LOCUS       NM_018832               2802 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus MAGI family member, X-linked (Magix), transcript
            variant 1, mRNA.
ACCESSION   NM_018832 XM_906269
VERSION     NM_018832.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2802)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2802)
  AUTHORS   Lin,Q., Donahue,S.L., Moore-Jarrett,T., Cao,S., Osipovich,A.B. and
            Ruley,H.E.
  TITLE     Mutagenesis of diploid mammalian genes by gene entrapment
  JOURNAL   Nucleic Acids Res 34 (20), e139 (2006)
   PUBMED   17062627
REFERENCE   3  (bases 1 to 2802)
  AUTHORS   Brunkow,M.E., Jeffery,E.W., Hjerrild,K.A., Paeper,B., Clark,L.B.,
            Yasayko,S.A., Wilkinson,J.E., Galas,D., Ziegler,S.F. and
            Ramsdell,F.
  TITLE     Disruption of a new forkhead/winged-helix protein, scurfin, results
            in the fatal lymphoproliferative disorder of the scurfy mouse
  JOURNAL   Nat Genet 27 (1), 68-73 (2001)
   PUBMED   11138001
REFERENCE   4  (bases 1 to 2802)
  AUTHORS   Means,G.D., Toy,D.Y., Baum,P.R. and Derry,J.M.
  TITLE     A transcript map of a 2-Mb BAC contig in the proximal portion of
            the mouse X chromosome and regional mapping of the scurfy mutation
  JOURNAL   Genomics 65 (3), 213-223 (2000)
   PUBMED   10857745
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC099459.1 and AK158091.1.
            
            On Mar 24, 2007 this sequence version replaced NM_018832.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the supported protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC099459.1, AF229645.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849385, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1341              BC099459.1         1-1341
            1342-2802           AK158091.1         1282-2742
FEATURES             Location/Qualifiers
     source          1..2802
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 3.46 cM"
     gene            1..2802
                     /gene="Magix"
                     /gene_synonym="Pdzx; Sfc18"
                     /note="MAGI family member, X-linked"
                     /db_xref="GeneID:54634"
                     /db_xref="MGI:MGI:1859644"
     exon            1..140
                     /gene="Magix"
                     /gene_synonym="Pdzx; Sfc18"
                     /inference="alignment:Splign:2.1.0"
     CDS             92..1066
                     /gene="Magix"
                     /gene_synonym="Pdzx; Sfc18"
                     /note="PDZ domain containing X chromosome"
                     /codon_start=1
                     /product="PDZ domain-containing protein MAGIX"
                     /protein_id="NP_061302.2"
                     /db_xref="CCDS:CCDS29968.1"
                     /db_xref="GeneID:54634"
                     /db_xref="MGI:MGI:1859644"
                     /translation="MDSRAGNTADPRGGRRGGGLQGSRSPRARQLLERLDARPLAARA
                     AADLTALVRKAGATLRLRHTEGVSGLDSADIEVTDSRLPHATLVKHRPQHQRSETLGT
                     WTEPLPVTQNKASYALKVPQATGRFSVELTRGPAGFGLTLSGGRNVSGDAPLTVHGLL
                     KDGPAQRCGRLQAGDLVLYINGQSTQGLTHAQVVERIRTGGPHLCLVLQRPQDMDGSR
                     IKEVGGHRKTDRSLDPRGSRVESRSTISPVHHRPKTRTSPRPSPEAVAIGHVVRAVEH
                     PTEDLENRIPGTPGPWLVPSEDRLSRALGVRGGGAQLALEMAAGRRRH"
     exon            141..287
                     /gene="Magix"
                     /gene_synonym="Pdzx; Sfc18"
                     /inference="alignment:Splign:2.1.0"
     exon            288..370
                     /gene="Magix"
                     /gene_synonym="Pdzx; Sfc18"
                     /inference="alignment:Splign:2.1.0"
     exon            371..607
                     /gene="Magix"
                     /gene_synonym="Pdzx; Sfc18"
                     /inference="alignment:Splign:2.1.0"
     exon            608..776
                     /gene="Magix"
                     /gene_synonym="Pdzx; Sfc18"
                     /inference="alignment:Splign:2.1.0"
     exon            777..2802
                     /gene="Magix"
                     /gene_synonym="Pdzx; Sfc18"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1323..1328
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Magix"
                     /gene_synonym="Pdzx; Sfc18"
                     /note="hexamer: AATAAA"
     polyA_site      1341
                     /gene="Magix"
                     /gene_synonym="Pdzx; Sfc18"
                     /note="major polyA site"
ORIGIN      
        1 tccaggcctg ggctaggagc caggtgagcg cgcccctgcg ctaaaaacta atcatcgggc
       61 tgccctgagt ccaccaggtt caccacaggc catggactct cgcgctggga acacggcaga
      121 ccctagaggg ggcagaagag gaggtggctt acaagggtcc aggagtcccc gagctcggca
      181 gctcctggag cggctggatg cgcgccccct ggcggcacga gccgccgcgg acttgacagc
      241 gctagtacga aaagcgggcg ccacattgcg cctgcgccac acggagggtg ttagtggtct
      301 ggattctgca gatatagaag tcacagacag tcgcttgcct catgctactc ttgtgaaaca
      361 tcgaccccag catcaaaggt ctgagactct aggtacatgg acggagccac ttccagtaac
      421 ccagaataag gcaagctatg ctttgaaagt accccaagcc actggccgat tttctgtgga
      481 gctgacccga ggtccggcag gttttggtct cactttaagt ggaggccgaa atgtatctgg
      541 ggatgctcca ttgaccgtgc atggactgct gaaggatggg ccagcacagc gatgtggtcg
      601 tttgcaggct ggtgacctcg tgctctatat caatggccag tcaacacagg gccttactca
      661 tgcccaggtg gtggagagga ttcgaactgg aggcccccac ctttgcctgg tacttcaaag
      721 gcctcaagac atggatggca gtaggatcaa ggaggttgga ggacatcgga agacagatcg
      781 cagcctagat cctaggggaa gcagggtgga gtctcgcagc accatttccc cagttcacca
      841 ccggcccaag acccggacca gtcccagacc tagtccagag gcagtggcta ttggccacgt
      901 ggttcgcgca gtggagcacc ccacagaaga cctggaaaac cgtatccctg gtacccctgg
      961 gccctggctg gtgcccagcg aggaccggct ctcgcgggct ctaggggttc ggggtggggg
     1021 cgcgcagctt gctctggaga tggcagccgg aaggcggagg cattgagcac caatagacag
     1081 ctttgtgctc actaggtgag gtcccataag gttctagcat gcaggaccgc caggctctaa
     1141 gcttttccct tagagcttta acctggttta gtaccttccc actgcacatt gcacagtgga
     1201 gtggtcccca ccccttcaag acgccagtgg tatggccctc ccagagccca gagcgctcgc
     1261 accccaccac ccccacgtcc gcgtgcgcgc agcttctcct agtcccttcc cgaccgggag
     1321 gtaataaaat agttggatcc agttctgact tgctaggtgc tctaggcggg gtgaggtttc
     1381 ccagtccacc ctggaaggga ggggtggctt gatctggttt cgatgaagtc ccttcgaaac
     1441 cacccgaaag ctacgtgcag cttccttcat gcctccagat gggtctttat ttctgcttgc
     1501 ttcccagttt gctttgctaa tccctgccct tcattcattc atttcacttt ccgagtacgc
     1561 acattactgc ttgtgatgtg gggaatgcag aagtaggcct gttgtgggag tgtcccagta
     1621 aactcaggat tcccgcatgg aattcttcag acccttagct gacatcaaga tagcaaatct
     1681 agaattctgg cgccttcctc cacccagagt ctgtggtctc ccacttccgg cttggaaaaa
     1741 ctagctttaa ctgtggtgta tagactgctg tcccaggggc gcgggctggg gccttggacc
     1801 ccacttggag acagagcggg gaaggtgtga gtcagcgcct ccagtaggcc aggctaaaaa
     1861 gggctgttag aagaagtctt tgggccacgc ctcctctttt ccttagacgg tgacaaactg
     1921 caccaggcgg tcctagcctg ggacgagact aaagtttcct ccgccctggg agttgaatcc
     1981 tactgtcaaa agcttatatg gacagtagac tccaacccag ggagccacaa agcaggtcct
     2041 ggccaatgct acaaatgtcc agtcaccttg ctgctaacca catcctgcat cctcaatccc
     2101 atcccccaaa gagggaagtt gtggtctaaa caggcaactt tcccccccac cccataagga
     2161 ggaggggggg aaggggagaa atgacaggtc ctgagtctca ggtggcagtg ggggtggggt
     2221 ggggcagact gcaatccgaa cagggacagc tagcagctgg ggtataaaaa agtgagcact
     2281 tgaagtgtta gtgtgtggtg acatgtgact cagagtacag tgggagtatg gttccccaga
     2341 agtcaggaaa gggttctagt acacagttcc taaacagcca cacccagggg actaatatag
     2401 taacctcagc caccatttac ttagtttagc tttaccctgc tactagcttt aatgggggtt
     2461 tttatttcat ctacttacat gcctactcag cattaggtca tttcccaaag ggggaaaacg
     2521 aggcccagcg atcgcaaata gactggatgg tggagagctc aaagcaggat tagttaaagc
     2581 ttggtttgga agcctttcct cataatctta accgtatttg acaagtccca gttgaacctc
     2641 gaccatatac ctgctctaga gtagttctac agtgactcca gggatagtaa aagtagacca
     2701 gtgtcagaca agaatgacaa gaatccataa aagataactt ccaagagaat tgatagttac
     2761 agaaataata ataataatga taataataat aaaggttatg gc
//
