LOCUS       NM_174857               3338 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus MAM domain containing 2 (Mamdc2), mRNA.
ACCESSION   NM_174857
VERSION     NM_174857.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3338)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3338)
  AUTHORS   Yorgan,T.A., Peters,S., Amling,M. and Schinke,T.
  TITLE     Osteoblast-specific expression of Panx3 is dispensable for
            postnatal bone remodeling
  JOURNAL   Bone 127, 155-163 (2019)
   PUBMED   31202927
REFERENCE   3  (bases 1 to 3338)
  AUTHORS   Klein,A.D., Ferreira,N.S., Ben-Dor,S., Duan,J., Hardy,J., Cox,T.M.,
            Merrill,A.H. Jr. and Futerman,A.H.
  TITLE     Identification of Modifier Genes in a Mouse Model of Gaucher
            Disease
  JOURNAL   Cell Rep 16 (10), 2546-2553 (2016)
   PUBMED   27568557
REFERENCE   4  (bases 1 to 3338)
  AUTHORS   Manabe,R., Tsutsui,K., Yamada,T., Kimura,M., Nakano,I., Shimono,C.,
            Sanzen,N., Furutani,Y., Fukuda,T., Oguri,Y., Shimamoto,K.,
            Kiyozumi,D., Sato,Y., Sado,Y., Senoo,H., Yamashina,S., Fukuda,S.,
            Kawai,J., Sugiura,N., Kimata,K., Hayashizaki,Y. and Sekiguchi,K.
  TITLE     Transcriptome-based systematic identification of extracellular
            matrix proteins
  JOURNAL   Proc Natl Acad Sci U S A 105 (35), 12849-12854 (2008)
   PUBMED   18757743
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC124557.4,
            AC131118.4 and AC144941.7.
            
            On May 1, 2007 this sequence version replaced NM_174857.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK035566.1, AK154219.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-298               AC124557.4         48610-48907         c
            299-412             AC124557.4         48165-48278         c
            413-684             AC131118.4         53472-53743
            685-769             AC131118.4         55056-55140
            770-907             AC131118.4         58351-58488
            908-1164            AC131118.4         68440-68696
            1165-1258           AC131118.4         73163-73256
            1259-1402           AC131118.4         78959-79102
            1403-1668           AC131118.4         81542-81807
            1669-1762           AC131118.4         98322-98415
            1763-1915           AC131118.4         101368-101520
            1916-2175           AC144941.7         17040-17299
            2176-2260           AC144941.7         24165-24249
            2261-3338           AC144941.7         24375-25452
FEATURES             Location/Qualifiers
     source          1..3338
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 18.22 cM"
     gene            1..3338
                     /gene="Mamdc2"
                     /gene_synonym="1200015L10Rik; mamcan"
                     /note="MAM domain containing 2"
                     /db_xref="GeneID:71738"
                     /db_xref="MGI:MGI:1918988"
     exon            1..298
                     /gene="Mamdc2"
                     /gene_synonym="1200015L10Rik; mamcan"
                     /inference="alignment:Splign:2.1.0"
     exon            299..412
                     /gene="Mamdc2"
                     /gene_synonym="1200015L10Rik; mamcan"
                     /inference="alignment:Splign:2.1.0"
     exon            413..684
                     /gene="Mamdc2"
                     /gene_synonym="1200015L10Rik; mamcan"
                     /inference="alignment:Splign:2.1.0"
     exon            685..769
                     /gene="Mamdc2"
                     /gene_synonym="1200015L10Rik; mamcan"
                     /inference="alignment:Splign:2.1.0"
     exon            770..907
                     /gene="Mamdc2"
                     /gene_synonym="1200015L10Rik; mamcan"
                     /inference="alignment:Splign:2.1.0"
     exon            908..1164
                     /gene="Mamdc2"
                     /gene_synonym="1200015L10Rik; mamcan"
                     /inference="alignment:Splign:2.1.0"
     exon            1165..1258
                     /gene="Mamdc2"
                     /gene_synonym="1200015L10Rik; mamcan"
                     /inference="alignment:Splign:2.1.0"
     exon            1259..1402
                     /gene="Mamdc2"
                     /gene_synonym="1200015L10Rik; mamcan"
                     /inference="alignment:Splign:2.1.0"
     exon            1403..1668
                     /gene="Mamdc2"
                     /gene_synonym="1200015L10Rik; mamcan"
                     /inference="alignment:Splign:2.1.0"
     exon            1669..1762
                     /gene="Mamdc2"
                     /gene_synonym="1200015L10Rik; mamcan"
                     /inference="alignment:Splign:2.1.0"
     exon            1763..1915
                     /gene="Mamdc2"
                     /gene_synonym="1200015L10Rik; mamcan"
                     /inference="alignment:Splign:2.1.0"
     exon            1916..2175
                     /gene="Mamdc2"
                     /gene_synonym="1200015L10Rik; mamcan"
                     /inference="alignment:Splign:2.1.0"
     exon            2176..2260
                     /gene="Mamdc2"
                     /gene_synonym="1200015L10Rik; mamcan"
                     /inference="alignment:Splign:2.1.0"
     exon            2261..3338
                     /gene="Mamdc2"
                     /gene_synonym="1200015L10Rik; mamcan"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3181..3186
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mamdc2"
                     /gene_synonym="1200015L10Rik; mamcan"
                     /note="hexamer: AATAAA"
     polyA_site      3203
                     /gene="Mamdc2"
                     /gene_synonym="1200015L10Rik; mamcan"
                     /note="major polyA site"
ORIGIN      
        1 aagtggtggc tggcccttct caagtgtgca gttgtctcct ccctgtccag tccggcagtc
       61 gcccggggcc caaccgggct acgagtggcc ggacgctaca gccttgcgca gcgcgctctg
      121 ctcctcagac tcttcgaatt tgagcagcct gtggcatccc ccagcaggtc ccccagctcc
      181 ttgcctagca ccctcccttc cctaggagca gcgggccaca gtgagccagc agccctcgcg
      241 ggtcctcctg cctgaagttc aactatgcta ctagaagggg tcctgctggt agtgcaagcc
      301 ttgcagcttg ccaatgccct agacctgccc gctggctcct gcgcctttga agaagacacg
      361 tgtggctttg actccgtgtt tgcgtttctg ccttggatac taaatgagga aggccattat
      421 gtctatatgg acacctcttt tgccaggcaa ggggagaaag ctgtgctgct gagttctgat
      481 ttgcaggctg aggagtggaa ctgtttgcgc ctggtctacc agataaccac acctccggga
      541 tctgtgtcag accccagcca gctgaacctc tatgtgagat ttgaggatga gagcttcgat
      601 cgcttgcttt ggtccactaa ggagccttca gacagctggc tcatagccag cctggatctt
      661 caaaacagct ccaagaaatt caagattttg atagaaggtg tcctgggaca aggaaacacg
      721 gctagcattg ccctctttga aatcaagatg acagccggct actgtattga atgtgacttt
      781 gaagaaaacc atctctgtgg ctttgtgaac cgctggaatc ccaatgtgaa ctggttcgtg
      841 ggaggaggaa ctgcgaagaa cacccactcc atcctcccac aggatcacac cttcaggagt
      901 gagcacggcc actacatgta tgtggactct gtgtatgtca agcacttcca ggaagtagcc
      961 cagctcatct ccccagtgac cacagcctcc atgtctggct gtctctcgtt ctattaccag
     1021 cttcagcagg ggaatgacaa tgtcttctct gtttacacac gggacatggc tggcctgtac
     1081 gaggagattt ggaaagtgga cagcccaggc aatgcagcct ggaaccttgc ggaggtggaa
     1141 tttagtgctc cttaccccat ggaggttatt tttgaagttg ctttcaatgg tcccaaagga
     1201 ggctacgttg ccctggatga tatttctttc tctcctgttc actgccaaaa tcagacaggg
     1261 cttcctttca gtgctgtgga aaccagctgc gattttgaga taggcctctg caacttttat
     1321 caagacaaag agggtccggg ttggaccaga gtaagagtaa aagcaaacat gtatcgggcc
     1381 ggagaccaca cgacaggaac agggcactac ctgctggcca acactaagtt tacatcccag
     1441 cctggctaca tcggaagact ttatggtccc tctctccctg gaaacatgca gtactgtgtg
     1501 cgctttcatt acgccatctt tgggtttttg aaaatgagtg acaccctagc cgtttatatc
     1561 tttgaagaaa accatgtggt tcaagagaag atctggtctg tgctcgagtc cccgaggggt
     1621 gtttggatgc aagcggaaat cagtttcaag aagcctatgc ccacaaaggt ggtttttatg
     1681 agcctgtgca aaagcttttg ggactgtggc ctggtagccc tggatgacat taccatacaa
     1741 ctaggaaact gccggtctcc agcaagactt ccacctccac ctggagaatg cacttttgat
     1801 caagatgaat gtgcgtttac acaggagaaa aggaaccgaa gcagctggca caggggaagg
     1861 ggagaaacgc ccacctccta cacaggaccc aagggagatc acactactgg ggtaggttac
     1921 tacatgtaca tcgaagcctc ccacatggtg tatggacaga aagcacacct tttgtcccag
     1981 cctctgagag gcgtccctgg gaaacactgc ttgacgtttt tctaccacat gtacggagca
     2041 gggactggcc tgctgagtgt ttatttgaaa agggaagaag atagtgagga gtccctgttg
     2101 tggagaagaa ggggagagca gagcatctcc tggctgcggg cactggttga atacagctgc
     2161 aggaggagac accagataat ttttgaagcc actcgaggag tgtccataag aagtgatatc
     2221 gccattgatg atgttaaact tcaggcaggg ccgtgtgcag gaatggaaga tacaactgaa
     2281 cagtcatcag gatattctga agacttaaat gaaatcgagt attaagaaat gatctaactt
     2341 agagcaagaa gacaaaagtt gtacctctct tcagtcaaag aggaaacaaa agaaatggat
     2401 actggatgct cttgactatt gcataagttg aaatgacttc agaagacccg ctctcgttac
     2461 ttttgaaaac tattatctct atgtattaac tcagggctct cctctgtttt cccccccagc
     2521 acatctgaca actgttacta gaagtacagg ctactggttt tacagaaacc atttcatctt
     2581 aattttggta ccagttaaaa taagaatgta ctgtgttaca gtcacttcag agtacacgta
     2641 taaagggcac aatcagagcg agtgtgctta taagcctgca ttcagtgaat gtattgggag
     2701 actaggtctt ggtggtgttc cttttgagtt tcaagaatga gaagttttct taaatagtaa
     2761 tgcaaggtca gtaatgtccg ccaaagggat gcagtgtttt atggtaacaa ttattctgga
     2821 aataaggtcg ccccatggag ccccaggata agtctgcgct aattcatgct gccttacggg
     2881 gcagtgccac cttttcttct ccatttctac tgccttggac agtcaccagg agcacctgaa
     2941 tagcaatgca ccttttcaac aaggcaagct tgaatttttt tatgcacata cactcaacaa
     3001 tttttataaa tgtgttaaac aatttgaccc atttttatca taaatatttt tagtgaaatt
     3061 tttagtagta tgagttcaac cacatttgat aaactatggt ttttttattg acttatttag
     3121 aattgtatat atgtgtgcaa ttgtgtggct aatcagctgt ctaaaacttc aaaattgcct
     3181 aataaaagat catttaaaaa tcctctcatt agcaattaac tcattactac attatttgtc
     3241 tttatcagaa catatccatt atataattgc aaattctaat ttgaagctct attctgccat
     3301 aattaaatgt tttaagtcac cttatcagtg acattact
//
