LOCUS       NM_178920               2775 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus mal, T cell differentiation protein 2 (Mal2), mRNA.
ACCESSION   NM_178920
VERSION     NM_178920.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2775)
  AUTHORS   Zhu,M., Jia,L., Li,F. and Jia,J.
  TITLE     Identification of KIAA0513 and Other Hub Genes Associated With
            Alzheimer Disease Using Weighted Gene Coexpression Network Analysis
  JOURNAL   Front Genet 11, 981 (2020)
   PUBMED   33005179
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2775)
  AUTHORS   Reginensi,A., Hoshi,M., Boualia,S.K., Bouchard,M., Jain,S. and
            McNeill,H.
  TITLE     Yap and Taz are required for Ret-dependent urinary tract
            morphogenesis
  JOURNAL   Development 142 (15), 2696-2703 (2015)
   PUBMED   26243870
REFERENCE   3  (bases 1 to 2775)
  AUTHORS   Bello-Morales,R., de Marco,M.C., Aranda,J.F., Matesanz,F.,
            Alcina,A. and Lopez-Guerrero,J.A.
  TITLE     Characterization of the MAL2-positive compartment in
            oligodendrocytes
  JOURNAL   Exp Cell Res 315 (19), 3453-3465 (2009)
   PUBMED   19683524
  REMARK    GeneRIF: after differentiation, murine oligodendrocyte precursor
            and human oligodendroglioma derived cell lines up-regulate the
            expression of MAL2 and accumulate it in an intracellular
            compartment, exhibiting a peri-centrosomal localization.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC115924.11.
            
            On Oct 27, 2009 this sequence version replaced NM_178920.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK035986.1, BC113154.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-272               AC115924.11        124301-124572
            273-443             AC115924.11        141249-141419
            444-599             AC115924.11        151346-151501
            600-2775            AC115924.11        153606-155781
FEATURES             Location/Qualifiers
     source          1..2775
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 21.37 cM"
     gene            1..2775
                     /gene="Mal2"
                     /note="mal, T cell differentiation protein 2"
                     /db_xref="GeneID:105853"
                     /db_xref="MGI:MGI:2146021"
     exon            1..272
                     /gene="Mal2"
                     /inference="alignment:Splign:2.1.0"
     CDS             144..671
                     /gene="Mal2"
                     /codon_start=1
                     /product="protein MAL2"
                     /protein_id="NP_849251.1"
                     /db_xref="CCDS:CCDS27470.1"
                     /db_xref="GeneID:105853"
                     /db_xref="MGI:MGI:2146021"
                     /translation="MSAGGAVPPPPNPAVSFPAPRVTLPAGPDILRTYSGAFVCLEIV
                     LGGLVWILVASSNVPLPLLQGWVMFVSVTAFFFSLLFLGLFLSGMVTQIDANWNFLDF
                     VYHFIVFVFYFGAFLLEAAATSLHDLQCNTTMTVKPLLNDNQYNINVAATVFAFMTTA
                     CYGCSLGLALRRWRP"
     exon            273..443
                     /gene="Mal2"
                     /inference="alignment:Splign:2.1.0"
     exon            444..599
                     /gene="Mal2"
                     /inference="alignment:Splign:2.1.0"
     exon            600..2775
                     /gene="Mal2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2751..2756
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Mal2"
                     /note="hexamer: AATAAA"
     polyA_site      2771
                     /gene="Mal2"
                     /note="major polyA site"
ORIGIN      
        1 accctttccg cgagcagcac gcctgaaccc cacggatcgg atcggcggcg gcggcggcgg
       61 cggcggccaa gcccgggagg cggcggcggg acgcgggagg cggtggcggc ggtggcggtg
      121 cgcggagacg tagcagcggc agcatgtcgg ccggcggagc agtcccgccg cccccgaacc
      181 ctgccgtgtc cttcccggcg ccccgggtca ccctgcccgc tggccccgac atcctaagga
      241 cgtactccgg agctttcgtc tgtctggaga ttgtgcttgg aggacttgtc tggattttgg
      301 ttgcttcctc caatgttcct ctacctctgc tccaaggatg ggtcatgttt gtgtcggtga
      361 cagctttctt cttttcgctt ctcttcctgg gcttgttcct ctctggtatg gtgactcaga
      421 ttgatgccaa ctggaacttc ctggattttg tctaccattt catagtcttt gtcttctact
      481 tcggagcgtt tttactggaa gcagcggcca cctccctgca tgaccttcag tgcaacacaa
      541 ccatgactgt gaagccacta ctcaacgaca accagtataa catcaacgtg gccgccacag
      601 tttttgcctt catgacaaca gcttgttatg gttgcagttt gggtctggct ttgcgaagat
      661 ggcgaccgta acactccttg gaaactgaca gttgtgtgct ggtttcattt gtctacttta
      721 tatgtctgat cacttgggta ccatttgtcc caatataaca ttccaaacat tgttagctta
      781 gtacagagag gacctcagtg caagctgtgg tttgttacat gggtgggatt ttcattttgt
      841 tctgatgtta gagaagtatc ctttcctttt tcatctctcg tttcttttta aatgcatttc
      901 cattgtatat tcttaaaata cacaggcact gttcacaaaa caatagtatt cctttttttt
      961 ttttttggtt gagtcacccg aaccttaata atagtaaata actaaaacaa tacatctcat
     1021 gcaggcttct catctaattc tatctttagt ataaaacagg aaatgataca catgtttttt
     1081 ttacaaaaag gccaggtagc acatatgtag gctttaatag gccatatagc ctctgtggca
     1141 attgttccat cctatgataa cataaaagca gctacagatg atgtgtaaat aaatgtctgt
     1201 atcctaataa agcttatttc aaaaagggag caaaactgga tgtggtctac agaccataat
     1261 tttatcaact actgccataa aaaccttagg tgttctgtgt tctattgaac taatcatgaa
     1321 acctcattag acaagccaca taacatattt tgtttcatta tgcatcaatc acattgcctt
     1381 tgtttaatag tcaaatatta cccttggaag gtcatataat ttctcaagct aaccccagca
     1441 gagccttgga tgaagagcaa aataaggtag gaaataaact ccaaactaat gatttcctaa
     1501 tagctcagca aggcactcac acgagagtac ttaagacatg atccccagag gcaattaatc
     1561 actactggat ctagtatctt gctactgatg tctttctttt ggtttattta tgccatagac
     1621 tgtggttgtt tggcctatgc atgaatatat aaatatttat gtatgtaaag cttttccaaa
     1681 tagctctctg aagagttgaa tttttaactt cttattgttt ttgcattgct ttctgagctg
     1741 aatttgagta acagattaac tataacataa agctatagat tcttacatgc tttgataata
     1801 gcccagatat ctatgttgtt tttacattgg tgtcagacag gcaaaggaca tttaacacaa
     1861 gagctaaaac aaaaactgga tctggctgaa tagaacagaa aacaatccta gtccacctgt
     1921 atgtgtcgca ggcttggcaa cagatcatga gtgaccacag ttcccaccgc attctcatac
     1981 aggccaattc cctattgttt tagtagggct gcctttggaa atggaggctt gggaattgct
     2041 ctcgagctga cccatcacct aagagtgcca tgtatggttg gagtattgga ctccctggaa
     2101 catagtgaaa aacatgaatg aatagcatca atgcccagtg ttcaagtgct gtttatctaa
     2161 tactccccca gaagaagaac caacggggac ctcagtttgt aatacagctg aagacgagat
     2221 gtatttctat atgtaggttg aagaaatcag tcttatggct ttccactcat gtcttagctc
     2281 ttctaaaatg ccagacttcc ctcctgtttt tccagctcca gaccacacac tgaaaaacct
     2341 gtattatgaa ttatatacta tgaagtcaca aatgtgccat aaagatacat tgtacgtgga
     2401 atcactaaaa tgtagtccac tagaatttag ttgagatttt tgttttcccc caggtgtacc
     2461 aagccatgct cagtgtggta ttaactcaaa tgaattcatt cagatgtatt ggtggtactt
     2521 ttgtaaatgt atggcttcta ggttagcaaa aagaaaactc aaagctgact aactgtgaat
     2581 acttaggtct gtagattcat tgcattctag atgttgtgag ctgagcgatg aagcacttga
     2641 acaaagacga aggtgtttaa gaatctctct acgtatctta gctgtaaaaa tgaaaaagtg
     2701 ttggctggtc ttaaaatctg ataaatttat tttataagtg ttatgactct aataaagtat
     2761 tcatttgata acctt
//
