtctccaca ggcactaact tgccatccgt ggccaacact cccggggctc
     2041 aaaaccctgc cagctcgcca gctaactgtg ctgtccagtc cccccagact ccaacccaag
     2101 cccacacccc aggtcaagcc ccacctaggc ctggcaatgg ctatctcctt aatccagtct
     2161 ctgtggcagt atctggttca gggtcaggct ctgtggcagg gcccagctct gacatgtccc
     2221 cagcagagca gctcaaacag atggctgccc agcaacaaca gagggcaaaa ctcatgcagc
     2281 agaagcaaca gcagcagcag caacagcagc agcagcagca gcaacaacaa caacaacagc
     2341 agcactcaaa tcagacttca agttggtctc ccttagggcc tccgtcaagt ccatatggaa
     2401 cagcttttgc ttcagaaaaa ccaaatagcc caatgatgta cccccaagcc tttaacaacc
     2461 aaaacactat agtgcctgca atggcaaaca gcctgcagaa gacgaccatg aacaactacc
     2521 tcccttccaa tcacatgaat atgatcagtc agcagccaaa taacttgggt acaaactcct
     2581 taaacaaaca gcacaatatt ctcacctatg gcaacactaa gcctctgacc cattttaatg
     2641 cggacttgag tccgagaatg acgcccccta tggccaaccc caacaaaacc cccttgatgc
     2701 cctacatcca gcagcctcag cagtcgcagc agccccagcc gcagccgccc cagcagcagc
     2761 caccgcctcc cccgcagctg caggctccca gggcgcacct gagcgaggac cagaaacgca
     2821 tgcttctcat taagcagaaa ggagtgatga acccacccat ggcctatgct gcgcttcctg
     2881 cccacggtca ggagcagcac gcagtcggta ttccccggac cacaggccct atgcagaact
     2941 ctgtgccctc ggggtcgggc agcatggtct ccggagccag tcctgggggc cttggatttc
     3001 taggcagcca gccacaggca gccatcatga agcagatgct aatggaccaa cgggcccagc
     3061 tgatggagca ccagaagcaa cagttccttc gggagcagag gcagcagcag caacagcagc
     3121 agcagcagca acagcagcag cagcagcagc agcagatcct ggctgagcag cagttacagc
     3181 agccgcacct gccccgtcag cacctccagc aacagcggaa cccataccca gtgcagcagg
     3241 tcaaccagtt tcaaggttca ccccaggaca tagcagctgt gagaaaccag gtggctctcc
     3301 agagcatgcg agcatcgagg ttgattgcac agaatgcggg catgatggga atgggaccct
     3361 cccagaaccc agggacgatg gctacggcag cagcgcagtc agagataggt ctggcctctt
     3421 acagtgcccc tccaaccagc caaccaggaa tgtacaacat gaacacagga atgacccaaa
     3481 tgttgcagca ttccaatcag agtggaatgg gcatcccaca caaccaatcc cagggaccca
     3541 ggccgccagc ctccagccag ggggtcggca tggtgagcgg cttcggtcag agcatgctgg
     3601 tgaactcggc tctctcgcag cagcaccagc agctgaaagg gtctgtgggc caggccttgc
     3661 ctaggcccca gggccctcca aggcttcaga gtgtcatggg aaccgtccag caaggagcac
     3721 aaaactggca acagaggagc ttacaagggg tgcctgggag gactagtggg gagttgggac
     3781 cattcaacaa tggcgccagc tacccattgc aagccggtca gccaagactg accaaacagc
     3841 acttcccaca ggggctgagc cagcccgtca tggatgctaa cactggcgca gtgagaaccc
     3901 tcaacccagc agctatggga cgtcagatga tgccaaccct ggcaggacag cagagtgcca
     3961 gccaggtgag gccattggtc atgcctggtc tgagccaggg tgtccctggc atgccagcat
     4021 tcagccagcc cccagcacag cagcagatag caggtggcaa ctttgctgcg agcaaccagg
     4081 gccaggccta tgagcggacc cctgctcagg acatgtcata cagttatagc ggcgaaggtg
     4141 tcggggctgc cttccctggc ctcccagaca gtacagacct cgtggactcc atcatcaaaa
     4201 gtggcccagg ggatgaatgg atgcaagagc ttgatgaact gtttggtaac ccctagtcag
     4261 gaggagccct aagagctgta gaagcctcac aagtggaaag gaaacaggat ggagacccat
     4321 ccttgttttt tttgtttttt tgacccacgt aaattgagaa catgacatcc ggctgacagt
     4381 agaaggcaca ggtgtccatc cccagctccg tggggggcat cgttccacct gacttccaca
     4441 gagcaatcaa gtagagagga cgtgccgata cctgcccgca gagaagggat gtagagagca
     4501 ggtggggaaa tcgaggcaac gggagctcct ctgctaagca cccctgggat cttctggtcc
     4561 agaaggagct gttccagccc agagggacca tggcccaaga tgaggtcccc ttaggccttc
     4621 ctgcctcagg tcccgagacc tcagctttgg agatgagaga tggagcctcg gccagaaaaa
     4681 aaaaaaaaat cccggcatga agatgcacac gtgccatgtg cataggtcag aaggagatgt
     4741 gtgcttccag acacgttcct ggattcggag gcaggaacaa agaactgtga gctcacctga
     4801 gctggcccta ggaaccaagc caagatcctc caggcctgtc tgtctcctgc ccagcgacga
     4861 ccctcaggga tggtaaggtg ttgctgccag ccacctcacc aggatagcca actatgctta
     4921 agaagggccc agctcgtagc cctgatggtc agcttcagct ggaggccatg gtggccatca
     4981 ctctagttga gctctcatcc agtttaacac atctggctgg ttttcctatg cttatggcca
     5041 catgggtggg aagacttcct gctgagttca gtgtctgcca agccgggccc catccacact
     5101 cacccctgcc tccactcctc ccggtctcta tgccagcctg cctttatctc tccctccaga
     5161 cttccagact atccgggaag tgttgcactg aggcagagtc tacgtaactg caaggatata
     5221 cacagtgcct ggcgtgcgaa ggtgatactg gaatctcttc caccacgtgg aaagtcaact
     5281 gtctccacca gagcagagtg ggctggctgc actgatagga cctgccggtt tataagagcc
     5341 acacccatac tcctgctgtc cccagggagg aatggcctga agatgcccag ttctttcaga
     5401 tggtgtcatc gatgacactc cagaatcagc cttgcttgtc aactccagca tcaggaagac
     5461 aaatatcaaa tgtgagagat ggaaaagctg aactgcataa ctccgtctta actatctgga
     5521 tgctgaagag aggaaaggga ggtgtggccg ctatcctaat ggcgctcact ccacttccaa
     5581 agctgggcag ccattctcgt tggaactcat acatgcctgc cggagtgaaa actaagaagt
     5641 gaacagtctc catggtcaca agccttgtcc cttggtcttt acctcccctc ccacagtccc
     5701 atcttggaag tcatgtgatg tttgtctgtg ttgtttactt tcctcctggc cacacacaca
     5761 cacacacaca cacacacgtg cgtgcgcata tcagagcaca catacatcct acaaactggc
     5821 ttccttctct gtcttcacat acatcttact acagaagacc ggagcctgtg gggacttaag
     5881 tggccatacc taagaaagtg cagacagaca gggtgcactg cagtagaaag ctgaggtgag
     5941 gtgccaggga gagggggaga gagggtaacc cttggtttgt cctccatatc ccccagagtt
     6001 ccagacctgc tcagacagga agtaaagcca gaggtaccag ggtgaggagc tgtgtgcctc
     6061 tccaaagagg tggtggcaag gagactgtga cctcccggaa tggggaggaa ctgccactag
     6121 ggaaacacat ggaaaccaaa aaataaaaat taaaaaaaat agtaaatcaa aaaagcctag
     6181 aatacaaatt tatcactttt tcctgccagg tacagggaag aaatgtacaa gcaatgatga
     6241 gaagctggag gtggcgagag ggggcttgtt gtcttctaaa gcctcctgca agtgccccgt
     6301 ctgaggacca actaatagag tggtagattt taatgagctt gttttggttt tgtttttact
     6361 acggtgctga tgtatatgta atgtctaaaa aaaaaaagct atttgtaaat aagtttttac
     6421 aatgctacag atatcactgg gtctactata tgtaaaaagt atacatataa aaatatatat
     6481 atataatgtt tgtttaaaa
//
