LOCUS       NM_001013813            7795 bp    mRNA    linear   ROD 08-AUG-2023
DEFINITION  Mus musculus mastermind like transcriptional coactivator 2 (Maml2),
            transcript variant 1, mRNA.
ACCESSION   NM_001013813 XM_486183 XM_486184
VERSION     NM_001013813.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7795)
  AUTHORS   Moayedi Y, Basch ML, Pacheco NL, Gao SS, Wang R, Harrison W, Xiao
            N, Oghalai JS, Overbeek PA, Mardon G and Groves AK.
  TITLE     The candidate splicing factor Sfswap regulates growth and
            patterning of inner ear sensory organs
  JOURNAL   PLoS Genet 10 (1), e1004055 (2014)
   PUBMED   24391519
REFERENCE   2  (bases 1 to 7795)
  AUTHORS   Oyama T, Harigaya K, Sasaki N, Okamura Y, Kokubo H, Saga Y, Hozumi
            K, Suganami A, Tamura Y, Nagase T, Koga H, Nishimura M, Sakamoto R,
            Sato M, Yoshida N and Kitagawa M.
  TITLE     Mastermind-like 1 (MamL1) and mastermind-like 3 (MamL3) are
            essential for Notch signaling in vivo
  JOURNAL   Development 138 (23), 5235-5246 (2011)
   PUBMED   22069191
REFERENCE   3  (bases 1 to 7795)
  AUTHORS   Koo BK, Lim HS, Song R, Yoon MJ, Yoon KJ, Moon JS, Kim YW, Kwon MC,
            Yoo KW, Kong MP, Lee J, Chitnis AB, Kim CH and Kong YY.
  TITLE     Mind bomb 1 is essential for generating functional Notch ligands to
            activate Notch
  JOURNAL   Development 132 (15), 3459-3470 (2005)
   PUBMED   16000382
REFERENCE   4  (bases 1 to 7795)
  AUTHORS   VanBuren V, Piao Y, Dudekula DB, Qian Y, Carter MG, Martin PR,
            Stagg CA, Bassey UC, Aiba K, Hamatani T, Kargul GJ, Luo AG, Kelso
            J, Hide W and Ko MS.
  TITLE     Assembly, verification, and initial annotation of the NIA mouse
            7.4K cDNA clone set
  JOURNAL   Genome Res 12 (12), 1999-2003 (2002)
   PUBMED   12466305
REFERENCE   5  (bases 1 to 7795)
  AUTHORS   Wu L, Sun T, Kobayashi K, Gao P and Griffin JD.
  TITLE     Identification of a family of mastermind-like transcriptional
            coactivators for mammalian notch receptors
  JOURNAL   Mol Cell Biol 22 (21), 7688-7700 (2002)
   PUBMED   12370315
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            MH423685.1, AC169127.3 and AC155923.2.
            
            On Aug 13, 2022 this sequence version replaced NM_001013813.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219380.51312.1,
                                           SRR17253014.3555220.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1851              MH423685.1         17835-19685
            1852-3537           AC169127.3         98461-100146
            3538-3741           AC155923.2         32082-32285         c
            3742-3853           AC155923.2         27104-27215         c
            3854-7795           AC155923.2         19926-23867         c
FEATURES             Location/Qualifiers
     source          1..7795
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 3.33 cM"
     gene            1..7795
                     /gene="Maml2"
                     /gene_synonym="5930431H10"
                     /note="mastermind like transcriptional coactivator 2"
                     /db_xref="GeneID:270118"
                     /db_xref="MGI:MGI:2389460"
     exon            1..1851
                     /gene="Maml2"
                     /gene_synonym="5930431H10"
                     /inference="alignment:Splign:2.1.0"
     CDS             1354..4866
                     /gene="Maml2"
                     /gene_synonym="5930431H10"
                     /note="isoform 1 is encoded by transcript variant 1;
                     mastermind like 2"
                     /codon_start=1
                     /product="mastermind-like protein 2 isoform 1"
                     /protein_id="NP_001013835.2"
                     /db_xref="CCDS:CCDS90496.1"
                     /db_xref="GeneID:270118"
                     /db_xref="MGI:MGI:2389460"
                     /translation="MGDTAPPQAPAGGLGGASGAGLLGGGSVTPRVHSAIVERLRARI
                     AVCRQHHLSCEGRYERGRAESSDRERESTMQLLSLVQHGQGARKASKHAKATVATATT
                     TAPPPPPTAPPVASQAAATAPPPPPDYHHHHQQHRLTSNDNGGINREQPPASTPGDQR
                     NSALLALQGSLKRKQIVNLSPANSKRPNGFVDSSFLDIKRIRVGENLSTGQGGLPVNN
                     GQSQMMPGPLTMNQAPLRKTNALPPPAHSPGNNLFNMGLKEVKKEPGETLSCSKHMSD
                     QMTQESVFTNRFGDDPGDQLMDPELQELFNELTNISVPPMSDLELENMINATIKQDDP
                     FGIDLGQQSQRSTPRPSLPMEKIIIKSEYSPGLTQGTSGSPQLRPPSAGPAFSLANSA
                     LSTSSPIPTIPQSQPQLQTVSGANRALSSWQEVSHAQQLKQIAANRQQHARMQQQQQQ
                     QQQQPSPSWPALQSSAGPSPGAFVQEKIPSPSFSQQPFSPQGSPMPGVTGSNTQSKAA
                     ANYTYKASPSAQAGHLDVLLQQKPQELNRSFINNPHPALEPRHGNTKPLFHFNSDQAN
                     QQMPSLLPSQSKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ
                     QQQQQQQGSLAAQQQQQQPQPQSSLVAQQQQQQQQQQQQQQGSLTAQQQQQQQQQQQP
                     SQPTHALSSQPLLRSPLQLQQKIMLQKMQTQSITGLGYQVTQQHRQDQHTVVGQNTGP
                     SPSPNSCSNPNTGSGYMNSQQSLLNQQMMGKKQTLQRPTMEQKQQLLLQQQMLADAEK
                     LSPQDQMNRHLTRPPPDYKDQRRNTGTLQPAAQYSGGSSTVSLNSNQALTNPVSTHTI
                     LTPNSSLMSTSHGMRMPLLSTVQNIGMYGNLPCNQPGTYNVTSTMNQLTQQRNTTQLI
                     TNQNNPLMSRPSPLGANNGNNVATFGAGSAGSSQQLRPNLAHSLSGMSAQRSSTVMIT
                     ANTTATNWASQEVTGKQQEALKSTGVRFPTSTPAAYTPNQSLQPGVGSQPFSQRAVAP
                     PSQLSPAVQMRPMNQMNQALNGQTLGSLRGLNLRPNQLAAQSLSNMNPSGTGLNHPRT
                     GTNQPPSLTPNAFPSSNQSSRAFQGPDHGSDLAFDFLSQQSDSMCPALNSDADFIDSL
                     LKTEPGNDDWMKDINLDEILGSNS"
     exon            1852..3537
                     /gene="Maml2"
                     /gene_synonym="5930431H10"
                     /inference="alignment:Splign:2.1.0"
     exon            3538..3741
                     /gene="Maml2"
                     /gene_synonym="5930431H10"
                     /inference="alignment:Splign:2.1.0"
     exon            3742..3853
                     /gene="Maml2"
                     /gene_synonym="5930431H10"
                     /inference="alignment:Splign:2.1.0"
     exon            3854..7795
                     /gene="Maml2"
                     /gene_synonym="5930431H10"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctcctccccc atctgcagcc tgctggctcc ctctctctct ctgtctcact ctctctctcc
       61 ctctctctct ctttctctcc ctctcgtatc gcagcacaat gaaagcctgt gtttcgccgt
      121 gagtccgagg agcgggagtc ggtgtcagga aagcgctcgg aacagacctg aaagagaaag
      181 gaaaatacaa gcgacttttt tcttctctcc ccccccccac ccgccccatc tataaagcga
      241 agcattacaa gagatagagc cacattgcct ttgggagtcc agaccctctg agccactggc
      301 cgggcatgga atatacaaaa ctggacagaa aagtggctgg acatgactcg gtgcaatttg
      361 ctggaagttt gtaagtttga ccatcgtttg taaattactc tcagaagact ttgtctgtct
      421 tgatactgta ttagaataga agtggggagg gggagaggaa taaaaacgta agtgggaaag
      481 ggggaaatgt gttgaaggag ctcagtagcc agccacttca gactgctttc atttaagact
      541 aagaaaccta agagggaatc gggacttttg ccggtgattg gattagcttg aagaaaagag
      601 catggttctg aagtccaatt actgacgttg ttaagactga aaagctgtct tctttgggga
      661 gaggactaca tccttctgtc cccccacccc gaggagaaaa caccaacacc ggagggagag
      721 gaagggacgg agaaaccaac atagtcttct ctgatttcgc acagtttgaa catgacttcg
      781 ggagccttgg gaaacagtcc tgttgtttgt tttttaacct gaggaaaagt gaaggctgcc
      841 ggttccacag cccccaggag aaatgtgttt ctctgcagaa atacccctat aaataatttc
      901 ccgaagcagc taggtgaggg ggagcccgga tctctagtaa tgactctatt gattcctttt
      961 gctacgtgct tctgcctctt ccttgacaat ccctgaattc ttgaactgtc ccctagactt
     1021 tgtgtttaca aagtacctag aggctcttgt cagcctggtg ggggagaaaa aaaaatctac
     1081 caactccgtc caacttctcc tgagctgtca aatgcaatta gagtaagttg atcagggttt
     1141 gtttccaact tcctctctcc aattggtttc taatctttct cccctccctc ttgttactcg
     1201 ctcccctccc ccacaccctc ttcactgtct ccccaccctc tggagacctc tattcatgtg
     1261 ccctgaacac tgaaaccagc tttgcctgca atagccagca ccagcctctt gcacctcacc
     1321 atcccagagg cagtaatcat tgtgtccaac aagatggggg acacagcgcc cccgcaggcc
     1381 cccgcaggag ggttgggagg ggcttctggg gcggggctcc ttggaggggg ctcagtcacc
     1441 ccgagagtgc acagtgctat tgtggaacgc ctgcgggctc gcattgctgt ctgccgacag
     1501 caccacctga gctgtgaagg acgctatgaa cgtggtaggg ctgagagctc agaccgagag
     1561 agggagagca ccatgcagct tctcagcctg gtgcagcatg gtcagggggc aaggaaggct
     1621 agcaaacatg ctaaggctac agtcgcgact gccactacca cagctcctcc accgccccct
     1681 actgcccctc ctgtggcctc ccaagcggca gccacggccc caccacctcc accagactat
     1741 caccatcacc atcagcagca ccggctgacc agtaatgata acggtgggat aaaccgagag
     1801 cagccgccag cttcgacccc gggggaccag cggaactcag ccctgcttgc gctccagggc
     1861 tctttgaaaa gaaagcaaat agtcaacttg tctcctgcca acagcaagag gcccaatggc
     1921 tttgttgaca gctcatttct tgacatcaaa aggatcagag ttggggagaa cctttctaca
     1981 ggtcaggggg gcctcccagt aaataatgga caaagtcaaa tgatgccagg gcccttgacc
     2041 atgaatcaag cacccctgag gaagactaat gctctaccac ctcctgcaca ttcccctggc
     2101 aacaatttgt ttaacatggg cttaaaggag gtgaagaaag aacctgggga gaccctgtcc
     2161 tgcagtaagc acatgagtga ccaaatgaca caagagagtg tttttactaa taggtttgga
     2221 gatgaccctg gagatcaact gatggaccct gagctacagg aactgttcaa tgaactaacc
     2281 aacatatcag tgcctcccat gagtgacctg gagctggaga acatgatcaa tgctaccatt
     2341 aagcaagatg acccgtttgg cattgacttg ggtcagcaga gccagaggag cacacctaga
     2401 ccctccctgc ccatggagaa gatcattatc aaaagtgaat attcacctgg tttgacacaa
     2461 ggcacttcag gctctcccca gctgagaccc ccatcagctg gccctgcatt ttccttggct
     2521 aactctgcac tctccacttc atccccaatt cccacaattc cccagagtca gcctcagctt
     2581 cagacagtat caggagcaaa cagggccctg tcaagctggc aagaagtatc ccatgctcaa
     2641 cagctcaagc agatagctgc aaaccgccag cagcatgcac ggatgcagca gcagcaacag
     2701 cagcagcagc agcagccatc tcccagctgg ccagccttgc agtcctctgc tgggccatcc
     2761 ccaggagcat ttgtgcagga aaaaatccct agcccttcct tcagccagca accattcagt
     2821 ccacagggat cccccatgcc tggggtgact ggcagcaaca cccagtctaa agcagcggcc
     2881 aattacacgt acaaggccag cccctcagcc caggctggac acctggatgt gcttctgcag
     2941 caaaagcctc aggagctcaa tcgaagcttc attaataacc cacacccagc cttggagccc
     3001 cggcatggca ataccaagcc tttgttccat tttaactcag accaagcaaa ccagcagatg
     3061 ccttctcttt tgccttccca gagcaaacct tctctcttgc actataccca gcagcagcag
     3121 cagcagcagc agcagcagca gcagcagcaa caacaacaac aacagcagca gcagcaacag
     3181 cagcagcaac aacaacaaca gcagcagcaa caacaacagc agcagcagca acaacaacaa
     3241 cagcaaggct ccctggcagc tcagcagcag cagcagcagc cacagccaca gagttcattg
     3301 gtagctcagc agcagcaaca gcagcagcaa cagcagcagc agcagcaagg ttcattgaca
     3361 gctcagcagc agcagcaaca gcagcagcag cagcaaccat cgcaacccac ccatgcttta
     3421 tcaagccagc ctttgctaag gtcaccctta caacttcagc aaaagatcat gcttcagaaa
     3481 atgcaaactc agtccatcac aggcctggga tatcaagtca ctcaacagca cagacaggat
     3541 caacacactg tggtaggcca gaacacaggc cccagtccaa gtcccaactc ctgctcaaat
     3601 ccaaacactg gaagtggtta catgaactcc cagcagtccc tgttgaatca gcagatgatg
     3661 gggaagaaac agaccctgca gagaccaacc atggagcaga agcagcaact tctcctccag
     3721 cagcagatgc tggctgatgc ggagaaactt tcccctcagg atcagatgaa cagacatctg
     3781 acaaggccgc ccccagacta caaagaccaa agaagaaata cgggcaccct gcagccagct
     3841 gctcagtatt cgggtggctc ctctacagtg agtttaaact ctaaccaggc tctgacaaac
     3901 ccagtttcaa cacacaccat tttaactcca aactccagcc tcatgtctac gtctcatggg
     3961 atgagaatgc cattgttatc tacagttcag aacataggga tgtatggaaa cctgccttgt
     4021 aaccagcctg gcacctacaa cgtcacttca acaatgaacc agctgacaca acagagaaat
     4081 acaactcaac tgataacaaa tcagaacaac cctctgatgt ctcggccatc tcccttaggg
     4141 gcaaataacg gtaacaatgt ggccaccttt ggagctggat ctgctggcag ttcacagcaa
     4201 ttgagaccaa atttggctca cagtttgtca ggcatgtcag cccagaggtc atcaactgtc
     4261 atgatcacag ccaacacgac agcaacaaac tgggcttctc aagaggtgac agggaaacaa
     4321 caggaagccc tcaaatccac aggagtccgg ttcccaacaa gtacacctgc agcctatacc
     4381 ccaaaccagt ctttgcaacc aggagtaggg agccagccat tttcccagag ggcagtggca
     4441 ccccctagcc agttatcgcc agcagtgcaa atgagaccta tgaaccaaat gaatcaggca
     4501 ttaaatgggc aaaccctggg ttcactcagg gggttgaacc tcagacccaa tcagctggcc
     4561 gcccagagcc tgtctaatat gaacccatca gggacaggat tgaatcatcc caggacaggc
     4621 accaaccagc ctccatccct gacacctaac gcttttcctt catccaacca aagttccagg
     4681 gcttttcaag gacctgatca tggcagtgat ttagcttttg acttcctcag ccaacagagc
     4741 gacagcatgt gccctgccct aaacagtgat gctgatttca tcgattcttt attgaagaca
     4801 gagcctggta atgacgactg gatgaaagat atcaaccttg atgagatcct gggaagcaat
     4861 tcctaaggtg gaaggaagat gatccgcagg ctctgagcag ggcttttcaa ggatactgta
     4921 atgccaaact gctgaagtct gggggaacta cagacctcaa aacagaaggt tggcgggaac
     4981 cacagtggtg aacattttgt tttacatgct tgttttaaaa aatcttgagc ctgatagtaa
     5041 aacattggga ttgtttttcc ctgcctgaac ttcaggatat gtaatccagt ttatccaaac
     5101 acaactgtga tgctgatgtg taattaattg tgtaaattgg tcttcccaag ttccttttct
     5161 cagtgaagga agtacaatag aacttgagac ctgtttcaat cccatatcat aatagacaga
     5221 tgcttgttct aaacaacagg cagcagactg tcatctagta gataaatatg gtttgacttc
     5281 tctgttgtta tttgtcttgc aggaaatatt gaaatgttac atggctgtgt ggagtaacct
     5341 aagagggatt cagagaacct agaagctatc cagcagatta attgatttcc ttcctagatg
     5401 cactcctcat ttttgtaact ttcccacgtg ttttgtattt tggtgagatg ctgtgtctca
     5461 tgataaaaca ggaatgcagg gcttgcaacc tgactggggc ttcactccct cccatttttt
     5521 tttttttttt ttttttttag ataaccaaga ctggtcctga ttatgctgaa ataccagtgc
     5581 acaacagcct gtatcgaatt tcacttcaaa aaaaaaaaaa aaaagttaag ccttgccatg
     5641 taggaaaaaa acatggccac gaatgaccag cagtgttgct cactgtgatt aatagccact
     5701 ggtctgttcc caagcagaat gaaatggagc ctcctaggtc ttggtagcca gagactggtt
     5761 tgtaaaaaaa aaaaaaagaa aagaaaagaa agaaagaaag gaatgaaagt gtgaattaga
     5821 gtcagattag agaatatcct gttttggttg aaggtaagaa acagggagag gcatgagagg
     5881 gcacgaagca tttcacagag ctcagaggaa acagtacctg acagacagta tagcttttcc
     5941 ttggacatac tacatggact taggtgagca gctaagccca gtgtggtctc tgtggagcca
     6001 cccactcact attcatgatg cagcaagccc ttgccatatg gtgcctggcc cttcttatcc
     6061 aggtttcctc cctcagggct gagtgttata gcagaacatg catgtgtctg ggtcacggaa
     6121 cctcagtgca cacatctatg tacactgcaa agtggagctg gtatccaggt ttgaaaggca
     6181 tctaaaagag cactaccacc ttcctaaatc cagagaatca aaggctactt tcaatctttg
     6241 agttagcaat gcacacacta aaataccaag tgtgattgac ttgaagttat caagcacctg
     6301 atcttcacaa acctgttcag aaaaggaaca cggtttttta aagctctgca aagtcctctt
     6361 cttgtcttta cgatggcttt gggctctctg tctttcccac tgcaccaata tcactggccc
     6421 agagtatttt ctgtgctggt ttgtaaatat taataaattt cttgttttgt aaacttttgt
     6481 aaagaatatt ttggtagaaa tacttaaaac atattctttg gattatattt atacatatgt
     6541 gaaataaata tactatcgaa aggttatatt ttatacaaaa agtaaattgt taccttttgt
     6601 atgctaatat acaaagtttt gtatcataca atggtttatt tttagctcta catttaaacc
     6661 atacgtgatt gagtggaagc tttgaaaacc cactaagagg cttgttaggt aaatgtgtat
     6721 cctgagacct ccctcagaaa gcattcctgg gtccatccct ccctgttctt gttttccagc
     6781 tcagatcctt tatgaagccc agagtcctca tgtctcattt gatgattctg ctgtgcacac
     6841 aacagttcct gttgcatgtg tcctactgtg tgtctcccca ttatacaaaa cagtgtttct
     6901 ccatgagaac agagagggaa aacaatgtat atatataaac gccatggttt tgtggctcct
     6961 ccagatggct ggacatatct gcaggacttc tcagtctccg accatataat tcagcttgtt
     7021 tctccctaac ccaaacagta cattctacag cagctgtcca gttgtccaac tgaagaggca
     7081 aaggaaacaa catggctggt ttttcttctc ttaatgtgaa tttcataatt aatgtctatt
     7141 tattcagcta ttcattaaaa tacaggattc tttgggggag acagtatagc ctatagtttt
     7201 tctgtttgtt agcagcctat taccaaagat gatgtaattt tcctgaaagc tgagataatg
     7261 acaatttgat agacaaactt agtaagagcc tcaggattta caatgtaaga gctattggga
     7321 tacaaactcc catttataga catgctagac tacttagttg ctgacattgt ttatcattct
     7381 gacatctaac agagaaagta agagtcgttt gtctttcttc tacttccttc ttccctcctt
     7441 cctccctcct cctcctcctc ctaattcaga gactagaaag taatgtaggc aaataattcc
     7501 ttcttggctt tgtgttcagc ctaatgaatg gagtcactga atgaaatgct aatgtcacct
     7561 gcattgctgt cctgaaccca cgaatgtaaa gatttcaact tgtaatacaa gcattttgta
     7621 ttgtgtgtaa ttccatgtgt aaaaaaatag tttaaaacaa ttcagaagtg gttttcttct
     7681 atgaagtcat actgtcagtt atcaatagca tcattacagt taggataact aatgttaaca
     7741 gtaatgggca catatacaca aattgttcta tttaaaagat ttattttata ctttt
//
