LOCUS       NM_019791               2703 bp    mRNA    linear   ROD 11-FEB-2025
DEFINITION  Mus musculus MAGE family member D1 (Maged1), transcript variant 1,
            mRNA.
ACCESSION   NM_019791 XM_980479
VERSION     NM_019791.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2703)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2703)
  AUTHORS   Cheron,J., Beccari,L., Hague,P., Icick,R., Despontin,C.,
            Carusone,T., Defrance,M., Bhogaraju,S., Martin-Garcia,E.,
            Capellan,R., Maldonado,R., Vorspan,F., Bonnefont,J. and de Kerchove
            d'Exaerde,A.
  TITLE     USP7/Maged1-mediated H2A monoubiquitination in the paraventricular
            thalamus: an epigenetic mechanism involved in cocaine use disorder
  JOURNAL   Nat Commun 14 (1), 8481 (2023)
   PUBMED   38123574
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2703)
  AUTHORS   Wang,J., Xu,S.Y., Ye,Z.Y., Sun,Z.N., Zhang,J.Q., Qi,C., Liu,R.,
            Gao,X., He,C., You,W.Y. and Gao,J.
  TITLE     The deficiency of Maged1 attenuates Parkinson's disease progression
            in mice
  JOURNAL   Mol Brain 16 (1), 22 (2023)
   PUBMED   36774489
  REMARK    GeneRIF: The deficiency of Maged1 attenuates Parkinson's disease
            progression in mice.
            Erratum:[Mol Brain. 2024 Feb 9;17(1):6. doi:
            10.1186/s13041-023-01075-1.. PMID: 38336723]
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2703)
  AUTHORS   Yuan,H., Xie,B., Yu,X., Lin,C., Li,M., Zhang,Y., Zou,X., Lu,M.,
            Zhao,M. and Wen,X.
  TITLE     A potential role of p75NTR in the regulation of circadian rhythm
            and incremental growth lines during tooth development
  JOURNAL   Front Physiol 13, 981311 (2022)
   PUBMED   36213234
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2703)
  AUTHORS   Park,S., Kwon,W., Kim,H.Y., Ji,Y.R., Kim,D., Kim,W., Han,J.E.,
            Cho,G.J., Yun,S., Kim,M.O., Ryoo,Z.Y., Han,S.H., Park,J.K. and
            Choi,S.K.
  TITLE     Knockdown of Maged1 inhibits cell cycle progression and causes cell
            death in mouse embryonic stem cells
  JOURNAL   Differentiation 125, 18-26 (2022)
   PUBMED   35349880
  REMARK    GeneRIF: Knockdown of Maged1 inhibits cell cycle progression and
            causes cell death in mouse embryonic stem cells.
REFERENCE   6  (bases 1 to 2703)
  AUTHORS   Shiras,A., Sengupta,A. and Shepal,V.
  TITLE     Cloning and tissue-specific gene expression studies with Dlxin-1, a
            newly identified transcriptional activator
  JOURNAL   Mol Cell Biol Res Commun 4 (5), 313-319 (2001)
   PUBMED   11529682
REFERENCE   7  (bases 1 to 2703)
  AUTHORS   Chomez,P., De Backer,O., Bertrand,M., De Plaen,E., Boon,T. and
            Lucas,S.
  TITLE     An overview of the MAGE gene family with the identification of all
            human members of the family
  JOURNAL   Cancer Res 61 (14), 5544-5551 (2001)
   PUBMED   11454705
REFERENCE   8  (bases 1 to 2703)
  AUTHORS   Masuda,Y., Sasaki,A., Shibuya,H., Ueno,N., Ikeda,K. and Watanabe,K.
  TITLE     Dlxin-1, a novel protein that binds Dlx5 and regulates its
            transcriptional function
  JOURNAL   J Biol Chem 276 (7), 5331-5338 (2001)
   PUBMED   11084035
REFERENCE   9  (bases 1 to 2703)
  AUTHORS   Kubu,C.J., Goldhawk,D.G., Barker,P.A. and Verdi,J.M.
  TITLE     Identification of the translational initiation codon in human
            MAGED1
  JOURNAL   Genomics 70 (1), 150-152 (2000)
   PUBMED   11087672
REFERENCE   10 (bases 1 to 2703)
  AUTHORS   Salehi,A.H., Roux,P.P., Kubu,C.J., Zeindler,C., Bhakar,A.,
            Tannis,L.L., Verdi,J.M. and Barker,P.A.
  TITLE     NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin
            receptor and facilitates nerve growth factor-dependent apoptosis
  JOURNAL   Neuron 27 (2), 279-288 (2000)
   PUBMED   10985348
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL627302.20.
            
            On Jul 26, 2018 this sequence version replaced NM_019791.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB029448.1, AK049660.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-134               AL627302.20        190070-190203       c
            135-208             AL627302.20        189429-189502       c
            209-901             AL627302.20        188033-188725       c
            902-1576            AL627302.20        186785-187459       c
            1577-1640           AL627302.20        186623-186686       c
            1641-1720           AL627302.20        186362-186441       c
            1721-1812           AL627302.20        186152-186243       c
            1813-1892           AL627302.20        185854-185933       c
            1893-1935           AL627302.20        185720-185762       c
            1936-1998           AL627302.20        185472-185534       c
            1999-2113           AL627302.20        185052-185166       c
            2114-2499           AL627302.20        184038-184423       c
            2500-2703           AL627302.20        183652-183855       c
FEATURES             Location/Qualifiers
     source          1..2703
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 41.56 cM"
     gene            1..2703
                     /gene="Maged1"
                     /gene_synonym="2810433C11Rik; 5430405L04Rik; Dlixin;
                     Dlxin-1; Dlxin1; DXBwg1492e; MAGE-D1; NRAGE"
                     /note="MAGE family member D1"
                     /db_xref="GeneID:94275"
                     /db_xref="MGI:MGI:1930187"
     exon            1..134
                     /gene="Maged1"
                     /gene_synonym="2810433C11Rik; 5430405L04Rik; Dlixin;
                     Dlxin-1; Dlxin1; DXBwg1492e; MAGE-D1; NRAGE"
                     /inference="alignment:Splign:2.1.0"
     exon            135..208
                     /gene="Maged1"
                     /gene_synonym="2810433C11Rik; 5430405L04Rik; Dlixin;
                     Dlxin-1; Dlxin1; DXBwg1492e; MAGE-D1; NRAGE"
                     /inference="alignment:Splign:2.1.0"
     CDS             164..2491
                     /gene="Maged1"
                     /gene_synonym="2810433C11Rik; 5430405L04Rik; Dlixin;
                     Dlxin-1; Dlxin1; DXBwg1492e; MAGE-D1; NRAGE"
                     /note="MAGE-D1 antigen; neurotrophin receptor-interacting
                     MAGE homolog; melanoma antigen, family D, 1"
                     /codon_start=1
                     /product="melanoma-associated antigen D1"
                     /protein_id="NP_062765.1"
                     /db_xref="CCDS:CCDS30280.1"
                     /db_xref="GeneID:94275"
                     /db_xref="MGI:MGI:1930187"
                     /translation="MAQKPDGGAGLRGFQAEASVEDSALLVQTLMEAIQISEAPPTSQ
                     ATAAASGPNASPQSSQPPTANEKADTEVSAAAARPKTGFKAQNATTKGPNDYSQARNA
                     KEMPKNQSKAAFKSQNGTPKGPHAASDFSQAAPTGKSAKKSEMAFKGQNSTKAGPGTT
                     YNFPQSPSANEMTNNQPKTAKAWNDTTKVPGADAQTQNVNQAKMADVGTSAGISEADG
                     AAAQTSADGSQTQNVESRTIIRGKRTRKVNNLNVEENNSGDQRRASLASGNWRSAPVP
                     VTTQQNPPGAPPNVVWQTPLAWQNPSGWQNQTARQTPPAARQSPPARQTPSAWQNPVA
                     WQNPVIWPNPVIWQNPVIWPNPIVWPGPIVWPNPMAWQSTPGWQSPPSWQAPPSWQSP
                     QDWQGPPDWQVPPDWSMPPDWSFPSDWPFPPDWIPADWPIPPDWQNLRPSPNLRSSSN
                     SRASQNQGPPQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPE
                     IIERACFVLEKKFGIQLKEIDKEEHLYILISTPESLAGILGTTKDTPKLGLLLVILGI
                     IFMNGNRATEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNP
                     PEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAE
                     ARAEARNRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFWARYHQNAR
                     SRFPQAFTGPIIGPSGTATANFAANFGAIGFFWVE"
     exon            209..901
                     /gene="Maged1"
                     /gene_synonym="2810433C11Rik; 5430405L04Rik; Dlixin;
                     Dlxin-1; Dlxin1; DXBwg1492e; MAGE-D1; NRAGE"
                     /inference="alignment:Splign:2.1.0"
     exon            902..1576
                     /gene="Maged1"
                     /gene_synonym="2810433C11Rik; 5430405L04Rik; Dlixin;
                     Dlxin-1; Dlxin1; DXBwg1492e; MAGE-D1; NRAGE"
                     /inference="alignment:Splign:2.1.0"
     exon            1577..1640
                     /gene="Maged1"
                     /gene_synonym="2810433C11Rik; 5430405L04Rik; Dlixin;
                     Dlxin-1; Dlxin1; DXBwg1492e; MAGE-D1; NRAGE"
                     /inference="alignment:Splign:2.1.0"
     exon            1641..1720
                     /gene="Maged1"
                     /gene_synonym="2810433C11Rik; 5430405L04Rik; Dlixin;
                     Dlxin-1; Dlxin1; DXBwg1492e; MAGE-D1; NRAGE"
                     /inference="alignment:Splign:2.1.0"
     exon            1721..1812
                     /gene="Maged1"
                     /gene_synonym="2810433C11Rik; 5430405L04Rik; Dlixin;
                     Dlxin-1; Dlxin1; DXBwg1492e; MAGE-D1; NRAGE"
                     /inference="alignment:Splign:2.1.0"
     exon            1813..1892
                     /gene="Maged1"
                     /gene_synonym="2810433C11Rik; 5430405L04Rik; Dlixin;
                     Dlxin-1; Dlxin1; DXBwg1492e; MAGE-D1; NRAGE"
                     /inference="alignment:Splign:2.1.0"
     exon            1893..1935
                     /gene="Maged1"
                     /gene_synonym="2810433C11Rik; 5430405L04Rik; Dlixin;
                     Dlxin-1; Dlxin1; DXBwg1492e; MAGE-D1; NRAGE"
                     /inference="alignment:Splign:2.1.0"
     exon            1936..1998
                     /gene="Maged1"
                     /gene_synonym="2810433C11Rik; 5430405L04Rik; Dlixin;
                     Dlxin-1; Dlxin1; DXBwg1492e; MAGE-D1; NRAGE"
                     /inference="alignment:Splign:2.1.0"
     exon            1999..2113
                     /gene="Maged1"
                     /gene_synonym="2810433C11Rik; 5430405L04Rik; Dlixin;
                     Dlxin-1; Dlxin1; DXBwg1492e; MAGE-D1; NRAGE"
                     /inference="alignment:Splign:2.1.0"
     exon            2114..2499
                     /gene="Maged1"
                     /gene_synonym="2810433C11Rik; 5430405L04Rik; Dlixin;
                     Dlxin-1; Dlxin1; DXBwg1492e; MAGE-D1; NRAGE"
                     /inference="alignment:Splign:2.1.0"
     exon            2500..2703
                     /gene="Maged1"
                     /gene_synonym="2810433C11Rik; 5430405L04Rik; Dlixin;
                     Dlxin-1; Dlxin1; DXBwg1492e; MAGE-D1; NRAGE"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2678..2683
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Maged1"
                     /gene_synonym="2810433C11Rik; 5430405L04Rik; Dlixin;
                     Dlxin-1; Dlxin1; DXBwg1492e; MAGE-D1; NRAGE"
                     /note="hexamer: AATAAA"
     polyA_site      2703
                     /gene="Maged1"
                     /gene_synonym="2810433C11Rik; 5430405L04Rik; Dlixin;
                     Dlxin-1; Dlxin1; DXBwg1492e; MAGE-D1; NRAGE"
                     /note="major polyA site"
ORIGIN      
        1 gagctgccgc gctggcattt tctcctggac gcggagagag tgcgggtgcc gagagccgga
       61 cagagccatt cccgatcctc ttgagtcgcg aagaaggaaa cagcgaaggg attggggttc
      121 ggccctgagg caaggctctg ctcttgccag ggagacgaga gctatggctc agaaaccgga
      181 cggcggtgca ggcctccgcg gcttccaggc tgaggcctct gttgaagaca gcgccttgct
      241 tgtgcagacc ttgatggaag ccatccagat ctccgaggct ccgcccacca gccaggccac
      301 agcagctgcc agtgggccaa atgctagtcc ccagagttca cagcccccaa ctgccaatga
      361 gaaggctgat actgaggttt cagcagctgc tgccaggcct aagacaggct ttaaggccca
      421 gaatgccacc acaaaggggc caaatgatta ctctcaggca cgtaatgcca aggagatgcc
      481 caagaatcag tctaaggcgg cctttaagtc acagaatggc acccctaaag gtccacatgc
      541 tgcctctgac ttttcccagg cagcacccac aggcaaatca gctaaaaagt ctgaaatggc
      601 ctttaagggt cagaatagca ctaaggctgg ccccggtacc acctacaatt tccctcagtc
      661 tcccagtgcc aatgagatga ccaacaacca gcctaagaca gctaaggctt ggaatgacac
      721 tactaaggtc cctggagctg atgcccagac ccagaatgta aatcaggcca aaatggctga
      781 cgtagggacc agcgcaggta tctctgaagc tgatggtgca gcagcccaga catcagcaga
      841 tggctcccag actcagaacg tggagtcccg gactataatt cggggcaaga ggacccgcaa
      901 ggttaataac ttgaatgtgg aagagaacaa cagtggggat caaaggcgtg cctcactggc
      961 ctcagggaac tggaggtctg ctccggttcc agtgaccact cagcagaacc cacctggagc
     1021 accccctaat gtggtgtggc agacaccact ggcttggcag aacccatcag gctggcaaaa
     1081 ccagacagcc aggcagaccc caccagcagc acgtcagagt cccccagcta ggcagacacc
     1141 atcagcttgg cagaacccag ttgcatggca gaatccagtg atctggccta acccagtgat
     1201 ctggcagaat ccagtgatct ggccaaaccc cattgtctgg cctggcccaa ttgtctggcc
     1261 aaacccaatg gcctggcaga gtacacctgg atggcagagc ccacccagct ggcaggctcc
     1321 acctagttgg cagagccctc aagattggca gggccctcca gattggcagg taccacctga
     1381 ctggtcaatg cctcctgact ggtcctttcc ctccgactgg ccttttccac ctgactggat
     1441 ccccgccgac tggccaattc cacctgactg gcagaactta cgaccctcac ctaatctgag
     1501 atcctcctcc aactctcgtg cctcacagaa ccagggtcct ccacagcccc gagatgtggc
     1561 ccttcttcag gaaagagcaa ataagttggt caagtacctg atgcttaaag actacacgaa
     1621 ggtgcccatc aagcgctcag aaatgctgag ggatatcatc cgagaataca ctgatgtcta
     1681 tccagaaatc attgagcgcg catgctttgt cctggagaag aaatttggaa tccagctgaa
     1741 ggaaatcgac aaagaagagc atctgtatat tctcatcagt acccctgagt ccctggctgg
     1801 catactggga acgaccaaag acacaccgaa gcttggcctc ctcttagtga ttctgggcat
     1861 tatcttcatg aatggcaacc gtgccaccga ggccgtcctc tgggaagcac tgcgcaagat
     1921 gggactacgt cctggggtga gacatcccct ccttggtgac ctgagaaaac ttcttactta
     1981 cgagtttgta aagcagaaat acctggacta tagacgagtg cccaacagca accctcctga
     2041 gtatgagttc ctctggggcc tccgctccta ccatgagact agcaagatga aagtgctgag
     2101 attcattgca gaggttcaga agagagaccc tcgtgactgg actgcacagt tcatggaagc
     2161 tgcagatgaa gccttggatg ctctggatgc tgctgcagct gaggcagagg cccgggctga
     2221 agcgagaaac cgcatgggaa ttggagatga ggctgtgtct ggtccctgga gctgggatga
     2281 cattgagttt gagctgctga cctgggatga ggaaggagat tttggagatc cttggtccag
     2341 gatccccttt accttctggg ccagatacca ccagaatgcc cgctccaggt ttccccaggc
     2401 ctttactggc cccatcattg gccccagtgg tactgccacc gccaacttcg ccgccaactt
     2461 cggtgccatt ggcttcttct gggttgagta aattgtcaga tactgctcat catttgcaat
     2521 agttttccct gagtgaggct gaagcctcag gttccttcaa aacacgctat ctagagagcc
     2581 acatcctgtt gactgagagt ggcatgcaaa atacatttat ttgctattct gtcttacttt
     2641 tttttttcct tgtgtgttgt caagttttgg tatcagaaat aaatgttgaa attgcaaagt
     2701 gaa
//
